1.Application of change speed of lithotomy position in the patients with gynecological laparoscopic surgery
Suzhen HUANG ; Lihua CHEN ; Cuiqin LIN ; Lichan XIE
Journal of Clinical Medicine in Practice 2017;21(6):142-144
Objective To explore the application of change speed of lithotomy position in the patients with gynecological laparoscopic surgery.Methods A total of 120 gynecological laparoscopic surgery patients in our hospital were randomly divided into observation group and control group,pneumoperitoneum pressure of two groups was 11 mmHg.The change speed of lithotomy position in the control group was in 6 s,the observation group was > 30 s,and the changes of hemodynamics and blood gas indexes were compared.Results SBP and DBP after pneumoperitoneum in the two groups were increased compared with that before pneumoperitoneum (P < 0.05).The increase of DBP and SBP after pneumoperitoneum in the observation group was less than that in the control group (P < 0.05).PETCO2 after pneumoperitoneum in the observation group showed no statistically significant compared with pneumoperitoneum before (P > 0.05),but the control group had higher PETCO2 than that before pneumoperitoneum,there were statistically significant differences (P < 0.05).The observation group and the control group had a tendency to rise in airway pressure after pneumoperitoneum,but no statistical significance between the two groups was found (P > 0.05).Conclusion Prolonging change time of lithotomy position can reduce the influence of hemodynamics for the patients with gynecological laparoscopic operation,and it is beneficial to the recovery of lung function.
2.Application of change speed of lithotomy position in the patients with gynecological laparoscopic surgery
Suzhen HUANG ; Lihua CHEN ; Cuiqin LIN ; Lichan XIE
Journal of Clinical Medicine in Practice 2017;21(6):142-144
Objective To explore the application of change speed of lithotomy position in the patients with gynecological laparoscopic surgery.Methods A total of 120 gynecological laparoscopic surgery patients in our hospital were randomly divided into observation group and control group,pneumoperitoneum pressure of two groups was 11 mmHg.The change speed of lithotomy position in the control group was in 6 s,the observation group was > 30 s,and the changes of hemodynamics and blood gas indexes were compared.Results SBP and DBP after pneumoperitoneum in the two groups were increased compared with that before pneumoperitoneum (P < 0.05).The increase of DBP and SBP after pneumoperitoneum in the observation group was less than that in the control group (P < 0.05).PETCO2 after pneumoperitoneum in the observation group showed no statistically significant compared with pneumoperitoneum before (P > 0.05),but the control group had higher PETCO2 than that before pneumoperitoneum,there were statistically significant differences (P < 0.05).The observation group and the control group had a tendency to rise in airway pressure after pneumoperitoneum,but no statistical significance between the two groups was found (P > 0.05).Conclusion Prolonging change time of lithotomy position can reduce the influence of hemodynamics for the patients with gynecological laparoscopic operation,and it is beneficial to the recovery of lung function.
3.Associations of serum low-density lipoprotein cholesterol with hematoma enlargement, early neurological deterioration, and outcome in patients with acute spontaneous intracerebral hemorrhage
Ting LAN ; Xiwa HAO ; Lin LYU ; Cuiqin ZHANG ; Hongmei QIAO ; Bobo ZHANG ; Yongming CHEN ; Qidi BO ; Meiyou YAN ; Hui LYU ; Jingfen ZHANG
International Journal of Cerebrovascular Diseases 2024;32(7):506-511
Objective:To investigate associations of serum low-density lipoprotein cholesterol (LDL-C) with hematoma enlargement, early neurological deterioration (END), and outcome in patients with acute spontaneous intracerebral hemorrhage (ICH).Methods:"A multi-center registration study for spontaneous intracerebral hemorrhage in Inner Mongolia" (registration number: ChiCTR2000029494) database was used to include patients with ICH who completed their first head CT scan within 6 hours after onset, underwent blood lipid examination, CT follow-up within 24 hours of onset, and accurately measured hematoma volume using 3D Slicer software between June 2020 and September 2022. HE was defined as hematoma volume increasing >33% or >6 ml at 24 hours, or ventricular hematoma volume increasing ≥1 ml compared to the baseline. END was defined as an increase of ≥4 in the National Institutes of Health Stroke Scale (NIHSS) score from the baseline or death within 24 hours after onset. The follow-up was conducted at 3 months after onset, and the modified Rankin Scale score >2 was defined as poor outcome. Multivariate logistic analysis was used to determine the independent correlation between LDL-C and HE, END, and outcome. Results:A total of 338 patients with ICH were enrolled, including 206 males (60.9%). LDL-C was 2.39±1.22 mmol/L. Eighty-eight patients (26.0%) developed HE, 67 (19.8%) developed END, and 162 (47.9%) had poor outcome at 3 months. Multivariate logistic analysis showed that after adjusting for confounding factors, there was a significant independent negative correlation between LDL-C and HE (odds ratio 0.312, 95% confidence interval 0.208-0.467; P<0.001) and END (odds ratio 0.408, 95% confidence interval 0.275-0.606; P<0.001), but not with the outcome at 3 months. Conclusion:Lower LDL-C is associated with HE and END in patients with ICH, but not with the outcome.