Objective To explore the efficacy of self-designed waist pillow combined with plastic toilet in bedridden patients in emergency department.Methods From August 2013 to February 2014,90 bedridden patients in emergency department were divided into the observation group 1,the observation group 2 and the control group by random digits table with 30 cases in each group.Patients in the observation group 1 lied in the suprine position,and elevating head of bed 15 to 30 degrees,with pillow under the waist,and plastic toilet under the buttocks.Patients in the observation group 2 used the same method as that of the observation group 1,except that they did not use waist pillow.The control group lied in the suprine position,only used plastic toilet.The defecation and other related items were compared between the three groups.Results The observation group 1 was better than those of the observation group 2 and the control group in preventing pressure ulcers,urine leakage and backflow,comfort degree,worrying degree,defecation difficulty degree.Conclusions Application of waist pillow and plastic toilet in bedridden patients in emergency department could reduce the skin damage,and let patients defecate smoothly,which was in accordance with the connotation of comfort nursing.