1.Thoracic Myelopathy and Radiculomyelopathy due to Ossification of the Ligamentum Flavum: A Cases Report.
Sang Dae LEE ; Dong Youl RHEE ; Young Gyun JEONG ; Hyuck PARK ; Bong Soo CHO ; Soo Young KIM
Journal of Korean Neurosurgical Society 2000;29(10):1377-1382
No abstract available.
Ligamentum Flavum*
;
Spinal Cord Diseases*
2.A Case Report of Gastric Dilatation.
Youn Shin KIM ; Ho LEE ; Yu Kyoung JUNG ; Dae Youl KIM ; Il Hoon KWON
Korean Journal of Legal Medicine 1999;23(2):107-110
Gastric dilatation is a rare life-threatening condition and consists of massive distention of the stomach by gas and fluid. Its etiology is unclear but predisposing factors include recent surgery, diabetic gastroparesis, fundoplication and gastric outlet obstruction. As the distended stomach grows larger, it hangs down across the duodenum, producing a mechanical gastric outlet obstruction, venous obstruction of the mucosa, ischemic necrosis and perforation. The distended stomach pushes the diaphragm upward, causing collapse of the left lung, rotation of the heart, and obstruction of the inferior vena cava. Hypochloremia, hypokalemia, and alkalosis may result from fluid and electrolyte losses and may precipitate cardiac arrhythmias. If acute gastric dilatation is not treated promptly, cardiovascular and pulmonary compromise may compound an increasing intravascular volume deficit leading to hypotension, which may be a cause of death.
Alkalosis
;
Arrhythmias, Cardiac
;
Causality
;
Cause of Death
;
Diaphragm
;
Duodenum
;
Fundoplication
;
Gastric Dilatation*
;
Gastric Outlet Obstruction
;
Gastroparesis
;
Heart
;
Hypokalemia
;
Hypotension
;
Lung
;
Mucous Membrane
;
Necrosis
;
Stomach
;
Vena Cava, Inferior
3.A Case Report of Gastric Dilatation.
Youn Shin KIM ; Ho LEE ; Yu Kyoung JUNG ; Dae Youl KIM ; Il Hoon KWON
Korean Journal of Legal Medicine 1999;23(2):107-110
Gastric dilatation is a rare life-threatening condition and consists of massive distention of the stomach by gas and fluid. Its etiology is unclear but predisposing factors include recent surgery, diabetic gastroparesis, fundoplication and gastric outlet obstruction. As the distended stomach grows larger, it hangs down across the duodenum, producing a mechanical gastric outlet obstruction, venous obstruction of the mucosa, ischemic necrosis and perforation. The distended stomach pushes the diaphragm upward, causing collapse of the left lung, rotation of the heart, and obstruction of the inferior vena cava. Hypochloremia, hypokalemia, and alkalosis may result from fluid and electrolyte losses and may precipitate cardiac arrhythmias. If acute gastric dilatation is not treated promptly, cardiovascular and pulmonary compromise may compound an increasing intravascular volume deficit leading to hypotension, which may be a cause of death.
Alkalosis
;
Arrhythmias, Cardiac
;
Causality
;
Cause of Death
;
Diaphragm
;
Duodenum
;
Fundoplication
;
Gastric Dilatation*
;
Gastric Outlet Obstruction
;
Gastroparesis
;
Heart
;
Hypokalemia
;
Hypotension
;
Lung
;
Mucous Membrane
;
Necrosis
;
Stomach
;
Vena Cava, Inferior
4.The Availability of Allogenic Fibular Bone Graft with Autogenous Bone Dust in Anterior Cervical Fusion after Cervical Discectomy.
Sang Dae LEE ; Soo Young KIM ; Young Gyun JEONG ; Bong Soo CHO ; Hyuck PARK ; Dong Youl RHEE
Journal of Korean Neurosurgical Society 2000;29(8):1043-1049
No abstract available.
Diskectomy*
;
Dust*
;
Transplants*
5.A Case of Bullous Systemic Lupus Erythematosus:Clustered Tense Bullae Localized on the Face.
Joon Hong PARK ; Jung Youl LEE ; Hee Dae JEON ; Hye Jin LEE ; Dae Sik HONG ; Hee Sook PARK ; Kyu Uang WHANG
Annals of Dermatology 1999;11(2):82-85
A 21-year-old woman, who had a one-year history of pancytopenia with histiocytic necrotizing lymphadenitis and hepatosplenomegaly, presented with a 5 day history of tense bullae, which were localized on the face. These clusters of tense bullae occurred on clinically normal skin, she did not have other skin lesions. A diagnosis of bullous systemic lupus erythematosus (BSLE) was established based on clinical, laboratory, histological, and immunological findings. The bullae showed good responses to dapsone (100mg, daily) and resolved within 10 days with-out scaring. Bullous lesions of SLE may be the first cutaneous manifestation in some patients with SLE and should be considered in the differential diagnosis of the other subepidermal bullous disorders.
Blister
;
Dapsone
;
Diagnosis
;
Diagnosis, Differential
;
Female
;
Histiocytic Necrotizing Lymphadenitis
;
Humans
;
Lupus Erythematosus, Systemic
;
Pancytopenia
;
Skin
;
Transcutaneous Electric Nerve Stimulation*
;
Young Adult
6.Effects of a DPP-4 Inhibitor and RAS Blockade on Clinical Outcomes of Patients with Diabetes and COVID-19
Sang Youl RHEE ; Jeongwoo LEE ; Hyewon NAM ; Dae-Sung KYOUNG ; Dong Wook SHIN ; Dae Jung KIM
Diabetes & Metabolism Journal 2021;45(2):251-259
Background:
Dipeptidyl peptidase-4 inhibitor (DPP-4i) and renin-angiotensin system (RAS) blockade are reported to affect the clinical course of coronavirus disease 2019 (COVID-19) in patients with diabetes mellitus (DM).
Methods:
As of May 2020, analysis was conducted on all subjects who could confirm their history of claims related to COVID-19 in the National Health Insurance Review and Assessment Service (HIRA) database in Korea. Using this dataset, we compared the short-term prognosis of COVID-19 infection according to the use of DPP-4i and RAS blockade. Additionally, we validated the results using the National Health Insurance Service (NHIS) of Korea dataset.
Results:
Totally, data of 67,850 subjects were accessible in the HIRA dataset. Of these, 5,080 were confirmed COVID-19. Among these, 832 subjects with DM were selected for analysis in this study. Among the subjects, 263 (31.6%) and 327 (39.3%) were DPP4i and RAS blockade users, respectively. Thirty-four subjects (4.09%) received intensive care or died. The adjusted odds ratio for severe treatment among DPP-4i users was 0.362 (95% confidence interval [CI], 0.135 to 0.971), and that for RAS blockade users was 0.599 (95% CI, 0.251 to 1.431). These findings were consistent with the analysis based on the NHIS data using 704 final subjects. The adjusted odds ratio for severe treatment among DPP-4i users was 0.303 (95% CI, 0.135 to 0.682), and that for RAS blockade users was 0.811 (95% CI, 0.391 to 1.682).
Conclusion
This study suggests that DPP-4i is significantly associated with a better clinical outcome of patients with COVID-19.
7.Effects of a DPP-4 Inhibitor and RAS Blockade on Clinical Outcomes of Patients with Diabetes and COVID-19
Sang Youl RHEE ; Jeongwoo LEE ; Hyewon NAM ; Dae-Sung KYOUNG ; Dong Wook SHIN ; Dae Jung KIM
Diabetes & Metabolism Journal 2021;45(2):251-259
Background:
Dipeptidyl peptidase-4 inhibitor (DPP-4i) and renin-angiotensin system (RAS) blockade are reported to affect the clinical course of coronavirus disease 2019 (COVID-19) in patients with diabetes mellitus (DM).
Methods:
As of May 2020, analysis was conducted on all subjects who could confirm their history of claims related to COVID-19 in the National Health Insurance Review and Assessment Service (HIRA) database in Korea. Using this dataset, we compared the short-term prognosis of COVID-19 infection according to the use of DPP-4i and RAS blockade. Additionally, we validated the results using the National Health Insurance Service (NHIS) of Korea dataset.
Results:
Totally, data of 67,850 subjects were accessible in the HIRA dataset. Of these, 5,080 were confirmed COVID-19. Among these, 832 subjects with DM were selected for analysis in this study. Among the subjects, 263 (31.6%) and 327 (39.3%) were DPP4i and RAS blockade users, respectively. Thirty-four subjects (4.09%) received intensive care or died. The adjusted odds ratio for severe treatment among DPP-4i users was 0.362 (95% confidence interval [CI], 0.135 to 0.971), and that for RAS blockade users was 0.599 (95% CI, 0.251 to 1.431). These findings were consistent with the analysis based on the NHIS data using 704 final subjects. The adjusted odds ratio for severe treatment among DPP-4i users was 0.303 (95% CI, 0.135 to 0.682), and that for RAS blockade users was 0.811 (95% CI, 0.391 to 1.682).
Conclusion
This study suggests that DPP-4i is significantly associated with a better clinical outcome of patients with COVID-19.
8.A Case of Microscopic Polyangitis Presented as Pulmonary Hemorrhage and Rapidly Progressive Glomerulonephritis.
Jae Eun LEE ; Young Sook CHAE ; Oh Keyng LEE ; Dae Youl LEE
Journal of the Korean Pediatric Society 1999;42(2):274-278
Microscopic polyangitis(MPA) is defined as a systemic necrotizing vasculitis that affects small-sized vessels without granulomata. MPA is associated with focal segmental necrotizing glomerulonephritis. Clinical manifestations are similar to those of polyarteritis nodosa, but are characterized by the presence of rapidly progressive glomerulonephritis and pulmonary involvement, including pulmonary hemorrhage. We reported a case of microscopic polyangitis presenting pulmonary hemorrhage and rapidly progressive glomerulonephritis with a brief review of literatures.
Glomerulonephritis*
;
Hemorrhage*
;
Polyarteritis Nodosa
;
Vasculitis
9.Efficacy of Bicalutamide Monotherapy in Locally Advanced Prostate Cancer.
Jun Sung KOH ; Chung Bum LEE ; Hong Jin SUH ; Yoon Bo LEE ; Dae Haeng CHO ; Ji Youl LEE
Korean Journal of Urology 2004;45(2):108-113
PURPOSE: Nonsteroidal antiandrogen monotherapy may be a treatment option for some patients with locally advanced prostate cancer. We report the efficacy, advantage, and adverse events of bicalutamide monotherapy in patients with locally advanced prostate cancer. MATERIALS AND METHODS: We retrospectively reviewed 13 patients with locally advanced prostate cancer who were treated with bicalutamide 150mg monotherapy. Serum PSA reduction was evaluated with periodic PSA follow-ups. If clinical progression was suspected, pelvic CT or bone scan was performed for the evaluation of disease progression. The changes of sexual function were assessed with the IIEF questionnaires prior to treatment and after 6 months of medication. RESULTS: Serum PSA declined to less than 2ng/ml within 3 months after treatment in most patients. A high serum PSA level was maintained in only 1 patient, and this patient showed disease progression. There were no significant differences between the mean scores of the pretreatment and post-treatment erectile function, orgasmic function, sexual desire, intercourse satisfaction, and overall satisfaction (p>0.05). Of the 13 patients, 2 patients (15.5%) showed adverse events, such as breast pain and gynecomastia. However, the symptoms were mild to moderate. There was no withdrawal to medication due to drug-related adverse events. CONCLUSIONS: From the viewpoint of the fall in serum PSA levels after 3 months, bicalutamide monotherapy was effective in the treatment of locally advanced prostate cancer. There were benefits to the patients in terms of the quality of life parameters, sexual function, and tolerability, which make bicalutamide monotherapy an attractive treatment option for patients with locally advanced prostate cancer. (Korean J Urol 2004;45: 108-113)
Disease Progression
;
Follow-Up Studies
;
Gynecomastia
;
Humans
;
Male
;
Mastodynia
;
Orgasm
;
Prostate*
;
Prostatic Neoplasms*
;
Quality of Life
;
Surveys and Questionnaires
;
Retrospective Studies
10.Assessment of Quality of Life after Cystectomy: Comparison of Orthotopic Neobladder Versus Ileal Conduit.
Sae Woong KIM ; Ji Youl LEE ; Seung Ju LEE ; Jae Sung HA ; Chung Bum LEE ; Yong Hyun CHO ; Dae Hang CHO ; Moon Soo YOON
Korean Journal of Urology 2000;41(7):819-825
No abstract available.
Cystectomy*
;
Quality of Life*
;
Urinary Diversion*