Objective:To establish a stable animal model of acute cerebral venous occlusion and to evaluate the model with DWI,PWI,MRS and DTI in observing the changing regularity of the brain parenchymal lesions.Methods:Thirty cats were randomly divided into 2 groups,operation group(n=24) and sham operation group(n=6).Operation group was performed by injection of the cellulose acetate polymer(CAP) solution into the superior sagittal sinus(SSS) to establish the acute cerebral venous occlusion,while sham operation group underwent only the exposure of SSS.MRI was performed at 1,3,6,12,24 and 48h after operation.Results:Twenty-two cats in operation group were operated successfully.Twenty-five lesions were detected on DWI in 14 cats.Thirty-one abnormal perfusion regions were detected on PWI in 17 cats.MRS showed that Lac increased obviously in 1h after operation and decreased gradually later,and NAA decreased in 3h.DTI showed that ADCav values decreased in 1h,increased 3h later and FA values decreased at all time points after operation.The microscopic changes were mainly vasogenic edema and followed by venous cerebral infarction and cerebral hemorrhage in 12h.No abnormal findings were observed in sham operation group.Conclusion:Establishment of acute cerebral venous occlusion model by injection of CAP solution into SSS is feasible.The model is suitable for pathophysiological and radiological studies.DWI combined PWI,MRS and DTI have great value in judging the dynamic changes and the etiopathogenesis of brain parenchymal lesions in acute cerebral venous occlusion.

This article utilizes the latest digitization development trend of medical imaging teaching to illustrate the value of digitization in medical imaging, which discusses the setting up meaning, establishing methods, management and application, etc. of digital teaching data base.

Objective To investigate the clinical values and influencing factors of1H magnetic resonance spectroscopy(1H-MRS) in breast tumors.Methods Thirty-eight patients with breast tumors confirmed pathologically,including 20 cases of breast cancers and 18 cases of benign tumors examined by dynamic contrast-enhanced MRI and1H-MRS were studied retrospectively in comparison with pathology.The value of1H-MRS in detecting breast cancers was evaluated.Results On1H-MRS,11 breast cancers had increased choline peaks and 3 benign tumors presented increased choline peaks.The sensitivity,specificity and accuracy were 55.0%,83.3%and 68.4% respectively by using choline peak to detect breast cancers.Conclusion 1H-MRS has high diagnostic specificity for breast cancer.The low sensitivity of Choline to be detected rate in breast cancer is mainly dues to the lesions and technique factors.

This article discussed the problems in teaching medical imaging from such aspects as teaching contents,methods,conditions and teacher cultivation on the basis of our teaching practice.

Objective To evaluate the value of 320 row CT upper abdominal computed tomography angiography (CTA) in the follow up of transjugular intrahepatic portosystemic shunt(TIPSS) .Methods 21 cases after TIPSS therapy underwent upper ab-dominal CTA .Post-processing images ,including MPR ,VR ,MIP ,and CPR ,were used to determine the position and patency of the stent .The best images of the portal veins were obtained .Results Among the 21 cases ,CPR image clearly demonstrated endovascu-lar stent thrombosis in 3 cases(14 .29% ) with stent occlusion and 1 case(4 .76% ) with stent stenosis ;there were no stent stenosis or occlusion in 17 cases(80 .95% ) ,their CPR image showed the contrast agent was filled completely in the stent and no low-density thrombosis was found .The best phase of the portal vein was 45 s .Conclusion 320 row CT upper abdominal CTA can clearly dis-play the stent position and patency situation in patients ,therefore ,should be regarded as the first choice for the follow-up of patients after TIPSS therapy .

In view of the problems existing in medical image network teaching, such as redundant and rigid curriculum system, obsolete structure, untimely updates, lack of supervision system and poor stability of network security and so on, we explored how to improve the medical image network teaching from the fusion of traditional teaching, optimizing curriculum system, perfecting the medical imaging system of autonomous learning, encouraging online communication, creating a good atmosphere, increasing invest-ment in software development and multi-sectoral collaboration, in order to complete the transfer of knowl-edge more effectively, and promote the good development of medical imaging teaching.

Objective To evaluate the reproducibility and agreement in the measurement of liver volume with multi-slice spiral computed tomography(CT).Methods Spiral CT was performed in 20 cases(14 healthy volunteers and 6 patients with cirrhosis).Images were transferred to a workstation,and volumes were measured by three observers with 5-year abdominal CT experience.Each observer performed the measurements in all subjects twice.Intra-observer and inter-observer variability was calculated using analysis of variance of the repeatedly measured results.The agreement was analyzed with the intra-class correlation coefficient(ICC).Reliability analysis in inter-observer was performed with Cronbach's alpha coefficient.Results Data measured by Observer A were(1 265.53?421.43)cm3 and(1 272.30?414.73)cm3 [difference:(0.80?2.20)%,P=0.15,ICC=0.998 8],Observer B(1 299.97?403.48)cm3 and(1 310.23?404.04)cm3 [difference:(0.90?1.90)%,P=0.07,ICC=0.998 3],Observer C(1 282.18?425.91)cm3 and(1 289.73?424.66)cm3 [difference:(0.70?2.60)%,P=0.19,ICC=0.998 3],respectively.The mean liver volumes by the three observers were(1 268.91?418.07)cm3,(1 305.10?403.59)cm3,and(1 285.97?425.10)cm3,respectively(P=0.07,ICC=0.986 9,Cronbach's alpha coefficient=0.995 6).Conclusion High reproducibility and agreement in the measurement of liver volume can be achieved with multi-slice spiral CT.

It has been a general trend to open the 5+3 medical personnel training mode of radiology in China.But at present,there are still a lot of problems during the process,such as,lack of training plan,unified teaching materials and examination index for reference,lack of learning consciousness and self-discipline among the students who participate in the standardization training,lack of adequate teaching resources in the standardization training base,and so on.In order to cultivate qualified and high-quality radiologists,this paper discussed the ways of forming a new set mode of 5+3 medical personnel training in the radiology department through exploration and practice,including strengthening teachers' construction and building a professional teachers troop,reforming the teaching method of standardization training,improving the teaching base infrastructure,establishing and perfecting the assessment evaluation mechanism.

OBJECTIVETo study the effectiveness of the granules of eliminating phlegm and removing blood stasis (GEPRB) on glucose metabolism for diabetic rats induced by streptozotocin and that on early diabetic rats cochlear histopathology.

METHODIntraperitoneally inject streptozotocin disposable of dose of 55 mg x kg(-1), so that a model of diabetic rats is created, and treated by, and simultaneously treated by Duxil as matched groups for positive, then observe the blood glucose of each group, the histopathology of cochlear, and any circumstantial change of their microstructures.

RESULTGEPRB can reduce the cumulating thickness of the basilar membrane and that of the vascular pattern, so as to tighten up the sparsity of the spiral ganglion cells.

CONCLUSIONGEPRB is rather effective on hypoglycemic for the diabetic rat model, and therapeutic goal can be achieved by improving the pathological changes of the cochlea damaged. The improvement by GEPRB for microangiopathic change of the cochlea capillary is probably the pathological basis of relieving hearing loss.

Animals ; Cochlea ; anatomy & histology ; blood supply ; drug effects ; Diabetes Complications ; drug therapy ; Disease Models, Animal ; Dosage Forms ; Drugs, Chinese Herbal ; administration & dosage ; Ear Diseases ; drug therapy ; Humans ; Male ; Rats ; Rats, Sprague-Dawley

Objective To investigate the differential diagnostic value of computed tomography (CT) combined with serum tumor markers in borderline ovarian tumors (BOT) and benign epithelial ovarian tumors (BET).Methods The CT data in 28 patients with BOT and 41 patients with BET,both confirmed by surgery and pathological,were analyzed retrospectively.Their preoperative serum carbohydrate antigen 125 (CA125),human epididymis secretory protein 4 (HE4) and carcinoembryonic antigen (CEA) detection results were collected.The CT images features and serum tumor markers levels were compared between the two groups.Results The difference in the appearance rate of tumor solid composition,thick septum and wall nodule between the two groups had statistical significance (x2 =25.135,5.240,5.066,P＜0.05).The serum CA125 level had statistical difference between the two groups (Z=3.202,P＜0.05),while serum HE4 and CEA levels had no statistically significant difference between the two groups(Z=0.330,1.122,P＞0.05).The optimal critical value,sensitivity and specificity of serum CA125 level in differential diagnosis of two kinds of tumor was 42.45 U/mL,53.6％ and 85.4％.The overall diagnostic rate of solid composition and thick septum for diagnosing the two kinds of tumor was 78.5 ％.The overall diagnostic rate of solid composition,thick septum and CA125 level for diagnosing the two kinds of tumor was 81.2％.Conclusion The appearance of solid composition,thick septum and serum CA125 level increase in epithelial ovarian tumor may help to identify BOT and BET.