The sunlight protecting effect of indomethacin (IM) was compared with topical sun screening agents of sun protecting factor(SPF) 2 and SPF 4, and it was found that IM stood in between SPF 2 and SPF 4. (vehicle of IM) painted skin was 4.8 J/cm and MED skin was 37.5 m J/cm. with UVB of PED painted was compared with topical 2 and SPF 4, and it was MED with UVA of PED with UVB of PED painted skin was 37 5 m J/cm.
Indomethacin* ; Mass Screening ; Paint ; Skin ; Solar System ; Sunlight

The following facts have been identified as a result of epidemiogical trend and characteristic of Japanese Encephalitis in Korea for the last 20 years. First: The Epidemiological period which was ten-year and three-year in the past has been disappeared following the start of immunization program at 1970. Second: The incidence rate was much higher in the south and West areas than northeast area of Korea. City and province with the highest incidence rate was Chungcheong Nam Province and Cholla Buk Province. Third: Regardless of scope of prevalence, the main season that 90 percent of total incidence occurs in one month from mid-September. Fourth: The number of case by age was that 80 percent of total patients is children aged 3-15. Recently there is an increase in the number of patients who are elderly people. Fifth: The study on the ecological conditions of mosquito including wintering and effectiveness of immunization for Japanese Encephalitis and duration on antibody should be done. Sixth: There has been no case of Japanese Encephalitis during last three years since 1984 mainly due to disinfecting to eradicate mosquitos, immunization for vulnerable group of people aged 3-15, individual precaution not to be bitten by mosquito, improvement sanitation. While there has been no case of Japanese Encephalitis during last three years, there is possibility that Japanese Encephalitis becomes prevalent again anytime since its virus has been isolated continuously from the natural reservoirs.
Aged ; Asian Continental Ancestry Group* ; Child ; Culicidae ; Encephalitis, Japanese* ; Humans ; Immunization ; Immunization Programs ; Incidence ; Korea* ; Prevalence ; Sanitation ; Seasons

Basal cell carcinomas(BCCs) are usually treated with ablative proccdures, but a nonsurgical treatment would conserve tissue and obtain a better cosmetic out come as well as treat patients who refuse surgery or those who are not good surgical candidates. Because of inadequate drug penetration, low cure rates, high recurence rates, and adverse reactions, such as contact dermatitis, topical 5-fluorouracil(5-FU) is unsaitble to treat nodular BCCs. But, int,ralesional 5-FU has been reported to be effective for nodular BCCs. The efficacy and safety of intralesional injection of 5-FU have been evaluated for treatment of BCCs. The results revealed that intralesional injection of 5-FU seems to be effective in the treatment of various premalignant and malignant skin lesions as well as BCCs without side effects.
Carcinoma, Basal Cell* ; Dermatitis, Contact ; Fluorouracil* ; Humans ; Injections, Intralesional* ; Skin

We report a case of lupus vulgaris following BCG vaccination in a 12-year-old male. The patient was vaccinated against tuberculosis on right shoulder 6 months ago. The erythemstous papular eruptions began to develop on the BCG vaccinated site 2 weeks after vaccination. The eruptions progressed to be pruritic, erythematous plaque which was flat, crescent shaped, and centrally covered by adherent scales for 6 months. Histopathological findings revealed tubercles and tuberculoid structures composed of epitheloid cells and Langhans giant, cells in the dermis. Caseation necrosis within the tubercles was slight or absent. In addition, there was an infiltrate of mononuclear cells around the tubercles. The skin lesions cleared after 6 months of treatment with oral isoniazid 300mg daily.
Child ; Dermis ; Humans ; Isoniazid ; Lupus Vulgaris* ; Male ; Mycobacterium bovis* ; Necrosis ; Shoulder ; Skin ; Tuberculosis ; Vaccination* ; Weights and Measures

No abstract available.
Neurofibroma ; Neurofibromatoses ; Neurofibromatosis 1

No abstract available.
Chin* ; Polyps* ; Skin*

No abstract available.
Nevus, Epithelioid and Spindle Cell*

BACKGROUND: Recent studies have shown an incomplete agreement with the previously proposed diagnostic criteria of Hanifin and Rajka for atopic dermatitis(AD). This could be due to ethnic differences in the clinical manifestations of AD. To make a diagnosis of AD with confidence, one has to depend on the history and clinical picture according to race. OBJECTIVES: The purpose of the present study was to find out the importance of individual symptoms and histories for the diagnosis of Korean AD by questionnaire. METHODS: The frequency of 25 questionnaire items was studied in 130 patients with typical AD (48 childhood, 82 adolescence/adult) compared to that in 198 control subjects (89 childhood, 109 adolescence/adult). RESULTS: Nine items(itchy with bodily heat, itchy when sweating, cholinergic urticaria, miliaria, irritation with fabrics, food reaction, pollen allergy, itch with stress) were shown to be of much diagnostic significance(p<0.001) in childhood AD,otherwise thirteen items(itchy with bodily heat, itchy when sweating, cholinergic urticaria, sense of fever, excessive sweating, miliaria, irritation with cosmetics, irritation with fabrics, irritation prone hands, itchy with woolen clothes, pollen allergy, itch with stress, dermographism) were in adolescent and adult, AD. CONCLUSION: We found some diagnostic significance of clinical histories in Korean AD patients by questionnaire. We propose that this accessible questionnaire would be an efficient and powerful method with which to obtain new and valid information on AD.
Adolescent ; Adult ; Continental Population Groups ; Dermatitis, Atopic* ; Diagnosis ; Fever ; Hand ; Hot Temperature ; Humans ; Miliaria ; Surveys and Questionnaires ; Rhinitis, Allergic, Seasonal ; Sweat ; Sweating ; Urticaria

Fibrous papule of the face occurs nearly always as a solitary lesion on the face, especially on the nose. The lesion which appears as a dome shaped papule, is skin colored, pigmented or red, We present herein three cases of fibrous papule of the face, which developed on the ala nasi of 45-year-old man, and 49-year-old woman, and on the nostrile of 25-year-old woman. Histopathologic findings showed dermal angiofibrotic changes in two cases. In one of the two cases, there were atypical cells with large irregular nucleus and a few multinucleated giant cells interspersed in the edematous dermis, and there was distinct perifollicular fibrosis in the other case.
Adult ; Dermis ; Female ; Fibrosis ; Giant Cells ; Humans ; Middle Aged ; Nose ; Skin

We report herein a case of bowenoid papulosis, which developed on the groin, the shaft of the penis and left parietal area, of scalp in a 31-year-old male. Clinical features present as brown to brown-black papules and verrucous plaques ranging from 2 cm to 12 cm in diameter. Electron microscopic examination of the specimen obtained from our patient fail to reveal viral particles.
Adult ; Genitalia* ; Groin ; Humans ; Male ; Penis ; Rabeprazole ; Scalp ; Virion