1.Abducens Nerve Palsy after Lumbar Spinal Fusion Surgery with Inadvertent Dural Tearing.
Dae Chul CHO ; Eul Soo JUNG ; Yong Chul CHI
Journal of Korean Neurosurgical Society 2009;46(6):581-583
Abducens nerve palsy associated with spinal surgery is extremely rare. We report an extremely rare case of abducens nerve palsy after lumbar spinal fusion surgery with inadvertent dural tearing, which resolved spontaneously and completely. A 61-year-old previous healthy man presented with chronic lower back pain of 6 weeks duration and 2 weeks history of bilateral leg pain. He was diagnosed as having isthmic spondylolisthesis at L4-5 and L5-S1, and posterior lumbar interbody fusion was conducted on L4-5 and L5-S1. During the operation, inadvertent dural tearing occurred, which was repaired with a watertight dural closure. The patient recovered uneventfully from general anesthesia and his visual analogue pain scores decreased from 9 pre-op to 3 immediately after his operation. However, on day 2 he developed headache and nausea, which were severe when he was upright, but alleviated when supine. This led us to consider the possibility of cerebrospinal fluid leakage, and thus, he was restricted to bed. After an interval of bed rest, the severe headache disappeared, but four days after surgery he experienced diplopia during right gaze, which was caused by right-side palsy of the abducens nerve. Under conservative treatment, the diplopia gradually disappeared and was completely resolved at 5 weeks post-op.
Abducens Nerve
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Abducens Nerve Diseases
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Anesthesia, General
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Bed Rest
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Diplopia
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Headache
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Humans
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Leg
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Low Back Pain
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Middle Aged
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Nausea
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Paralysis
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Spinal Fusion
;
Spondylolisthesis
2.Dopamine Transporter Gene and Dopamine D2, D3, D4 Receptor Gene Polymorphisms in Attention Deficit Hyperactivity Disorder.
Pil Sang PARK ; Dae Kwang KIM ; Chul Ho JUNG
Journal of the Korean Academy of Child and Adolescent Psychiatry 2008;19(1):19-27
OBJECTIVES: The aim of this study was to examine the association of attention-deficit hyperactivity disorder (ADHD) in Korean populations with functional polymorphisms of six genes dopamine receptors (Ser311/Cys311 polymorphism, Taq1 A polymorphism, and Taq1 B polymorphism in DRD2, BalI polymorphism in DRD3, and promoter -521 C/T polymorphism and exon III 48 bp repeat polymorphism in DRD4) and one gene in dopamine transporter (DAT1). METHODS: Participants were 58 children with ADHD and 110 control children. The genotypes were determined by PCR. RESULTS: There was a statistically significant difference in genotype frequency of -521 C/T polymorphism within the promoter region of the DRD4 between two groups. Furthermore, in the male group, both genotype and allele frequencies showed statistically significant differences. CONCLUSION: Findings of the study indicate that -521 C/T polymorphism in promoter region of DRD4 appears to be a possible candidate gene for ADHD in Korean population.
Attention Deficit Disorder with Hyperactivity
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Child
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Dopamine
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Dopamine Plasma Membrane Transport Proteins
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Exons
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Gene Frequency
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Genotype
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Humans
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Male
;
Promoter Regions, Genetic
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Receptors, Dopamine
3.Computer-assisted interpretative reporting system of serum CK and LD isoenzyme tests.
Dae Chul KIM ; Bo Chan JUNG ; Kil Ho CHO ; Kyung Dong KIM ; Chung Sook KIM
Korean Journal of Clinical Pathology 1991;11(2):349-362
No abstract available.
4.Comparison of the results of multistix®-SG and comber-9-Test®RL urine dipstick assay.
Dae Chul KIM ; Kyung Dong KIM ; Bo Chan JUNG ; Chung Sook KIM ; Kil Ho CHO
Yeungnam University Journal of Medicine 1991;8(1):42-52
Two types of urine dipstick assays, Multistix-SG and Comber-9-Test RL, were compared for compatibility, accuracy, specificity and predictive values of a positive and negative test in 501 patients' urine and artificially prepared specimen. We found that the results of semiquantitative tests of Multistix-SG and Comber-9-Test RL performed were statistically similar in patients' specimen. The urinary leukocyte esterase tests of Comber-9-Test RL assays compared with urine sediment microscopy in regard to compatibility, sensitivity, specificity, and predictive values of a positive and negative test 83.7%, 48.1%, 90.3%, 47.4% and 90.1%, respectively. The urinary nitrite tests of Comber-9-Test RL assays compared with urine culture tests, in regard to compatibility, sensitivity, specificity, and predictive values of a positive and negative test were 90.3%, 19.4%, 84.7%, 53.8% and 94.1, respectively. For the urinary protein, the sulfosalicylic acid method was the most sensitive test for any kinds of protein, and Multistix-SG appeared more sensitive than Comber-9-Test RL for the albuminuria. For the urinary bilirubin and glucose, two dipstick assays were similar in their diagnostic efficiency. Finally in the urinary occult blood tests, Comber-9-Test RL assays was more sensitive than Multistix-SG.
Albuminuria
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Bilirubin
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Glucose
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Leukocytes
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Methods
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Microscopy
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Occult Blood
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Sensitivity and Specificity
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Urinalysis
5.Spinal Cord Infarction following Spine Surgery in the Patient with Vertebral Bursting Fracture : A case report.
Sang Jin PARK ; Hyun Chul JUNG ; Dae Lim JEE
Korean Journal of Anesthesiology 2007;52(4):471-474
Spinal cord infarction as a complication of spine surgery occurs rarely. Herein, a case of spinal cord infarction, which developed in a 69 year old woman following posterior decompression and internal fixation for a T11 bursting fracture, is descirbed. The anesthetic induction and intraoperative course were uneventful, except at the end of the procedure, where her blood pressure suddenly dropped from 130/90 to 90/60 mmHg. The patient was aggressively treated with a transfusion and vasopressor, the blood pressure then returned to its usual value within 10 minutes. However, during a physical examination in the recovery room, the patient was found to have flaccid lower limbs, with impaired sensory function below the T8 level. Her cord diameter had increased, and a high signal lesion was observed within the thoracic spinal cord, from T9 to T12 level on T2-weighted MR images, which was diagnosing as a spinal cord infarction, was and showed no improvement despite the immediate and aggressive treatment.
Aged
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Blood Pressure
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Decompression
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Female
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Humans
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Infarction*
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Lower Extremity
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Physical Examination
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Recovery Room
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Sensation
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Spinal Cord*
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Spine*
6.3 cases of tsutsugamushi disease with meningitis in children.
Byung Keun LEE ; Tae Hee PARK ; Soo Chul CHO ; Dae Yul LEE ; Jung Soo KIM
Korean Journal of Infectious Diseases 1993;25(2):183-187
No abstract available.
Child*
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Humans
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Meningitis*
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Scrub Typhus*
7.Two cases of hybrid leukemia.
Sung Dong CHOI ; Dae Chul JUNG ; Woo Gun CHOI ; Hack Ki KIM ; Kyong Su LEE
Journal of the Korean Pediatric Society 1991;34(1):130-136
No abstract available.
Leukemia*
8.Two Case of Systemic Candidiasis in Premature Infants.
Dae Kyun KIM ; Woo Chul SUH ; Eun Gyeoung JUNG ; Eun Seok YANG ; Sang Kee PARK
Journal of the Korean Pediatric Society 1995;38(11):1558-1564
No abstract available.
Candidiasis*
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Humans
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Infant, Newborn
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Infant, Premature*
9.A Case of Follicular Adenoma Occurring in Congenital Goiter due to Dyshormogensis.
Jung Chul KIM ; Hyun Seup SIM ; Myoung Jea KANG ; Dae Yeol LEE
Journal of Korean Society of Pediatric Endocrinology 2002;7(1):112-115
Follicular adenoma is a benign encapsulated tumor with evidence of follicular cell differentiation. It is the most common thyroid neoplasm, usually solitary and has a well-defined fibrous capsule. We experienced a case of follicular adenoma occurring in congenital goiter and reported with the brief review of related literature
Adenoma*
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Cell Differentiation
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Goiter*
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Thyroid Neoplasms
10.Characteristics of Serum Insulin-like Growth Factor ( IGF ) and IGF-Bindign Protein-3 during Pregnancy.
Dae Yeol LEE ; Jung Soo KIM ; Hong Ro LEE ; Cheol Hee RHEE ; Soo Chul CHO
Journal of Korean Society of Endocrinology 1997;12(3):376-385
BACKGROUND: Pregnancy in human and rodents is associated with dramatic matemal metabolic changes. Insulin-like growth factors (IGFs) are mitogenic peptides that are essential for fetal and maternal tissue growth during pregnancy. They circulate complexed primarily with a serum IGF-binding protein (IGFBP-3) which regulates the availability of the IGFs to their specific target tissues. METHODS: To examine the changes of IGFs and IGFB-3 during pregnancy, we measured serum total IGF-I, free IGF-I, IGF-II and IGFBP-3 by using specific radioimmunoassay, immunoradio-metric assay, western ligand blot and western immunoblot. Blood samples were obtained from 88 pregnant women between 6-40 weeks gestation. RESULTS: While serum IGF-I levels increased up to 50% in late pregnancy, serum IGF-II levels remained unchanged. However, serum free IGF-I levels were significantly higher during pregnancy than in nonpregnancy. Western ligand blot analysis revealed that IGFBP-3 in pregnancy serum was significantly decreased at 6 weeks of gestation, continued decreased level until term, and returned to a nonpregnant level by postpartum 10 day. Serum IGFBP-3 profiles in Western immunoblot analysis revealed that 30 kDa fragments of IGFBP-3 were detectable in pregnancy serum but not in nonpregnancy serum. In contrast, serum IGFBP-3 levels using radioimmunoassay was significantly increased in late pregnancy. CONCLUSIONS: 1) serum IGF-I was significantly elevated in late pregnancy 2) serum IGF-II was not significantly changed 3) free IGF-I significantly elevated throughout gestation 4) intact IGFBP-3 was markedly reduced after 6 weeks of gestation.
Blotting, Western
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Female
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Humans
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Insulin-Like Growth Factor Binding Protein 3
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Insulin-Like Growth Factor I
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Insulin-Like Growth Factor II
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Peptides
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Postpartum Period
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Pregnancy*
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Pregnant Women
;
Radioimmunoassay
;
Rodentia
;
Somatomedins