OBJECTIVE:To provide reference for rational drug use and strengthen the management of adjuvant medication man-agement in the hospital. METHODS:1 080 and 860 discharged medical records of 12 Vitamins for injection were selected from our hospital during Jun.-Nov. 2014 (pre-special comment group,i.e. group A) and Jun.-Nov. 2015 (post-special comment group,i.e. group B),respectively. The application of 12 Vitamins for injection,hospitalization stay,drug cost and the incidence of ADR were compared before and after adjuvant medication special comment. RESULTS:After adjuvant medication special comments,the propor-tion of drug use of no indication,unsuitable solvent selection,irrational drug dosage,drug use of drug interaction and contraindica-tion,drug cost and the incidence of ADR in group B were all lower than in group A,with statistical significance(P<0.05). There was no statistical significance in hospitalization stay between 2 groups(P>0.05). CONCLUSIONS:Clinical pharmacists adopt adju-vant medication special comments to effectively standardize clinical application of 12 Vitamins for injection in our hospital.

Objective To study the difference of plantar pressure before and after needle-knife surgery on patients with calcaneodynia, so as to evaluate its efficacy and provide evidence to the clinical applica-tion of needle-knife therapy. Methods A total 70 patients with calcaneodynia were divided into two nee-dle-knife therapy groups ( treatment group, each n=35 ) . After local anesthesia, the needle-knife was inserted into quickly guided by the plantar fascia scale, perpendicular to the direction of metatarsal fasci-a, then cut and separated the ligaments and fascia attached to the bone spur three to five times. In treat-ment group 1, the needle-knives were inserted to half of the scale, and in the treatment group 2, the nee-dle-knives were inserted to quarter of the scale. 35 more patients were assigned to the control group who received blocking therapy. Peak pressure values of medial forefoot ( MFF) , lateral forefoot ( LFF) , mid-foot ( MF) , medial heel ( MHEEL) and lateral heel ( LHEEL) were measured before and after treatment using Footscan USB2 System manufactured in RSscan Co. Ltd. Results There was no difference of MFF pressure in the two treatment groups before and after need-knife therapy, but pressures of LFF, MF, MHEEL and LHEEL showed significant differences between after and before treatement ( P<0 . 05 ) . In control group, the pressures of MFF, MF and MHEEL had no significant differences between before and after treatment, while that of LFF and LHEEL showed differences(P <0. 05). Conclusion Needle-knife surgery can effectively attenuate the plantar stress changes of the patients with calcaneodynia, and be benefit for recovery the normal lines of force of patients’ feet.

The technology of three-dimensional(3D)printing emerged in the late 1970s and has since undergone considerable development to find numerous applications in mechanical engineering,industrial design,and biomedicine.In biomedical science,several studies have initially found that 3D printing technology can play an important role in the treatment of diseases in hepatopancreatobiliary surgery.For example,3D printing technology has been applied to create detailed anatomical models of disease organs for preoperative personalized surgical strategies,surgical simulation,intraoperative navigation,medical training,and patient education.Moreover,cancer models have been created using 3D printing technology for the research and selection of chemotherapy drugs.With the aim to clarify the development and application of 3D printing technology in hepatopancreatobiliary surgery,we introduce seven common types of 3D printing technology and review the status of research and application of 3D printing technology in the field of hepatopancreatobiliary surgery.