No abstract available.
Humans ; Hypertension* ; Kidney Failure, Chronic* ; Renal Insufficiency*

No abstract available.
Humans ; Hypertension* ; Kidney Failure, Chronic* ; Renal Insufficiency*

An intraosseous epidermal cyst is a rare benign cystic lesion. It is thought to result from congenital factors or trauma and can lead to bone destruction because the cyst develops at the soft tissue around the bone. Radiological findings of intraosseous epidermal cysts are a well-defined radiolucent lesion, with cortical expansion. It is important to differentiate an intraosseous epidermal cyst with other disease developed at distal phalanx because its clinical and radiological findings are similar. We report two rare cases of intraosseous epidermal cysts that developed at the distal phalanx.
Epidermal Cyst*

One hundred cases of anterior communicating artery aneurysms, operated upon during a 10-year period from 1977 to 1987, were analysed to study the microsurgical anatomy of the aneurysms. All of the cases were operated by direct intracranial approach using a operating microscope. Findings of preoperative four-vessel angiogram, operative microphotographs, operative microvideo tapes, and operator's drawings with narratives were investigated on in order to provide the detaild microsurgical anatomy of the aneurysms to obtain the classification according to it. The results were as follows; 1) The anatomical variations of the anterior portion of circle of Willis were as follows;right A1 hypoplasia in 23 cases, left A1 hypoplasia in 9 cases, left A1 aplasia in 3 cases, duplication of anterior communicating artery in 3 cases, and fenestration of anterior communicating artery in 1 case. 2) The diameter of the aneurysm was as follows;5-10mm in 73% below 5mm in 16%, and over 10mm in 11%. 3) Classification of the anterior communicating artery aneurysms according to its direction were as follows;anterior directions in 65%, posterior directions in 16%, superior directions in 10%, inferior direction in 9%. 4) The frequency of hemorrhage were as follows;One bleeding in 65%, Two bleedings in 25%, more than three bleedings in 10%. 5) The vasospasm was observed in 26%, the hydrocephalus in 44%. 6) The posteriorly directing aneurysms showed worse preoperative state than anteriorly directing ones, and the diameter and the direction of anterior communicating artery aneurysm has no relationship with hydrocephalus, vasospasm, and rebleeding. 7) Overall mortality was 5%. Psychotic disturbance, one of the significant complications of rupture of the anterior communicating artery aneurysms, was observed in 13% and among these 6% were observed after operation. Frontal lobe syndrome, organic brain syndrome, depression, confusion, mutism, memory disturbance were manifestations of psychotic disfurbances.
Aneurysm ; Arteries ; Brain ; Circle of Willis ; Classification* ; Depression ; Frontal Lobe ; Hemorrhage ; Hydrocephalus ; Intracranial Aneurysm* ; Memory ; Mortality ; Mutism ; Rupture

BACKGROUND: Cyclosporin A (CsA), a potent immunosuppressant, has been reported to be effective in the treatment of severe atopic dermatitis (AD). OBJECTIVE: The aim of this study was to evaluate the efficacy and side-effects of CsA in Korean patients with severe AD. MATERIALS AND METHODS: 16 patients with recalcitrant AD took CsA for at least 6 weeks. Among them, 11 patients were followed up for more than 16 weeks. Initial dose was 5mg/kg/day (maximum 300 mg/day) and the dose was reduced according to their therapeutic responses. SCORAD (Scoring AD) was used to evaluate clinical efficacy of CsA. During the 1st month of therapy, the therapeutic efficacy and side-effects were evaluated every 2weeks and after 1 month, every month. We checked blood pressure and laboratory abnormalities including liver function test, blood urea nitrogen (BUN), creatinine (Cr) and urinalysis at each visit in addition to observing clinical adverse effects. RESULTS: Significant reduction of SCORAD was noted in 15 patients after 6 weeks of CsA therapy. Only one patient stopped CsA therapy because of the elevation of blood pressure. Three patients showed albuminuria, which disappeared after CsA dose reduction. CONCLUSION: CsA can be used effectively and safely in severe Korean AD patients. Albuminuria seems to be a peculiar side-effect in Korean patients.
Albuminuria ; Blood Pressure ; Blood Urea Nitrogen ; Creatinine ; Cyclosporine* ; Dermatitis, Atopic* ; Humans ; Liver Function Tests ; Urinalysis

No abstract available.
Gemfibrozil* ; Humans ; Peritoneal Dialysis, Continuous Ambulatory*

The hyperimmunoglobulinemia E (Jobs) syndrome (HIES) is characterized by marked elevated levels of IgE, recurrent cutaneous and systemic staphylococcal infections, atopic-like dermatitis, and defective neutrophil chemotaxis. Three cases of HIES have been reported in Korea, but not in the dermatology literature. We report a case of HIES with cutaneous infections and MRSA (methicillin-resistant Staphylococcus aureus). A 15-month-old girl presented with intractable pruritic excoriated papular pustular skin lesions and multiple subcutaneous abscesses. Surgical drainage of the abscesses and a course of antibiotic treatment in addition to topical steroids for about 7 weeks resulted in a remarkable improvement.
Abscess ; Chemotaxis ; Dermatitis ; Dermatology ; Drainage ; Female ; Humans ; Hypergammaglobulinemia* ; Immunoglobulin E ; Infant ; Job Syndrome* ; Korea ; Methicillin-Resistant Staphylococcus aureus ; Neutrophils ; Skin ; Staphylococcal Infections ; Staphylococcus ; Steroids

No abstract available.
Muscular Dystrophy, Oculopharyngeal*

20-40% of cases of acute transverse myelitis are attributed to viral infections, although the specific viral etiology is only rarely identified. We have studied one patient with transverse myelitis in association with acute hepatitis B virus infection. Hepatitis virus should be considered as rare cause of transverse myelitis.
Hepatitis B virus* ; Hepatitis B* ; Hepatitis Viruses ; Hepatitis* ; Humans ; Myelitis, Transverse*

No abstract available.
Gonadotropin-Releasing Hormone* ; Gonads* ; Steroids* ; Trophoblasts*