1.A Case of Rapidly Progressive Glomerulonephritis in Henoch-Schonlein Purpura.
Soo Hee CHANG ; Dae Sun JO ; Dae Yeol LEE
Journal of the Korean Society of Pediatric Nephrology 1997;1(1):82-85
A case of primary non-clear-cell adenocarcinoma of the vagina is reported occurring in a 65-year-old woman without exposure to diethylstilbestrol (DES) in utero. The adenocarcinoma did not appear to be associated with vaginal adenosis. It lacked clear cell component and interestingly composed of columnar epithelial cells of endocervical-type. Cytologically round to oval nuclei revealed one or more small nucleoli and fine granular chromatin pattern. Cytoplasm was plump, faintly basophilic and homogeneously stained. Histologically well differentiated columnar epithelial cells were arranged in trabecular pattern mainly, and also occasional glandular lumina and small solid sheets were found. Mitoses were hardly found.
Adenocarcinoma
;
Aged
;
Basophils
;
Cellular Structures
;
Chromatin
;
Cytoplasm
;
Diethylstilbestrol
;
Epithelial Cells
;
Female
;
Glomerulonephritis*
;
Humans
;
Mitosis
;
Purpura, Schoenlein-Henoch*
;
Vagina
2.Clinical Observation of Congenital Urinary Tract Anomalies.
Sun Jun KIM ; Dae Yeol LEE ; Soo Hee CHANG
Journal of the Korean Society of Pediatric Nephrology 1997;1(1):67-72
We present the cytologic features of a case of solid and papillary neoplasm of the pancreas. Cytologically, the tumor was composed of a monotonous population of polygonal cells containing eccentrically located round nuclei with one or two distinct small nucleoli and a finely stippled chromatin pattern. The tumor cells were similar to those of the islet cell tumor and showed isolated loosely aggregated and solid sheets or large cell clumps. The large cell clumps revealed a branching papillary structure containing fibrovascular central core, which is characteristic histologic feature of solid and papillary neoplasm of the pancreas. This case was confirmed by tissue examination including histochemical, immunohistochemical and electron microscopical studies. Ultrastructurally, the tumor cells contained a few membrane-bound electron dense granules.
Adenoma, Islet Cell
;
Chromatin
;
Pancreas
;
Urinary Tract*
3.Recent trend of multimodality treatment of the malignant anal tumor.
Dae Jig LEE ; Chang Soo KIM ; Eul Sam CHUNG
Journal of the Korean Surgical Society 1992;42(6):839-846
No abstract available.
4.Ca Effects on Synthesis and Secretion of Insulin-like Growth Factor(IGF-I) and IGF-Binding Proteins by the Perfased Rat Liver
Dae Yeol LEE ; Chang Won KANG ; Jung Soo KIM
Journal of Korean Society of Endocrinology 1996;11(2):189-198
Background: The insulin-like growth factors, IGF-I and
Animals
;
Calcimycin
;
Calcium
;
Egtazic Acid
;
Extracellular Fluid
;
Glucose
;
Hepatocytes
;
Insulin
;
Insulin-Like Growth Factor Binding Protein 3
;
Insulin-Like Growth Factor Binding Proteins
;
Insulin-Like Growth Factor I
;
Liver
;
Metabolism
;
Parathyroid Hormone
;
Perfusion
;
Rats
;
Somatomedins
5.A Diagnostic Significance of Transurethral and Transrectal Ultrasonography.
Korean Journal of Urology 1987;28(3):375-380
An ultrasonic scanner in the field of urology is described that can be used for transurethral as well as for transrectal scanning of the bladder and prostate. The bladder was visualized best by transurethral scanning, while the rectal approach was preferable for examination of the prostate. Transurethral ultrasonography was performed in 7 patients with bladder cancer. Transrectal ultrasonography was performed in 21 controls and 41 patients with prostatic disease. The following results were obtained: 1. Diagnostic accuracy of the staging of transurethral ultrasonography was 85.7% in bladder cancer. 2. The average values of maximum anterioposterior, superio-inferior and transverse diameter. obtained from ultrasonogram were 2.43+/-0.29cm, 3.27+/-0.41cm, 4.07+/-0.91cm in control group ;3.11+/-0.6lcm, 4.16+/-0.66 cm, 4.71+/-0.76cm in B.P.H.; 3.65+/-0.46cm, 4.88+/-0.23cm, 5.98+/-0.18cm in prostatic cancer. 3. Diagnostic accuracy of transrectal ultrasonography was 93% in B.P.H. and 80% in prostatic cancer. 4. Transurethral ultrasonography enabled us to determine the degree of tumor invasion of the bladder wall and was useful to help select appropriate therapy. Transrectal ultrasonography has proved especially in estimating prostatic size and in detecting pathology.
Humans
;
Pathology
;
Prostate
;
Prostatic Diseases
;
Prostatic Neoplasms
;
Ultrasonics
;
Ultrasonography*
;
Urinary Bladder
;
Urinary Bladder Neoplasms
;
Urology
6.Popliteal artery injury associated with severe trauma around the knee.
Sang Soo KIM ; Dae Moo SIM ; Hak Sun KIM ; Byoung Chang CHANG ; In Young CHOI
The Journal of the Korean Orthopaedic Association 1993;28(7):2380-2388
No abstract available.
Knee*
;
Popliteal Artery*
7.Alveolar Soft-Part Sarcoma of the Female Genital Tract.
Ji Young KIM ; Jong Dae WHANG ; Chang Soo PARK ; Duk Soo BAE ; Je Ho LEE
Korean Journal of Obstetrics and Gynecology 1998;41(11):2875-2878
Alveolar soft-part sarcoma of the female genital tract are extremely rare. Fewer than 30 cases have been described in the literature. We experienced a case of alveolar soft-part sarcoma of the female genital tract which was diagnosed by routine light microscopic study using ultrastructural and immunohistochemical stain. We report this case with a brief review of the literature.
Female*
;
Humans
;
Sarcoma, Alveolar Soft Part*
8.Survival, Differentiation and ATM Phenotype of PC-12 Cells by Down - regulation of AT Gene.
Ho Keun YI ; Soo Hee CHANG ; Dae Yeol LEE ; Jung Soo KIM ; Pyoung Han HWANG
Journal of the Korean Cancer Association 1999;31(5):1065-1073
PURPOSE: Ataxia Telangiectasia (AT) is a hereditary multi-systemic disease resulting from mutations of AT gene and is characterized by progressive neurodegeneration, cancer, immune system defects, and hypersensitivity to ionizing radiation. AT gene has a homologue sequence of PI3-kinase. The activity and cellular function of PI3-kinase in AT gene remains unclear. This study was undertaken to evaluate the function of AT gene through the effect on cell survival and differentiation by the inhibition of AT gene expression. MATERIALS AND METHODS: NH2-terminal portion of AT gene was isolated from MCF-7 cells by RT-PCR. The isolated DNA fragment was ligated in reverse orientation in pcDNA3. This antisense ATM expression vector was transfected to PC-12 cells by calcium phosphate method, and the transformed cells were selected using G418 and immunohisto- chemistry. To analyze the cell survival and differentiation, cells were cultured in serum free medium supplemented with/without NGF. We performed the immunoprecipitation for the p53 induction of cells after ionizing radiation, and the FACS for the apoptosis of cells after the exposure of wortmanin. RESULTS: PC-12 cells which down-regulated AT gene (like ATM, AT mutated) showed decreased survival and ceased differentiation with NGF. Also, PC-12 (ATM) cells showed increased apoptosis with wortmanin and reduced or delayed p53 induction after ionizingradiation. CONCLUSION: Results obtained from these studies suggest that AT gene regulates survival and differentiation of PC-12 cells through PI3-kinase activity. It seems that apoptosis is induced by the inhibition of AT gene expression.
Apoptosis
;
Ataxia Telangiectasia
;
Calcium
;
Cell Survival
;
Chemistry
;
DNA
;
Gene Expression
;
Hypersensitivity
;
Immune System
;
Immunoprecipitation
;
MCF-7 Cells
;
Nerve Growth Factor
;
Phenotype*
;
Phosphatidylinositol 3-Kinases
;
Radiation, Ionizing
9.A Case of the Renal Artery Aneurysm Associated with the Dysplastic Kidney.
Tae Hee PARK ; Soo Hee CHANG ; Young Min HAN ; Soo Chul CHO ; Dae Yeol LEE
Journal of the Korean Pediatric Society 1995;38(11):1571-1576
No abstract available.
Aneurysm*
;
Kidney*
;
Renal Artery*
10.A Case Report of Acrorenal Syndrome.
Soo Hee CHANG ; Jo Seph CHOI ; Soo Chul CHO ; Dae Yeol LEE
Journal of the Korean Pediatric Society 1995;38(8):1151-1154
No abstract available.