1.Progress of research on apoptosis of breast cancer cells
Journal of Integrative Medicine 2003;1(3):226-9
This article reviewed information related to the apoptosis of breast cancer cells. Breast cancer is a common malignant tumor in women. Apoptosis is related to the response and resistance to treatment in breast cancer. Here we summarized and integrated the data on apoptosis and its role in the development, prognosis, and treatment of breast cancer. Further study on apoptosis in breast cancer can help find more candidates for predictors and indices of response. Such study will also develop treatment regimens that are tailored to individual tumors and thereby maximize survival.
2.A Study in Effect of Artemisinin and its Derivatives on Reversion of Multi-drug Resistance of Tumors
Cuiyan LU ; Xinyi CHEN ; Binghua TANG
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(04):-
Objective Effect of artemisinin and its derivatives on multi-drug resistance of tumor cells. Method The inhibition of cell proliferation and RI (reversal index) were determined by MTT method. Results The inhibitory effect of dihydroartemisinin and artemisunate on the proliferation of tumor cell is stronger than that of artemisinin. Artemisinin could partly improve KBv200 cell sensitivity to VCR in different concentrations. Conclusion Artemisunate and dihydroartemisinin effectively inhibited the proliferation of KBv200. Artemisinin could partly improve KBv200 cells sensitivity to chemotherapy medicine.
3.The prevalence of burnout and active interventions of graduate students of clinical medicine during residency training
Qun LU ; Yi XU ; Jianliu WANG ; Huan SHEN ; Cuiyan ZHANG
Chinese Journal of Medical Education Research 2016;15(1):17-20
The research data at home and abroad show that the overall burnout rate of clinical professional graduate students was high. They are vulnerable to burnout because of long duty hours, learn-ing pressure, intense and overloading work and especially the significantly reduced personal accomplish-ment in the situation of the contradiction between doctors and patients in our country. Burnout not only re-sults in psychological distress and physical symptoms, but also has negative effect on the quality of graduate medical education during residency training. Therefore, educators need to develop an active awareness of burnout and ought to perform interventions such as formulating the appropriate learning goals, improving the work efficiency, reducing work hours, positive psychological counseling and stress management training to prevent such occurrences.
4.Imaging of Anal Fistulas: Comparison of Computed Tomographic Fistulography and Magnetic Resonance Imaging.
Changhu LIANG ; Yongchao LU ; Bin ZHAO ; Yinglin DU ; Cuiyan WANG ; Wanli JIANG
Korean Journal of Radiology 2014;15(6):712-723
The primary importance of magnetic resonance (MR) imaging in evaluating anal fistulas lies in its ability to demonstrate hidden areas of sepsis and secondary extensions in patients with fistula in ano. MR imaging is relatively expensive, so there are many healthcare systems worldwide where access to MR imaging remains restricted. Until recently, computed tomography (CT) has played a limited role in imaging fistula in ano, largely owing to its poor resolution of soft tissue. In this article, the different imaging features of the CT and MRI are compared to demonstrate the relative accuracy of CT fistulography for the preoperative assessment of fistula in ano. CT fistulography and MR imaging have their own advantages for preoperative evaluation of perianal fistula, and can be applied to complement one another when necessary.
Adult
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Anal Canal/anatomy & histology
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Female
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Humans
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*Magnetic Resonance Imaging
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Male
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Middle Aged
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Rectal Fistula/diagnosis/*radiography/surgery
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Tomography, X-Ray Computed
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Young Adult
5.Comparing GWAS and Brain Structure-Specific Gene Expression Profiles Identifies Psychiatric Disorder-Related Brain Structures at Different Developmental Stages.
Xin QI ; Cuiyan WU ; Yanan DU ; Shiqiang CHENG ; Yan WEN ; Mei MA ; Chujun LIANG ; Li LIU ; Bolun CHENG ; Lu ZHANG ; Ping LI ; Feng ZHANG
Neuroscience Bulletin 2020;36(9):1046-1050