Objective To study the clinical characteristics, diagnostic methods and therapeutic efficacy of pneumocystis pneumonia (PCP) in patients with acquired immunodeficiency syndrome (AIDS). Methods Sixty-nine AIDS cases of PCP were diagnosed according to the criteria of USA Centers for Disease Control and Prevention revised in 1993. The clinical symptoms and signs of the patients were observed. The peripheral blood lymphocyte counts, blood gas analysis and bronchoalveolar lavage fluid (BALF) were checked and transbronchoscopic lung biopsy was performed. Results All studied patients were in the late stage of AIDS. The main clinical manifestations included fever (100.0%), cough (97.1%), and dyspnea (92.80%). Pulmonary rales could be heard in 42 cases (60.9% ). Peripheral CD4+ T lymphocyte counts ranged from 1 × 106 -88 × 106/L. Fifty-two cases (75.4% ) had low arterial partial pressure of oxygen value of less than 10.7 kPa (1 kPa = 7.5 mm Hg). Sixty-one cases (88.4 %) had elevated serum lactate dehydrogenase (LDH) level. Bilateral diffused interstitial change (46.4%) and ground-glass shadow (29.0%) were the most common abnormal chest radiological findings. Pneumocystis organisms were detected in the BALF from 2 patients and in the transbronchial biopsy (TBB) tissue from 35 patients. All patients were treated with compound sulfamethoxazole. Thirty-three were treated with corticosteroid simultaneously and 27 were assisted with mechanical ventilation. Fifty patients recovered or got improved, eleven died, and eight left hospital because of deteriorated condition. Conclusions When an AIDS patient represents with fever, cough, dyspnea, hypoxemia, elevated serum I.DH level, CD4+ T lymphocyte count below 100 × 106/L, and interstitial pneumonia or ground-glass shadow in chest images, the diagnosis of PCP could be made presumptively. It is difficult to make a nosogenic diagnosis of PCP, but TBB considerably increases the positive rate of pneumocystis. Compound sulfamethoxazole is recommended as the first selected drug. In severe cases, corticosteroid and assisted mechanical ventilation combined with compound sulfamethoxazole could remarkably improve the prognosis of PCP.

Objective: To investigate the effect of different root canal obturation techniques on apical sealing in oval root canals. Methods: 120 recently extracted human premolars with single oval canal were randomly divided into 6 groups, including single point obturation, warm gutta percha vertical condensation, cold lateral condensation obturation method combined with different root canal sealers (iRoot SP or AH-Plus). There're six groups in total, including single point iRoot group, warm gutta percha iRoot group, cold gutta percha iRoot group, single point AH group, warm gutta percha AH group, cold gutta percha AH group. Results : Root depth of dye penetration in warm gutta percha iRoot group and warm gutta percha AH group were significantly lower than group single point iRoot group and single point AH group (P < 0.05), and root depth of dye penetration of warm gutta percha iRoot group, cold gutta percha iRoot group was less than warm gutta percha AH group, cold gutta percha group (P < 0.05), but there was no statistic difference between other groups (P > 0.05). Conclusion In root canal treatment, warm gutta-percha condensation technology can make the oval canal root achieve better sealing effect, using iRoot SP is better than using AH-Plus.

Objective: To standardize the occupational health management of radiation workers and raise the management level and technical content for the supervision of occupational health of radiation workers. Methods: The information system for radiation worker passbook was established and applied in Hebei province for practice. Results: Until December 2018, 4 339 passbooks have been issued to radiation workers from 140 medical institutions. Through the establishment and operation of the radiation worker passbook information system, the basic information and distribution characteristics of the provincial registered medical institutions and their radiation workers in Hebei province were obtained. The efficiency of the examination and approval and issuance of radiation worker certificates by the health administrative departments was improved by reducing the intermediate procedure. Conclusions Data are obtained and provided for the discussion of electronic card management of occupational health of radiation workers, real-time query of information such as medical institutions of radiation workers, education and training, individual dose monitoring, occupational health examinations, and diagnosis and identification of occupational radiological diseases. Reference basis is provided for health administrative departments to carry out radiation worker supervision.