1.Effect of romosozumab in premenopausal women with severe osteoporosis and anorexia nervosa
Kazuki FUJIMOTO ; Narumi MAKI ; Daisuke HASHIBA ; Toshifumi MAEYAMA ; Ryosuke NAKAGAWA ; Hajime ARAI ; Seiji OHTORI
Osteoporosis and Sarcopenia 2023;9(4):137-141
Objectives:
This study aims to investigate the effects of romosozumab on bone mineral density (BMD) and bone metabolism.
Methods:
In this retrospective case series, romosozumab was administered to 5 premenopausal female patients with osteoporosis and anorexia nervosa with fragility fractures. BMD and bone turnover marker changes were investigated at 6 months and 1 year after administering romosozumab.
Results:
BMD increased and high-turnover bone metabolism decreased 6 months and 1 year after administering romosozumab.
Conclusions
Romosozumab is useful for treating osteoporosis in patients with anorexia nervosa.
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