No abstract available.
Hematology* ; Humans ; Thyroid Gland*

To evaluate the risk and factors associated with seizure recurrence in children with epilepsy while receiving the adequate anticonvulsant treament, we studied 58 patients with newly diagnosed epilepsy who were followed prospectively for a median of 26 months (range 7 to 54). The results were as follows: 1) Forty-four of the 58 patients (75.9%) had recurrence of seizure. 2) The rate of recurrence according to type of seizure was observed to be 22 patients (68.8%) in generalized tonic-clonic seizure, 6 patients (85.7%) in simple partial seizure, 5 patients (83.3%) in complex partial seizure, 3 patients (100%) in mixed seizure, 2 patients (100%) in absence, 3 patients (100%) in infantile spasm, 1 patient (100%) in atonic seizure, 2 patients (50%) in secondary generalized seizure. There was no significant difference in the risk of recurrence observed among these seizure types. 3) The risk of recurrence varied according to the history of seizure, seizure recurrence was observed in 100% of the cases with history of neonatal seizure, 72.7% of the cases with febrile convulsion, and 73.3% of the cases with non-specific history. No significant difference was observed among these past history of seizure. 4) The rate of seizure recurrence according to electroencephalographic abnormalities did not differ significantly. Seizure recurrence was noted in 13 of the 18 patients with mildly disordered tracings (72.2%), 15 of the 20 patients with moderate abnormality (75.0%), and 12 of the 16 patients with severe abnormality (75.0%). 5) Recurrence rate according to cause of seizure was more significantly frequent in those with symptomatic epilepsy than in those with idiopathic type (100% vs 70.2%, p<0.05). 6) The frequency percentage of seizure recurrence by age groups of below 1 year, 1 to 3 years, 4 to 6 years, and above 6 years at onset of seizure were 100, 66.7, 57.1, and 72.7, respectively. The rate of seizure recurrence was significantly highest in patients aged below 1 year at onset of seizure. 7) There was significant difference in seizure recurrence between those with and without abnormalities as shown by neurologic examination (100% vs 70.8%, p<0.05). 8) There was no consistent difference in valproic acid serum levels between those who had a recurrence and those who did not. The patients receiving phenobarbital had significantly high serum levels of the phenobarbital in recurrent groups than those who had no recurrence. In conclusion, factors associated with an increased risk of seizure recurrence were early age at onset of epilepsy, symptomatic epilepsy, and neurologic abnormalities. We found no associations between risks of recurrence and types of epilepsy, or electroencephalographic abnormalities.
Anticonvulsants* ; Child ; Epilepsy ; Humans ; Infant ; Infant, Newborn ; Neurologic Examination ; Phenobarbital ; Prospective Studies ; Recurrence* ; Risk Factors ; Seizures* ; Seizures, Febrile ; Spasms, Infantile ; Valproic Acid

BACKGROUND: Dense breast reduced the sensitivity of mammography in breast cancer screening and known as an independent risk factor of breast cancer. The relationship between breast density and age, body mass index has studied. However, there are few studies on the relationship between breast density and lifestyle related disease. In this study, we investigated the relationship between mammographic breast density and lifestyle related disease. METHODS: Retrospective cross sectional research was carried out from people who visited a single health screening center in Busan from January 2015 to December 2015. We investigated age, past history of the subjects and measured their height, weight, blood pressure and waist circumference. The biochemical test was carried out using their blood. All patients underwent mammography. The breast density on mammography determined by the basis of American College of Radiology Breast Imaging Reporting and Data System (ACR BI-RADS) breast composition and 996 people was recruited. RESULTS: In the distribution of breast density, 16.3% of women (n=160) had dense breast. Age (under 49), body mass index (BMI) (underweight) were positively correlated with the BI-RADS composition category 3, 4 but the number of lifestyle related disease were negatively correlated (age ρ=0.17, BMI ρ=0.39, the number of lifestyle related disease ρ=-0.21). The odds ratio (OR) of dense breast increased with decreasing lifestyle related disease severity (OR=3.06, 95% confidence interval: 1.13-8.22, P=0.027). CONCLUSIONS: This study showed that the number of lifestyle related disease was negatively correlated with mammographic density. The OR of dense breast increased with decreasing lifestyle related disease severity. Therefore, primary physicians should consider negative correlation between breast density and lifestyle related disease in breast cancer screening.
Blood Pressure ; Body Mass Index ; Breast Neoplasms ; Breast* ; Busan ; Female ; Humans ; Information Systems ; Life Style* ; Mammography* ; Mass Screening ; Odds Ratio ; Retrospective Studies ; Risk Factors ; Waist Circumference

This study was conducted to provide basic data on physiological and hematological characteristics, and organ weights of beagle dogs. A total of 237 beagle dogs were used to determine differences in physiological and hematological parameters, and organ weights depending on sex and age. The respiratory rate of both sexes tended to increase as they grew older and the female heart rate was slightly higher than that of males. Male and female body weights increased rapidly to 33 weeks old followed by a gradual increase to 41-weeks-old. The relative weight of the brain was negatively correlated with body weight, whereas the weight of reproductive organs was positively correlated with body weight. The platelet count of female dogs was slightly higher than that of males. The red blood cell, hemoglobin, and hematocrit of both sexes increased non-significantly with age. In the leukocyte differential count, the neutrophils, and eosinophils of both sexes tended to increase as they grew older, whereas basophils, lymphocytes, and monocytes decreased. In the serum biochemical profiles, alkaline phosphatase was slightly higher in males than females, while the total cholesterol of female dogs at 9-months-old was higher than that of males at the same age. Other biochemical components, including alanine aminotransferase, blood urea nitrogen, creatinine, triglyceride, and total protein increased non-significantly with age in both sexes. To conclude, we observe no significant physiological or hematological differences with sex or age, although decreasing and increasing trends were detected with some parameters. These data provide valuable reference indices of the normal physiological and hematological characteristics of beagle dogs, which should prove useful in toxicological and pharmacological studies.
Alanine Transaminase ; Alkaline Phosphatase ; Animals ; Basophils ; Biochemistry ; Blood Urea Nitrogen ; Body Weight ; Brain ; Cholesterol ; Creatinine ; Dogs ; Eosinophils ; Erythrocytes ; Female ; Heart Rate ; Hematocrit ; Hematology ; Hemoglobins ; Humans ; Leukocytes ; Lymphocytes ; Male ; Monocytes ; Neutrophils ; Organ Size ; Platelet Count ; Respiratory Rate ; Urology

Extremities ; Femoral Artery ; Forearm ; Free Tissue Flaps ; Glycosaminoglycans ; Head ; Humans ; Lip ; Neck ; Skin ; Temporal Arteries ; Tissue Donors ; Tongue ; Veins

The presence of pneumocephalus associated with insertion, maintenance, and removal of intravenous catheters is a rare radiographic finding, but may be clinically relevant. Various pathways have been proposed to explain the development of pneumocephalus, but none are well understood. We present a patient with hemicranial pneumocephalus secondary to removal of a central venous catheter as determined by computed tomography, and we propose a possible mechanism of the pneumocephalus.
Catheterization ; Catheters ; Central Venous Catheters ; Humans ; Pneumocephalus

Primary thyroid lymphoma is a rare tumor which patients usually present an enlarging neck mass, often causing local obstructive symptoms. Hypothyroidism is seen in 30-40% of the patients with primary thyroid lymphoma. We report a 77-year-old man with history of hypothyroidism, presenting enlarging anterior neck mass which pathologically confirmed as thyroid lymphoma with literature review.
Aged ; Dyspnea* ; Humans ; Hypothyroidism ; Lymphoma* ; Neck ; Thyroid Gland*

BACKGROUND: The bispectral index (BIS) has been used as a monitor measuring hypnotic level of anesthesia or sedation. Recently EEG-entropy (M-Entropy(TM), S/5(TM) Entropy Module) has been provided and started to use domestically. This study was designed to compare the measured values between EEG-entropy and BIS monitor on general anesthesia and sedation. METHODS: Thirty patients undergoing total hysterectomy were anesthetized with propofol target controlled infusion (TCI), fentanyl, rocuronium and BIS, RE (response entropy), SE (state entropy), and hemodynamic variables were measured at the effect site concentration of 1.5-10.0 microgram/ml (P15-P100). On the other hand, fifteen patients undergoing breast biopsy were sedated with propfol TCI and BIS, RE and SE were measured at 0.9-2.3 microgram/ml (P09-P23). RESULTS: During general anesthesia, SE values were significantly lower than BIS or RE at baseline. But RE alone at P15, RE and SE at P20 were significantly higher than BIS. During sedation, SE values were significantly lower than BIS or RE at baseline-P09 and significantly lower than RE alone at P10-P15, and RE were significantly higher than BIS at P13-P20. After P21, RE and SE values fell abruptly and approached to BIS. CONCLUSIONS: EEG-entropy reflected hypnotic level well equal to BIS during general anesthesia. However, EEG-entropy did less reflected the hypnotic level than BIS during sedation.
Anesthesia ; Anesthesia, General* ; Biopsy ; Breast ; Entropy ; Fentanyl ; Hand ; Hemodynamics ; Humans ; Hysterectomy ; Propofol

OBJECTIVE: The purpose of this study is to determine the prevalence of sinus disease and abnormalities in patients scheduled for dental implant in maxillary posterior area using cone beam CT. PATIENTS AND METHOD: One hundred five maxillary sinuses in eighty-seven patients who underwent cone beam CT for dental implant in maxillary posterior area were included. Any patients who had previous history of sinus operations were not included. The sinus abnormalities were classified as follows ; normal (membrane thickness <2 mm), mucosal thickening (membrane thickness > or = 2 mm and <6 mm), partial opacification (membrane thickness >6 mm but not full), full opacification and mucous retention cyst. The relationship between the remaining bone height, sinus symptoms and maxillary sinus abnormality was statistically surveyed. RESULTS: Of 105 maxillary sinuses in 87 patients, 80 (76%) maxillary sinuses showed abnormalities ; 4 of 4 symptomatic patients and 76 of 101 asymptomatic patients. Mucosal thickening was the most common sinus abnormality. Only 3 (4%) of 80 maxillary sinus abnormalities were caused by the odontogenic origin. The prevalence of maxillary sinus abnormalities was higher in the symptomatic group than asymptomatic one (p<0.05). CONCLUSION: Maxillary sinus abnormalities were very common in the patients who were planning implantation in maxillary posterior areas. This result supports that thorough evaluation for maxillary sinus is recommended when implant treatment is planned for those areas.
Cone-Beam Computed Tomography ; Dental Implants ; Humans ; Maxillary Sinus ; Prevalence ; Retention (Psychology)

OBJECTIVE: The purpose of this study is to determine the prevalence of sinus disease and abnormalities in patients scheduled for dental implant in maxillary posterior area using cone beam CT. PATIENTS AND METHOD: One hundred five maxillary sinuses in eighty-seven patients who underwent cone beam CT for dental implant in maxillary posterior area were included. Any patients who had previous history of sinus operations were not included. The sinus abnormalities were classified as follows ; normal (membrane thickness <2 mm), mucosal thickening (membrane thickness > or = 2 mm and <6 mm), partial opacification (membrane thickness >6 mm but not full), full opacification and mucous retention cyst. The relationship between the remaining bone height, sinus symptoms and maxillary sinus abnormality was statistically surveyed. RESULTS: Of 105 maxillary sinuses in 87 patients, 80 (76%) maxillary sinuses showed abnormalities ; 4 of 4 symptomatic patients and 76 of 101 asymptomatic patients. Mucosal thickening was the most common sinus abnormality. Only 3 (4%) of 80 maxillary sinus abnormalities were caused by the odontogenic origin. The prevalence of maxillary sinus abnormalities was higher in the symptomatic group than asymptomatic one (p<0.05). CONCLUSION: Maxillary sinus abnormalities were very common in the patients who were planning implantation in maxillary posterior areas. This result supports that thorough evaluation for maxillary sinus is recommended when implant treatment is planned for those areas.
Cone-Beam Computed Tomography ; Dental Implants ; Humans ; Maxillary Sinus ; Prevalence ; Retention (Psychology)