1.Cystic neoplasms of the pancreas: current diagnostic modalities and management.
Dennis Z W NG ; Brian K P GOH ; Elizabeth H W THAM ; Stephanie M YOUNG ; London Lucien P J OOI
Annals of the Academy of Medicine, Singapore 2009;38(3):251-259
Cystic neoplasm of the pancreas is a relatively uncommon condition covering a wide spectrum of pathology. The increasing incidence as a result of routine imaging tests in asymptomatic patients presents a diagnostic and therapeutic problem to the clinician. This paper discusses the role of the various investigative modalities in the management of cystic neoplasia of the pancreas.
Cystadenoma
;
diagnosis
;
therapy
;
Pancreatic Neoplasms
;
diagnosis
;
therapy
2.Clinical Significance of Serum CA 125, CA 19-9 as Tumor Markers in Benign Ovarian Tumors.
Korean Journal of Obstetrics and Gynecology 2003;46(2):306-311
OBJECTIVE: This study was designed to determine the clinical significance of serum CA 125 and CA 19-9 levels in preoperative differential diagnosis of benign ovarian tumors. METHODS: 104 patients who visited the department of Obstetrics and Gynecology of Dankook University Hospital from February 1999 to December 2001, and who were diagnosed as adnexal mass and underwent surgery, and free of other medical diseases, were enrolled as subjects. An analysis of preoperative serum CA 125, CA 19-9 levels of patients was performed in correlation with the postoperative histologic diagnoses. The histologic diagnoses were grouped as mature cystic teratoma, endometrioma, mucinous cystadenoma, serous cystadenoma, benign cystic tumor group, adnexal inflammatory disease group. Study group was defined as endometrioma, adnexal inflammatory disease in CA 125, and mature cystic teratoma, endometrioma in CA 19-9, and the others were defined as control group. Statistical analysis with Chi square test was done on the number of cases who showed CA 125 or CA 19-9 increment over cut off value between study group and control group. Study group was compared with control group in the mean value of serum tumor marker level and the mean value of elevated serum tumor marker level over cut off value. RESULTS: The number of cases who showed serum CA 125 increment over cut off value (35 U/ml) was significantly higher in endometrioma and adnexal inflammatory disease group (p<0.05), and the number of cases who showed serum CA 19-9 increment over cut off value (37 U/ml) was significantly higher in endometrioma and mature cystic teratoma group (p<0.05). The mean value of serum tumor marker level and the mean value of elevated serum tumor marker level over cut off value in those groups showed no significant difference in comparison with those of the other groups. CONCLUSION: In this study, increment of CA 19-9 in endometrioma and CA 125 and CA 19-9 in mature cystic teratoma showed statistically significant higher frequency than other groups. We concluded that checking the preoperative serum level of CA 125 and CA 19-9, combined with transvaginal ultrasonography, may be helpful in differential diagnosis of benign ovarian tumors and in discriminating benign ovarian tumors from malignant ovarian tumors, if any other condition that may cause serum level elevation of CA 125 and CA 19-9 is excluded.
Cystadenoma, Mucinous
;
Cystadenoma, Serous
;
Diagnosis
;
Diagnosis, Differential
;
Endometriosis
;
Female
;
Gynecology
;
Humans
;
Obstetrics
;
Teratoma
;
Biomarkers, Tumor*
;
Ultrasonography
3.Contribution of Color Doppler Scoring System to Diagnosis of Ovarian Malignancy.
Duk Soo BAE ; Jong Dae WHANG ; Seon Hye PARK ; Bo Hyun KIM ; In Sook JOO ; Chang Soo PARK ; Je Ho LEE
Korean Journal of Gynecologic Oncology and Colposcopy 1997;8(3):271-278
The purpose of this prospective study was to evaluate the diagnostic value of color Doppler scoring system in characterization of ovarian masses. We performed transabdominal or transvaginal color Doppler sonopaphy on 82 women with ovarian masses and analyzed the sonographic findings. Ovarian lesions were assessed by means of morphological and color Doppler scoring system by Kurjak. Tumors were characterized by ultrasonographic findings as benign or suspected of being malignant. Then the results of each scoring systems were correlated with histopathological findings. The results were as follows; Of 82 ovarian masses, 64 were benign lesions(13 mucinous cystadenomas, 16 endometriomas, 20 teratomas, 8 serous cystadenomas, and 13 other abnormalities), and 18 were malignant(12 cancers and 6 borderline tumors). The color Doppler scoring system was useful in distinguishing malignant from benign masses, with a sensitivity of 88.2%, compared with the morphological scoring system of 86.7%. The specificity of color Doppler and morphological scoring system were 95.4% and 92.5%, respectively. The sensitivity of combination of both scoring systems was 88.9%, with a specificity of 96.9%. In conclusion, color Doppler scoring system is a useful tool in predicting the malignancy of ovarian lesions especially combined with morphological scoring system.
Cystadenoma, Mucinous
;
Cystadenoma, Serous
;
Diagnosis*
;
Endometriosis
;
Female
;
Humans
;
Prospective Studies
;
Sensitivity and Specificity
;
Teratoma
;
Ultrasonography
4.A Case of Mucinous Cystadenoma Mimicking Mucoepidermoid Carcinoma in Parotid Gland.
Namhyung RYOU ; Dong Yn KO ; Hwaejoon JUNG ; Jae Gu CHO
Korean Journal of Otolaryngology - Head and Neck Surgery 2015;58(12):886-889
Cystadenoma rarely arises in the parotid gland. It grows slowly without pain. Histopathologically, it is subdivided into papillary cystadenoma and mucinous cystadenoma. Mucinous cystadenoma arising from the salivary gland is a very rare benign tumor. A 25-year-old female patient visited our hospital with a left infra-auricular mass. Computed tomography scan showed a 3.1x2.3 cm size heterogeneous lesion with an irregular margin in the left parotid gland. Sono guided gun biopsy was performed to reveal fibrous tissue with atypical epithelial cell with mucin. Suspecting mucoepidermoid carcinoma, partial parotidectomy was performed for treatment and diagnosis. Histopathologic exam revealed mucinous cystadenoma. Cystadenoma of salivary gland has no distinct clinical feature, and is difficult to differentiate clinically from other salivary gland tumors as well as its malignancy. Thus, the possibility of malignancy must be considered for differential diagnosis.
Adult
;
Biopsy
;
Carcinoma, Mucoepidermoid*
;
Cystadenoma
;
Cystadenoma, Mucinous*
;
Cystadenoma, Papillary
;
Diagnosis
;
Diagnosis, Differential
;
Epithelial Cells
;
Female
;
Humans
;
Mucins*
;
Parotid Gland*
;
Salivary Glands
5.Cystadenoma of the Rete Ovarii.
Eungseok LEE ; Dae Su KIM ; Insun KIM
Korean Journal of Pathology 2001;35(6):555-557
The rete ovarii is a rare site for tumor development. We present a case of cystadenoma originating from the rete ovarii of a 58-year-old woman. It was a unilocular cyst of 7.0 cm in size, lined by flat, cuboidal, or columnar epithelial cells supported by fibromuscular tissue. Papillary growth and crevice formation of the inner surface were characteristic. The presence of a normal rete ovarii was helpful in correct diagnosis.
Cystadenoma*
;
Diagnosis
;
Epithelial Cells
;
Female
;
Humans
;
Middle Aged
6.The Limitations of Endoscopic Ultrasound-Guided Fine Needle Aspiration Cytology in the Diagnosis of Pancreatic Serous Cystadenoma: A Brief Case Report.
Heae Surng PARK ; Sun Och YOON ; Beom Jin LIM ; Joo Hee KIM ; Soon Won HONG
Korean Journal of Pathology 2014;48(5):405-408
No abstract available.
Cystadenoma, Serous*
;
Diagnosis*
;
Endoscopic Ultrasound-Guided Fine Needle Aspiration*
7.A Case of Simple Hepatic Cyst Complicated by Intracystic Hemorrhage.
Youn Hee MOON ; Sun Keun CHOI ; Yoon Seok HUR ; Keon Young LEE ; Sei Joong KIM ; Young Up CHO ; Seung Ik AHN ; Kee Chun HONG ; Seok Hwan SHIN ; Kyung Rae KIM ; Ze Hong WOO ; June Me KIM
Korean Journal of Hepato-Biliary-Pancreatic Surgery 2006;10(2):34-37
Simple liver cysts are common and benign lesions, and most of them are detected by ultrasonography (US) or computed tomography (CT) during a medical checkup. Because simple liver cysts are generally asymptomatic, they do not require treatment, although hemorrhage, infection or rupture may occur in rare cases and these cases must receive proper treatment. The diagnosis of simple liver cysts is usually easy because of their typical morphological findings on US or CT. However, when a liver cyst contains hemorrhage or it is inflamed on imaging studies, it is sometimes difficult to differentiate simple hepatic cysts from such conditions as cystadenoma and cystadenocarcinoma. In this report, we describe a case of simple liver cyst that was complicated by intracystic hemorrhage, and this malady was initially diagnosed as biliary cystadenocarcinoma. We successfully treated this lesion by left lateral segmentectomy.
Cystadenocarcinoma
;
Cystadenoma
;
Diagnosis
;
Hemorrhage*
;
Liver
;
Mastectomy, Segmental
;
Rupture
;
Ultrasonography
8.A Serous Papillary Cystadenoma of Borderline Malignancy in Testis.
Hyun Jun PARK ; Sung Woo PARK ; Won Hee CHON ; Suk Gun JUNG ; Nam Cheol PARK
Korean Journal of Andrology 2007;25(1):36-38
Serous papillary cystadenomas arising in testis have been rarely reported, and they often resemble ovarian serous tumors of borderline malignancy. Herein, we report a case of a serous papillary cystadenoma of the testis in a 59 year old man. Based on a clinical diagnosis of left testicular tumor, a left radical orchiectomy was performed. The pathologic evaluation revealed a serous papillary cystadenoma of borderline malignancy in the testis.
Cystadenoma, Papillary*
;
Diagnosis
;
Humans
;
Middle Aged
;
Orchiectomy
;
Testis*
9.A Case of Huge Ovarian Tumor.
Korean Journal of Gynecologic Oncology and Colposcopy 1995;6(3):214-217
We experienced a huge ovarian tumor of 16kg, measured 29 x 25 x 30cm in 85 years old woman. Pathologic diagnosis was mucinous cystadenoma, borderline malignancy of right ovary. We present this case with brief review of literatures.
Aged, 80 and over
;
Cystadenoma, Mucinous
;
Diagnosis
;
Female
;
Humans
;
Ovary
10.A Case of Huge Ovarian Tumor.
Korean Journal of Gynecologic Oncology and Colposcopy 1995;6(3):214-217
We experienced a huge ovarian tumor of 16kg, measured 29 x 25 x 30cm in 85 years old woman. Pathologic diagnosis was mucinous cystadenoma, borderline malignancy of right ovary. We present this case with brief review of literatures.
Aged, 80 and over
;
Cystadenoma, Mucinous
;
Diagnosis
;
Female
;
Humans
;
Ovary