Cystic neoplasm of the pancreas is a relatively uncommon condition covering a wide spectrum of pathology. The increasing incidence as a result of routine imaging tests in asymptomatic patients presents a diagnostic and therapeutic problem to the clinician. This paper discusses the role of the various investigative modalities in the management of cystic neoplasia of the pancreas.
Cystadenoma ; diagnosis ; therapy ; Pancreatic Neoplasms ; diagnosis ; therapy

OBJECTIVE: This study was designed to determine the clinical significance of serum CA 125 and CA 19-9 levels in preoperative differential diagnosis of benign ovarian tumors. METHODS: 104 patients who visited the department of Obstetrics and Gynecology of Dankook University Hospital from February 1999 to December 2001, and who were diagnosed as adnexal mass and underwent surgery, and free of other medical diseases, were enrolled as subjects. An analysis of preoperative serum CA 125, CA 19-9 levels of patients was performed in correlation with the postoperative histologic diagnoses. The histologic diagnoses were grouped as mature cystic teratoma, endometrioma, mucinous cystadenoma, serous cystadenoma, benign cystic tumor group, adnexal inflammatory disease group. Study group was defined as endometrioma, adnexal inflammatory disease in CA 125, and mature cystic teratoma, endometrioma in CA 19-9, and the others were defined as control group. Statistical analysis with Chi square test was done on the number of cases who showed CA 125 or CA 19-9 increment over cut off value between study group and control group. Study group was compared with control group in the mean value of serum tumor marker level and the mean value of elevated serum tumor marker level over cut off value. RESULTS: The number of cases who showed serum CA 125 increment over cut off value (35 U/ml) was significantly higher in endometrioma and adnexal inflammatory disease group (p<0.05), and the number of cases who showed serum CA 19-9 increment over cut off value (37 U/ml) was significantly higher in endometrioma and mature cystic teratoma group (p<0.05). The mean value of serum tumor marker level and the mean value of elevated serum tumor marker level over cut off value in those groups showed no significant difference in comparison with those of the other groups. CONCLUSION: In this study, increment of CA 19-9 in endometrioma and CA 125 and CA 19-9 in mature cystic teratoma showed statistically significant higher frequency than other groups. We concluded that checking the preoperative serum level of CA 125 and CA 19-9, combined with transvaginal ultrasonography, may be helpful in differential diagnosis of benign ovarian tumors and in discriminating benign ovarian tumors from malignant ovarian tumors, if any other condition that may cause serum level elevation of CA 125 and CA 19-9 is excluded.
Cystadenoma, Mucinous ; Cystadenoma, Serous ; Diagnosis ; Diagnosis, Differential ; Endometriosis ; Female ; Gynecology ; Humans ; Obstetrics ; Teratoma ; Biomarkers, Tumor* ; Ultrasonography

The purpose of this prospective study was to evaluate the diagnostic value of color Doppler scoring system in characterization of ovarian masses. We performed transabdominal or transvaginal color Doppler sonopaphy on 82 women with ovarian masses and analyzed the sonographic findings. Ovarian lesions were assessed by means of morphological and color Doppler scoring system by Kurjak. Tumors were characterized by ultrasonographic findings as benign or suspected of being malignant. Then the results of each scoring systems were correlated with histopathological findings. The results were as follows; Of 82 ovarian masses, 64 were benign lesions(13 mucinous cystadenomas, 16 endometriomas, 20 teratomas, 8 serous cystadenomas, and 13 other abnormalities), and 18 were malignant(12 cancers and 6 borderline tumors). The color Doppler scoring system was useful in distinguishing malignant from benign masses, with a sensitivity of 88.2%, compared with the morphological scoring system of 86.7%. The specificity of color Doppler and morphological scoring system were 95.4% and 92.5%, respectively. The sensitivity of combination of both scoring systems was 88.9%, with a specificity of 96.9%. In conclusion, color Doppler scoring system is a useful tool in predicting the malignancy of ovarian lesions especially combined with morphological scoring system.
Cystadenoma, Mucinous ; Cystadenoma, Serous ; Diagnosis* ; Endometriosis ; Female ; Humans ; Prospective Studies ; Sensitivity and Specificity ; Teratoma ; Ultrasonography

Cystadenoma rarely arises in the parotid gland. It grows slowly without pain. Histopathologically, it is subdivided into papillary cystadenoma and mucinous cystadenoma. Mucinous cystadenoma arising from the salivary gland is a very rare benign tumor. A 25-year-old female patient visited our hospital with a left infra-auricular mass. Computed tomography scan showed a 3.1x2.3 cm size heterogeneous lesion with an irregular margin in the left parotid gland. Sono guided gun biopsy was performed to reveal fibrous tissue with atypical epithelial cell with mucin. Suspecting mucoepidermoid carcinoma, partial parotidectomy was performed for treatment and diagnosis. Histopathologic exam revealed mucinous cystadenoma. Cystadenoma of salivary gland has no distinct clinical feature, and is difficult to differentiate clinically from other salivary gland tumors as well as its malignancy. Thus, the possibility of malignancy must be considered for differential diagnosis.
Adult ; Biopsy ; Carcinoma, Mucoepidermoid* ; Cystadenoma ; Cystadenoma, Mucinous* ; Cystadenoma, Papillary ; Diagnosis ; Diagnosis, Differential ; Epithelial Cells ; Female ; Humans ; Mucins* ; Parotid Gland* ; Salivary Glands

No abstract available.
Cystadenoma, Serous* ; Diagnosis* ; Endoscopic Ultrasound-Guided Fine Needle Aspiration*

Simple liver cysts are common and benign lesions, and most of them are detected by ultrasonography (US) or computed tomography (CT) during a medical checkup. Because simple liver cysts are generally asymptomatic, they do not require treatment, although hemorrhage, infection or rupture may occur in rare cases and these cases must receive proper treatment. The diagnosis of simple liver cysts is usually easy because of their typical morphological findings on US or CT. However, when a liver cyst contains hemorrhage or it is inflamed on imaging studies, it is sometimes difficult to differentiate simple hepatic cysts from such conditions as cystadenoma and cystadenocarcinoma. In this report, we describe a case of simple liver cyst that was complicated by intracystic hemorrhage, and this malady was initially diagnosed as biliary cystadenocarcinoma. We successfully treated this lesion by left lateral segmentectomy.
Cystadenocarcinoma ; Cystadenoma ; Diagnosis ; Hemorrhage* ; Liver ; Mastectomy, Segmental ; Rupture ; Ultrasonography

Adrenal cysts are a rare disease, and its prevalence is reported to be 0.06~0.18%. Its frequency of being recognized is increasing due to the widespread use of ultrasonography and computed tomography (CT) scans. We report here on a case of adrenal cyst that was mistaken as biliary cystadenoma prio-ocation and features. Laparoscopic exploration was performed via the transabdominal approach and this revealed a right adrenal cystic mass in the retroperitoneum beneath the liver (segment IV). We present here a case of adrenal cyst with endothelial lining along with a review of the literature to address the clinical presentation, histology, imaging features and differential diagnosis of this interesting and rare entity.
Cystadenoma* ; Diagnosis, Differential ; Laparoscopy ; Liver ; Prevalence ; Rare Diseases ; Ultrasonography

The rete ovarii is a rare site for tumor development. We present a case of cystadenoma originating from the rete ovarii of a 58-year-old woman. It was a unilocular cyst of 7.0 cm in size, lined by flat, cuboidal, or columnar epithelial cells supported by fibromuscular tissue. Papillary growth and crevice formation of the inner surface were characteristic. The presence of a normal rete ovarii was helpful in correct diagnosis.
Cystadenoma* ; Diagnosis ; Epithelial Cells ; Female ; Humans ; Middle Aged

Ovarian serous tumors of low malignant potential (borderline serous tumors) are intermediate in their clinical behavior between benign serous cystadenoma and malignant neoplasm, and are associated with 10 year survival rates in excess of 90%. Borderline ovarian serous tumors are characterized by absence of stromal invasion but presence of some characteristics of malignancy. Borderline ovarian tumors occur predominantly in premenopausal women, and associated with a very good prognosis. The principal treatment of borderline malignancy is surgical resection of the primary tumor. But approximatley 20% of patients with ovarian tumors of low malignant potential present with Stage III or IV disease at the time of diagnosis. The benefit of postsurgical therapy in this group of patients has not been well established. We report two cases of advanced ovarian serous borderline tumor, one of which was treated with 3 cycles of cisplatin-taxol chemotherpy.
Cystadenoma, Serous ; Diagnosis ; Female ; Humans ; Prognosis ; Survival Rate

We experienced a huge ovarian tumor of 16kg, measured 29 x 25 x 30cm in 85 years old woman. Pathologic diagnosis was mucinous cystadenoma, borderline malignancy of right ovary. We present this case with brief review of literatures.
Aged, 80 and over ; Cystadenoma, Mucinous ; Diagnosis ; Female ; Humans ; Ovary