1.Cystic lymphangioma of the colon: case report.
Dae Yong HWANG ; Won Young HWANG ; Jin Cheon KIM ; Moon Gyu LEE ; Hae Ryun KIM ; Gyeong Yeob GONG ; Yong LEE
Journal of the Korean Society of Coloproctology 1992;8(3):311-317
No abstract available.
Colon*
;
Lymphangioma, Cystic*
2.The Differential Assessment of Human Cytomegalovirus Infectivity by in Situ Polymerase Chain Reaction.
Ki Chul SHIN ; Dae Joong KIM ; Jin Hee KIM ; Chung Gyu PARK ; Eung Soo HWANG ; Chang Yong CHA
Journal of the Korean Society for Microbiology 1999;34(4):363-372
No abstract available.
Cytomegalovirus*
;
Humans*
;
Polymerase Chain Reaction*
3.The new lymph nodes grouping of rectum in the rectal cancer.
Jin Cheon KIM ; Moon Gyu LEE ; In Chul LEE ; Dae Yong HWANG ; Byung Sik KIM ; Kun Choon PARK
Journal of the Korean Society of Coloproctology 1992;8(2):97-103
No abstract available.
Lymph Nodes*
;
Rectal Neoplasms*
;
Rectum*
4.A Case of Eosinophilia as a Manifestation of Paraneoplastic Syndrome in Non-Small-Cell Lung Cancer.
Hee Jung KIM ; Dae Joon JEONG ; Hui Young LEE ; In Gyu HWANG ; Seo Young SONG
Korean Journal of Medicine 2011;80(1):113-117
Eosinophilia is most frequently associated with asthma, allergic conditions, and parasitic infestation. Eosinophilia can also be associated with many forms of cancer. However, eosinophilia is infrequently associated with solid tumors. We experienced a 73-year-old-woman with eosinophilia as a manifestation of paraneoplastic syndrome that was combined with non-small-cell lung cancer (NSCLC). Initially, she was diagnosed with idiopathic hypereosinophilic syndrome, but was diagnosed with NSCLC 1 month later. Here, we report this case with a brief review of the literature.
Asthma
;
Carcinoma, Non-Small-Cell Lung
;
Eosinophilia
;
Hypereosinophilic Syndrome
;
Lung
;
Lung Neoplasms
;
Paraneoplastic Syndromes
5.A case of angioimmunoblastic lymphadenopathy presenting as polyarthritis.
Gwan Gyu SONG ; Seon Ho HWANG ; Ji Hoon KIM ; In Hong LEE ; Sung Soo JUNG ; Sang Cheol BAE ; Dae Hyun YOO ; Young Hae KO ; In Soon KIM ; Seong Yoon KIM
Korean Journal of Medicine 1993;45(3):383-387
No abstract available.
Arthritis*
;
Immunoblastic Lymphadenopathy*
6.Arterial to end-tidal carbon dioxide pressure gradient increases with age in the steep Trendelenburg position with pneumoperitoneum.
Dae Kee CHOI ; In Gyu LEE ; Jai Hyun HWANG
Korean Journal of Anesthesiology 2012;63(3):209-215
BACKGROUND: Several factors affect the end-tidal carbon dioxide pressure (PETCO2) and increase the arterial to end-tidal carbon dioxide pressure gradient (Pa-ETCO2) during general anesthesia. We evaluated the relationship between age and Pa-ETCO2 during pneumoperitoneum in the steep Trendelenburg position in patients undergoing robot-assisted laparoscopic prostatectomy (RALP). METHODS: Ninety-two consecutive patients undergoing RALP were divided by age into a middle-aged (45-65 years) and an elderly (> 65 years) group. Anesthesia was standardized. Heart rate, mean arterial pressure, peak inspiratory pressure, lung compliance, minute ventilation, PaO2, PETCO2, PaCO2, and Pa-ETCO2 were measured 10 min after intubation in the supine position without pneumoperitoneum (T0); and 10 (T1), 60 (T2), and 120 (T3) min after pneumoperitoneum in the Trendelenburg position. RESULTS: Although PETCO2 did not change significantly during surgery, PaCO2 and Pa-ETCO2 increased gradually with time during pneumoperitoneum in the Trendelenburg position, and both parameters showed greater increases in the elderly than in the middle-aged group. Simple linear regression analyses revealed significant correlations between age and Pa-ETCO2 at T0 (P = 0.018), T1 (P = 0.006), T2 (P < 0.001), and T3 (P = 0.001). Linear mixed model analysis showed that Pa-ETCO2 was associated statistically significantly with age and duration of pneumoperitoneum in the Trendelenburg position, but age and duration of pneumoperitoneum in the Trendelenburg position were not associated (P = 0.090). CONCLUSIONS: The magnitude of Pa-ETCO2 during pneumoperitoneum in the steep Trendelenburg position increased with age, which could be attributed to age-related respiratory physiological changes.
Aged
;
Anesthesia
;
Anesthesia, General
;
Arterial Pressure
;
Carbon
;
Carbon Dioxide
;
Head-Down Tilt
;
Heart Rate
;
Humans
;
Intubation
;
Linear Models
;
Lung Compliance
;
Pneumoperitoneum
;
Prostatectomy
;
Supine Position
;
Ventilation
7.Mapping of Human Cytomegalovirus IE1 Responsive Elements in the c-jun Promoter.
Dae Joong KIM ; Jin Hee KIM ; Sung Bae CHOI ; Tae Hee HAN ; Chung Gyu PARK ; Eung Soo HWANG ; Chang Yong CHA
Journal of the Korean Society of Virology 1998;28(3):267-274
Human cytomegalovirus (HCMV) has the ability to activate the espremission of many viral and cellular genes. Among various viral proteins, the immediate early proteins (IE1-72kDa, IE2-86kDa) have been known to be potent transactivators. The product of c-jun photo-oncogene is important in cell activation and differentiation. Here, we tried to find out if the IE could activate the c-jun promoter and also tried to identify the responsible sequence elements in the c-jun activation by IE1-72kDa. We found HCMV IE expression transactivated the c-jun promoter in human embryonal lung fibroblasts (HEL). The activation fold by IE1-72kDa, IE2-86kDa and IE2-55kBa was 23, 35, and 5, respectively. When the expression of each IE was combined, it showed synergism. Expression of (IE1-72kDa + IE2-86kBa) and (IE1-72kDa + IE2-86kDa + IE2-55kDa) resulted in 131 and 162 fold increase, respectively. The c-jun promoter region between -117 and -59 contains binding sites for the transcription factors Spl, CAAT, AP-1 like (ATF/CREB), and MEF2. Transient expression assays were performed using various reporter plasmids containing the c-jun promoter-regulatory region linked to the luciferase gene and a plasmic expressing HCMV IE1 gene. Deletional and point mutational analysis showed that the sequence between -225 to -160 and the CTF binding site were involved in the up-regulation of c-jun promoter.
Binding Sites
;
Cytomegalovirus*
;
Fibroblasts
;
Humans*
;
Immediate-Early Proteins
;
Luciferases
;
Lung
;
Plasmids
;
Promoter Regions, Genetic
;
Trans-Activators
;
Transcription Factor AP-1
;
Transcription Factors
;
Up-Regulation
;
Viral Proteins
8.Little role of anti-gB antibodies in neutralizing activity of patient's sera with human cytomegalovirus (HCMV) infection.
Jae Won PARK ; Dae Joong KIM ; Jinhee KIM ; Chung Gyu PARK ; Eung Soo HWANG ; Chang Yong CHA
Journal of Korean Medical Science 2000;15(2):133-138
Human cytomegalovirus (HCMV) gB is known to play important roles in cell surface attachment, virion penetration, spread of infection from cell to cell, and provocation of neutralizing antibody. This study was performed to determine the role of anti-HCMV gB antibody in overall neutralizing response in patients with HCMV infection and healthy control with past infection. HCMV gB was stably expressed in 293 cells. With the stable cell line expressing gB as a specific immunosorbent, anti-gB antibody was removed from the current and past HCMV-infected sera and the remaining neutralizing activity was measured by plaque assay. It was shown that 19-50% of the total virus-neutralizing activity of sera with past HCMV infections was derived from anti-gB antibody, but anti-gB antibody had little effect on the total serum virus-neutralizing activity in patients currently infected with HCMV. This result suggests that neutralizing antibody to HCMV gB may reflect disease status.
Adult
;
Antibodies, Monoclonal
;
Antibodies, Viral/immunology*
;
Antibodies, Viral/blood
;
Antigens, Viral/immunology
;
Antigens, Viral/genetics
;
Cells, Cultured
;
Cytomegalovirus/immunology*
;
Cytomegalovirus Infections/prevention & control
;
Cytomegalovirus Infections/immunology*
;
Female
;
Fetus/cytology
;
Fibroblasts/cytology
;
Gene Expression Regulation, Viral/immunology
;
Human
;
Immunosorbents
;
Lung/cytology
;
Male
;
Middle Age
;
Neutralization Tests
;
Recombinant Proteins/genetics
;
Viral Envelope Proteins/immunology*
;
Viral Vaccines
9.A Case of Thyroid Abscess Caused by Salmonella Group D in a Patient with Systemic Lupus Erythematosus.
Byung Yoen HWANG ; Yong Hyoen KIM ; Young Hee RHO ; Young Ho LEE ; Jong Dae JI ; Gwan Gyu SONG
The Journal of the Korean Rheumatism Association 2003;10(4):442-445
Infectious disease took the leading cause of death in patients with systemic lupus erythematosus (SLE). Especially Salmonella infection occurs more common in SLE patients. We report a case of thyroid abscess caused by Salmonella Group D in a patient with SLE. A patient, 29-year-old female, with SLE was admitted with a painful swelling of the left neck and diarrhea. The painful swelling of neck was revealed as an abscess of the thyroid and Salmonella Group D was isolated from the aspirated material of the thyroid abscess. The patient recovered after surgical drainage and administration of intravenous 3rd cephalosporin.
Abscess*
;
Adult
;
Cause of Death
;
Communicable Diseases
;
Diarrhea
;
Drainage
;
Female
;
Humans
;
Lupus Erythematosus, Systemic*
;
Neck
;
Salmonella Infections
;
Salmonella*
;
Thyroid Gland*
10.Eukaryotic Expression of Human Cytomegalovirus ( HCMV ) Glycoprotein H ( gH ).
Chung Gyu PARK ; Yoon Hoh KOOK ; Chang Yong CHA ; Eung Soo HWANG ; Sung Bae CHOI ; Jin Hee LEE ; Dae Joong KIM
Journal of the Korean Society for Microbiology 1999;34(4):321-326
Human cytomegalovirus (HCMV) glycoprotein H (gH) is one of target molecules in the human immune response to HCMV infection. This study was performed to rneasure the immune responses to HCMV gH in human sera by the expression of HCMV gH in eukaryotic cells. Amplified DNA from the gene encoding gH of HCMV by polymerase chain reaction was cloned into pcDNA3 to construct eukaryotic expression vector. Immunofluorescent staining revealed that the expressed gH in mammalian cells was reactive with the specific monoclonal antibody. Antibody titer in patient's sera with HCMV infection was measured with HCMV-infected fibroblasts and HCMV gH expressed in mammalian cells. Anti-HCMV gH antibody titer was higher in patient group than in healthy control group. There was no correlation between the antibody titer to the whole HCMV and neutralizing antibody titer, and between the antibody titer to whole HCMV and whole gH. Conclusively it is highly recommendable to use the defined antigen such as HCMV gH for the detection of antibody in HCMV-infected persons in the aspect of immunological properties.
Antibodies, Neutralizing
;
Clone Cells
;
Cytomegalovirus*
;
DNA
;
Eukaryotic Cells
;
Fibroblasts
;
Glycoproteins*
;
Humans*
;
Polymerase Chain Reaction