1.Value of the Left Portal Vein Angle (LPVA) on CT for the Diagnosis of Liver Cirrhosis: Comparison with the Caudateto Right Lobe (C/RL) Ratio.
Byung Ihn CHOI ; Joon Koo HAN ; Kyung Mo YEON ; Yoong Ki JEONG ; Hong Dae KIM
Journal of the Korean Radiological Society 1995;32(5):737-742
PURPOSE: To verify the usefulness of left portal vein angle (LPVA) on CT scan in the diagnosis of liver cirrhosis and to compare its diagnostic value with that of caudate to right lobe ratio (C/RL ratio). MATERIALS AND METHODS: LPVA, an angle formed by a vertical line and a line connecting the center of the vertebral body to the umbilical point of the left portal vein, and C/RL ratio were measured on CT scans of 100 cirrhotic and 100 normal livers. Diagnostic values of LPVA and C/RL ratio were compared statistically. RESULTS: The mean of LPVA was 18.9 degrees(SD; 7.6) for normal livers and 25.8 degreesSD; 8.4) for cirrhotic livers (P<0.001). The mean of C/RL ratio was 0.47(SD; 1.10) for normal livers and 0.58(SD;0.14) for cirrhotic livers (P<0.001). When LPVA was greater than 30 degreesliver cirrhosis was diagnosed with 36% sensitivity and 92% specificity. When C/RL ratio was greater than 0.60, the diagnose of liver cirrhosis was with 41% sensitivity and 90% specificity. There was no significant difference of the diagnostic accuracy between LPVA and C/R L ratio in ROC analysis. CONCLUSION: Both LPVA and C/RL ratio are useful diagnostic indices of liver cirrhosis on CTscan. LPVA is more convenient to measure than C/RL ratio.
Diagnosis*
;
Fibrosis
;
Liver Cirrhosis*
;
Liver*
;
Portal Vein*
;
ROC Curve
;
Sensitivity and Specificity
;
Tomography, X-Ray Computed
2.A Case of Lichen Spinulosus with an Histologic Finding of Follicular Mucinosis.
Dae Heon OH ; Kyoung Tae PARK ; Jeong Soo KIM ; Hee Joon YU
Annals of Dermatology 2005;17(2):79-82
No abstract available.
Lichens*
;
Mucinosis, Follicular*
3.A Case of Becker's Nevus Associated with Smooth Muscle Hamartoma.
Hong Seong JEONG ; Chul Ho YOO ; Dae Gyoo BYUN ; Joon Mo YANG ; Yu Sin LEE
Korean Journal of Dermatology 1987;25(6):832-836
We report a case of Becker's nevus associated with smooth muscle hamartoma, in a 21-year-old male patient, which shows clinically match-head sized, flat topped, round to oval, grouped papules with hairs on the outer surface of the right arm, and microscopically reveals numerous bundles of smooth muscle fiber in the dermis.
Arm
;
Dermis
;
Hair
;
Hamartoma*
;
Humans
;
Male
;
Muscle, Smooth*
;
Nevus*
;
Young Adult
4.ANALYSIS OF ARTICLES PUBLISHED IN THE JOURNAL OF THE KOREAN SOCIETY OF EMERGENCY MEDICINE.
Dae Kon SHON ; Keun Jeong SONG ; Seok Joon JANG ; Han Shick LEE
Journal of the Korean Society of Emergency Medicine 1997;8(1):24-30
To raise the quality of research, medical articles which are feasible and objective must be continuously published and be continuously monitored. All articles published in the Journal of the Korean Society of Emergency Medicine from November, 1990 to November, 1995 were compared with a foreign emergency medical journal, the American Journal of Emergency Medicine(AJE). Classifying the articles in the Journal of the Korean Society of Emergency Medicine, there were 15 (8.4%) review articles, 145 (81.0%) original articles and 19 (10.6%) case reports. In the AJE, there were 103 (15.1%) review articles, 304 (44.4%) original articles and 277 (40.5%) case reports. Classifying the original articles in the Journal of the Korean Society of Emergency Medicine, there were 13 (9.0%) experimental articles, 88 (60.7%) descriptive articles and 44 (30.3%) analytic articles. In the AJE, there were 40 (13.2%) experimental articles, 59 (19.4%) descriptive articles and 205 (67.4%) analytic articles. The classification of original articles according to frequency in the Journal of the Korean Society of Emergency Medicine is trauma, resuscitation, toxicology and medical emergency, where as the AJE is medical emergency, trauma, toxicology and EMS. For statistical methods used in original articles, 90 (62.1%) case did not do any statistical analysis or where only descriptive statistics were used. In 6 (4.1%) cases the statistical level was described but statistical methods were nonmentioned. By simple classification study, there were 44 (30.3%) cases of original articles in the Journal of the Korean Society of Emergency Medicine, and 6 (2.0%) cases in the AJE. Because the development of Emergency Medicine as a special department is based on logical articles, organization of articles have study design, make hypothesis, sample gathering, statistical analysis and feasibility of conclusion. For this, the emergency training course needs a course on research methodology.
Classification
;
Emergencies*
;
Emergency Medicine*
;
Logic
;
Research Design
;
Resuscitation
;
Toxicology
5.Nonobstructive Right Retrocaval Ureter Associated with Double Inferior Vena Cava.
Jong Seon YOON ; Dae Jin JEONG ; Hye Su PARK ; Joon RHO ; Do Young PARK ; Chul Seong KIM ; Dae Soo CHANG
Korean Journal of Urology 1997;38(1):106-109
Retrocaval ureter is a rare congenital anomaly. We experienced a case of retrocaval ureter with double inferior vena cava and with intermittent right flank pain in 54 years old female. We performed IVU, RGP, Venacavogram, MRI, and diuretic DTPA renal scan. MRI is the best single study to delineate the anatomy clearly and noninvasively. She was treated with conservative treatment.
Female
;
Flank Pain
;
Humans
;
Magnetic Resonance Imaging
;
Middle Aged
;
Pentetic Acid
;
Retrocaval Ureter*
;
Vena Cava, Inferior*
6.Intrahepatic Extramedullary Hematopoiesis Mimicking a Hypervascular Hepatic Neoplasm on Dynamic- and SPIO-Enhanced MRI.
In Joon LEE ; Se Hyung KIM ; Dae Sik KIM ; Jeong Min LEE ; Joon Koo HAN ; Byung Ihn CHOI
Korean Journal of Radiology 2008;9(Suppl):S34-S38
We present a rare case of a focal intrahepatic extramedullary hematopoiesis (EMH) that mimicked a hypervascular hepatic neoplasm in a 33-year-old woman with idiopathic myelofibrosis. The lesion showed homogeneous and persistent enhancement on both contrast-enhanced CT and gadolinium-enhanced dynamic MR imaging. The lesion did not demonstrate an apparent signal drop on a T2*-weighted sequence following administration of a superparamagnetic iron-oxide agent (SHU 555A). A hepatocellular adenoma was the initial radiological diagnosis. To the best of our knowledge, this is the first report of a histopathologically proven intrahepatic EMH evaluated with dynamic- and SPIO-enhanced MRI.
Adenoma/*diagnosis
;
Adult
;
Diagnosis, Differential
;
*Hematopoiesis, Extramedullary
;
Humans
;
Liver/*physiology
;
Liver Neoplasms/*diagnosis
;
*Magnetic Resonance Imaging
;
Male
;
Primary Myelofibrosis/physiopathology
7.A case of subcapsular splenic hematoma complicated by alcoholic pancreatitis, improved with conservative care.
Hee Jung KIM ; Dae Joon JEONG ; Myeong Ok PARK ; Sung Joon LEE ; Chang Don KANG ; Dae Hee CHOI
Korean Journal of Medicine 2010;79(6):681-685
Splenic complications may occur during the course of pancreatitis, as the pancreas and spleen lie adjacent to each other. However, splenic complications associated with pancreatitis are rare, including splenic vein thrombosis, arterial pseudoaneurysm, subcapsular splenic hematoma, and splenic rupture. The management for subcapsular splenic hematoma with pancreatitis remains controversial. We report a case of a 51-year-old man with alcoholic pancreatitis and the rare complication of a large subcapsular splenic hematoma, which was managed conservatively with a good outcome.
Alcoholics
;
Aneurysm, False
;
Hematoma
;
Humans
;
Middle Aged
;
Pancreas
;
Pancreatitis
;
Pancreatitis, Alcoholic
;
Spleen
;
Splenic Rupture
;
Splenic Vein
;
Thrombosis
8.Efficacy and Safety Evaluation of Tacrolimus-Eluting Stent in a Porcine Coronary Artery Model
Dae Sung PARK ; Mi Hyang NA ; Myung Ho JEONG ; Doo Sun SIM ; Yu Jeong JIN ; Hae Jin KEE ; Mun Ki KIM ; Jeong Ha KIM ; Young Joon HONG ; Kyung Hoon CHO ; Dae Young HYUN ; Seok OH ; Kyung Seob LIM ; Dae-Heung BYEON ; Jeong Hun KIM
Tissue Engineering and Regenerative Medicine 2024;21(5):723-735
BACKGROUND:
A drug-eluting stent (DES) is a highly beneficial medical device used to widen or unblock narrowed blood vessels. However, the drugs released by the implantation of DES may hinder the re-endothelialization process, increasing the risk of late thrombosis. We have developed a tacrolimus-eluting stent (TES) that as acts as a potent antiproliferative and immunosuppressive agent, enhancing endothelial regeneration. In addition, we assessed the safety and efficacy of TES through both in vitro and in vivo tests.
METHODS:
Tacrolimus and Poly(lactic-co-glycolic acid) (PLGA) were applied to the metal stent using electrospinning equipment. The surface morphology of the stent was examined before and after coating using a scanning electron microscope (SEM) and energy dispersive X-rays (EDX). The drug release test was conducted through high-performance liquid chromatography (HPLC). Cell proliferation and migration assays were performed using smooth muscle cells (SMC).The stent was then inserted into the porcine coronary artery and monitored for a duration of 4 weeks.
RESULTS:
SEM analysis confirmed that the coating surface was uniform. Furthermore, EDX analysis showed that the surface was coated with both polymer and drug components. The HPCL analysis of TCL at a wavelength of 215 nm revealed that the drug was continuously released over a period of 4 weeks. Smooth muscle cell migration was significantly decreased in the tacrolimus group (54.1% ± 11.90%) compared to the non-treated group (90.1% ± 4.86%). In animal experiments, the stenosis rate was significantly reduced in the TES group (29.6% ± 7.93%) compared to the bare metal stent group (41.3% ± 10.18%). Additionally, the fibrin score was found to be lower in the TES group compared to the group treated with a sirolimus-eluting stent (SES).
CONCLUSION
Similar to SES, TES reduces neointimal proliferation in a porcine coronary artery model, specifically decreasing the fibrins score. Therefore, tacrolimus could be considered a promising drug for reducing restenosis and thrombosis.
9.A Case of Eosinophilia as a Manifestation of Paraneoplastic Syndrome in Non-Small-Cell Lung Cancer.
Hee Jung KIM ; Dae Joon JEONG ; Hui Young LEE ; In Gyu HWANG ; Seo Young SONG
Korean Journal of Medicine 2011;80(1):113-117
Eosinophilia is most frequently associated with asthma, allergic conditions, and parasitic infestation. Eosinophilia can also be associated with many forms of cancer. However, eosinophilia is infrequently associated with solid tumors. We experienced a 73-year-old-woman with eosinophilia as a manifestation of paraneoplastic syndrome that was combined with non-small-cell lung cancer (NSCLC). Initially, she was diagnosed with idiopathic hypereosinophilic syndrome, but was diagnosed with NSCLC 1 month later. Here, we report this case with a brief review of the literature.
Asthma
;
Carcinoma, Non-Small-Cell Lung
;
Eosinophilia
;
Hypereosinophilic Syndrome
;
Lung
;
Lung Neoplasms
;
Paraneoplastic Syndromes
10.A Case of Desmoplastic Trichoepithelioma.
Jeong Soo KIM ; Kyoung Tae PARK ; Dae Hun OH ; Hee Joon YU
Korean Journal of Dermatology 2004;42(9):1198-1200
Desmoplastic trichoepithelioma is a rare benign adnexal tumor of hair follicle origin. Clinically it is solitary, asymptomatic, white or yellowish and the center is frequently depressed, but not ulcerated. The three critical histologic features are narrow strands of tumor cells, keratinous cysts, and desmoplastic stroma. We present a case of desmoplastic trichoepithelioma in a 61-year-old man who had an asymptomatic, firm, annular nodule with a depressed center and an elevated border on the nose.
Hair Follicle
;
Humans
;
Middle Aged
;
Nose
;
Ulcer