1.Therapeutic Efectivity of Intralesional Injection of 5 - Fluorouracil to Basal Cell Carcinomas.
Korean Journal of Dermatology 1994;32(2):337-341
Basal cell carcinomas(BCCs) are usually treated with ablative proccdures, but a nonsurgical treatment would conserve tissue and obtain a better cosmetic out come as well as treat patients who refuse surgery or those who are not good surgical candidates. Because of inadequate drug penetration, low cure rates, high recurence rates, and adverse reactions, such as contact dermatitis, topical 5-fluorouracil(5-FU) is unsaitble to treat nodular BCCs. But, int,ralesional 5-FU has been reported to be effective for nodular BCCs. The efficacy and safety of intralesional injection of 5-FU have been evaluated for treatment of BCCs. The results revealed that intralesional injection of 5-FU seems to be effective in the treatment of various premalignant and malignant skin lesions as well as BCCs without side effects.
Carcinoma, Basal Cell*
;
Dermatitis, Contact
;
Fluorouracil*
;
Humans
;
Injections, Intralesional*
;
Skin
2.Acute myelogenous leukemia presenting with pericardial tamponade.
Jee Yun LEE ; Dong Won BYUN ; Jong Ho WON ; Dae Sik HONG ; Hee Sook PARK
Korean Journal of Hematology 1992;27(2):339-343
No abstract available.
Cardiac Tamponade*
;
Leukemia, Myeloid, Acute*
3.Two Cases of Allergic Contact Dermatitis to Rosehip Oil.
Hun Young JANG ; Yun Jeong LEE ; Dae Won KOO ; Chun Wook PARK ; Cheol Heon LEE
Annals of Dermatology 1996;8(2):114-116
No abstract available.
Dermatitis, Allergic Contact*
;
Rosa*
4.A Case of Infantile Acute hemorrhagic Edema.
Yun Jeong LEE ; Dae Won KOO ; Chun Wook PARK ; Cheol Heon LEE
Korean Journal of Dermatology 1994;32(2):332-336
Infantile acute hemorrhagic edema is a benign disease followed by a spontaneous eomplete recovery without sequelae, characterized by cockade purpura and inflamrntory edema on the face and extremities without any internal origin involvement in 4-month to 2-year-old infants. We report a case of infaniile acute hemorrhagic edema which occared in a 2-year-old female after an upper respiratory illness and compare the clinical and histologic features of this disorder with Henoch-Schonlein purpura.
Child, Preschool
;
Edema*
;
Extremities
;
Female
;
Humans
;
Infant
;
Purpura
;
Purpura, Schoenlein-Henoch
5.A Case of Endovascular Stent-Graft Implantation in Aortic Dissection mimicking Intramural Hematoma in Descending Thoracic Aorta.
Dae Keun SHIM ; Byoung Kwon LEE ; Jong Won HA ; Do Yun LEE ; Byung Chul CHANG ; Won Heum SHIM
Korean Circulation Journal 2001;31(3):347-352
Intramural hematoma(IMH) and penetrating aortic ulcer have been increasingly recognized as causes of acute aortic pathology in addition to aortic dissection. The presence of the intimal tear and a flap traversing the aortic lumen is considered to be a most reliable differential point of aortic dissection and IMH. Transesophageal echocardiography(TEE) has become a valuable modality for the diagnosis, prognosis and management of acute aortic syndrome with the unique advantages of portability and the ability to obtain high-resolution real time images. Endovascular Stent-graft placement over the primary entry tear may be an alternative to open surgery because it can close the intimal tear, which leads to thrombosis of the false lumen, excluding flow through the intimal tear and redirecting aortic flow exclusively into the true lumen. We report 88 year-old male with aortic dissection in descending thoracic aorta, successfully treated with endovascular Stent-graft implantation, which was mimicking intramural hematoma by its appearance and subclinical intimal tear diagnosed exclusively by TEE against other imaging studies.
Aged, 80 and over
;
Aorta, Thoracic*
;
Diagnosis
;
Hematoma*
;
Humans
;
Male
;
Pathology
;
Prognosis
;
Thrombosis
;
Ulcer
6.Abnormal Left Ventricular Blood Flow Pattern with Apical Involvement in Experimental Myocardial Infarction.
Dae Won SOHN ; Ki Hoon HAN ; Dae Gyun PARK ; Young Seok CHO ; Tae Jin YEUN ; Kyung Kuk HWANG ; Yun Shik CHOI ; Jung Don SEO ; Young Woo LEE
Korean Circulation Journal 1997;27(1):86-93
No abstract available.
Echocardiography
;
Myocardial Infarction*
7.Clinical Observation on Antihypertensive Effect of Indapamide(Fludex(R)).
Dae Won SOHN ; Byung Hee OH ; Young Bae PARK ; Yun Shik CHOI ; Jung Don SEO ; Young Woo LEE
Korean Circulation Journal 1988;18(3):447-453
The antihypertensive effect of Indapamide(Fludex(R)) was studied in 31 patients of essential hypertension and following results were obtained. 1) Daily dosage was 1mg b.i.d. and total duration of medication was weeks. 2) Mean systolic and diastolic blood pressure declined by 23mmHg(14%) and 18mmHg(17%) respectively. 3) Good or fair controls were achieved in 78% of patients. 4) There was no significant change in heart rate during and after treatment. 5) There were no significant changes in fasting blood sugar, serum creatinine, K+, uric acid, ca++, transaminase and cholesterol levels before and after treatment. 6) In 5 patients transient side effects were observed which resolved spontaneously. In view of these results Indapamide appears to be effective agent for the treatment of mild to moderate hypertension and dose not cause significant change in blood chemistry.
Blood Glucose
;
Blood Pressure
;
Chemistry
;
Cholesterol
;
Creatinine
;
Fasting
;
Heart Rate
;
Humans
;
Hypertension
;
Indapamide
;
Uric Acid
8.On the Plasma Triglyceride Determination in Normal Koreans.
Gie Seen KIM ; Yong In KIM ; Sang Ryong YOON ; Dae Yun CHANG ; Man Soo SONG ; Won Sang YOO
Korean Circulation Journal 1978;8(1):17-20
Since the first report on the blood triglyceride level of normal korean in 1962, more than 12 authors published their normal value ranging from 78.0~151.0mg% as mean value. In an attempt to establish normal triglyceride level in Korean, the timing of sampling and method of sample preservation were reevaluated in terms of quality control. Although the number of samples and tests were too small to make an unequivocal conclusion, the following results were observed. 1. Plasma triglyceride levels were stable on continuing fasting 12~16 hours, slightly decreased thereafter. 2. Samples kept in room temperature were stable up to 3 days and the triglyceride level dropped moderately on the 5th day. 3. No significant change in plasma triglyceride level was found with freezing up to one month. 4. Significant change in plasma triglyceride level was noted with repeated melting and refreezing of specimen. 5. The probable reasons for marked differences in normal value of plasma triglyceride level were discussed.
Fasting
;
Freezing
;
Plasma*
;
Quality Control
;
Reference Values
;
Triglycerides*
9.A Case of Complete Resolution of Aortic Dissection in the Descending Thoracic Aorta Treated with Endovascular Stent-Graft Implantation.
Dae Keun SHIM ; Hee Doo KYUNG ; Young Sup YOON ; Byung Chul CHANG ; Do Yun LEE ; Won Heum SHIM
Korean Circulation Journal 2000;30(12):1583-1588
The aortic dissection is an acute aortic syndrome, caused by an intimal tear and subsequent splitting of the media by the pulsatile blood flow. Though there would be differences in the origin of aortic dissection and therapeutic modalities, the intermediate and long-term prognoses are poor. Endovascular Stent-graft implantation is a revolutionary technique in the treatment of aortic dissection. The endovascular stent grafting in aortic dissection is less invasive and feasible method and is an effective tool for closing the entry site and promoting clot formation, reducing the size of the false lumen. Therefore, endovascular Stent-graft implantation makes possible the desirable remodelling of aorta. We report 33 year-old male with aortic dissection in the thoracic aorta, which was treated with endovascular Stent-graft implantation. Over the favorable remodelling, his dissection was healed completely by the endovascular treatment using Stent-graft.
Adult
;
Aorta
;
Aorta, Thoracic*
;
Blood Vessel Prosthesis
;
Humans
;
Male
;
Prognosis
10.Chondrosarcoma Arising from Benign Bone Tumor due to Malignant Transformation.
Wan hyeong CHO ; Won Seok SONG ; Chang Bae KONG ; Yun Suk HONG ; Jung Dong LEE ; Dae Geun JEON
The Journal of the Korean Bone and Joint Tumor Society 2011;17(1):17-22
PURPOSE: We analyzed the oncological outcome and prognostic factor of the chondrosarcoma arising from benign bone tumor due to malignant transformation. MATERIALS AND METHODS: From April 1986 to April 2009, 18 cases were considered eligible. We analyzed retrospectively the patient's characteristics and prognostic factors that affect to the local recurrence and distant metastasis. RESULTS: As classified by primary benign bone tumor, 4 cases were solitary osteochondroma, 11 cases were multiple osteochondromatosis and 3 cases were multiple enchondromatosis. The mean follow-up period was 85 months. The 5-year disease free survival rate of 18 patients was 85.9%. Their overall MSTS score was 25.2 (84%). There were local recurrence in 3 cases and no distant metastasis. We found that tumor location and surgical margin affected to the prognosis significantly. CONCLUSION: In secondary chondrosarcoma patients, the prognosis was good relatively and tumor location and surgical margin are important prognosis factor.
Chondrosarcoma
;
Disease-Free Survival
;
Enchondromatosis
;
Follow-Up Studies
;
Humans
;
Neoplasm Metastasis
;
Osteochondroma
;
Osteochondromatosis
;
Prognosis
;
Recurrence
;
Retrospective Studies