1.Clinical Experience of Automated Percutaneous Lumbar Discectomy.
Won Sik CHOY ; Whan Jeung KIM ; Nam Hun KIM ; Kyu Hyun KIM ; Dae Hwa SONG
Journal of Korean Society of Spine Surgery 1997;4(1):149-156
No abstract available.
Diskectomy*
2.IL-12 and TNF-alpha productions from human peripheral blood mononuclear cells in untreated patients with active pulmonary tuberculosis stimulated with 30-kDa or TSP antigen of Mycobacterium tuberculosis H37Rv.
Chang Hwa SONG ; Eun Kyeong JO ; Dae Su KIM ; Hwa Jung KIM ; Jae Hyun LIM ; Un Ok KIM ; Tae Hyun PAIK ; Jeong Kyu PARK
Immune Network 2001;1(3):250-259
No abstract available.
Humans*
;
Interleukin-12*
;
Mycobacterium tuberculosis*
;
Mycobacterium*
;
Tuberculosis, Pulmonary*
;
Tumor Necrosis Factor-alpha*
3.A Case of Hypersomnolence with Subclinical Hypothyroidism Treated with Levothyroxine.
Minkyeong KIM ; Song Hwa CHAE ; Eun Hye OH ; Baik Kyun KIM ; Dae Jin KIM ; Jae Wook CHO
Journal of Sleep Medicine 2015;12(1):23-25
We present a patient who complained of excessive daytime sleepiness (EDS), which started three years ago. She had no other medical, neurological, and psychiatric disorders. Nocturnal polysomnography did not indicate any sleep disorders, which might cause daytime EDS, such as obstructive sleep apnea. The following multiple sleep latency test was not compatible for narcolepsy. Her laboratory findings were remarkable for subclinical hypothyroidism, although free T4 and T3 were within reference rage, she had elevated thyroid stimulating hormone. After four weeks of levothyroxine treatment, her EDS resolved. The hypersomnolence, as a presenting symptom of subclinical hypothyroidism, was optimally treated after thyroid hormone replacement.
Disorders of Excessive Somnolence*
;
Humans
;
Hypothyroidism*
;
Narcolepsy
;
Polysomnography
;
Rage
;
Sleep Apnea, Obstructive
;
Sleep Wake Disorders
;
Thyroid Gland
;
Thyrotropin
;
Thyroxine*
4.An Isolated Relapse of Acute Lymphoblastic Leukemia as a Chest Wall Mass.
Jee Yeon LEE ; Dae Jin SONG ; Chan Ook WOO ; Jung Hwa LEE ; Kwang Chul LEE
Korean Journal of Pediatric Hematology-Oncology 2002;9(1):117-121
Extramedullary relapse of childhood acute lymphoblastic leukemia (ALL) occurs most commonly in the central nervous system or in the testes. Isolated relapse on chest wall as a soft tissue mass is extremely rare in children with ALL. We experenced a 12-year-old girl who developed an isolated relapse on chest wall during the treatment for ALL. She had a pain and protruding mass on right anterior chest wall 6 months after the initial diagnosis of ALL. Imaging study revealed an 5 7 cm sized soft tissue mass on the right chest wall. Histopathologic examination revealed infiltrates composed of immature lymphoblasts with morphology identical with that of previous bone marrow aspiration. Studies on bone marrow and cerebrospinal fluid were negative for disease at this time. The patient was treated with 3,000 cGy of local irradiation in 10 fractions and systemic chemotherapy with ifosfamide and etoposide. The mass size decreased markedly, but she has been suffering from development of multiple mass in other site and recurrent pleural effusion.
Bone Marrow
;
Central Nervous System
;
Cerebrospinal Fluid
;
Child
;
Diagnosis
;
Drug Therapy
;
Etoposide
;
Female
;
Humans
;
Ifosfamide
;
Pleural Effusion
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma*
;
Recurrence*
;
Testis
;
Thoracic Wall*
;
Thorax*
5.Ross Syndrome with Segmental Anhidrosis and Anisocoria: Application of Finger Winkle Test.
Song Hwa CHAE ; Ji Yoon KIM ; Dae Seong KIM ; Jin Hong SHIN
Journal of the Korean Neurological Association 2016;34(1):57-61
Ross syndrome is characterized by a triad of segmental anhidrosis, tonic pupil, and generalized areflexia. Selective postganglionic autonomic denervation could be the differential diagnostic point for other diseases of the autonomic nervous system. Here we report a patient with regional anhidrosis in his left hand and sole, and anisocoria. An evaluation of sweating and the pupillary response together with generalized areflexia confirmed the diagnosis of Ross syndrome. The finger wrinkle test is a simple and useful tool for revealing segmental sympathetic denervation.
Anisocoria*
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Autonomic Denervation
;
Autonomic Nervous System
;
Diagnosis
;
Fingers*
;
Hand
;
Humans
;
Hypohidrosis*
;
Sweat
;
Sweating
;
Sympathectomy
;
Tonic Pupil
6.Chronic Spinal Epidural Hematoma due to Repeated Epidural Block: A Case Report.
Hyun Min OH ; Hwa Seung PARK ; Dong Youl RHEE ; Jun Sook SONG ; Weon HEO ; Dae Neung KIM
Korean Journal of Spine 2008;5(1):29-32
A case of a patient diagnosed as the chronic spinal epidural hematoma in the lumbar region is reported. There was no history of trauma except the repeated epidural block for controlling the lower back pain at the pain clinic. The symptoms were occurred after epidural block and were exaggerated by repeated injections. Magnetic resonance imaging showed a spinal epidural mass located dorsolaterally at the level of L3-L4. After removal of the hematoma, the symptoms were completely relieved. The diagnosis of a chronic spinal epidural hematoma was confirmed with both operative and histological findings.
Hematoma
;
Hematoma, Epidural, Spinal
;
Humans
;
Low Back Pain
;
Lumbosacral Region
;
Magnetic Resonance Imaging
;
Pain Clinics
7.Influence of Obstructive Sleep Apnea on Systemic Blood Pressure, Cardiac Rhythm and the Changes of Urinary Catecholamines Concentration.
Dae Keun LO ; Young Mee CHOI ; Jeong Sup SONG ; Sung Hak PARK ; Hwa Sik MOON
Tuberculosis and Respiratory Diseases 1998;45(1):153-168
BACKGROUND: The existing data indicate that obstructive sleep apnea syndrome contributes to the development of cardiovascular dysfunction such as systemic hypertension and cardiac arrhythmias, and the cardiovascular dysfunction has a major effect on high long-term mortality rate in obstructive sleep apnea syndrome patients. To a large extent the various studies have helped to clarify the pathophysiology of obstructive sleep apnea, but many basic questions still remain unanswered. METHOD: In this study, the influence of obstructive sleep apnea on systemic blood pressure, cardiac rhythm and urinary catecholamines concentration was evaluated. Over-night polysomnography, 24-hour ambulatory blood pressure and EGG monitoring, and measurement of urinary catecholamines, norepinephrine (UNE) and epinephrine (UEP), during waking and sleep were undertaken in obstructive sleep apnea syndrome patients group (OSAS, n=29) and control group (Gontrol, n=25). RESULTS: 1) In OSAS and Control, UNE and UEP concentrations during sleep were significantly lower than during waking (P<0.01). In UNE concentrations during sleep, OSAS showed higher levels compare to Control (P<0.05). 2) In OSAS, there was a increasing tendency of the number of non-dipper of nocturnal blood pressure compare to Control (P=0.089). 3) In both group (n=54), mean systolic blood pressure during waking and sleep showed significant correlation with polysomnographic data including apnea index (Al), apnea-hypopnea index (AHI), arterial oxygen saturation nadir (SaO2 nadir) and degree of oxygen desaturation (DOD). And UNE concentrations during sleep were correlated with Al, AHI, SaO2 nadir, DOD and mean diastolic blood pressure during sleep. 4) In OSAS with AI>20 (n=14), there was a significant difference of heart rates before, during and after apneic events (P<0.01), and these changes of heart rates were correlated with the duration of apnea (P<0.01). The difference of heart rates between apneic and postapneic period (deltaHR) was significantly correlated with the difference of arterial oxygen saturation between before and after apneic event (deltaSaO2) (r=0.223, P<0.001). 5) There was no significant difference in the incidence of cardiac arrhythmias between OSAS and Control. In Control, the incidence of ventricular ectopy during sleep was significantly lower than during waking. But in OSAS, there was no difference between during waking and sleep. CONCLUSION: These results suggested that recurrent hypoxia and arousals from sleep in patients with obstructive sleep apnea syndrome may increase sympathetic nervous system activity, and recurrent hypoxia and increased sympathetic nervous system activity could contribute to the development of cardiovascular dysfunction including the changes of systemic blood pressure and cardiac function.
Anoxia
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Apnea
;
Arousal
;
Arrhythmias, Cardiac
;
Blood Pressure*
;
Catecholamines*
;
Epinephrine
;
Heart Rate
;
Humans
;
Hypertension
;
Incidence
;
Mortality
;
Norepinephrine
;
Ovum
;
Oxygen
;
Polysomnography
;
Sleep Apnea, Obstructive*
;
Sympathetic Nervous System
;
United Nations
8.The Effect of Virtual Reality and Tetra-Ataxiometric Posturography Programs on Stroke Patients With Impaired Standing Balance.
Yoon Bum SONG ; Min Ho CHUN ; Won KIM ; Sook Joung LEE ; Jin Hwa YI ; Dae Hwan PARK
Annals of Rehabilitation Medicine 2014;38(2):160-166
OBJECTIVE: To investigate the effect of virtual reality (VR) and a tetra-ataxiometric posturography (Tetrax) program on stroke patients with impaired standing balance. METHODS: Thirty acute stroke patients with impaired standing balance were recruited and randomly assigned to a VR, Tetrax, or control group. All patients received conventional balance training as a baseline; and VR and Tetrax patients received VR or Tetrax treatment, in addition. The primary outcome measures to evaluate the overall standing balance were the Berg Balance Scale (BBS) and the falling index (FI). The secondary outcome measures were the stability index (SI) and the weight distribution index (WDI), which were used to evaluate the balance status according to specific body positions. The FI, SI, and WDI were measured using the Tetrax instrument. RESULTS: The BBS and FI scores were improved in all groups, with no significant differences between groups. In open-eyed positions, the VR group showed significantly greater improvement in SI and WDI scores than the control group (p<0.017). In closed-eyed positions, the Tetrax group showed significantly greater improvement in SI and WDI scores than the control group (p<0.017). CONCLUSION: The inclusion of VR and Tetrax programs did not lead to an overall benefit in balance. VR and Tetrax did, however, demonstrate a benefit in specific positions. A Tetrax program may benefit patients with abnormal proprioceptive function, whereas a VR program may benefit patients with normal sensory function.
Humans
;
Outcome Assessment (Health Care)
;
Postural Balance
;
Sensation
;
Stroke*
;
Virtual Reality Exposure Therapy
9.The Effect of Virtual Reality and Tetra-Ataxiometric Posturography Programs on Stroke Patients With Impaired Standing Balance.
Yoon Bum SONG ; Min Ho CHUN ; Won KIM ; Sook Joung LEE ; Jin Hwa YI ; Dae Hwan PARK
Annals of Rehabilitation Medicine 2014;38(2):160-166
OBJECTIVE: To investigate the effect of virtual reality (VR) and a tetra-ataxiometric posturography (Tetrax) program on stroke patients with impaired standing balance. METHODS: Thirty acute stroke patients with impaired standing balance were recruited and randomly assigned to a VR, Tetrax, or control group. All patients received conventional balance training as a baseline; and VR and Tetrax patients received VR or Tetrax treatment, in addition. The primary outcome measures to evaluate the overall standing balance were the Berg Balance Scale (BBS) and the falling index (FI). The secondary outcome measures were the stability index (SI) and the weight distribution index (WDI), which were used to evaluate the balance status according to specific body positions. The FI, SI, and WDI were measured using the Tetrax instrument. RESULTS: The BBS and FI scores were improved in all groups, with no significant differences between groups. In open-eyed positions, the VR group showed significantly greater improvement in SI and WDI scores than the control group (p<0.017). In closed-eyed positions, the Tetrax group showed significantly greater improvement in SI and WDI scores than the control group (p<0.017). CONCLUSION: The inclusion of VR and Tetrax programs did not lead to an overall benefit in balance. VR and Tetrax did, however, demonstrate a benefit in specific positions. A Tetrax program may benefit patients with abnormal proprioceptive function, whereas a VR program may benefit patients with normal sensory function.
Humans
;
Outcome Assessment (Health Care)
;
Postural Balance
;
Sensation
;
Stroke*
;
Virtual Reality Exposure Therapy
10.Right Cerebellopontine Angle Tumor Localized by Blink Reflex Abnormality.
Song Hwa CHAE ; Jin Hong SHIN ; Sun Ki SUNG ; Dae Seong KIM
Journal of the Korean Neurological Association 2016;34(1):86-87
No abstract available.
Blinking*
;
Cerebellopontine Angle*
;
Neuroma, Acoustic*