1.Familial Occurrence of Moyamoya Disease: Report of Two Families.
Sang Hwa KIM ; Nam Je KANG ; Dae Seong KIM ; Dae Soo JEONG ; Kyu Hyun PARK ; Chang Hwa CHOI
Journal of the Korean Neurological Association 1998;16(4):603-606
BACKGROUND: Whether the changes of risk factors (hypertension, diabetes mellitus, smoking, alcohol) can precipitate stroke remains unknown, and antecedent infection and psychologic stress are described inss case-control study, 113 consecutive patients with acute cerebrovascular disease (38 small vessel disease, 43 large vessel disease, 11 cardiogenic infarction, 4 infarction of undetermined cause, and 17 intracerebral hemorrhage) and 23 control subjects were evaluated. Changes of the risk factors (and their management) were interviewed. A sign/symptom based questionnaire was used to characterize the prevalence of recent prior infection and exposure to coldness. Psychologic stress was measured with the use of Social Readjustment Rating Scale. RESULTS: The negative change of alcohol drinking was significantly higher in the stroke group. However, there was no significant difference between stroke and control groups in the changes of thether risk factors. The prevalence of previous (within 1 month) infection was significantly higher in the stroke group compared with control subjects (p=0.03). However, there were no significant differences among the stroke subtypes in the prevalence of infection(p=0.08). Upper respiratory tract infections constituted the most common type of infection. The exposure to coldness was significantly higher in the stroke group compared with control subjects (p=0.002). The level of stress within the prior 1 month/1 year was significantly higher in the stroke group than control group (p=0.01). CONCLUSION: Our data suggest that preceding infection, exposure to coldness, psychologic stress, and the negative change of alcohol drinking may be comm.
Alcohol Drinking
;
Case-Control Studies
;
Diabetes Mellitus
;
Humans
;
Infarction
;
Moyamoya Disease*
;
Prevalence
;
Surveys and Questionnaires
;
Respiratory Tract Infections
;
Risk Factors
;
Smoke
;
Smoking
;
Stress, Psychological
;
Stroke
2.Cavernous Hemangioma of the kidney: Report of a case.
Won Sang PARK ; Young Dae KIM ; Ki Hwa YANG ; Sun Moo KIM
Korean Journal of Pathology 1991;25(4):363-366
Hemangioma of the kidney is a relatively uncommon tumor, which is most commonly located in the tip of the papilla. This lesion is usually small and has been found incidentally at postmorten examination. About 200 cases of renal hemangioma have been reported since Virchow's original report in 1876. In renal hemangioma, cavernous hemangioma is the most common type. They can create diagnostic problem for the clinician and the radiologist. We experienced a case of renal cavernous hemangioma in the medulla of the upper pole. The patient was a twenty-seven-year-old male who had gross hematuria and right flank pain. A nephrectomy was performed. An ill-defined mass, 4.5x3.0x1.5 cm, was observed around the pelvis. Microscopically, the tumor mass was hemangioma of the cavernous type.
Male
;
Humans
;
Hemangioma
3.A study on surface of various abutment screws.
Chan Ik PARK ; Chae Heon CHUNG ; Han Cheol CHOI ; Dae Hwa BACK
The Journal of Korean Academy of Prosthodontics 2003;41(3):351-359
STATEMENT OF PROBLEM: Regardless of any restoration, most of case, we used in screw connection between abutment and implant. For this reason, implant screw loosening has been remained problem in restorative practices. PURPOSE: The purpose of this study was to compare surface of coated/plated screw with titanium and gold alloy screw and to evaluate physical property of coated/plated material after scratch test in FESEM investigation. MATERIAL AND METHODS: GoldTite, titanium screw provided by 3i (Implant Innovation, USA) and TorqTite, titanium screw by Steri-Oss (Nobel Biocare, USA) and gold screw, titanium screw by AVANA (Osstem Implant, korea) - were selected for this study. Each abutment screw surface was observed at 100 times, and then screw crest, root, and slope were done more detailed numerical value, at 1000 times with FESEM. A micro-diamond needle was also prepared for the scratch test. Each abutment screw was fixed, micro-diamond scratch the surface of head region was made at constant load and then was observed central region and periphery of fine trace through 1000 times with FESEM. RESULTS: The surface of GoldTite was smoother than that of other kinds of screw and had abundant ductility and malleability compared with titanium and gold screw. The scratch test also showed that teflon particles were exfoliated easily in screw coated with teflon. Titanium screw had a rough surface and low ductility. CONCLUSION: It was recommended that the clinical use of gold-plated screw would prevent a screw from loosening.
Alloys
;
Head
;
Needles
;
Polytetrafluoroethylene
;
Titanium
4.Chromosomal Aberrations in Ovarian Carcinoma Cell Line, SNU - S , Using Chromosome Painting.
Jae Seong KANG ; Dae Woon KIM ; Yong Hyuck CHUN ; Sun Hwa PARK
Journal of the Korean Cancer Association 2000;32(1):120-128
PURPOSE: The characterization of all recognizable chromosomal rearrangements was dis- turbed by technical limitation of conventional cytogenetic methods. Recently, the strong usefullness of generation of chromosome specific painting probes in identification of marker chromosomes has proven. This study was intended to analyze the chromosomal aberrations in human ovarian cancer cell line, SNU-8, by G-banding and multiple paintings. MATERIALS AND METHODS: Human ovarian cancer cell line, SNU-8 was cultured and harvested for cytogenetic analysis. Routine karyotyping was performed. For complete analysis of chromosomal aberrations, human chromosome-specific painting probes were constructed from somatic hybrid cells. The origins of the unidentified marker chromosomes were analyzed by fluorescent in situ hybridization (FISH) with these painting probes. RESULTS: All chromosome alterations were confirmed by the use of multiple chromosome paintings, which also demonstrated a number of additional alterations. SNU-8 had the karyotype 62-69,XXX, + der(1;10)(q10;p10),der(3;18) (q10;p10)X2,-4,+ 5,+ 7,del(9)(q21)X2,-11,-13,-15,-16,der(17;19)(q10;q10) X2, + 20,-22[cp51]. CONCLUSION: The chromosomal aberrations of SNU-8 cell line was effectively analyzed by FISH with these painting probes, and the approach methods of this study can be applied to cytogenetic analysis of chromosomal aberrations in the other cancers.
Cell Line*
;
Cell Line, Tumor
;
Chromosome Aberrations*
;
Chromosome Painting*
;
Cytogenetic Analysis
;
Cytogenetics
;
Humans
;
Hybrid Cells
;
In Situ Hybridization, Fluorescence
;
Karyotype
;
Karyotyping
;
Ovarian Neoplasms
;
Paint
;
Paintings
5.A Case of Bronchial Obstruction with Mucus Plug following Endotracheal Intubation .
Dae Won PARK ; Chang Soo YOU ; Sang Hwa LEE
Korean Journal of Anesthesiology 1974;7(1):133-136
To keep the patent airway during a general anesthetic procedure or when handling an unconscious patient is the most important concern as well as responsibility and/or duty of the anesthesiologist. Many delicate operations could and can be performed because of the development of anesthetic techniques aad methods, especially through the introduction of endotracheal intubations. However, at times, an endotracheal tube can unfortunately be a hazardous instrument-lethal instead of lifesaving. The authors experienced a case of left main bronchial obstruction with a thick mucus plug immediately following the completion of oro-endotracheal intubation. This was successfully remedied by direct bronchoscopic aspiration under transtracheal spray. In such a circumstance as this, the newly designed instrument, namely; a bronchofiberscope, is a real necessity.
Humans
;
Intubation
;
Intubation, Intratracheal*
;
Mucus*
6.Simple pneumomediastinum showing the findings of pleural effusion.
Sung Jin KIM ; Sung Hwa HONG ; Kil Sun PARK ; Dae Young KIM
Journal of the Korean Radiological Society 1992;28(5):702-704
We experienced a case of simple pneumonediastinum showing the findings of pleural effusion. Frontal chest radiography showed not only pneumomediastinum but also diffuse haziness with sharp medial margin on left lower lung field, blunting of costophrenic angle, and indistinct contour of diaphragm simulating pleural effusion. CT scan confirmed that these findings arose from the displaced pleura and the associated compression atelectasis by loculated air on the anterior mediastinum.
Diaphragm
;
Lung
;
Mediastinal Emphysema*
;
Mediastinum
;
Pleura
;
Pleural Effusion*
;
Pulmonary Atelectasis
;
Radiography
;
Thorax
;
Tomography, X-Ray Computed
7.Digital Biomarkers in Living Labs for Vulnerable and Susceptible Individuals: An Integrative Literature Review
YouHyun PARK ; Tae-Hwa GO ; Se Hwa HONG ; Sung Hwa KIM ; Jae Hun HAN ; Yeongsil KANG ; Dae Ryong KANG
Yonsei Medical Journal 2022;63(S1):43-55
Purpose:
The study aimed to identify which digital biomarkers are collected and which specific devices are used according to vulnerable and susceptible individual characteristics in a living-lab setting.
Materials and Methods:
A literature search, screening, and appraisal process was implemented using the Web of Science, Pubmed, and Embase databases. The search query included a combination of terms related to “digital biomarkers,” “devices that collect digital biomarkers,” and “vulnerable and susceptible groups.” After the screening and appraisal process, a total of 37 relevant articles were obtained.
Results:
In elderly people, the main digital biomarkers measured were values related to physical activity. Most of the studies used sensors. The articles targeting children aimed to predict diseases, and most of them used devices that are simple and can induce some interest, such as wearable device-based smart toys. In those who were disabled, digital biomarkers that measured location-based movement for the purpose of diagnosing disabilities were widely used, and most were measured by easy-to-use devices that did not require detailed explanations. In the disadvantaged, digital biomarkers related to health promotion were measured, and various wearable devices, such as smart bands and headbands were used depending on the purpose and target.
Conclusion
As the digital biomarkers and devices that collect them vary depending on the characteristics of study subjects, researchers should pay attention not only to the purpose of the study but also the characteristics of study subjects when collecting and analyzing digital biomarkers from living labs.
8.Surgical Treatment of Intracranial Arachnoid Cyst by Excision.
Hwa Seung PARK ; Dong Youl RHEE ; Sang Yong KIM ; Sang Nam PARK ; Dae Noung KIM ; Man Su YOU
Journal of Korean Neurosurgical Society 1991;20(10-11):847-853
Arachnoid cysts are benign developmental cysts that occur between aachnoid layers, which represent approximately 1 percent of all intracranial space-occupying lesions, their most common location being the middle cranial fossa. Current surgical treatment options for intracranial arachnoid cyst are either craniotomy and excision of cyst or shunting of cyst contents extracranially. We treated 10 cases of intracranial arachnoid cyst by excision during last two years. For the best surgical curability, we have, not only removed the cyst wall and adhesive gliotic tissue as possible, but also made the opening to basal cistern for communication. During average 8.4 months follow up, we observed, not specific morbidity and mortality, but good clinical improvement and brain expansion. As above result, if haven't specific problem, the direct surgical removal may be the primary choice for intracranial arachnoid cyst, especially in children with noncommunicating type in sylvian.
Adhesives
;
Arachnoid Cysts*
;
Brain
;
Child
;
Cranial Fossa, Middle
;
Craniotomy
;
Follow-Up Studies
;
Humans
;
Mortality
9.IL-12 and TNF-alpha productions from human peripheral blood mononuclear cells in untreated patients with active pulmonary tuberculosis stimulated with 30-kDa or TSP antigen of Mycobacterium tuberculosis H37Rv.
Chang Hwa SONG ; Eun Kyeong JO ; Dae Su KIM ; Hwa Jung KIM ; Jae Hyun LIM ; Un Ok KIM ; Tae Hyun PAIK ; Jeong Kyu PARK
Immune Network 2001;1(3):250-259
No abstract available.
Humans*
;
Interleukin-12*
;
Mycobacterium tuberculosis*
;
Mycobacterium*
;
Tuberculosis, Pulmonary*
;
Tumor Necrosis Factor-alpha*
10.Successful Removal of Hemangioblastoma Originating in the Medulla Oblongata: Report of 1 Case.
Gi Han BAE ; Jin Hwa EUM ; Dae Jo KIM ; Kwan Hee PARK
Journal of Korean Neurosurgical Society 1995;24(3):331-337
Solid hemangioblastomas of the medulla oblongata are benign vascular neoplasms located in a critical area. We experienced a case of solid hemangioblastoma originated in the medulla oblongata with the syrinx in the cervical spinal cord. Preoperative magnetic resonance imaging provided precise anatomical location and radiologic features of the tumor, which facilitated its total removal. Cardiovascular and pulmonary disorders often complicate this type of surgery, and postoperative dysphagia is a frequent sequelae.
Deglutition Disorders
;
Hemangioblastoma*
;
Magnetic Resonance Imaging
;
Medulla Oblongata*
;
Spinal Cord
;
Vascular Neoplasms