1. HISTORY OF WESTERN ANATOMY IN MONGOLIA
Mongolian Pharmacy and Pharmacology 2013;2(1):47-
In the History of Yuan Dynasty, the 81st chapter of scripture “…Khubilai Khaan was established the Medical school in May, second year of Jun Tung”. This is certifying that first confidential hospital was formed in 1261 of public reckoning. In 1280 Mongolian State 5th article of law /one of the codes of law for 13th century were the hospitals /Military/ approved by State law during the 10-13th century, which had their strong rules and regulations. Doctor Khusekhui, a Mongolian nationality was printed the three volumes of book, which titled “Brief Practical Guide to Healthy Diet” printed in 1330. Also there are high needs to search theoretic creature about Mongolian food. Starting since 17th century Mongolian doctors, scientists were started to establish flow of “Four Medical Tantras” and based on “Astanga Hrdayam Samhita” written by famous Doctor Bagbat from Indian Auyrved /1500-1600/, “The explanation of Quintessence of the Eight Branches” his explanatory literature by Chandranandan, was compiled by sage Doctor, Elder Utog Yondongombo /729-854/ and Younger Utog Uoyndongombo reviewed again “Four Medical Tantras” during XII century. Study of personal history and works of famous Mongolian doctors and scholars is a tool for drawing historical tree of the traditional medicine. Of particular importance is period between 17th and 19th century which is a golden period of traditional medicine development. In this research project we identified the details of personal history of some scholars who had great contribution into the development of traditional medicine including Zaya Pandit Namkhaijamts from Oirad (1559), Lama Gegeen Luvsandanzanjaltsan (1639-1704), Zaya Pandit Luvsanprinlei (1642-1715), Lord Gombojav from Uzemchin (1680-1750), Arya jonlon Pandit Agvaanluvsandanbiijantsan (1770- 1845), Sube hambo Ishbaljir (1704-1788), Tsahar gevsh Luvsanchultem (1740-1810), Mindol nomuun Khan (1789-1838), Toin Jambaldorj (1792-1855), Luvsanchoimbal (19th century), Jigmeddanzanjamts (19th century), Ishdanzanvaanjil (1852-1906), Agvaangenden (19th century), Yondon (19th century), Lunrig Dandar (1831-1920), Choijamts (1860-1928). In addition, we also made observations on their works from the perspectives of theory, methodology and philosophy. Comprehending a science in light of its own methodology is important because then it opens up for observations from the perspective of other sciences and methodologies as well as creates new ideas.
2. SCREENING THE NEWBORN FOR DYSPLASIA OF THE HIP
Tungalag L ; Bilegjargal CH ; Uranchimeg D ; Ariunjargal B
Innovation 2015;9(3):55-56
Developmental Dysplasia of the Hip (DDH) is a major health problem which can lead to lifelong handicapped condition of individuals if early diagnosis is missed. Cost for treatment, surgery and rehabilitation of these cases is much higher than that for prevention. According to Graf, hip ultrasound screening method is simple, reproducible, innocuous and can be performed by well- trained neonatologists. The purpose of this study is to determine prevalence and types of hip dysplasia by Graf standard screening method. A prospective study was carried out. Hip ultrasound screening using Graf method was performed by neonatologists at the Amgalan of maternity of the Capital city from January 2013 to March 2015.Totally 6154 neonates were eligible for the study and 50.9% of them were male, 93.27% term and 6.72% preterm, in 8.53% of babies, type IIa (physiological retardation of ossification)was found. Dysplasia or dislocation of hips (type III and IV) was found in 5 (0.08%) neonates. Babies diagnosed with type I on both hips were discharged. Type IIa cases were stopped being swaddled and reassessed after 4 weeks. Cases with type III and IV cases were all treated with abduction treatment or Tubinger. This study is an ongoing project. The implementation of the hip ultrasound screening according to Graf is feasible and can be performed by well-trained neonalogists in Amgalan of maternity of the Capital city.
3.Comparative in vitro quality evaluation of Metronidazole tablets
Azjargal G ; Tungalag Ts ; Otgonchimeg T ; Gereltuya D
Mongolian Pharmacy and Pharmacology 2024;24(1):57-62
Introduction:
Quality of pharmaceutical products is very important because drugs must be marketed as safe
and therapeutically active formulations whose performance is consistent and predictable. The evaluation of
the physical characteristics of the pharmaceutical products can ensure their quality as well as bioavailability
and impart optimum therapeutic activity. Metronidazole was chosen for this comparative study because this
drug is widely used worldwide in the treatment of amoebiasis and other microbial diseases.
Method:
The quality control parameters of five different brands of metronidazole 500 mg tablets were
determined weight variation, friability, hardness, and disintegration, dissolution and assay tests. All the tablets
were evaluated for conformity with British Pharmacopoeia (BP) and Mongolian Pharmacopoeia-National
Formulary (MP-NF) standards.
Results:
Among five brands of tablets Brand М3 had lower mean weight variation of 0.8% and Brand М1
had highest mean weight variation of 3.42%. For friability test Brand М2 had the lowest mean friability (0.57)
and Brand М1 had highest mean friability (1.51). The disintegration time for five brands of ciprofloxacin tablet
obtained were in the subsequent order: Brand М1 (2.82 min) < Brand М3 (8.8 min) < Brand М4 (12.32 min)
< Brand М5 (13.82 min) < Brand М1 (39.22 min).
Conclusion
The present study revealed that all of the leading brands (M1, M2, M3, M4, M5) of this tablet
met the quality control parameters as per pharmacopoeial specifications.
4.Food poisoning infection caused by Salmonella spp
Tungalag O ; Enerel E ; Dagvadorj Ts ; Narangerel B ; Lkhagvadorj D ; Altantsetseg D
Mongolian Medical Sciences 2019;190(4):3-7
Background:
We aimed to study the etiology and transmission route of diseases introducing the modern, rapid and
high-sensitivity molecular genetic diagnostic methods for salmonellosis.
Material and Method:
In the study, we collected 680 stool samples and defined organisms of food intoxication by identification
of bacteria, polymerase chain reaction (PCR) and determined serotype and antibiotic resistance.
Result:
Salmonella spp was detected from the stool of 25 (42.3%) patients out of 59 outpatient clinic and
of 170 (27.4%) patients out of 621 inpatient clinic with diagnosis of food intoxication. In total there
was detected 195 salmonella spp, and out of this isolated Sal. typhimurum in 193 (98.9%), and Sal.
enteritidis was in 2 (1.1%) patients, respectively. We defined Sal. typhimurum in selected 32 cultures
and did not detect resistant gene DT-104 ACS-SuT by PCR.
Conclusion
As resulted in the survey, we defined 195 (28,6) Salmonella typhimurum among the 680 patients who
were suffered from food intoxication, and revealed fast foods, animal derived foods such as chicken,
fish caused the food intoxication. Sal. typhimurium not resistance to antibiotics.
5.Elucidating the uses of the plant Veronica Incana from the ancient medical books
Sansarkhuyag E ; Ariunjargal T ; Tungalag D ; Selenge E ; Odontuya G ; Bold Sh
Mongolian Pharmacy and Pharmacology 2023;23(2):5-11
Background:
In 2011-2020, WHO approved the Global Strategy for Traditional Medicine. The strategy states that "The
trend of using traditional medicine and alternative medicine as a source and resource for health care is
expanding worldwide."
In this regard, it is important to develop a policy and methodology to develop a proper combination of traditional and modern medicine. Also, there are demands to study and solve the problems of ensuring the safe, effective, quality, availability, and appropriate use of medicines and treatments.
Purpose:
Finding traditional medicinal recipes containing the herb Veronica incana L from the ancient Mongolian
medical books written by famous Mongolian scientists Jambalchoizhidanzanperenlei, Luvsandorj, and
Jigmeddanzanjamts.
Research materials and methods:
1. Research materials: Jambalchoijidanzanperenlei. gso rig bstan bcos mtha' dag gi snying po rnams phyogs gcig tu bsdus pa man ngag rin chen 'byung gnas bzhugs so. Wooden printing block with Tibetan script. Luvsandorj. sman sbyar tshad kyi skor rnams che long tsam phyogs gcig tu bkod ba kun phan bdud rtsi'i snying bo zhes bya ba bzhugs so). Wooden printing block with Tibetan script. Jigmeddanzanjamts. rgya badmkhas grub du ma'i gzhung lugs dam pa gong ma rnams kyi man ngag zhal shes lag len myong grub gnad don gnyen po ngo sprod mdzub tshugs dmar khrid kyi bkod pa mthong ba don gsal dga' byed snying po'i rnam gsal bzhugs so. Wooden printing block with Tibetan script.
2. Research methods: Methods of textual analysis for ancient books and checklist methods were used in the study.
Conclusion
Medicinal recipes containing the herb Veronica Incana L were sampled from the ancient medical books surveyed. There are 6 recipes in the book of Jambalchojidanzanperenlei, 3 recipes in the book of Luvsandorj, and 2 in the book of Jigmeddanzanjamts, a total of 11 ingredients. In general, these ancient medical books had a significant impact on the development of traditional Mongolian medicinal prescriptions. Therefore, even today, these works are still important in the theory of pharmaceutical composition and the practice of drug therapy.
6.Elucidating the uses of the plant Veronica Incana L from the ancient medical books
Sansarkhuyag E ; Ariunjargal V ; Tungalag D ; Selenge E ; Odontuya G ; Bold Sh
Mongolian Pharmacy and Pharmacology 2023;23(2):26-32
Background:
Medicinal plant research has been successfully carried out in the field of pharmacy and pharmacology
in Mongolia, and dozens of research projects are still being carried out However, there are still fewer
studied medicinal plants of practical importance growing in Mongolia. Therefore, there is a need to register and study the ancient medicinal books written by ancient Mongolian doctors about the relatively lilUe-studied Veronica Incana L plant. In addition, taking into account that scientific research on Veronica Incana L. which grows in Mongolia, has not been done in the field of medicine, the topic was selected for research in this field.
Purpose:
Comparing the information of the ancient medical books written by Mongolian doctors and scientists,
who wrote about Veronica Incana L, to clarify the taste, power, and quality
Research materials and methods:
1. Research materials: Sumbe khamba Ishoaljir. gso dpyad bdud rtsi 'i chu rgyun gyi cha lag gi nang tshan gyi sman so so'i mngon brjod dang ngos 'dzin shel dkar me long. Wooden printing block with Tibetan schpl. Toin Jambaldorj. gso byed bdud rtsi'i 'khrul med ngos 'dzin bzo rig me long du rnam par
shar ba mdzes mtshar mig rgyan zhes bya ba bzhugs so. Wooden printing block with Tibetan script.
2. Research methods: Methods of textual analysis for ancient books and checklist methods were used in the study.
Conclusion
Gandhabhatra plant is used in traditional Mongolian medicinal practice from ancient times, the plant
is called Veronica Incana L in Lalin. Also called Buural gandbadraa in Mongolian. On the other hand,
the traditional medical doctors of China's Inner Mongolia and Tibet use Gandbadraa, the Latin name
Gnaphalium affine D. Don. The appearance, shape, and color of the flowers of these two plants are
different According to the research of the source, the main instruction and usage of the plants are the
same: to deslroy benign tumors, lo remove poison, to treat colds, and to stop cough.