Acrospiroma is a rare benign tumor and a clinicopathologically distinctive neoplasm differentiating toward the distal part of the eccrine sweat gland. I experienced a case of dermal acrospiroma in a 59-year-old man who had a 7.0x6.5 x 5.3 cm sized, slowly growing, brown colored, smooth-surfaced mass on the right scrotum for 3 years. Histological examination revealed lobular structures composed of small fusiform cells and large eosinophilic polyhedral cells. Histochemically some of large polyhedral cells had PAS-positive DPAS-negative glycogen and Alcian-positive mucin in cytoplasm. Immunohistochemical stainings for vimentin, S-100, low molecule keratin, and EMA were positive in the tumor cells. During 6 months follow up period after excision, there was no recurrence. However, it is necessary to follow up for a long period because some acrospiroma may recur after a long silence period.
Acrospiroma* ; Cytoplasm ; Eosinophils ; Follow-Up Studies ; Glycogen ; Humans ; Middle Aged ; Mucins ; Recurrence ; Scrotum* ; Sweat Glands ; Vimentin

No abstract available.

PURPOSE: To determine if the urine specific gravity(SG) plays a role in enuresis, the first morning urine SG of the healthy preschool nocturnal enuretic was compared with that of the nonenuretic. The results of desmopressin were analyzed according to the pretreatment urine SG to know if the urine SG can predict the responsiveness of the medication. MATERIALS AND METHODS: Five hundred twenty healthy preschool children aged 3-6 years were entered in this prospective observer-blinded study. A comparison was made between SG of the first morning urine specimen and results of questionnaire concerning the bed wetting and voiding habits of children. The responsiveness to oral desmopressin(0.2-0.4mg h.s.) in 14-day treatment periods was also analyzed according to the urine SG in 28 children with enuresis. The responder group was defined as a reduction of at least 50% from the number of wet night. RESULTS: The incidence of enuresis was 8.6 percent. Stastistically significant difference was found between the bedwetter and nonbedwetter group with regard to the urine SG(p<0.05). The overall response rate of desmopressin was 68 percent. There was no significant difference between the responder and nonresponder group with respect to urine SG. CONCLUSIONS: The first morning urine of the enuretic showed higher probability of lower level of the SG than that of the nonenuretic. Treatment with desmopressin was associated with a significant decrease in the number of wet night, but clinical response was not predictable based on the first morning urine SG.
Child ; Child, Preschool* ; Deamino Arginine Vasopressin ; Enuresis* ; Humans ; Incidence ; Prospective Studies ; Surveys and Questionnaires

No abstract available.
Diagnosis* ; Ultrasonography* ; Varicocele*

No abstract available.
Urinary Bladder Neoplasms* ; Urinary Bladder*

Surgical results of 34 children (68 ureters) who underwent Cohen ureteral reimplantation in the last 6 years were evaluated. All children were followed at least 4 months after the operation. Indication for the repair consisted of vesicoureteral reflux in 22 children, obstructive megaureter in 8 children and ureterocele in 4 children. The underlying problems in 55 ureters ( 94.8% ) were successfully corrected. Surgical failures were persistent reflux in 2 ureters, new ipsilateral reflux in 1 ureter and contralateral reflux in 1 ureter. However, no ureteral obstruction was noticed in this series. In conclusion, the Cohen cross trigonal technique was a safe and effective method of ureteral reimplantation in children.
Child* ; Humans ; Replantation* ; Ureter* ; Ureteral Obstruction ; Ureterocele ; Vesico-Ureteral Reflux

PURPOSE: Penile paraffinoma provokes many serious undesirable effects. We studied our series retrospectively to evaluate the outcome of surgical treatment according to the degree of penile skin defect after excision of the lesion. PATIENTS AND METHODS: Surgical treatment for penile paraffinoma was performed in 42 patients over 6 years. The operative methods were complete excision with primary closure (N=34) or bilateral pedicle scrotal flap (N=8). RESULT: The complications of bilateral pedicle scrotal flap were wound infection in 1 case and skin defect in 1 case. There were no complications of primary closure. CONCLUSIONS: We propose that the proper treatment of penile paraffinoma is complete excision with primary closure for a small denuded penis and bilateral pedicle scrotal flap for a large denuded penis.
Humans ; Male ; Paraffin ; Penis ; Retrospective Studies ; Skin ; Wound Infection

We evaluated a clinical usefulness of prostate specific antigen (PSA) as a tumor marker for prostate cancer. Serum PSA values were obtained from 32 patients with prostatic adenocarcinoma(group I ),81 with histologically diagnosed BPH(group II ) and 147 with clinically diagnosed BPH(group III). Mean PSA values were 121.5, 9.3 and 3.6ng/ml, respectively. To enhance the accuracy of serum PSA, we have used the quotient of serum PSA and prostatic volume, PSA density. In group I, 31 patients(97%) had PSA values over 10ng/ml and PSA density over 0.15. In group II, 27 patients(33%) had PSA values over 10ng/ml and 35(43%) had PSA density over 0.15. The PSA values of extraprostatic cancer were higher than that of organ-confined cancer in group I (p<0.05). Among 3 groups divided by combined Gleason score, low 2-4, intermediate 5-7 and high 8-l0, statistically significant differences were not noticed in PSA values (p > 0.05). Of 18 patients with stage D2 prostate cancer treated with orchiectomy, 11 had PSA values decreased to normal range within 6 months. Serum PSA values of 2 patients who have clinically progressive disease were increased after 6 months. In 3 of 4 patients treated with radiotherapy during follow-up of 18 months, post irradiation PSA values were 2.4, 5.6 and 11.2ng/ml, respectively. Only 1 patient who have a positive bone scan had an elevated PSA value of more than 100ng/ml. We suggest that serum PSA is not a excellent marker on screening test for prostate cancer because of a high false positive rate. However, PSA is useful for following disease progression, response to therapy and determining indication of bone scan.
Disease Progression ; Follow-Up Studies ; Humans ; Mass Screening ; Neoplasm Grading ; Orchiectomy ; Prostate* ; Prostate-Specific Antigen* ; Prostatic Neoplasms* ; Radiotherapy ; Reference Values

Ureterocele is a cystic dilatation of the intravesical segment of the ureter. In the ectopic ureterocele the ureteral orifice opens at a point other than its normal upper pole position, usually at the bladder neck or in the urethra, and is commonly associated with the upper moiety of a duplicated collecting system. Reflux into the ipsilateral lower pole ureter occurs in almost 50 per cent of ectopic ureterocele. But reflux into the ureterocele is rare. Recently we experienced a case of ectopic ureterocele associated with reflux into the ureterocele and treated successfully by heminephrectomy and total ureterectomy.
Dilatation ; Neck ; Ureter ; Ureterocele* ; Urethra ; Urinary Bladder

We treated 11 patients with advanced transitional cell carcinoma of upper urinary tract with adjuvant M-VAC chemotherapy and their median survival time was compared with 9 patients without M-VAC chemotherapy as e historical group. The total number of cycles per each patient ranged from 1 to 5 with a mean of 3.4. Of these patients, 8 patients could be evaluated for response and 4 patients were responded (2 complete and 2 incomplete. response rate 50%). The median duration of response was 26 months for complete responders and 4.5 months for incomplete responders. The median duration of survival for all chemotherapy group, complete responders, progression and historical control group were 22, 23+, 14 and 21 months. respectively. Median survival was 22 months in all 11 patients. 23+ months in clinical responders, 14 months in progression and 21 months in historical control group. Although overall survival was not prolonged significantly in chemotherapy than the historical control group, M-VAC was effective in small proportion of patients (CR: 2/8). The duration of survival of the patients with complete remission was prolonged significantly.
Carcinoma, Transitional Cell* ; Doxorubicin* ; Drug Therapy* ; Humans ; Urinary Tract* ; Vinblastine*