1.Retrospective Analysis on Turnover Ratio of Drug Stock in Our Hospital during 2010-2013
Hui LIU ; Cuixia GUO ; Aiguo SU
China Pharmacist 2014;(12):2156-2158,2159
Objective:To study the medicine storage management mode in our hospital. Methods: The medicine sales and inventory data were obtained from 2010 to 2013 by the HIS of our hospital. Medicine storage turnover ratio was calculated by using Microsoft Excel. The efficiency in the inventory management was evaluated by medicine storage turnover ratio. The storage control in our hospital was analyzed by the relevant references. Results: The medicine storage turnover ratio from 2010 to 2013 in our hospital was improved to 20. 06 times, the turnover days was reduced to 18 days which met the criteria for the review of the grade A class 3 hospital. Conclusion: The medicine storage management should be scientifically adjusted on the basis of the clinical characteristics and the use of medicines in the hospital. In this way, the improvement of medicine storage turnover ratio, the optimized control of the medicine stocks and the improvement of the social and economic benefit of the hospital will be realized.
2.Effect of intervention by follow-up on sexual quality of young and middle aged male patients with chronic heart failure
Cuixia ZHONG ; Jiali GUO ; Yuemin LIN
Modern Clinical Nursing 2014;(4):10-13
Objective To explore the effect of intervention by follow-up on sexual quality of young and middle aged male patients with chronic heart failure.Methods Seventy-eight patients with chronic heart failure in our hospital were enrolled into this study and randomly divided into the study group (n=40) and the control group (n=38).Psychological intervention during follow-up was carried out in the study group.The sexual quality of life after discharge for six month was investigated and evaluated with a retrospective questionnaire in two groups.Result Sexual quality of life in the study group was significantly improved compared to the control group (P<0.001).Conclusion Psychological intervention during follow-ups can increase sexual quality of life in young and middle aged male patients with chronic heart failure.
3.Ovarian Malignant Teratoma:Ultrasound Findings and Misdiagnosis Analysis
Cuixia GUO ; Longxia WANG ; Wei LIU ; Hong XU
Chinese Journal of Medical Imaging 2013;(10):775-779
Purpose To analyze the ultrasound manifestation of ovarian malignant teratoma, and to evaluate its diagnostic value and explore reasons for its misdiagnosis. Materials and Methods A retrospective study was conducted on the ultrasound findings of 25 patients with ovarian malignant teratoma confirmed surgically and pathologically (22 with immature teratoma, 3 with teratoma with malignant transformation). Their ultrasound imaging features were summarized and the reasons for misdiagnosis were further analyzed. Results The ultrasound imaging of 22 immature teratoma cases were divided into three types, namely, predominant solid components, predominant fluid components and mixed components of fluid and solid. All displayed calcification-like strong echo scattering in the low echo;color Doppler showed rich blood signal, little signal or no blood flow signal. Preoperative ultrasound presented1 case of immature teratoma (4.5%), 8 cases of ovarian tumors (malignant) (36.4%) and 13 cases of other diagnosis (59.1%). As to the 3 cases of teratoma with malignant transformation, the ultrasound imaging showed 2 cases were composed by fluid and solid components and that 1 case was mature cystic teratoma;typical hypoecho suggested malignant transformation. Preoperative ultrasound did not present teratoma with malignant transformation. Conclusion The ultrasound findings of ovarian malignant teratoma seem to be complicated and variable;thus the preoperative diagnosis rate is low though it still shows certain characteristics.
5.Changes in endothelial function in rats with subclinical hypothyroidism after levothyroxine treatment
Limin TIAN ; Tingting LI ; Cuixia GAO ; Jing LIU ; Qian GUO
Chinese Journal of Endocrinology and Metabolism 2015;31(4):360-362
Established rat models with subclinical hypothyroidism (SCH) were divided into three groups:subclinical hypothyroid(SCH),SCH treated with levothyroxine (L-T4),and control group.The L-T4 group displayed lowered total cholesterol and endothelin levels compared with the SCH group[(1.29 ±0.05 vs 2.38 ±0.55) mmol/L,(98.54 ± 32.43 vs 160.62 ±37.25) nmol/L,both P<0.05].Nitric oxide levels,left ventricular systolic pressure,and blood flow in abdominal aorta were significantly higher in the L-T4 group than those in the SCH group.The results of this study indicate that L-T4 treatment may improve endothclial dysfunction and hemodynamic changes in rats with SCH.
6.Safety of Ultrasound-guided Multifetal Pregnancy Reduction in the Second Trimester
Chen LI ; Longxia WANG ; Pingping WANG ; Cuixia GUO
Chinese Journal of Medical Imaging 2015;(3):222-225
PurposeTo evaluate the safety and feasibility of transabdominal ultrasound guided multifetal pregnancy reduction performed in the second trimester.Materials and Methods Forty-three women receiving embryo implantation were divided into two groups according to whether they have received multifetal pregnancy reduction including 16 in the reduction group in the second trimester to reduce multiple fetuses to twins, and 27 with twin pregnancy and no reduction. The pregnancy outcome was compared.Results In the reduction group, 1 patient had miscarriage because of intrauterine infection; 1 patient lost one of the retained fetuses in two days after reduction and delivered the remaining fetus. In the other 14 cases, 8 delivered and 6 were still in pregnancy. This group had 17 newborns, all without neonatal death or birth defects. In the non-reduction group, there was 1 spontaneous abortion. In 2 patients, 1 of the twin embryos stopped development. 1 case had a spontaneous abortion, the other 24 cases delivered uneventfully. There were 50 newborns in this group with 3 birth defects and no neonatal death. There was no statistically significant difference in gestational age at delivery, birth weight, and the incidence of maternal and neonate complications (P>0.05).Conclusion Multifetal reduction improves pregnancy outcomes, similar to non-reduction twin pregnancy. It is safe and feasible to perform multifetal pregnancy reduction in the second trimester.
7.Relationship of TSH with atherosclerosis-related factors in subclinical hypothyroidism
Limin TIAN ; Bin YANG ; Cuixia GAO ; Jing LIU ; Qian GUO
Chinese Journal of Endocrinology and Metabolism 2015;(2):133-135
Two hundred and fifty patients with subclinical hypothyroidism ( SCH) and 120 euthyroid volunteers were recruited for the study, SCH patients were stratified into 2 groups according to TSH levels(group A:TSH<10 mIU/ L; group B: TSH>10 mIU/ L). All subjects were examined for clinical characteristics, thyroid profile, lipid profile, and biomarkers of early atherosclerosis. Patients in group B received L-thyroxine replacement treatment to achieve euthyroidism. After 6 months of stable euthyroidism all measurements were repeated. SCH patients had higher levels of total cholesterol(TC), low-density lipoprotein-cholesterol(LDL-C), asymmetric dimethyl arginine (ADMA), carotid artery intima media thickness(CIMT), thromboxane B2(TXB2), and C-reactive protein(CRP) but with lower nitric oxide(NO) level compared with euthyroid subjects. Levels of TC, LDL-C, CIMT, TXB2, and ADMA decreased, and NO level increased significantly after 6 months of euthyroidism. TSH was positively correlated with TC, LDL-C, CIMT, ADMA, and TXB2; and negatively correlated with NO. Based on multivariate regression analysis, TSH was an independent influential factor of CIMT and NO. We conclude that raised TSH is an important risk factor of atherosclerosis in SCH.
8.Application of ultrasound biomicroscopy on skin assessment in normal adults and psoriasis patients
Shuo, LI ; Xiaoning, LIANG ; Yan, ZHANG ; Cuixia, LIU ; Yali, HUANG ; Ruigang, LU ; Ruijun, GUO
Chinese Journal of Medical Ultrasound (Electronic Edition) 2015;(1):30-34
ObjectiveTo investigate the features of normal and psoriasis skin on ultrasound biomicroscopy (UBM) and explore the method of thickness measurement.MethodsUsing 50 MHz ultrasound probe of biological microscope, ultrasonographic observation and ultrasonic thickness measurement were conducted in 90 normal adults and 40 psoriasis patients. Innormal patients, ultrasound evaluations were performed at 10 different parts of the body skin.ResultsOn sonogram, the normal skin showed a “sandwich” structure with two parallel hyperechoic bands and the middle isoechoic dots and short liens. The sonograms of the psoriasis skin showed obviously thickened epidermis and dermis, disordered internal structure and clear boundary from adjacent normal skin. The range of the epidermis’ thickness measurement was between the medial forearm (0.12±0.03) mm and the palm (0.29±0.15) mm. The range of dermal thickness measurement was between the back hand (1.18±0.32) mm and parasternal (1.55±0.21) mm. Psoriasis skin was thicker than the uninvolved skin (P<0.001). And the dermis’ thickness of uninvolved skin in psoriasis patients was thicker than that of the normal adults (P<0.001).ConclusionNormal adult’s epidermis, dermis and skin appendages can be shown clearly using 50 MHz ultrasound biomicroscopy. And ultrasound biomicroscopy canaccurately measure the thickness of dermis and epidermis, which provides the basis for the diagnosis and treatment of psoriasis.
9.Clinical Observations on Warm Needling Moxibustion plus Julisanjie Bolus for the Treatment of Hysteromyoma
Shaoqiong GUO ; Xin LIN ; Cuixia YANG ; Weizhuang HE ; Yue ZHANG ; Weiming LI
Shanghai Journal of Acupuncture and Moxibustion 2016;35(4):437-439
Objective To use warm needling moxibustion plus Julisanjie Bolus for the treatment of hysteromyoma and explore a new way to treat hysteromyoma. Method A treatment group of 40 hysteromyoma patients received warm needling moxibustion plus Julisanjie Bolus; a conventional treatment group of 40 hysteromyoma patients, Julisanjie Bolus; a control group of 40 hysteromyoma patients, mifepristone. The therapeutic effects were compared between the treatment group and the conventional treatment or control group. Result The cure rate and the total efficacy rate were 12.5% and 97.5%, respectively, in the treatment group, 5.0% and 75.0%, respectively, in the conventional treatment group and 5.0% and 72.5%, respectively, in the control group. Conclusion The therapeutic effect was significantly better in the treatment group than in the conventional treatment and control groups (P<0.05). There were no obvious adverse reactions during the clinical trial of warm needling moxibustion plus Julisanjie Bolus for the treatment of hysteromyoma.
10.Analysis on the reasons of contrast agent reflux during transvaginal real-time three-dimensional hysterosalpingo-contrast sonography
Na LIANG ; Qingqing WU ; Jinghua LI ; Fengyun GAO ; Cuixia GUO ; Yuan TIAN
Chinese Journal of Ultrasonography 2015;(9):797-799
Objective To discuss the possible reasons of contrast agent reflux during transvaginal real-time three-dimensional hysterosalpingo-contrast sonography (TVS RT-3D-HyCoSy),and in order to provide scientific evidences for reducing the contrast agent reflux.Methods The sonographic features of contrast reflux were observed in the images of 167 infertile patients who underwent TVS RT-3D-HyCoSy, and the association of the incidence rate of the reflux with tubal patency,the types of infertility,endometrial thickness,menstrual clean days,abnormal uterine cavity,the history of intrauterine operations,pelvic operations and ectopic pregnancies were analyzed.Results The incidence rate of the reflux during TVS RT-3D-HyCoSy was 41 .3%.The incidence rates of reflux in unilateral patency and bilateral obstruction were 4.929 and 9.21 5 times of that of bilateral patency respectively.The incidence rate of reflux in the secondary infertility cases was significantly higher than that of primary ones(P <0.05).Logistic regression analysis demonstrated that the reflux is associated with the tubal patency,the endometrial thickness and the history of intrauterine operations,and none of the other factors.Conclusions TVS RT-3D-HyCoSy could differentiate the images of reflux better;the proper timing of the contrast examination and avoiding the damage of endometrium would reduce the incidence of the reflux.