1.Mediastinal Hemangioma: Report of a case.
Jong Ok KIM ; Bum Kyeong KIM ; Kyoung Hee KIM ; Dae Young KANG ; Kwang Sun SUH
Korean Journal of Pathology 1997;31(9):891-894
Benign hemangioma of the mediastinum is rare. This slowly growing tumor is described as well circumscribed, cystic, hemorrhagic tumor. Histologically it can be differentiated into capillary or cavernous form. We present a case of mediastinal hemangioma. A 20-year-old-man was presented with a slowly growing posterior mediastinal mass of 6 years duration, 8x6 cm in size. The mass was relatively well defined but focally invasive. Microscopically, it was differentiated into vessels of capillary, cavernous, and venous patterns. A solid cellular proliferation with inconspicuous capillary lumens was focally seen. The stroma between variable-sized vessels showed marked myxoid change associated with some smooth muscle bundles and adipose tissue. Ultrastructurally, areas of solid cellular proliferation showed formation of lumens. These lumens were lined by active endothelial cells showing plasmalemmal vesicles and Weibel-Palade bodies on the abluminal surface.
Adipose Tissue
;
Capillaries
;
Cell Proliferation
;
Endothelial Cells
;
Hemangioma*
;
Mediastinum
;
Muscle, Smooth
;
Weibel-Palade Bodies
2.Burkitt's Lymphoma Developed Acute Leukemia: A report of two cases.
Young Dae KIM ; Kyoung Ja HAN ; Byoung Kee KIM ; Sun Moo KIM
Korean Journal of Pathology 1985;19(2):207-213
Burkitt's lymphoma with a frankly leukemic picture is an extremely rare condition, and usually has a very acute course with a poor prognosis. The authors experienced two cases of Burkitt's lymphoma developed acute leukemia. The first case was 8 years-old boy who had rapidly growing large abdominal mass, which revealed typical Burkitt's lymphoma with characteristic "starrysky" pattern. The second case was 20 year old male who had not definite tumor mass. Their peripheral blood and bone marrow aspiration revealed acute leukemia with multiple vacuolated lymphoblast of Burkitt's type. We report these cases with brief review of literatures.
Male
;
Humans
3.Renal Streaky Artifact during Contrast-Enhanced Abdominal and Pelvic CT' Comparison of High versus Low Osmolality Contrast Media.
Jong Chul KIM ; Dae Hong KIM ; Chung Keun LEE ; Kyoung Suk SHIN
Journal of the Korean Radiological Society 1994;30(6):1129-1133
PURPOSE: Introduction of low osmolality contrast agent(LOCA) has allowed safer, more comfortable contrast-enhanced CT examination, but there has been significant increase in image degradation when evaluating the kidneys due to streaky artifact. The authors reviewed findings of contrast-enhanced abdominal and pelvic computed tomography(CT) to know the difference of renal streaky artifact between a high osmolality contrast agent (HOCA) and LOCA. MATERIALS AND METHODS: This study included two hundred contrast-enhanced CT in 200 patients, 100 performed with HOCA(meglumine ioglicate, 150ml) and 100 performed with LOCA (iopromide, 150ml). The severity of renal streaky artifact was compared between HOCA and LOCA groups. RESULTS: Of the scans performed with HOCA, 40 had no artifact, 52 had grade I artifact, 6 had grade II artifact, and 2 had grade III artifact Of the scans performed with LOCA, 23 had no artifact, 44 had grade I artifact, 29 had grade II artifact, and 4 had grade III artifact. There was significant difference in the degree of the streaky artifact depending upon the osmolality of the contrast media used(by {{{{x^2}}}}-test, P=.0001). CONCLUSION: The results of this study revealed a statistically significant increased incidence of artifacts and distortions of renal image with LOCA when compared with HOCA.
Artifacts*
;
Contrast Media*
;
Humans
;
Incidence
;
Kidney
;
Osmolar Concentration*
;
Tomography, X-Ray Computed
4.A Case of Hyperimmunoglobulinemia E Syndrome.
Seung Hyun MOON ; Dae Hun SUH ; Kyu Han KIM ; Kyoung Chan PARK ; Jai Il YOUN
Korean Journal of Dermatology 1998;36(3):482-486
The hyperimmunoglobulinemia E (Jobs) syndrome (HIES) is characterized by marked elevated levels of IgE, recurrent cutaneous and systemic staphylococcal infections, atopic-like dermatitis, and defective neutrophil chemotaxis. Three cases of HIES have been reported in Korea, but not in the dermatology literature. We report a case of HIES with cutaneous infections and MRSA (methicillin-resistant Staphylococcus aureus). A 15-month-old girl presented with intractable pruritic excoriated papular pustular skin lesions and multiple subcutaneous abscesses. Surgical drainage of the abscesses and a course of antibiotic treatment in addition to topical steroids for about 7 weeks resulted in a remarkable improvement.
Abscess
;
Chemotaxis
;
Dermatitis
;
Dermatology
;
Drainage
;
Female
;
Humans
;
Hypergammaglobulinemia*
;
Immunoglobulin E
;
Infant
;
Job Syndrome*
;
Korea
;
Methicillin-Resistant Staphylococcus aureus
;
Neutrophils
;
Skin
;
Staphylococcal Infections
;
Staphylococcus
;
Steroids
5.Corrigendum: Correction of Acknowledgments: Epidemiology of Childhood Obesity in Korea.
Endocrinology and Metabolism 2017;32(1):144-144
In our recently published article, there were some missing contents in the Acknowledgments section, which should be properly added as follows.
6.Relationship between Expressions of Tumor - Associated Antigen MAGE-3 and p53 Proteins during Cell Cycle by Bivariate Analysis of Flow Cytometry.
Hee Kyoung CHANG ; Deok Jun KIM ; Kang Dae LEE ; Hwan Jung ROH ; G SPAGNOLI
Journal of the Korean Cancer Association 1999;31(4):784-792
PURPOSE: MAGE (melanoma antigen gene) is a tumor associated antigen, presented by HLA class I molecules, which is recognized by cytotoxic T lymphocytes. The expression of MAGE proteins are confined to malignant tumor tissues, except for the normal testis and placental tissues. Therefore, MAGE may be a potential target for immunotherapy of malignant tumors. However, biological aspects associated with the cell cycle are not yet described. MATERIALS AND METHODS: The material used for this study was a novel human squamous cell carcinoma cell line (PNUH-12) from the hypopharynx, which had one point mutation of 78th base, C to G, in exon 7 of p53 gene. To understand the role of MAGE in relation to cell cycle and its relationship with p53 as the Gl checkpoint regulator, the expressions of MAGE-3 protein and mvtant p53 (Mtp53) were accessed by flow cytometry and immunohistochemistry. Double stains for MAGE-3/Mtp53 was analyzed with bivariate flow cytometry. DNA histograms using MAGE-3/PI (DNA) and Mtp53/PI (DNA) were also analyzed. RESULTS: The expression rate of MAGE-3 and Mtp53 were 83% and 85%, respectively. MAGE-3 was expressed in cytoplasm, while M:p53 were expressed in the nuclei of the tumor cells on the immunohistochemical sections. With bivariate analyses, coexpression rate of MAGE-3/Mtp53 was 0.96, and MAGE-3 and Mtp53 constantly showed high levels throughout the cell cycle except Go. CONCLUSIONS: These results mean that (I) MAGE-3 might have yet unknown relationship with mutant p53, (2) expressions of MAGE-3 and Mtp53 are not dependent on the cell cycle in PNUH-12 hypopharyngeal squamous carcinoma cell line, and suggest that MAGE-3 might have a role as important as p53 during the development of malignant tumors.
Carcinoma, Squamous Cell
;
Cell Cycle*
;
Cell Line
;
Coloring Agents
;
Cytoplasm
;
DNA
;
Exons
;
Flow Cytometry*
;
Genes, p53
;
Humans
;
Hypopharynx
;
Immunohistochemistry
;
Immunotherapy
;
Point Mutation
;
T-Lymphocytes, Cytotoxic
;
Testis
7.A Case of Lichen Spinulosus with an Histologic Finding of Follicular Mucinosis.
Dae Heon OH ; Kyoung Tae PARK ; Jeong Soo KIM ; Hee Joon YU
Annals of Dermatology 2005;17(2):79-82
No abstract available.
Lichens*
;
Mucinosis, Follicular*
8.Visceral Fat Mass Has Stronger Associations with Diabetes and Prediabetes than Other Anthropometric Obesity Indicators among Korean Adults.
Suk Hwa JUNG ; Kyoung Hwa HA ; Dae Jung KIM
Yonsei Medical Journal 2016;57(3):674-680
PURPOSE: This study determined which obesity measurement correlates the best with diabetes and prediabetes. MATERIALS AND METHODS: This cross-sectional study enrolled 1603 subjects (611 men, 992 women; age 30-64 years) at the Cardiovascular and Metabolic Diseases Etiology Research Center. Body mass index, waist circumference, waist-height ratio, waist-hip ratio, waist-thigh ratio, and visceral fat were used as measures of obesity. Visceral fat was acquired using dual-energy X-ray absorptiometry (DXA). The prevalences of diabetes and prediabetes were defined using the criteria in the American Diabetes Association 2015 guidelines. RESULTS: After adjusting for age and other potential confounding factors, participants with a visceral fat mass in the upper 10th percentile had a higher odds ratio (OR) for diabetes and prediabetes than the upper 10th percentile of other adiposity indices [men, OR=15.9, 95% confidence interval (CI)=6.4-39.2; women, OR=6.9, 95% CI=3.5-13.7]. Visceral fat mass also had the highest area under the curve with diabetes and prediabetes in both men (0.69, 95% CI=0.64-0.73) and women (0.70, 95% CI=0.67-0.74) compared to other anthropometric measurements of obesity. CONCLUSION: Visceral fat mass measured using DXA is an indicator of diabetes or prediabetes, due to its ability to differentiate between abdominal visceral and subcutaneous fat.
Absorptiometry, Photon
;
*Adiposity
;
Adult
;
Anthropometry
;
Asian Continental Ancestry Group/*statistics & numerical data
;
Biomarkers/blood
;
Body Mass Index
;
Cross-Sectional Studies
;
Diabetes Mellitus/*ethnology
;
Female
;
Humans
;
*Intra-Abdominal Fat
;
Male
;
Middle Aged
;
Obesity/complications/*ethnology
;
Odds Ratio
;
Prediabetic State/*ethnology
;
Prevalence
;
Prospective Studies
;
Republic of Korea/epidemiology
;
Waist Circumference
9.Fournier's Gangrene: A report of one case.
Kyoung Hwan KIM ; Yoe Dae YOON
Journal of the Korean Society of Coloproctology 1997;13(4):643-647
Fournier's gangrene is a rare infection with high mortality rate. it consists of a mixed bacterial infectin of the skin, subcutaneous tissues and superficial fascia of the perinium and genitalia. Old patients especially with diabetes mellitus, alcoholism and maligancy are more affected. This disease requires prompt treatment: early diagnosis, broad spectrum antibiotic therapy, nutritional support and immediate extensive surgial debridement are necessary We report one case of Fournier's gangrene associated with diabetes mellitus.
Alcoholism
;
Debridement
;
Diabetes Mellitus
;
Early Diagnosis
;
Fournier Gangrene*
;
Genitalia
;
Humans
;
Mortality
;
Nutritional Support
;
Skin
;
Subcutaneous Tissue
10.The Effects of Tracheal Intubation with McCoy or Macintosh Laryngoscope on Blood Pressure, Heart Rate.
Jin Soo JOO ; Youn Suk LEE ; Dae Hyun JO ; Hae Kyoung KIM ; Choon Kun CHUNG
Korean Journal of Anesthesiology 1997;33(4):648-652
BACKGROUND: The aim of this study was to compare the cardiovascular changes followed by laryngoscopy with the McCoy laryngoscope blade with those followed by laryngoscopy with the Macintosh laryngoscope blade. METHODS: Forty eight patients were randomly divided into two groups. Following induction with fentanyl 2 mcg/kg and thiopental 5 mg/kg, and muscle relaxation with vecuronium 0.1 mg/kg, the vocal cords were visualized with either the McCoy or the Macintosh laryngoscope blade, then tracheal intubation was performed. Heart rate and arterial blood pressure were measured just before and after laryngoscopy, and 1, 3 and 5 min later. RESULTS: There was a significant increase in both heart rate and arterial blood pressure after tracheal intubation using the Macintosh laryngoscope. Also, use of the McCoy blade resulted in a significant increase in both heart rate and arterial blood pressure. CONCLUSIONS: There was no significant difference on arterial pressure and heart rate to laryngoscopy and tracheal intubation with either the McCoy blade or the Macintosh.
Arterial Pressure
;
Blood Pressure*
;
Fentanyl
;
Heart Rate*
;
Heart*
;
Humans
;
Intubation*
;
Laryngoscopes*
;
Laryngoscopy
;
Muscle Relaxation
;
Thiopental
;
Vecuronium Bromide
;
Vocal Cords