1.Role of animal models in biomedical research: a review
P. MUKHERJEE ; S. ROY ; D. GHOSH ; S. K. NANDI
Laboratory Animal Research 2022;38(3):132-148
The animal model deals with the species other than the human, as it can imitate the disease progression, its’ diagnosis as well as a treatment similar to human. Discovery of a drug and/or component, equipment, their toxicological studies, dose, side effects are in vivo studied for future use in humans considering its’ ethical issues. Here lies the importance of the animal model for its enormous use in biomedical research. Animal models have many facets that mimic various disease conditions in humans like systemic autoimmune diseases, rheumatoid arthritis, epilepsy, Alzheimer’s disease, cardiovascular diseases, Atherosclerosis, diabetes, etc., and many more. Besides, the model has tremendous importance in drug development, development of medical devices, tissue engineering, wound healing, and bone and cartilage regeneration studies, as a model in vascular surgeries as well as the model for vertebral disc regeneration surgery. Though, all the models have some advantages as well as challenges, but, present review has emphasized the importance of various small and large animal models in pharmaceutical drug development, transgenic animal models, models for medical device developments, studies for various human diseases, bone and cartilage regeneration model, diabetic and burn wound model as well as surgical models like vascular surgeries and surgeries for intervertebral disc degeneration considering all the ethical issues of that specific animal model. Despite, the process of using the animal model has facilitated researchers to carry out the researches that would have been impossible to accomplish in human considering the ethical prohibitions.
2.Medicine prescription practices of homeopathic undergraduate students in West Bengal, India.
Subhranil SAHA ; Munmun KOLEY ; Jogendra Singh ARYA ; Gurudev CHOUBEY ; Shubhamoy GHOSH ; Subhasish GANGULY ; Aloke GHOSH ; Sangita SAHA ; Malay MUNDLE ; E-mail: DRMALAYMUNDLE@GMAIL.COM.
Journal of Integrative Medicine 2014;12(1):7-12
OBJECTIVETo our knowledge, prescription of homeopathic medicines by homeopathic undergraduate students has not been studied before though it may possess serious implications. We aimed to determine the practice and attitudes of prescription by homeopathic undergraduate students.
METHODSA cross-sectional study was carried out involving all the students from four government homeopathic schools of West Bengal, India. Ethical requirements were ensured and data were collected using self-administered questionnaires. Chi-square tests and logistic univariate regression analyses were performed to identify associations and differences.
RESULTSA total of 328 forms were completed. Of these, 264 (80.5%) homeopathic undergraduate students admitted of prescribing medicines independently and most (40.5%) said that they did this 2-3 times a year. The most common reasons for this were 'urgency of the problem' (35.2%), 'previous experience with same kind of illness' (31.8%), and 'the problem too trivial to go to a doctor' (25.8%). About 63.4% of the students thought that it was alright to independently diagnose an illness while 51.2% thought that it was alright for them to prescribe medicines to others. Common conditions encountered were fever, indigestion, and injury. Students who prescribed medicines were more likely to belong to Calcutta Homeopathic Medical College and Hospital (odds ratio = 5.8; 95% confidence interval 2.247-14.972). Prescription by students gradually increased with academic years of homeopathic schools. Many students thought it was alright for students to diagnose and treat illnesses.
CONCLUSIONPrescription of medicines by homeopathic undergraduate students is quite rampant and corrective measures are warranted.
Adult ; Cross-Sectional Studies ; Drug Prescriptions ; standards ; statistics & numerical data ; Female ; Homeopathy ; education ; manpower ; standards ; Humans ; India ; Male ; Students ; statistics & numerical data ; Surveys and Questionnaires ; Young Adult
3.A Comprehensive View on the Progress of Organoid Research with an Emphasis on its Relevance to Disease Characterization.
Chandra KISHORE ; Vaishali JI ; Saurav MALLIK ; Ayan MUKHERJI ; Namrata TOMAR ; Kumar Pati SOUMEN ; Ai Min LI ; Sinthia Roy BANERJEE ; Soumadip GHOSH ; Raza Ali NAQVI
Biomedical and Environmental Sciences 2023;36(10):959-971