1.A Case of Tethered Cord Syndrome Manifested with a Neurotrophic Ulcer.
Dae Young KIM ; Seung Chul LEE ; Young Ho WON ; Inn Ki CHUN
Annals of Dermatology 1995;7(4):346-349
We report herein a case of tethered cord syndrome with recurrent ulcerations of the skin in a 17-year-old girl. The patient presented an asymptomatic punched-out deep ulcer on the right buttock and right heel. The lesions were noticed as bullae on the sites, which developed into ulceration. At birth, a reddish nodule was noted on the lower back, which was excised when she was 3 years old at a private clinic. Neurological examination revealed hypoesthesia below the LS dermatome. We suspected a simple neurotrophic ulcer which was treated with zinc oxide dressing and oral antibiotics. 1 month later, the ulcers had healed, but tense bullae had developed on the same right buttock. Spina bifida with intraspinal lipoma was revealed by plain X-ray film and magnetic resonance imgaing. Tethered cord syndrome was diagnosed, and treated with a surgical excision of the lipoma, and repair of the dura. This is a vary rare etiology of a neurotrophic ulcer due to a central nervous system disease, and is the first reported case in the Korean dermatologic literature.
Adolescent
;
Anti-Bacterial Agents
;
Bandages
;
Buttocks
;
Central Nervous System
;
Female
;
Heel
;
Humans
;
Hypesthesia
;
Lipoma
;
Neural Tube Defects*
;
Neurologic Examination
;
Parturition
;
Skin
;
Spinal Dysraphism
;
Transcutaneous Electric Nerve Stimulation
;
Ulcer*
;
X-Ray Film
;
Zinc Oxide
2.Clinical esxperiences of Carotid Endarterectomy for Carotid Stenosis.
In Suk CHOI ; Choo Chul PARK ; Gyung Chun JUNG ; Dae Il JANG
The Korean Journal of Thoracic and Cardiovascular Surgery 1999;32(12):1087-1092
BACKGROUND: The purpose of carotid endarterectomy is to prevent stroke regardless of past neurologic events. Major concern in the carotid endarterectomy is the inadequate blood flow of ipsilateral hemisphere during clamping of the carotid artery. It is well known that internal carotid artery back pressure means collateral cerebral blood flow. Our study is intended to determine the guideline of shunt placement according to the carotid back pressure and electroencephalographic finding. MATERIAL AND METHOD: The study population comprised of 16 consecutive patients who underwent carotid endarterectomy for carotid stenosis in our institution between from February 1996 to March 1999. There were 14 men and 2 women between the ages of 56 and 78 years(mean age 66.25+/-6.53 years). The carotid stenosis in the operative site was ranged from 61% to 95%(mean 73.8+/-12.33%) and the mean carotid stenosis of the contralateral side was 60.99+/-25.03%. During the operation, electroencephalographic monitoring was taken in all cases. The internal carotid artery back pressure was measured to estimate the collateral cerebral blood flow, and in all patients with back pressure below 40 mmHg(11 patients) and patients with complete occulusion of contralateral carotid artery(2 patients), an internal shunt was installed. RESULT: One postoperative death occurred in a patient with large evolving cerebral infarction and severe ipsilateral carotid stenosis, who underwent emergent carotid endarterectomy. The cause of death was hemorrhagic infarction in the corresponding cerebral territory. We observed that immediate operation after a major stroke negatively influenced the postoperative outcome. No intraoperative ischemic neurologic complication developed. During the follow-up upto now(mean follow-up 21.5+/-11.85 months), there has been no early or late recurrence of stroke except one patient ,in whom cerebral infarction developed in the contralateral side on the first postoperative day. CONCLUSION: At least 4-6 weeks stabilization after a stroke is recommended for surgical management. The carotid endarterectomy is an effective surgical intervention for prevention of anticipated stroke and can be performed safely if an internal shunt is used in patients whose internal carotid arterial back pressure is below 40 mmHg.
Carotid Arteries
;
Carotid Artery, Internal
;
Carotid Stenosis*
;
Cause of Death
;
Cerebral Infarction
;
Constriction
;
Endarterectomy
;
Endarterectomy, Carotid*
;
Female
;
Follow-Up Studies
;
Humans
;
Infarction
;
Male
;
Recurrence
;
Stroke
3.A Case of nevoid Basal Cell Carcinoma Syndrome with Basal Cell Carcinoma developing in a Palmar Pit.
Dae Young CHO ; Seung Chul LEE ; Young Ho WON ; Inn Ki CHUN
Korean Journal of Dermatology 1996;34(4):684-688
Nevoid basal cell carcinoma syndrome is a genetically determined disorder characterized by multiple basal cell carcinoma, palmoplantar pits and defects in other organs or tissues. Basal cell carcinoma may arise any sit of body. But infrequently typical basal cell carcinomas arise from the depressed epidermis which forms the base of the pits on the hands and feet. The patient was a 12 years old girl who developed multiple black-colored papules on the face and a dark reddish to black-colored pit over the palm and skin-colored depressed circumscribed pits on the plantar surface of feet. she also had an odontogenic cyst in the right maxilla, epidermal cyst on the trunk and mutiple intradermal nevi on the face. But the family history was not present. The histopathologic findings of the depressed pit of the palm showed a crater on the stratum corneum, and a well marginated tumor nest of basal cell carcinoma showing keratotic feature on the center of the lesion and reticulated feature on the periphery.
Basal Cell Nevus Syndrome*
;
Carcinoma, Basal Cell*
;
Child
;
Epidermal Cyst
;
Epidermis
;
Female
;
Foot
;
Hand
;
Humans
;
Maxilla
;
Nevus, Intradermal
;
Odontogenic Cysts
4.Use of Femoral Head Allograft for Severe Bone Defect in Primary Total Knee Arthroplasty and Revision Total Knee Arthroplasty.
Churl Hong CHUN ; Dae Ho HA ; Dong Chul KIM ; Dae Sic AHN
Journal of the Korean Knee Society 2002;14(1):9-15
PURPOSE: To investigate the clinical and radiological results after primary or revision total knee arthroplasty using fresh frozen femoral head strut allograft for severe bone defect. SUBJECTS AND METHODS: Seventeen patients (18 cases) with severe bone defect were taken primary or revision TKA from 1997 to 2001 using fresh frozen femoral head allograft. 12 cases of revision TKA and 6 of primary TKA were conducted. The average age was 66 years old(55~74) and the follow up period was 29 months(12~63 months). Bone defects were found at proximal tibia in 10 cases, distal femur in 2 and both sites in 6 cases. PCL substituting TKA with extension rod were 15, and PCL retaining TKA were 3. The clinical result was assessed with the knee score of Hospital for Special Surgery(HSS) and for assessment of allograft, simple X-ray film was employed. RESULTS: Average range of motion was increased from 71 degrees to 103 degrees and HSS score was increased from 46(18 ~68) to 83(68 ~91). With 17 of 18 femoral head strut allograft, union was seen and no clinical collapse was present. In one, partial allograft absorption was occured. The preoperative alignment was an average of 7 degrees varus(range 5 degrees~15 degrees) and postoperative alignment was averaged 6.1 degrees valgus(range 3 degrees ~7 degrees). No radiolucent lines were 2 mm or more in width, and there was no case of infection or fracture of allograft. CONCLUSIONS: Femoral head strut allograft was a satisfactory method of managing severe bone defect in primary or revision TKA.
Absorption
;
Allografts*
;
Arthroplasty*
;
Femur
;
Follow-Up Studies
;
Head*
;
Humans
;
Knee*
;
Range of Motion, Articular
;
Tibia
;
X-Ray Film
5.Clinical Analysis of Spinal Cord Hemangioblastoma.
Dae Kyu LEE ; Woo Jin CHOE ; Dong Yoon KIM ; Chul Hee LEE ; Chun Kee CHUNG ; Hyun Jib KIM
Journal of Korean Neurosurgical Society 2001;30(11):1291-1299
OBJECTIVES: The authors present a retrospective analysis of 14 patients treated for spinal cord hemangioblastoma (SCH) between Dec. 1986 and Mar. 2000. This study was conducted to evaluate and compare the difference of the functional outcomes associated with the extent of surgical removal of SCH. METHODS: Eleven patients were male and three patients were female. Their mean age was 37.2 years that ranged from 19 to 62 years. Preoperative magnetic resonance(MR) imaging of the spine was performed in all cases, and preoperative angiography in eleven cases. They were followed from 15 months to 161 months(median follow-up period, 47 months), and we investigated the change of neurological symptoms and functional outcomes with radiological features, especially on MR imaging. RESULTS: Six patients were accompanied by von Hippel-Lindau disease, and three of them had multiple CNS tumors. Thirteen patients had intramedullary tumor, and the remaining one had extradural. Syringomyelia around the tumor was observed in ten cases. All patients underwent surgical removal, and gross total removal(GTR) was achieved in ten cases. Preoperative embolization was performed in four cases. In four patients who were treated with preoperative embolization, intraoperative loss of blood was minimal and GTR was possible. One patient developed a transient swallowing difficulty postoperatively without permanent postoperative neurological deficits. In three of four patients in whom GTR was not possible, their functional outcomes were worsened postoperatively. The functional status at discharge was improved in seven patients, stationary in four patients, and worse in three. At the last follow-up(15-161 months), one of four patients who had been stationary at discharge showed improvement but, the rest did not show any change. All patients who showed neurological improvement were patients with GTR, and the patients with GTR had significant better outcome than those without GTR(p=0.015). CONCLUSION: Surgical treatment, and especially, GTR is considered as treatment of choice for spinal cord hemangioblastoma. Preoperative embolization may prevent intraoperative bleeding and improve surgical outcome.
Angiography
;
Deglutition
;
Female
;
Follow-Up Studies
;
Hemangioblastoma*
;
Hemorrhage
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Retrospective Studies
;
Spinal Cord*
;
Spine
;
Syringomyelia
;
von Hippel-Lindau Disease
6.A Case of Intestinal Leiomyosarcoma with Metastasis to the Liver.
Moo Jun BAEK ; Dae Joong KIM ; Moon Soo LEE ; Hyung Chul KIM ; Chang Ho KIM
Korean Journal of Hepato-Biliary-Pancreatic Surgery 1998;2(1):133-137
Leiomyosarcoma of the intestine is an uncommon malignant tumor of the small and large bowels. It may metastasize mostly to the peritoneum, omentum and liver. We describe a case of a liver metastasis from ileal leiomyosarcoma which was treated by right hepatic lobectomy. Ultrasonography revealed multiple cysts in both lobes of liver and pelvic mass. Computerized tomography of the abdomen revealed that lobulated, marginated, low density mass was noted in ileal loop, and multiple, well-defined, low density masses were identified in both lobes of the liver. The patient underwent exploratory laparotomy and removal of the ileal leiomyosarcoma. One month later, the patient underwent a right hepatic lobectomy and removal of a cystic mass on the liver dome of the left lobe. The patient recovered and was discharged by postoperative day 24.
Abdomen
;
Humans
;
Intestines
;
Laparotomy
;
Leiomyosarcoma*
;
Liver*
;
Neoplasm Metastasis*
;
Omentum
;
Peritoneum
;
Ultrasonography
7.Postoperative Monotherapy with Piperacillin-Tazobactam versus Multidrug Therapy with Cefotaxime and Metronidazole for Perforated Appendicitis in Children: A Case-Control Study.
Sung Jin CHUN ; Dae Yeon KIM ; Seong Chul KIM ; Jung Man NAMGOONG
Journal of the Korean Association of Pediatric Surgeons 2015;21(2):28-31
PURPOSE: Recent data suggest that monotherapy with a broad-spectrum antibiotic may be as efficacious as, and potentially less costly than, standard multi-drug therapy. We compared mono-therapy with intravenous piperacillin-tazobactam (PT) with multi-drug therapy with cefotaxime and metronidazole (CM) in aspect of postoperative complications and hospital stay. METHODS: We reviewed the hospital records and medical costs of the pediatric patients who were managed for perforated appendicitis between April 2013 and May 2014 retrospectively. RESULTS: Forty-six patients with laparoscopic appendectomy for perforated appendicitis were included in our study. PT group was 20 and CM group was 26 patients. On admission, there were no significance in sex distribution, duration of symptoms, leukocyte count, and CRP levels. At postoperative third, fifth, and seventh day of each regimen, PT group have no statistical difference with CM group in leukocyte count, percentage of neutrophil, and CRP. There was no difference in abscess formation rate, wound infections, and hospital stay between two groups. There was only one patient who was readmitted with elevation of CRP and leukocyte count in CM group. CONCLUSION: Daily dosing with the mono-therapy of PT offers as efficient as multi-drug therapy of CM. To evaluate the efficacy of broad-spectrum antibiotics monotherapy in perforated appendicitis children, the cohort included more patients should be needed.
Abscess
;
Anti-Bacterial Agents
;
Appendectomy
;
Appendicitis*
;
Case-Control Studies*
;
Cefotaxime*
;
Child*
;
Cohort Studies
;
Hospital Records
;
Humans
;
Length of Stay
;
Leukocyte Count
;
Metronidazole*
;
Neutrophils
;
Postoperative Complications
;
Retrospective Studies
;
Sex Distribution
;
Wound Infection
8.Review of the Patch Test Results in patients with the Cosmetic Contact Dermatitis.
Hee Chul EUN ; Oh Sang KWON ; Koo Il SEO ; Chun Sik YOUN ; Won Seok HAN ; Dae Hun SUH
Korean Journal of Dermatology 1999;37(8):1009-1016
BACKGROUND: Contact dermatitis is frequently caused by cosmetics. Detection of causative allergens is important in prevention and treatment of cosmetic contact dermatitis. Patch test has been accepted as the only reliable diagnostic method to detect allergens. OBJECTIVE: The objectives of this study were to clarify evoluting trends of positive patch tests and to compare the positive frequencies of various allergens between different time sequences. MATERIALS AND METHODS: We reviewed patch test results of the 806 cosmetic contact dermatitis patients, who had visited our clinic from 1982 to 1997. We divided the patients into three groups as follows: I group:1982-1987, II group:1988-1992, III group:1993-1997 and compared the test results. The patch tests were performed with standard batteries, cosmetic-related allergens and the patients's own cosmetics. RESULTS: The results of the studies were summarized as follows; 1. Trends of increasing positivity in cosmetic-induced dermatitis was noted in a chronologic point of view. Among the patients, an increased proportion of males was notable. 2. In age distribution, a decreasing proportion of patients at the third & the fourth decades was observed. Contrary to this, the proportion of patients over the fifth decades was increased. 3. Among standard allergens, nickel sulphate showed the highest positive rate in all defined triple periods, whereas positive rates of neomycin sulphate & balsam of Peru were diminishing sequentially. Among fragrance allergens, cinnamic alcohol & cinnamic aldehyde revealed the highest positive rates. 4. In as is test, skin care products showed the highest positive rate, followed by toiletries and makeup products. Increasing positive rates of the toiletry products were observed in order of time. In fragrance products, positive rates reached their peak in the second period and declined in the third period. CONCLUSION: This study showed that perfume components were the most frequent allergens in cosmetics followed by preservative agents. Our study showed that comestic allergies in men seems to have increased.
Age Distribution
;
Allergens
;
Dermatitis
;
Dermatitis, Allergic Contact
;
Dermatitis, Contact*
;
Humans
;
Hypersensitivity
;
Male
;
Neomycin
;
Nickel
;
Patch Tests*
;
Perfume
;
Peru
;
Skin Tests
9.Familial Systemic Lupus Erythematosus Developed in Two Sisters.
Jong Hyuk PARK ; Dae Young CHO ; Seong Jin KIM ; Seung Chul LEE ; Young Ho WON ; Inn Ki CHUN
Korean Journal of Dermatology 1997;35(6):1220-1224
The pathogenesis of systemic lupus erythematosus (SLE) appears to be multifactorial, including both genetic and environmental influences. The genetic factor of SLE is well known to have an important role in the pathogenesis based on epidemiological analysis and studies of monozygotic twins. The disease occur. more commonly in first degree relatives and may affect multiple persons in single families. We report a family in which two sisters developed systernic lupus erythematosus. The clinical, laboratory and histopathological findings showed characteristic features of systemic lupus erythematosus. HLA testing revealed that the two sisters shared common HLA-DR15(2)and HLA-A2.
HLA-A2 Antigen
;
Humans
;
Lupus Erythematosus, Systemic*
;
Siblings*
;
Twins, Monozygotic
10.A Case of Pelvic Neurilemoma.
Hee Cheol YOON ; Chee Young CHUNG ; Sang Jun CHUN ; Kyung Min PARK ; Hee Su PARK ; Jon RHO ; Chul Sung KIM ; Dae Soo JANG
Korean Journal of Urology 2000;41(7):907-909
No abstract available.
Neurilemmoma*