No abstract available.
Abruptio Placentae* ; Female ; Pregnancy

No abstract available.
Abruptio Placentae* ; Female ; Pregnancy

Nevoid basal cell carcinoma syndrome (NBCCS) is a rare autosomal genetic disease caused by a PTCH mutation. The disease is characterized by multiple basal cell carcinomas of the skin, multiple keratocystic odontogenic tumors (KCOTs) in the jaw, palmar and/or plantar pits, bifid ribs, ectopic calcification of the falx cerebri, and skeletal abnormalities. Early diagnosis is difficult in many cases because there may be a number of systemic symptoms. The purpose of this study is to report the case of a 12-year-old girl who was hospitalized with multiple KCOTs that occurred in the upper and lower jaws. Through characteristic clinical symptoms and radiologic findings, she was finally diagnosed as having NBCCS. This study also aims to organize the symptoms often observed in Korea using previously published case reports to provide useful information for the early diagnosis of NBCCS.
Basal Cell Nevus Syndrome* ; Carcinoma, Basal Cell ; Child ; Early Diagnosis ; Female ; Humans ; Jaw ; Korea ; Odontogenic Cysts ; Odontogenic Tumors ; Ribs ; Skin

Kabuki (Niikawa-Kuroki) syndrome was first reported by Niikawa et al(1981). The faces of the patients are similar to the make-up of traditional Japanese Kabuki actors: long palpebral fissures, an ectropium of the lateral third of the eyelids,and arching eyebrows with sparse lateral halves. Craniofacial findings include a depressed nasal tip, short nasal septum, large and prominent ears, and micrognathia. Other main features area mild to moderate mental deficiency, short stature, skeletal and dermatoglyphic abnormalities, including prominent finger tip pads. Oral anomalies are common in KS(over 60percent) and include abnormal dentition, widely spaced teeth, cleft palate or lip, high vault of palate, hypodontia, conical incisors, screw driver-shaped incisors and ectopic upper 6-year molars. The increased occurrence of cleft lip and palate or the development of a high vault of palate has been described by a number of authors. This condition is believed to be common in Japan, but has been reported from other parts of the world. The objective of this presentation is to report a case of this syndrome in six-year-old girl, with characteristic findings.
Anodontia ; Asian Continental Ancestry Group ; Cleft Lip ; Cleft Palate ; Dentition ; Dermatoglyphics ; Ear ; Eyebrows ; Female ; Fingers ; Humans ; Incisor ; Intellectual Disability ; Japan ; Lip ; Molar ; Nasal Septum ; Palate ; Tooth

Cleft Lip ; Congenital Abnormalities ; Humans ; Jaw Abnormalities ; Malocclusion ; Nose ; Palate ; Rhinoplasty ; Succinates

Adult ; Female ; Hemangioma ; Humans ; Mouth ; Mouth Floor ; Neurilemmoma ; Peripheral Nerves ; Schwann Cells ; Tongue

Methyl bromide is a commonly used fumigant to disinfect soil, grains, and warehouses. The accumulation of danger-ous concentrations can produce various neurotoxic effects in humans. A 45-year-old man, who had worked in the fumi-gation business, presented with polyneuropathy, optic neuropathy, and cerebellar sign, and serially sampled blood, urine and cerebrospinal fluid showed significant elevation of methyl bromide concentration. Regular education to workers and strict adherence to the safety precautions are needed to avoid the risk of toxicity associated with methyl bromide fumigation.
Edible Grain ; Cerebellar Ataxia* ; Cerebrospinal Fluid ; Commerce ; Education ; Fumigation ; Humans ; Middle Aged ; Optic Nerve Diseases* ; Poisoning* ; Polyneuropathies* ; Soil

Likely to be the most common oral cancer, squamous cell carcinoma(SCC) of the tongue accounts for about 20% of all oral and pharyngeal cancers. SCC of the tongue frequently arises in the lateral border, and if it metastasize, it occurs on submandibular gland and neck lymph nodes. Location of the primary lesions and neck lymph node metastasis affect the prognosis and decrease survival rate of patients with carcinoma of the tongue. The authors experienced the patient with contralateral neck lymph node metastasis of SCC of the tongue. The patient came to our department with chief complaint of elevated lesion on left lateral border of the tongue. The mass was diagnosed as T2N0M0, Stage II invasive SCC of oral tongue. Computed tomography(CT) & magnetic resonance imaging(MRI) which were taken before the operation showed no significant finding of metastasis. Surgical mass removal and preventive neck dissection on the left side were done. While follow up PET/CT, contralateral neck lymph node metastasis(right side, level II) was detected, and re-operation(Rt. side RND) was done. There are few studies concerning the contralateral neck lymph node metastasis related with SCC of the tongue. The purpose of this report is to introduce the uncommon case of contralateral neck lymph node metastasis occurred in the T2-stage of SCC of the tongue treated by surgical resection.
Carcinoma, Squamous Cell ; Follow-Up Studies ; Humans ; Lymph Nodes ; Magnetic Resonance Spectroscopy ; Mouth Neoplasms ; Neck ; Neck Dissection ; Neoplasm Metastasis ; Pharyngeal Neoplasms ; Porphyrins ; Prognosis ; Submandibular Gland ; Survival Rate ; Tongue ; Tongue Neoplasms

INTRODUCTION: Heat shock protein70 (HSP70) is a highly conserved family of proteins produced after a variety of stresses. Many studies reported that the overexpression of HSP70 can improve the prognosis of the patients with sepsis through a reduction of the nitric oxide concentration. However, these results only revealed the effect of HSP70 and nitric oxide. No studies have examined the relationship between HSP70 and nitric oxide. The aim of this study was to evaluate the effect of the overexpression of HSP70 on the expression of inducible nitric oxide synthase and the nitric oxide concentration. In addition, the mechanism of the relationship of HSP70 and inducible nitric oxide synthase (iNOS) in sepsis was examined. MATERIALS AND METHODS: The experiments were performed on male sprague-dawley rats. Sepsis was induced by a cecal ligation and puncture (CLP). Glutamine (GLN) or saline was administered 1 hour after the initiation of sepsis. Serum and lung tissues were acquired from the rats 12 hours or 24 hours after the initiation of sepsis. The nitric oxide concentration, the expression of HSP70 in lung, and the gene expression of iNOS in lung were analyzed. The three groups, sham operation, CLP and CLP+GLN, were compared. RESULTS: Compared to the other groups, in CLP+GLN, GLN administered after the initiation of sepsis enhanced the expression of HSP70 in the lung at 12 hours (47.19+/-10.04 vs. 33.22+/-8.28, P=0.025) and 24 hours (47.06+/-10.60 vs. 31.90+/-4.83, P=0.004). In CLP+GLN, GLN attenuated the expression of iNOS messenger RNA (mRNA) in the lung at 12 hours (5,513.73+/-1,051.60 vs. 4,167.17+/-951.59, P=0.025) and 24 hours (18,740.27 +/-8,241.20 vs. 9,437.65+/-2,521.07, P=0.016), and reduced the concentration of nitric oxide in the serum at 12 hours (0.86+/-0.48 vs. 3.82+/-2.53, P=0.016) and 24 hours (0.39+/-0.25 vs. 1.85+/-1.70, P=0.025). CONCLUSION: The overexpression of HSP70 induced by the administration of GLN in sepsis attenuates the expression of the iNOS gene but reduces the nitric oxide concentration.
Animals ; Gene Expression ; Glutamine ; Heat-Shock Proteins ; Hot Temperature ; HSP70 Heat-Shock Proteins ; Humans ; Ligation ; Lung ; Male ; Nitric Oxide ; Nitric Oxide Synthase ; Nitric Oxide Synthase Type II ; Prognosis ; Proteins ; Punctures ; Rats ; Rats, Sprague-Dawley ; RNA, Messenger ; Salicylamides ; Sepsis ; Shock

INTRODUCTION: The enlargement and deformation of the orbit give rise to a visible enophthalmos. As a consequence, a disturbance of eye motility together with double images is likely to occur. This study examined the degree of enophthalmos according to the extent of orbital wall fracture and volume of herniated orbital tissue in blowout fractures of the medial and inferior orbital wall. MATERIALS AND METHODS: This study was performed on patients diagnosed with medial and inferior orbital wall fractures at the Department of Oral and maxillofacial surgery, Chonbuk National University Hospital from 2007 to 2009. The patients' age, gender, etiology of fracture and degree of enophthalmos were investigated. The changes in the degree of enophthalomos, diplopia and ocular motility restriction after operation were examined. RESULTS: The degree of enophthalomos increased with increasing extent of orbital wall fracture and volume of herniated orbital tissue. CONCLUSION: Whether to perform the operation is decided after measuring the extent of the orbital wall fracture and volume of herniated orbital tissue using computed tomography (CT), time for the decision of operation can be shortened. This can cause a decrease in the complications of orbital wall fractures.
Diplopia ; Enophthalmos ; Eye ; Humans ; Orbit ; Surgery, Oral