1.Electron Microscopic Study in the Rat Model of Electrically Injured Myelopathy: Preliminary Report
Je Hoon JEONG ; Cheong Hoon SEO ; Dae Hoon LEE
Korean Journal of Neurotrauma 2023;19(2):218-226
Objective:
The patient with electrically injured myelopathy showed mild motor weakness without somatosensory pathway abnormalities. Few reports have been reported on the pathophysiological mechanisms of electrically injured myelopathy, and there is controversy about the exact pathological causes. This study aimed to investigate the ultrastructural changes in the electron microscopic findings of electrical spinal cord injury.
Methods:
Nine rats were used in this study. We performed 7 electrical shocks (frequency, 120 Hz; pulse width, 0.9 ms; duration, 3 seconds; current, 99 mA) using an electroconvulsive therapy (ECT) apparatus (57800 ECT unit; UGO BASILE). We used one ear and one contralateral hind limb as entry and exit sites, respectively. We only enrolled rats with hind limb weakness and performed electron microscopy evaluations of the spinal cord on the first day and 4 weeks after injury.
Results:
On the first day after injury, an electron microscopic examination showed a directly damaged area that appeared to be torn as physical damage, damaged myelin sheath, vacuolated axons in the myelin sheath, swollen Golgi apparatus, and injured mitochondria.Looking at changes in motor and sensory nerves, the sensory neurons showed recovered mitochondria and Golgi apparatus 4 weeks after injury; however, motor neurons still showed injured mitochondria, swollen Golgi apparatus, and endoplasmic reticulum.
Conclusion
This study showed that recovery from ultrastructural injury was more rapid in sensory neurons than in motor neurons.
2.Immediate reconstruction of thumb tip injury.
Gyu Ho CHA ; Sang Hyun WOO ; Dae Hoon LEE ; Jeong Hyun SEUL
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1991;18(3):533-538
No abstract available.
Thumb*
3.A Case of Retrocaval Ureter.
Jeong Hoon LEE ; Dae Haeng CHO
Korean Journal of Urology 1984;25(2):230-232
This rare venous congenital anomaly has been diagnosed preoperatively in a 35-year-old female with complaint of the right flank pain. Herein a case of retrocaval ureter is presented with brief review of literatures.
Adult
;
Female
;
Flank Pain
;
Humans
;
Retrocaval Ureter*
4.A comparison of ritodrine hydrochloride(Yutopar@) and nifedipine in the treatment of preterm labor.
Jeong Seung LEE ; Jang Heub KIM ; Do Kang KIM ; Dae Hoon KIM ; Hun Young LEE
Korean Journal of Obstetrics and Gynecology 1991;34(3):340-347
No abstract available.
Female
;
Nifedipine*
;
Obstetric Labor, Premature*
;
Pregnancy
;
Ritodrine*
5.Twa Cases of Sacrococcygeal Teratoma Doagnosed by prenatal Ultrasosography.
Dae Hoon JEONG ; Jeong Soo KIM ; Young Nam KIM ; Woo Gyeong KIM ; Moon Su SUNG ; Hyun Chan KIM
Korean Journal of Perinatology 2000;11(3):360-365
No abstract available.
Teratoma*
6.A case of Endobronchial Tuberculosis Accompanied by Embedded Lymph Node.
Kyoung Hoon CHOI ; Jeong A HWANG ; Byeung Ju JEONG ; Kyu Earn KIM ; Ki Young LEE ; Fan Chen MONG ; Hee Dae PARK
Journal of the Korean Pediatric Society 1990;33(3):386-392
No abstract available.
Lymph Nodes*
;
Tuberculosis*
7.Effects of ProSeal Laryngeal Mask Airway on Intraoperative Ventilation and Blood Pressure, and Postoperative Sore Throat in Laparoscopic Cholecystectomy.
Ji Hoon JEONG ; Sun Ok SONG ; Heung Dae KIM
Korean Journal of Anesthesiology 2004;46(1):10-16
BACKGROUND: This study was performed to evaluate the effects of a ProSeal laryngeal mask airway (PLMA) on intraoperative ventilation and blood pressure, and postoperative sore throat in laparoscopic cholecystectomy (LC). METHODS: Sixty, ASA 1 or 2 adults scheduled for elective LC were randomly allocated into two groups; i.e., endotracheal tube (ETT) or PLMA groups. General anesthesia was administered in the usual fashion. Blood pressure and heart rate were measured before and after the induction of anesthesia. Blood pressure, heart rate, peak inspiratory pressure (PIP) and end-tidal CO2 (ETCO2) also were measured before and after intraabdominal CO2 insufflation (pneumoperitoneum) at 5 minutes intervals over 30 minutes. Sore throat, nausea and vomiting were evaluated at 6 and 24 hours postoperatively. RESULTS: Blood pressure and heart rate were higher in the ETT group than in the PLMA group after induction (P < 0.05), however, no differences were observed during pneumoperitoneum. Following the induction of pneumoperitoneum, ETCO2 increased significantly, but without the group differences. PIP was less increased in the PLMA group. No significant differences were observed in incidences of postoperative sore throat, nausea or vomiting in the two groups. CONCLUSIONS: We conclude that PLMA is a useful alternative to ETT in LC. Furthermore, PLMA seems to be more useful for hypertensive patients.
Adult
;
Anesthesia
;
Anesthesia, General
;
Blood Pressure*
;
Cholecystectomy, Laparoscopic*
;
Heart Rate
;
Humans
;
Incidence
;
Insufflation
;
Laryngeal Masks*
;
Nausea
;
Pharyngitis*
;
Pneumoperitoneum
;
Ventilation*
;
Vomiting
8.Association Studies of the CT Repeat Polymorphism in the Cholecystokinin B Receptor Gene with the Diagnosis and the Response of Pharmacotherapy in Korean Patients with Panic Disorder.
Young Hee CHOI ; Jong Min WOO ; Jeong Hoon BAE ; Dae Yeon CHO ; Won KIM
Korean Journal of Psychopharmacology 2006;17(1):60-69
OBJECTIVE: This study aimed to test the possible association between Cholecystokinin B receptor (CCKBR) promoter gene and panic disorder. METHODS: 262 patients with panic disorder and 76 healthy controls participated in this study. Genotyping was performed by polymerase chain reaction-based method. RESULTS: Allele distribution of CT repeat polymorphism in patients with panic disorder was not different from those of the controls. However, after excluding the patients with panic disorder comorbid with major depressive disorder and other anxiety disorder, we found out the significant association of CCKBR (CT)n repeat with the panic disorder without comorbidities. And we analysed the data as a di-allelic polymorphism with a short (140-162 bp) and a long (164-180 bp) allele. In the di-allelic analysis, there was an excess of the shorter allele in patients with panic disorder. CONCLUSION: The present study suggested that the CCKBR promoter dinucleotide polymorphism may have a potential role for susceptibility to panic disorder in the Korean population and thus calls for consecutive studies in order to pile up the data with larger different ethnic background.
Alleles
;
Anxiety Disorders
;
Cholecystokinin*
;
Comorbidity
;
Depressive Disorder, Major
;
Diagnosis*
;
Drug Therapy*
;
Humans
;
Panic Disorder*
;
Panic*
;
Receptor, Cholecystokinin B*
9.Giant Synovial Chondromatosis of the Knee Mimicking a Parosteal Osteosarcoma: A Case Report.
Chang Ho KANG ; Jong Hoon PARK ; Dae Hee LEE ; Chul Hwan KIM ; Jeong Mi PARK ; Won Seok LEE
The Journal of the Korean Bone and Joint Tumor Society 2010;16(2):95-98
Synovial chondromatosis is a benign nodular cartilaginous proliferation arising in the synovium of joints. The radiolographic features of this condition are variable. Rarely, it would be confused with malignancy such as chondrosarcoma, osteosarcoma or synovial sarcoma. We report a case of primary synovial chondromatosis of the posterior aspect of the proximal tibia mimicking a parosteal osteoarcoma on the radiography, which showed a homogeneously radiopaque juxtacortical mass. However, subsequent computed tomography (CT) showed multiple intra-articular masses containing chondroid mineralization, suggesting synovial chondromatosis.
Chondromatosis, Synovial
;
Chondrosarcoma
;
Diagnostic Imaging
;
Joints
;
Knee
;
Osteosarcoma
;
Sarcoma, Synovial
;
Synovial Membrane
;
Tibia
10.A Case of Myotonic Dystrophy with Prolonged Atrial Flutter.
Won Kwon KANG ; Dae Hoi KU ; Seung Hun SHIN ; Yeon Chae JEONG ; Eun Seok JEON ; Jong Hoon PARK
Korean Circulation Journal 1989;19(4):770-775
Myotonic dystrophy is a multisystemic disorder inherited as an autosomal dominant trait. The characteristic clinical features include the presence of myotonia, atrophy of the muscles of the face and the sternocleidomastoids and numerous nonmusclar manifestations such as cataracts, frontal baldness, gonadal dysfunctions and cardiac abnormalities. We experienced one case of myotonic dystrophy with prolonged atrial flutter in 30-year-old male who was admitted because of palpitation. We present this case with reviewing literatures.
Adult
;
Alopecia
;
Atrial Flutter*
;
Atrophy
;
Cataract
;
Gonads
;
Humans
;
Male
;
Muscles
;
Myotonia
;
Myotonic Dystrophy*