1.Revising of belief in a just world scale and its reliability and validity in college students
Zhiqiang SU ; Dajun ZHANG ; Xinqiang WANG
Chinese Journal of Behavioral Medicine and Brain Science 2012;21(6):561-563
ObjectiveTo revise belief in a just world scale (BJW) established by Dalbert according with Chinese cultures and examine its reliability and validity.MethodsAt the base of studying abroad-related questionnaire and preparatory tests,a total 930 undergraduates form The East,The Middle and The West of China participant in this test respectively.ResultsThrough item analysis and explore factor analysis,the revised belief in a just world contained 13 items and 2 subscales which could explain 52.205% of the total variances.The results of confirmatory factor analysis showed that the revised belief in a just world scales had good construct validity.The Cronbach's coefficients of the scales was 0.885,and test-retest reliabilities was 0.884.ConclusionThe revised belief in just world scales has fairly high reliability and validity.
2.Research on the relationship between belief in a just world and prosocial tendencies of college students
Zhiqiang SU ; Dajun ZHANG ; Xinqiang WANG ; Jinliang WANG
Chinese Journal of Behavioral Medicine and Brain Science 2012;21(5):433-435
ObjectiveTo examine the relationship between belief in a just world of college students and prosocial tendencies.Methods400 college students were examined by using the belief in a just of Chinese versions ( BJW ) and the prosocial tendencies scales.Results①There was a marginally significant difference on college student's general belief in a just world and personal belief in a just world among different grades ( F=3.90,F=3.05,P < 0.05 ).②The personal belief in a just world and general belief in a just world was significantly posilively correlated with the prosocial tendencies of college students ( r =0.25,r =0.24,P < 0.01 ).③Significant differences existed between the high-scoriug,the middle group and the low-scoring BJW group in prosocial tendencies and its sub-dimensions ( F =3.36 ~ 12.87,P < 0.05,P < 0.01 ),expect the openness dimension of prosocial tendencies( F =1.71,P > 0.05 ).The scores of those three groups on prosocial tendencies ( (3.74 ± 0.43 ),( 3.57 ± 0.42),( 3.44 ± 0.43 ) ) and its sub-dimensions shows a decreasing trend from high to low.④Layer multivariate linear regression analysis showed that general belief in a just world were significant predictors of the prosocial tendencies( β =0.18,P< 0.01 ).ConclusionsThe intensity of belief in a just world has a certain impact on the prosocial tendencies of college students.
3.Development of coping strategy and gender difference during childhood: a two-year follow-up study
MA Zhengyu, SU Zhiqiang, ZHANG Dajun
Chinese Journal of School Health 2019;40(2):216-220
Objective:
To explore the development trajectory of coping strategy and gender difference during childhood.
Methods:
A total of 355 children in grade 3 from 2 primary schools in Zhongshan of Guangdong Province and Dazhou of Sichuan Province were assessed with cooping strategy and followed up for 2 years.
Results:
Positive and negative coping strategies have different developmental trajectories during childhood, with non-linear upward trend in positive coping strategies (eta11=0.11, 0.02, P>0.05) and non-linear downward trend in negative coping strategies (eta12=-0.70, -0.08, P<0.01). The development of positive coping strategies during childhood showed no significant gender difference (△χ2=5.19, df=4, P>0.05). While the initial average negative coping strategies was significant higher in boys(β=-0.56, P<0.01), and the decreasing velocity was faster than the girls(β=0.33, P<0.01).
Conclusion
The coping strategy during childhood shows great plasticity, with positive and negative coping strategy develops in different trajectory. The developmental trajectories of negative coping strategies during childhood illustrate significant sex difference, while it is not the case for positive coping strategy.
4.Anatomical research of peritrochanteric femur and clinical application of internal fixation for femoral intertrochanteric fractures
Xiao-Yi BAO ; Han-Dong SU ; Wei-Bin LI ; Dajun YING ;
Chinese Journal of Orthopaedic Trauma 2004;0(10):-
Objective To measure the proximal femoral parameters which can provide anatomic evidence for the design of internal fixation components for intertrochanteric fractures of femur.Methods Femoral speci- mens were harvested randomly from 120 healthy adult cadavers(left 60,fight 60).The neck shaft angle,greater trochanter slope length,tilt angle of greater trochanter,axial length of head and neck,lengths of upper and lower borders of the neck,and the minimum transverse diameter of the neck were measured.On the basis of the anatomic study,a two-claw plate was designed to treat 145 cases of femoral intertrochanteric fractures.Results The femoral neck shaft angle was 128.59??6.31?,femoral greater trochanter slope length was(5.5?0.58)cm,tilt angle of femoral greater trochanter was 42.76??5.20?,and axial length of head and neck was(9.42?0.38)cm. There was a correlation between the parameters.All the patients were followed up for a mean time of 23.6 months. The fractures got clinic union in 3 to 6 months.Two cases experienced detachment of claws and hooks but their final outcome was not affected.Three cases suffered coxa vara.All the other cases obtained normal motion function of hips and normal neck shaft angle.No breakage of claw,hook or nail was found in them.Conclusions It is necessary to design an internal fixator that can fit the anatomical features of Chinese femurs in the treatment of intertrochanteric fractures of femur.The two-claw plate designed by us is a good attempt to improve the clinical effect.
5.Application of navigator IDEAL-IQ in liver fat quantification:a comparative study with MRS
Guangbin JIANG ; Bifu HU ; Dajun SU ; Xiao YE ; Chu ZHANG ; Zhiyuan JIAN
Journal of Practical Radiology 2018;34(12):1937-1940,1948
Objective To quantitatively assess the liver fat content by Nav IDEAL-IQ and compare with conventional breath-hold IDEAL-IQ and magnetic resonance spectroscopy (MRS).Methods Twenty volunteers,twenty fatty liver patients and twenty patients with other liver diseases were enrolled in this study.IDEAL-IQ,Nav IDEAL-IQ and MRS imaging were performed and fat fraction (FF) were measured respectively.The results were compared by t-test to explore whether there were differences between these groups. Spearman correlation analysis was also used to test the correlation.Results No significant differences in the FF measured by IDEAL-IQ,Nav IDEAL-IQ and MRS in normal volunteers [(4.09±0.82)%,(3.94±0.83)%,(3.92±0.85)%],fatty liver [(15.5±6.1)%,(11.8±6.5)%,(1 2 .4 ± 7 .2 )% ] and other liver lesions patients [(4.20±0.84)%,(4.00±0.94)%,(3.97±0.96)%]were found between these groups (P>0.05). There was a significant positive correlation between Nav IDEAL-IQ and MRS,and the correlation coefficients of these groups were 0.959,0.786 and 0.945,respectively.Conclusion The results of Nav IDEAL-IQ of fat quantification are consistent with MRS results and it increases the success rate of fat quantitative testing.In a word,it is a noninvasive,convenient and accurate way to measure fat fraction.
6.Improvement mechanism study of kushenol F on ulcerative colitis mice by regulating gut microbiota and immune response
Xudong HE ; Chengzhu SONG ; Haoyu NI ; Yunkai HU ; Min LI ; Dajun CHEN ; Wentao SU ; Jie YU ; Xingxin YANG
China Pharmacy 2024;35(17):2088-2095
OBJECTIVE To explore the action mechanism of kushenol F (KSCF) in treating ulcerative colitis (UC) in mice. METHODS The potential targets of KSCF intervening in UC were predicted with network pharmacology and molecular docking. C57BL/6J mice were randomly divided by body weight into model group, positive control group (sulfasalazine, 703 mg/kg), KSCF group (100 mg/kg), and normal group, with 6 mice per group. The UC model of mice was induced by dextran sulfate sodium solution. During the modeling period, the mice were given relevant medicine intragastrically, once a day, for 7 consecutive days. After the last administration, the disease activity index (DAI) of the mice was scored; the length of the mice’s colon was measured; pathological changes in the colon tissue of mice were observed; the levels of lipopolysaccharide (LPS) in serum, myeloperoxidase (MPO), nitric oxide (NO) and superoxide dismutase (SOD) in the colon were detected in mice; the expression levels of occludin and ZO-1 in colon tissue of mice were detected; the proportions of CD3+T, CD4+T, and CD8+T lymphocytes in the spleen and the ratio of CD4+/CD8+ were detected; changes in colonic microbiota were analyzed by 16S rDNA sequencing. RESULTS Results of network pharmacology indicated that KSCF may treat UC by regulating signaling pathways such as phosphatidylinositol-3 kinase/protein kinase B (PI3K/AKT) and nuclear factor kappa B (NF- κB). Molecular docking results showed that KSCF bound most stably with NF-κB p65 protein. Animal experiment results demonstrated that, compared with the model group, the pathological characteristics of colon tissue in mice were improved in KSCF group. DAI scores, serum levels of LPS, the levels of MPO,NF-κB p65 phosphorylation and NLRP3 protein expression in the colon, and the proportion of CD8+T lymphocytes in the spleen were reduced significantly (P<0.05). Body weight, SOD levels, expression levels of occludin and ZO-1 in the colon, proportions of CD3+T and CD4+T lymphocytes, and the CD4+/CD8+ ratio in the spleen were significantly increased (P<0.05); the abundance of Firmicutes, Actinobacteria, Akkermansia, and Lactobacillus genera were increased, while Proteobacteria decreased; the microbial community structure tended towards that of the normal group. CONCLUSIONS KSCF alleviates UC by restoring intestinal microbial imbalance, enhancing immune response, and inhibiting colonic inflammatory responses, thereby improving intestinal barrier integrity.