1.A Case of Calciphylaxsis.
Hyun Seung LEE ; Kwang Hyun CHO ; Dae Seog HEO ; Jai Kyoung KOH
Korean Journal of Dermatology 1999;37(1):87-90
Calciphylaxsis is a rare and life-threatening condition of progressive cutaneous necrosis secondary to calcification of small and medium-sized blood vessels. It is seen almost exclusively in patients with end-stage renal disease, in a setting of secondary hyperparathyroidism and hypercalcemia resulting in metastatic vascular calcification, We experienced a case of calciphylaxsis manifested with chara- cteristic cutaneous lesions that began as tender violaceous livedoid discolorations and subsequent ulceration on the proximal aspect of the extremities and on the lower part of the abdomen. Histologically, calcification is found in small and medium-sized blood vessels in the deep dermis and subcutaneous tissue. The patient had been treated for hypercalcemia, not complicating renal failure, but the cause of hypercalcemia was not found. However, the hypercalcemia was contolled and the skin lesions also improved after oral prednisolone therapy. Our case is a rare presentation of calciphylaxsis in the absence of renal failure, reversibly improved.
Abdomen
;
Blood Vessels
;
Dermis
;
Extremities
;
Humans
;
Hypercalcemia
;
Hyperparathyroidism, Secondary
;
Kidney Failure, Chronic
;
Necrosis
;
Prednisolone
;
Renal Insufficiency
;
Skin
;
Subcutaneous Tissue
;
Ulcer
;
Vascular Calcification
2.Spontaneous Cervical Spondylodiscitis and Epidural Abscess Caused by Klebsiella Pneumonia-single Stage Operation with Decompressive Corpectomy and Autologous Bone Fusion.
Min Seok KIM ; Dae Chul CHO ; Joo Kyoung SUNG
Korean Journal of Spine 2008;5(3):237-240
We present a very rare case of spontaneous cervical spondylodiscitis and epidural abscess caused by Klebsiella pneumonia. A 45-year-old man presented with severe posterior neck pain radiating down both arms with decreased range of motion of the neck. He also complained of paresthesia of the upper extremities and a subjective weakness of his right arm. Magnetic resonance imaging (MRI) revealed spondylodiscitis and epidural abscess on the C5 and C6. In order to obtain adequate drainage of the abscess and complete removal of granulation tissues we performed a total decompressive corpectomy of C5 and C6. After drainage of the abscess, single stage autologous iliac bone graft was performed. The patient was followed by three months with antibiotic treatment confirmed to be sensitive to the organism. Klebsiella pneumonia was cultured postoperatively from the surgical biopsy samples. The patient recovered with no complications and the postoperative MRI showed improvement of the lesions.
Abscess
;
Arm
;
Biopsy
;
Decompression
;
Discitis
;
Drainage
;
Epidural Abscess
;
Granulation Tissue
;
Humans
;
Klebsiella
;
Magnetic Resonance Imaging
;
Middle Aged
;
Neck
;
Neck Pain
;
Paresthesia
;
Pneumonia
;
Range of Motion, Articular
;
Transplants
;
Upper Extremity
3.Brucellar Spondylodiscitis in an Endemic Bovine Brucellosis Region of Korea: A Case Report.
Ki Su PARK ; Dae Chul CHO ; Joo Kyoung SUNG
Korean Journal of Spine 2008;5(4):267-270
Human brucellosis is an endemic zoonotic disease that is rare in Korea. However, there have been regional increases in its prevalence. Spondylodiscitis is a common osteoarticular complication of brucellar infection and is difficult to diag nose- because the clinical presentation is often variable and nonspecific. We report the case of a 56-year-old male with brucellar spondylodiscitis who was from Gyeongsangbuk-do, an endemic region of bovine brucellosis in Korea.
Animals
;
Brucellosis
;
Brucellosis, Bovine
;
Cattle
;
Discitis
;
Humans
;
Korea
;
Male
;
Middle Aged
;
Prevalence
4.Neoadjuvant chemotherapy with 5-fluorouracial infusion and cisplatin for locally advanced, untreated squamous cell carcinoma of the head and neck.
Myung Jin KIM ; Kyoung Won KIM ; Yong Seok CHO ; Ho Kyun CHUNG ; Yung Jue BANG ; Dae Seog HEO
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1993;19(4):573-582
No abstract available.
Carcinoma, Squamous Cell*
;
Cisplatin*
;
Drug Therapy*
;
Head*
;
Neck*
5.Epidural Hematoma Related with Low-Dose Aspirin : Complete Recovery without Surgical Treatment.
Kyoung Tae KIM ; Dae Chul CHO ; Suk Won AHN ; Suk Hyung KANG
Journal of Korean Neurosurgical Society 2012;51(5):308-311
Hemorrhagic complications associated with aspirin use occur primarily at skin or gastrointestinal sites but can occasionally occur in the central nervous system. In particular, spontaneous spinal epidural hemorrhage (SSEH) associated with aspirin is very rare. We report a case of low-dose (100 mg daily) aspirin-related SSEH that was successfully treated with medical management. Our case indicates that low-dose aspirin could induce SSEH and that conservative treatment with close observation and repeated imaging studies should be considered in cases with neurological improvement or mild deficits.
Aspirin
;
Central Nervous System
;
Hematoma
;
Hematoma, Epidural, Spinal
;
Skin
6.A Comparison of Clinical and Radiological Outcome Between Two-Level Discectomy and One-Level Corpectomy for Cervical Degenerative Disc Disease.
Dong Hyun LEE ; Dae Chul CHO ; Joo Kyoung SUNG
Korean Journal of Spine 2008;5(3):142-147
OBJECTIVE: The clinical and radiographic success of a two-level discectomy and autologous iliac bone fusion with anterior cervical plate fixation (ACDFP) was compared with that of a one-level corpectomy and fusion using a titanium mesh cage (corpectomy) for the treatment of degenerative cervical disc disease. METHODS: From January 2004 to December 2007, there were 45 consecutive cases of two disc level degenerative cervical disc disease treated with either ACDFP or corpectomy. The medical records and radiological studies were reviewed, retrospectively. The clinical outcomes were measured using Odom's criteria. The radiologic assessment was performed using images showing the lordosis and bony fusion. RESULTS: Twenty-seven patients were treated with ACDFP. Eighteen patients were treated with corpectomy. The clinical outcome was excellent or good in 25 cases (93%) and 17 cases (94%) treated with ACDFP and corpectomy, respectively. The fusion rate was 96% and 94% for ACDFP and corpectomy, respectively. There was a slight increase in the cervical lordosis in both groups, but there was no significant difference between the 2 groups. There were no irriversible complications in both groups. Reversible complications were encountered in 1 case of corpectomy, and 7 cases of ACDFP, which were mainly associated with donor site. CONCLUSION: Either a ACDFP or a corpectomy provides good clinical outcome and similar bone fusion rates for degenerative disc diseases. However, absence of donor site complications makes a corpectomy better than ACDFP.
Animals
;
Diskectomy
;
Humans
;
Lordosis
;
Medical Records
;
Retrospective Studies
;
Tissue Donors
;
Titanium
7.Synovial Hemangioma Mimicking a Meniscal Cyst of the Knee
Kyoung-Dae MIN ; Whi-Je CHO ; Joo-Young CHA
The Journal of the Korean Orthopaedic Association 2022;57(4):351-355
Synovial hemangioma is a vascular malformation that usually involves the knee. This paper presents the diagnostic ultrasound findings of a synovial hemangioma that could be mistaken for a medial meniscus cyst in a 37-year-old man and report the clinical result of the meniscal repair after an open excision.
8.Comparison of Health Related Quality of Life between Type I and Type II Narcolepsy Patients.
Jae Wook CHO ; Dae Jin KIM ; Kyoung Ha NOH ; Junhee HAN ; Dae Soo JUNG
Journal of Sleep Medicine 2016;13(2):46-52
OBJECTIVES: Narcolepsy with cataplexy is a rare chronic sleep disorder characterized by excessive daytime sleepiness, cataplexy, sleep paralysis, and hypnagogic/hypnopompic hallucinations. The aims of the present study were comparing the health-related quality of life (HR-QOL) of patients with type I and type II narcolepy patients, and determining the factors that influence the HR-QOL in narcolepsy patients. METHODS: All patients performed night polysomnography (PSG) and multiple sleep latency test (MSLT). HR-QOL and the severity of subjective symptoms were evaluated using various questionnaires, including the Korean versions of the Medical Outcome Study Short Form-36, the Pittsburg Sleep Quality Index-Korean version, the Korean version Epworth Sleepiness Scale, and the Korean version Beck Depression Inventory-2. RESULTS: We enrolled 21 type I narcolepsy patients and 27 type II patients. Type I patients had short rapid eye movement (REM) latency on night PSG and more sleep onset REM periods on MSLT. The total score of HR-QOL was worse in patients with type I narcolepsy than in the type II narcolepsy patients. There was association between the severities of excessive daytime sleepiness, depression and the degree of worsening of QOL. CSF hypocretin level had no correlation with the scores of HR-QOL. CONCLUSIONS: These findings demonstrate that type I narcolepsy patients are sleepier, depressive, and have more burden on the HR-QOL. And the impairment in QOL of narcolepsy patients is related to the degree of excessive daytime and depressive mood.
Cataplexy
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Depression
;
Hallucinations
;
Humans
;
Narcolepsy*
;
Outcome Assessment (Health Care)
;
Polysomnography
;
Quality of Life*
;
Sleep Paralysis
;
Sleep Wake Disorders
;
Sleep, REM
9.Histomorphometric Analysis of the Spine and Femur in Ovariectomized Rats Using Micro-Computed Tomographic Scan.
Yong Hwan SHIN ; Dae Chul CHO ; Song Hee YU ; Kyoung Tae KIM ; Hee Jung CHO ; Joo Kyung SUNG
Journal of Korean Neurosurgical Society 2012;52(1):1-6
OBJECTIVE: The purpose of this study was to evaluate the different patterns of bone loss between the lumbar spine and the femur after ovariectomy in rats. METHODS: Twenty-four female Sprague-Dawley rats underwent a sham operation (the sham group) or bilateral ovariectomy (the ovariectomized group). Four and eight weeks after operation, six rats from each of the two groups were euthanized. Serum biochemical markers of bone turnover including osteocalcin and alkaline phosphatase (ALP), which are sensitive biochemical markers of bone formation, and the telopeptide fragment of type I collagen C-terminus (CTX), which is a sensitive biochemical marker of bone resorption, were analyzed. Bone histomorphometric parameters of the 4th lumbar vertebrae and femur were determined by micro-computed tomography. RESULTS: Ovariectomized rats were found to have higher osteocalcin, ALP and CTX levels than sham controls. Additionally, 8 weeks after ovariectomy in the OVX group, serum levels of osteocalcin, ALP and CTX were significantly higher than those of 4 weeks after ovariectomy. Bone loss after ovariectomy was more extensive in the 4th lumbar spine compared to the femur. Bone loss in the 4th lumbar spine was mainly caused by trabecular thinning, but in the femur, it was mainly caused by trabecular elimination. CONCLUSION: The present study demonstrates different patterns of bone loss between the 4th lumbar spine and the femur in ovariectomized rats. Therefore, when considering animal models of osteoporosis, it is important that bone sites should be taken into account.
Alkaline Phosphatase
;
Animals
;
Biomarkers
;
Bone Resorption
;
Collagen Type I
;
Female
;
Femur
;
Humans
;
Lumbar Vertebrae
;
Models, Animal
;
Osteocalcin
;
Osteogenesis
;
Osteoporosis
;
Ovariectomy
;
Rats
;
Rats, Sprague-Dawley
;
Salicylamides
;
Spine
10.Expression of M llerian Inhibiting Substance in Cryptorchidism at the Descending Level of Testis.
Choong Bum LEE ; Kyoung Joon LEE ; Yong Hyung CHO ; Dae Haeng CHO ; Moon Soo YOON
Korean Journal of Urology 1998;39(2):167-172
PURPOSE: To investigate the relationship of MIS and cryptorchidism according to the descending level of testis into scrotum, we studied expression degree of MIS by immunohistochemical analysis using anti-human MIS polyclonal antibody in testicular specimen. MATERIALS AND METHODS: MIS were stained in excised testis by trauma on each 8 patients as control group and age-matched abdominal, inguinal and prepubic cryptorchidism. The expression were classified as score 1, 2, 3 and 4 according to stained degree of percentage in randomized 16 fields(x400) under the light microscope. RESULTS: Of the degree of MIS expression in control group, 87.5% were category 3 or more. The mean score was 3.13+/-0.62. 2. Of the degree of MIS expression in abdominal type cryptorchid testis group that underwent orchiectomies, 68.7% were category 1. The mean score, 1.31 +/- 0.48, showed significant difference compared to control group(p<0.05). 3. Of the degree of MIS expression in inguinal type,56.2% were category 3 or more. The mean score, 2.63+/- 0.81, showed no significant difference compared to control group(p>0.05). 4. Of the degree of MIS expression in prepubic type, 75.0% were category 3 or more. And the mean score, 2.88+/-0.62, showed no significant difference compared to control group(p>0.05). CONCLUSIONS: Expression of MIS is different according to descending level of testis and may play a role in physiologic changes of testicular descent.
Cryptorchidism*
;
Humans
;
Male
;
Orchiectomy
;
Scrotum
;
Testis*