2.High-Dose Cytosine Arabinoside (HD Ara-C) Therapy for Refractory Acute Leukemia in Children.
Il Soo HA ; Hyo Seop AHN ; Chang Yee HONG
Journal of the Korean Pediatric Society 1988;31(10):1328-1337
No abstract available.
Child*
;
Cytarabine*
;
Cytosine*
;
Humans
;
Leukemia*
3.Salvage chemotherapy with R-BAD (rituximab, bendamustine, cytarabine, and dexamethasone) for the treatment of relapsed primary CNS lymphoma.
Min Seok CHO ; Jae Yong KIM ; Seung Yeon JUNG ; Seo Yeon AHN ; Ga young SONG ; Deok Hwan YANG
Blood Research 2016;51(4):285-287
No abstract available.
Bendamustine Hydrochloride*
;
Cytarabine*
;
Drug Therapy*
;
Lymphoma*
4.Intrapleural chemotherapy with cisplatin and cytarabine in the management of malignant pleural effusion.
Korean Journal of Medicine 2000;58(2):250-252
No abstract available.
Cisplatin*
;
Cytarabine*
;
Drug Therapy*
;
Pleural Effusion, Malignant*
5.The Effect of Subconjunctival Injection of Liposome Encapsulated Cytarabine on Proliferation of Fibroblasts.
Gong Je SEONG ; Young Jae HONG ; Seong Jun PARK
Journal of the Korean Ophthalmological Society 1992;33(9):885-891
To know the effect of subconjunctival injection of liposome encapsulated cytarabine on proliferation of conjunctival fibroblasts, the conjunctiva was isolated at 180 degrees from the injection site 3 days after subconjunctival injection of the normal saline (control), cytarabine, liposome encapsulated cytarabine, and 1 day after injection of cytarabine, and then those were inoculated in the culture media of fibroblasts. In the case of 3 days after injection of cytarabine, there was 49% and 42% inhibition of proliferation of conjunctival fibroblasts compared with the control respectively. Therefore, the authors concluded that the liposome encapsulated cytarabine is effective on inhibition of proliferation of conjunctival fibroblasts and reduces the frequencies of subconjunctival injection compared with the cytarabine itself.
Conjunctiva
;
Culture Media
;
Cytarabine*
;
Fibroblasts*
;
Liposomes*
6.Treatment of myelodysplasia syndrome
Journal of Medical and Pharmaceutical Information 2003;0(5):16-22
Myelodysplasia syndrome is a diseases group of which quite
difficult cure and prediction. There are many treatment methods however it depends on patient’s age, level of diease, rate of blast in bone marrow. The treatment includes: chemical treatment, trasplant originative cell, support treatment. Other method is combination of various treatment methods: Use Ara-C combine with depersolon, chemical treatment combine with stimulative agent of blood and trasplant originative cell
Neural Tube Defects
;
Bone Marrow
;
Cytarabine
;
Therapeutics
7.Mitoxantrone and cytosine arabinoside in adult patients with refractory and relapsed acute leukemia.
Jae Yong LEE ; Hyun Choon SHIN ; Young Suk PARK ; Jung Soon JANG ; Young Hyuck IM ; Sung Soo YOON ; Seoun Yang PARK ; Byoung Kook KIM ; Noe Kyeong KIM
Korean Journal of Hematology 1993;28(2):257-265
No abstract available.
Adult*
;
Cytarabine*
;
Cytosine*
;
Humans
;
Leukemia*
;
Mitoxantrone*
8.Combination chemotherapy with TAD(6-thioguanine, Ara-C and daunorubicin) in acute myelogenous leukemia.
Hong Seok AHN ; Yong Cheol LEE ; Chang Hun PARK ; Chang Yeol YIM
Korean Journal of Hematology 1991;26(1):73-80
No abstract available.
Cytarabine*
;
Drug Therapy, Combination*
;
Leukemia, Myeloid, Acute*
9.Analysis of Clostridium difficile-associated Diarrhea in Kumiai Hospital
Toshiyuki YOKOYAMA ; Yumiko YOKOYAMA ; Toru ARAI
Journal of the Japanese Association of Rural Medicine 2005;54(1):28-36
Clostridium difficile (C. difficile) is one of the important pathogens which cause antibiotic-associated diarrhea (AAD) -diarrhea following antibiotic therapy. There are some reports of nosocomial outbreak of AAD caused by C. difficile.We analyzed risk factors and epidemiology of C. difficile-associated diarrhea (CAD) in Kumiai Hospital. From March 2003 to February 2004, 53 in patients developed AAD, of whom 35 patients (66%) were diagnosed as having CAD. Advanced age, bed-rest, tube-feeding, and prolonged administration of antibiotics were regarded as risk factors.In initial two months, seven cases developed CAD in one ward and five in another ward. After hand-washing and use of gloves were enforced in treating CAD patients, the incidence of CAD decreased. Epidemiological analysis was performed using PCR ribotyping of C. difficile strains recovered from 20 among 35 CAD cases in the different wards. Nineteen of 20 strains were identical, typed as the ribotype. These results may suggest nosocomial diarrhea but we cannot conclude that is a hospital infection as yet.Although all C. difficile strains recovered in this study were toxin A-positive, the result of the test using a toxin A detecting kit was negative in three cases. It is necessary toculture C. difficile in addition to detecting toxin A to diagnose CAD.
cytarabine/daunorubicin
;
Carbon ion
;
Diarrhea
;
Clostridium difficile
;
Toxins
10.The influence of Ara-C on anti-CD3/anti-Pgp mediating T-lymphocytes activities against multi-drug resistant leukemia cells..
Ming YANG ; Dong-Mei FAN ; Ying-Dai GAO ; Yuan ZHOU ; Qing JI ; Xiao-Feng SHAO ; Jin-Hong WANG ; Yuan-Fu XU ; Dong-Sheng XIONG ; Chun-Zheng YANG
Chinese Journal of Hematology 2009;30(12):812-815
OBJECTIVETo investigate the role of Ara-C in regulating anti-CD3/anti-Pgp mediating T-lymphocytes activities against multi-drug resistant leukemia cells.
METHODSThe diabody of anti-CD3/anti-Pgp was purified by E-tag affinity chromatography. K562 and K562/A02 cells were treated with Ara-C. The expressions of B7-1 and B7-2 on K562 and K562/AO2 cells were detected by FACS. The cytotoxicity of T-lymphocytes combined with anti-CD3/anU-Pgp plus Ara-C was analyzed by CytoTox 96 nonradioactive method.
RESULTSThe expressions of B7-1 and B7-2 on K562 and K562/A02 cells treated by Ara-C was significantly higher than those untreated. The effect/target ratio was from 0.39:1 to 25:1, and the killing rate of activated T cells to anti-drug-resistant leukemia cells was from (16.44 +/- 1.20)% to (60.49 +/- 2.90)%. The killing rates were increased gradually, with both the effect/target ratio and the antibody concentration increasing (P < 0.05).
CONCLUSIONAra-C may be an important adjuvant for improving anti-CD3/anti-Pgp mediating T-lymphocytes activities against multi-drug resistant leukemia cells.
Cytarabine ; Humans ; K562 Cells ; Leukemia ; immunology ; T-Lymphocytes ; immunology