14 cases of femoral shaft fractures were treated with cast-brace for two years from June, 1974 to June, 1976 at the Department of Orthopedic Surgery, College of Medicine, Seoul National University Hospital. The results were as followings; 1. Of the 14 cases, eleven cases were male and three were female, and they were between 18 to 51 years of ages. 2. The fracture site was accounted that three of 14 cases were at the distal one third of the femur and the other eleven at the mid one third with four cases being comminuted. 3. 7 cases were treated with cast-brace initially, and the other 7 cases were secondarily treated, because of being complicated. 4. The average time of fracture healing was 14 weeks in the cases with cast-brace which is compared with 20 weeks of spica-cast control group in the same period. 5. One of 7 cases treated primarily developed shortening and angulation, which was corrected by open reduction and internal fixation.
Clinical Study ; Female ; Femoral Fractures ; Femur ; Fracture Healing ; Humans ; Male ; Orthopedics ; Seoul

No abstract available.
Follow-Up Studies* ; Occupational Diseases*

No abstract available.
Knee* ; Passive Cutaneous Anaphylaxis*

The suture materials influence the success of microvascular anastomosis importantly. The purpose of this experiment is to observe the effect of absorbable suture material and nonabsorbable suture material in microvascular anastomosis. The study was carried out on one side of carotid arteries of fourty rats which were anesthetized intraperitoneally with urethane. The experimental procedures differed in two groups, Group A in which the carotid artery was sutured with 10-0 monofilament polyglycolic acid, Group B in which the carotid artery was sutured with 10-0 monofilament nylon. Gross and histological examination were used to compare the results of end to end suture above two suture material. The results were as follows. 1. Nylon had greater tensile strength and ease of handling than polyglycolic acid, but held knots poorly. 2. Polyglycolic acid had difficult handling and lesser tenslie strength than nylon, but held knots hardly. 3. Polyglycolic acid had high patency rate, some lesser tissue response than nylon.
Animals ; Arteries ; Carotid Arteries ; Nylons ; Polyglycolic Acid ; Rats ; Sutures ; Tensile Strength ; Urethane

No abstract available.
Lithotripsy* ; Shock*

The authors reviewed 73 cases of ligament injuries in 70 patients from October, 1972 to June, 1978 who were admitted and treated in the Orthopedic Department at Kyung Hee University Hospital. Of 70 patients, the sex distribution was 59 patients (84%) in male and 11 patients (16%) in female. The high incidence was in age group from 21 to 40 years, that was 46 patients (55%). Traffic accident was most common cause of ligament injuries that was 61 patients (87%). Methods of treatment were direct repair, reconstruction and conservative treatment. Degree of angle and distance were measured with stress radiogram. Degree of angle and distance were also compared with normal and abnormal knee joints. Eleven cases were treated conservatively, and 62 cases, operatively, of whlch direct repair performed in 56 cases and reconstructive surgery, in 6 casea, The summary were as follows: 1. The result was better in the group with conservative treatment, as compared with operative treatment. And conservative treatment was applied only in single ligament injuries. 2. In normal knee joint, degree of angle was distributed evenly in the range of 0° to 10°, and distance was in the range of 0 to 10 mm. 3. In stress radiograrn, the significance of ligament injuries was present in more than 10° and 10 mm. 4. The measurement of distance seemed to be more meaningful than degree of angle. 5. It is helpful to measure the degree of angle and distance in diagnosis of ligament injuries, though not absolute.
Accidents, Traffic ; Clinical Study ; Diagnosis ; Female ; Humans ; Incidence ; Knee Joint ; Knee ; Ligaments ; Male ; Orthopedics ; Sex Distribution

No abstract available in English.
Enterocolitis, Pseudomembranous

Mitomycin-C(MMC) has been increasingly used as adjunct chemotherapy during glaucoma filtering surgery in order to increase the success rate, because of its ability to inhibit the proliferation of fibroblast. Although MMC demonstrates toxic effects in the anterior segment of the eye, few studies on its retinal toxicity have been reported. Therefore, this study was performed to investigate the retinal toxicity of MMC in the rabbit after intra cameral irrigation. After anesthesia, 1 ml of MMC(40 mg/ml) was intracamerally irrigated in right eye and 1ml of balanced salt solution(BSS) was used as control in the left eye. The electroretinogram was checked before, 2 and 7 days after intracameral MMC irrigation. The fundus examination and histopathology by light microscopy and transmission electron microscopy were performed at 7days after MMC irrigation. On electroretinogram, scotopic b-wave amplitude in MMC irrigated eye was significantly decreased 7 days after irrigation as compared with BSS irrigated eye. The retina in MMC irrigated eye was normal on the fundus findings and histopathology by light microscopy and transmission electron microscopy 7 days after irrigation. This findings suggest that intracameral irrigation of MMC may induce the functional disturbance rather than structural alteration of retina.
Anesthesia ; Drug Therapy ; Fibroblasts ; Filtering Surgery ; Glaucoma ; Microscopy ; Microscopy, Electron, Transmission ; Mitomycin* ; Retina ; Retinaldehyde

OBJECTIVES: This study was aimed at investigating the effect of haloperidol on alcohol craving in patients wih alcohol dependence. METHODS: Eighteen patients with alcohol dependence were divided randomly into two groups of nine patients each: one haloperidol group and the other, placebo group. The medication for each group was done for 14 days. Alcohol craving and difficulty in resisting drinking were measured on day 1 and day 14, each consisting of a series of four assessments. Assessment 0 was basal levels. Assessment 1 was made 3 hours after medication. Assessment 2 was made after alcohol intake in a dose of 0.4gm of 100% alcohol/kg body weight and assessment 3 was done after the second alcohol intake in the same amount. RESULTS: The results were as follows: 1) With acute treatment, placebo group showed a significant increase in alcohol craving whereas haloperidol group did not show any change after the first and second alcohol intake. 2) With chronic treatment, both groups showed significant increase in the alcohol craving after alcohol intake. 3) Haloperidol did not increase difficulty in resisting drinking after acute treatment, however, with chronic treatment, it resulted in a significant increase of the difficulty in resisting drinking. CONCLUSIONS: From these results, the authors suggest that an acute treatment of haloperidol lowers alcohol craving in patients with alcohol dependence, but the effect does not maintain itself with chronic treatment.
Alcoholism* ; Body Weight ; Drinking ; Haloperidol* ; Humans

Chymopapain was discovered by Jensen in 1941, and in 1963 Smith demonstrated the chondrolytic properties of chymopapain. Since then, many patients have been injected with this agent. Although there are evidences of neurotoxicity to chymopapain in animals, adverse effects in humans have rarely been reported. We present a case delayed onset of paraplegia after chymopapain chemonucleolysis and review the neurotoxicities to chymopapain.
Animals ; Chymopapain ; Humans ; Intervertebral Disc Chemolysis* ; Paraplegia*