No abstract available.

No abstract available.
Myositis Ossificans* ; Myositis*

PURPOSE: We analyzed the clinical outcome of osteosarcoma developed in distal radius and the effect of delayed treatment on prognosis. MATERIALS AND METHODS: Twelve patients with distal radius osteosarcoma were analysed. We categorized patients into two groups of standard treatment or non-standard treatment. The patients of standard treatment group are all stage IIB and non-standard treatment group includes five stage IIB and one stage III. RESULTS: Five-year overall survival and disease-free survival rates of standard treatment group were 100% and 83%. Five-year overall survival rate of non-standard treatment group was 44%. Between two group, there are differences in age, tumor size, surgery type, symptom duration. CONCLUSION: Distal radius osteosarcoma have good prognosis than other extremity osteosarcoma. Survival rate of non-standard treatment group were lower than standard treatment group. Although the prognosis of non standard treatment group is poorer, the duration till death was longer than that of other sites with similar condition. Further multi-institutional study should be needed.
Disease-Free Survival ; Extremities ; Humans ; Osteosarcoma ; Prognosis ; Radius ; Survival Rate

BACKGROUND: Spinal anesthesia potentiates sedative drug effects. We speculated that an acute decrease in tonic afferent input by spinal anesthesia would decrease the level of consciousness and thereby increase susceptibility to sedative drugs. The experiments were approached with the assumption that the amount of sedative would reduce in the following order: first, the group without spinal anesthesia, second, the group with unilateral spinal anesthesia, and third, the group with conventional spinal anesthesia. METHODS: Patients in group 1 (n = 20) were given midazolam without spinal anesthesia and patients in group 2 (n = 20) received unilateral spinal anesthesia. Those patients who after 20 minutes had a sensory level of T9-11 and a motor block of 3 in dependent side, no sensory block, and a motor block of 0 in the non-dependent side were included. In group 3 (n = 20), patients received conventional spinal anesthesia, and those patients who after 20 minutes had a sensory level of T9-11 and a motor block of 3 were included. The amount of midazolam administered at 33microgram/kg/min to a Bispectral Index score (BIS) of 80 was measured. RESULTS: The dose of midazolam administered to a BIS of 80 was significantly lower in group 3 than in group 1 or group 2. CONCLUSIONS: The sensitivity of sedatives was in the following order: the group with conventional spinal anesthesia, the group with unilateral spinal anesthesia, and the group not administered spinal anesthesia.
Anesthesia, Spinal* ; Consciousness ; Humans ; Hypnotics and Sedatives ; Midazolam*

No abstract available.
Drug Therapy* ; Extremities* ; Osteosarcoma*

No abstract available.
Calcinosis*

No abstract available.
Histiocytoma, Malignant Fibrous*

No abstract available.
Femur* ; Osteosarcoma*

No abstract available.
Giant Cell Tumors* ; Giant Cells*

Ankylosing spondylitis is an inflammatory disorder of unknown etiology that primarily affect, the spine, the axial skeleton, and the large proximal joints of the body with striking tendancy toward fibrosis with secondary ossification and ankylosis of involved joints. This study was carried out to analyse clinical manifestation, evaluate disease activity indicator and set up diagnostic work-up. 38 cases of ankylosing spondylitis were studied at Department of Orthopedic Surgery, Seoul National University from Oct. 1987 to Mar. 1989. Following results were obtained. l. Average age was 28.5 years and all patients were male. 2. Low back pain was the most frequent symptom(63%) and back stiffness was next(13%). 3. S-I joint change on x-ray was the most frequently found abnormalities(100%) and HLA B27 (+) was next(97%). 4. SI/S ratio was inversely correlated with duration of symptom and seems to be significant durng the early phase of disease. 5. As a disease activity indicator, CRP was more reliable than ESR during follow up.
Ankylosis ; Clinical Study ; Fibrosis ; Follow-Up Studies ; Humans ; Joints ; Low Back Pain ; Male ; Orthopedics ; Seoul ; Skeleton ; Spine ; Spondylitis, Ankylosing ; Strikes, Employee