1.Relationship between eye expression recognition and social functioning in patients with schizophrenia
Geng CHENG ; Yi DONG ; Kai WANG ; Cunyan ZHU ; Xiaoming LI ; Wenfei LI ; Xinyu CHEN ; Lida YANG ; Zulun XIONG ; Feng GENG ; Fengfeng ZHANG
Chinese Journal of Behavioral Medicine and Brain Science 2010;19(2):124-126
Objective To compare eye expression recognition in stable outpatients with schizophrenia with that in normal controls and to explore the relationships between eye expression recognition and social functioning.Methods 107 schizophrenic outpatients and 66 normal controls matched in age,sex and years of education were assessed with Eye Basic Emotion Discrimination Task(EBEDT) and Eye Complex Emotion Discrimination Task(ECEDT).The patients were also assessed with Social Disability Screening Schedule (SDSS).Results The correct numbers were significantly lower for patients to identify basic emotions of eye expressions(13.2±3.8 vs16.0±2.6,P<0.01) and complex emotions of eye expressions(17.9±4.3 vs 20.6±3.5,P<0.01)than those for controls respectively;the correct numbers to identify anger(3.1±1.0 vs.2.1±1.2,P<0.01),fear(1.8±1.0 vs 1.3±1.0,P<0.01) and disgust(1.8±1.1 vs 1.4±1.2,P<0.05)for controls were higher than those for patients significantly.The correct numbers to identify total basic emotions(r=-0.335,P<0.05)and total complex emotions (r=-0.374,P<0.05)in eye expressions showed negatively correlated with the total scores of SDSS in the patients after controlling age and total score of PANSS.Conclusions The ability to recognize basic and complicated emotions in eye expressions in the outpatients with schizophrenia is lower than that in the controls. It shows positively correlated with social functioning moderately in the patients.
2.The value of new 16S rRNA gene chip in pathogen detection of neonatal sepsis
Xiaoyan HU ; Songzhou XU ; Yuliang WU ; Kezheng LI ; Cunyan WANG ; Yuxin ZHOU
Chinese Journal of Neonatology 2018;33(5):325-328
Objective To study the value of new 16S rRNA gene chip in pathogen detection of neonatal sepsis.Method Newborns with suspected sepsis hospitalized in Peking University Shenzhen Hospital from January 2015 to December 2017 were chosen as the subjects.Blood culture and gene chip were both used to detect the pathogens of these infants.The positive rate,the detection time,and the blood volume needed for detection were compared between the two methods.Result A total of 306 cases of suspected neonatal sepsis were included in the study.Among them,34 (11.1%) were positive for blood culture and 54 (17.6%) were positive for gene chip.98 cases were diagnosed as neonatal sepsis,34 (34.7%) were positive for blood culture,and 52 (53.1%) were positive for gene chip.The positive rate of gene chip was higher than that of blood culture (P < 0.05).For the 5 common pathogens of neonatal sepsis,the positive rate of gene chip was higher than that of blood culture.Time to positivity (TTP) and pathogen identification time of blood culture were (14.6 ± 5.5) h and (72.9 ± 19.0) h,respectively.TTP and pathogen identification time of gene chip were both 3 h.The detection time of gene chip was significantly less than that of blood culture (P < 0.001).The blood volume needed for detection of blood culture and gene chip was 1 ~ 2 ml and 0.5 ml.Gene chip needs less blood volume than blood culture.Conclusion Compared with the traditional blood culture,gene chip can quickly detect the pathogens in the blood with higher positive rate and less blood volume.Gene chip is of great value in the diagnosis of neonatal sepsis.