Cytomegalovirus (CMV) infection commonly affects patients who are in an immunocompromised state, such as acquired immune deficiency syndrome (AIDS) and during organ transplantation. Although cytomegalovirus infection does not occur frequently, it is a major cause of morbidity and mortality in patients suffering with connective tissue diseases, including dermatomyositis. Cytomegalovirus pneumonitis and retinitis has been rarely reported in patients with dermatomyositis. We report here on an usual case involving the simultaneous occurrence of cytomegalovirus pneumonitis and retinitis in a 39-year-old female with dermatomyositis, and this woman had been treated with steroids and immunosuppressive agents for the previous 5 months.
Acquired Immunodeficiency Syndrome ; Adult ; Connective Tissue Diseases ; Cytomegalovirus ; Cytomegalovirus Infections ; Cytomegalovirus Retinitis ; Dermatomyositis ; Female ; Humans ; Immunosuppressive Agents ; Organ Transplantation ; Pneumonia ; Retinitis ; Steroids ; Stress, Psychological ; Transplants

Cytomegalovirus retinitis (CMV), an opportunistic infection of a immunocompromised patient, is a necrotizing retinitis occurred in AIDS or the patient using immunosuppressants. A 31-years-old male taken immunosuppressants after renal transplantation, had white granular foci and perivascular sheathings in the uper temporal retina of both eyes. Serologic test demonstrated positive response to bith IgG and IgM antibody against CMV. Argon laser photocoagulation was done and ganciclovir was intravenously treated 300 mg every 12 hours for three weeks without maintenance therapy. Nine months after treatment, there was no recurrence of retinitis. This result suggests CMV retinitis of renal transplanted patient may not need the maintenance therapy of ganciclovir.
Argon ; Cytomegalovirus Retinitis* ; Cytomegalovirus* ; Ganciclovir* ; Humans ; Immunocompromised Host ; Immunoglobulin G ; Immunoglobulin M ; Immunosuppressive Agents ; Kidney Transplantation ; Light Coagulation ; Male ; Opportunistic Infections ; Recurrence ; Retina ; Retinitis ; Serologic Tests

Cytomegalovirus(CMV) ocular infection is one of the common ocular complications seen in immunocompromised condition, such as AIDS or organ transplant recipient receiving immunosuppressive drugs, CMV papillitis is known to be care. CMV papillitis has, however, a poor visual prognosis because the treatment is more resistant to than that of CMV retinitis. We report a case of CMV papillitis after the renal transplantation which has good result with long-term ganciclovir administration.
Cytomegalovirus ; Eye Infections ; Ganciclovir ; Kidney Transplantation ; Papilledema* ; Prognosis ; Retinitis ; Transplantation* ; Transplants

No abstract available.
Cytomegalovirus Infections* ; Cytomegalovirus*

No abstract available.
Cytomegalovirus Infections* ; Cytomegalovirus* ; Incidence*

No abstract available.
Cholestasis* ; Cytomegalovirus Infections* ; Cytomegalovirus*

No abstract available.
Cytomegalovirus Infections* ; Cytomegalovirus*

No abstract available.
Cytomegalovirus Infections* ; Cytomegalovirus*

Cytomegalovirus (CMV) is a major cause of morbidity and mortality in immunocompromised patients. CMV can cause pneumonia, retinitis, gastrointestinal ulcers, and widely disseminated disease, but cutaneous CMV is rare. We report two cases of cutaneous CMV infection presenting as perianal ulcers. A 54 year-old male who had liver transplantation and a 72-year-old male, who was treated with chemotherapy for angioimmunoblastic T-cell lymphoma, presented with perianal ulcers and had systemic symptoms of CMV infection with CMV antigenemia. They had multiple ulcerations with erythematous bases on the perianal area, and histopathologic examinations showed large atypical cytomegalic cells in the dermis, and immunohistochemical stains, with the anti-CMV antibody showed positive reactions.
Aged ; Coloring Agents ; Cytomegalovirus Infections* ; Cytomegalovirus* ; Dermis ; Drug Therapy ; Humans ; Immunocompromised Host* ; Liver Transplantation ; Lymphoma, T-Cell ; Male ; Mortality ; Pneumonia ; Retinitis ; Ulcer

The human cytomegalovirus (CMV), a member of the herpes virus family, can cause a lifelong infection with episodes of endogenous reactivation. Almost the entire adult Korean population has been infected with CMV; they have serum CMV antibodies of IgG class. Reactivation is clinically silent in immunocompetent individuals. Symptomatic illness, such as pneumonitis, retinitis, hepatitis or gastroenteritis, is usually confined to immunocompromized patients. The colon, stomach and esophagus are the organs frequently infected with CMV in these patients. A CMV infection may also complicate an inflammatory bowel disease. CMV enteritis involving the small bowel, which makes up less than 10% of the CMV gastroenteritis cases, usually presents with diarrhea, bleeding and perforation, but rarely evokes obstruction. The authors experienced a case of CMV enteritis of the terminal ileum, presenting as an intestinal obstruction, which developed in an immunocompetent individual with no underlying disease. This appears to be a world first.
Adult ; Antibodies ; Colon ; Cytomegalovirus Infections* ; Cytomegalovirus* ; Diarrhea ; Enteritis ; Esophagus ; Gastroenteritis ; Hemorrhage ; Hepatitis ; Humans ; Ileum ; Immunoglobulin G ; Inflammatory Bowel Diseases ; Intestinal Obstruction ; Pneumonia ; Retinitis ; Stomach