OBJECTIVE To analyze the impact of clinical application sheets for special antibiotics on clinical medication and the existing questions in implementation and irrational phenomena caused by the use of antibiotics.METHODS All the applications sheets for the first month clinical use of special antibiotics in our hospital were analyzed retrospectively,and their used dosage before and after of was compared monthly.RESULTS It was indicated that the partial application sheets were filled out incompletely;the dosage of special antibiotics after clinical application was declined obviously,while the pathogen test rate for the sample was too low and the starting point of the preventive use of antibiotics in some departments was too high.CONCLUSIONS The applications sheets for special antibiotics promote the rational usage of antibiotics in some extent;however,there is still deficiency in operation.Meanwhile,there are some problems in the clinical medication in our hospital and need to take the comprehensive preventive measures to manage it.

Objective To survey the 238U radioactivity level in the surface soil in the Beijing-Tianjin-Hebei Border (BTHB) region,and to prepare a high resolution distribution map of 238U activity concentrations.Methods The soil samples were collected in a grid (10 km × 10 km).The activity concentrations of 238U in soil samples were measured by using HPGe γ spectrometry.The distribution of the activity concentrations of 238U in soil samples was mapped by the aid of MAPGIS software.Results In total,416 samples were collected and measured.The activity concentrations of 238U were in the range of 0.1-106.0 Bq/kg,with an average of 34.7 Bq/kg.The 238U activity concentration distribution map showed that 238U activity concentration was in the range of 15-55 Bq/kg mostly on the surface soil in the BTHB region.Conclusions The map of 238U activity concentration shows the distribution of 238U activity concentration in the BTHB region.It is of importance to map the distribution of 238U activity concentration in the BTHB region,by converting a huge amount of data into the simple and intuitive graphics,and for evaluating the regional environmental radioactivity and studying the radioactive substance migration within the locality.

Objective To investigate the effect of informational support on disease uncertainty in liver cancer patients undergoing interventional therapy. Methods Sixty patients of liver cancer patients undergoing interventional therapy were randomly divided into the intervention group and the control group with 30 in each.The control group was treated with general treatment and care. The patients in the intervention group were given general treatment and care with a series of informational support interventions. Patients in the two groups were measured by uncertainty in illness scale (MUIS) at the day of admission,before operations and discharged from hospital. The measurement results were statistically analyzed. Results There was significant decrease about disease uncertainty scores both on the day before operation and the day before discharge in the intervention group compared to the day of admission. The decreasing score of uncertainty in illness in the intervention group was significantly greater than the control group on the day before operation and the day before discharge. Conclusions A series of informational support interventions could significantly reduce the diseases uncertainty in liver cancer patients undergoing interventional therapy.

Objective To develop the software for the assessment of radionuclide concentration and doses from atmospheric dispersion. Methods Based on procedures for radionuclide atmospheric dispersion and dose assessment in IAEA publications (safety series reports No. 19), a parameter database was constructed using Microsoft Access, and the dispersion model and dose assessment methods were computerized using Microsoft Visual Basic 6.0, then we got the dose assessment software for radionuclide atmospheric dispersion. Results Atmospheric radionuclide concentration and public effective dose in a year could be estimated rapidly with the present software. Conclusion The present software provides a practical and rapid tool for evaluation and assessment the influence of radionuclide atmospheric dispersion, which can be used in the evaluation of atmospheric radionuclide concentration in routine monitoring or nuclides/radiological emergency, and also can be used as the screening evaluation in environmental surveillance.

Humans ; Neurilemmoma ; Paranasal Sinus Neoplasms ; Paranasal Sinuses ; pathology

Objective To develop a radionuclide parameter database on internal contamination in nuclear emergencies. Methods By researching the radionuclides composition discharged from different nuclear emergencies, the radionuclide parameters were achieved on physical decay, absorption and metabolism in the body from ICRP publications and some other publications. The database on internal contamination for nuclear incidents was developed by using MS Visual Studio 2005 C# and MS Access programming language. Results The radionuclide parameter database on internal contamination in nuclear emergency was established. Conclusions The database may be very convenient for searching radionuclides and radionuclide parameter data discharged from different nuclear emergencies, which wonld be helpful to the monitoring and assessment of internal contamination in nuclear emergencies.

BACKGROUND:The key of vertebroplasty and percutaneous kyphoplasty to success is whether the puncture needle can accurately reach the vertebral body through pedicle. Therefore, it is important to identify the correct point and direction of needling in the X-ray fluoroscopy. Among many methods published in present reports, the puncture point and the puncture angle are not fixed. Few reports concerned whether the puncture needle perforated pedicle medial wal . OBJECTIVE:To seek safe, effective puncture point and the puncture angle of percutaneous pedicle from the perspective of anatomy and radiography. METHODS:The best entry point during percutaneous vertebroplasty in the X-ray fluoroscopy:dissection was performed on thoracic, lumbar skeletal samples (T 6-L 5 ) to find the position of pedicle axis leading to the rear of the vertebral body, and this position is the best entry point of percutaneous vertebroplasty. It was fixed with mini-screw. The relationship of the best entry point and pedicle developing position in the X-ray fluoroscopy was analyzed to find the best entry point in the X-ray fluoroscopy. The best entry angle during percutaneous vertebroplasty:The average included angle of pedicle axis and vertebral sagittal line was measured using autopsy and CT scanning on adult thoracic and lumbar skeletal samples (T 6-L 5 ). The best entry angle during percutaneous vertebroplasty was found. RESULTS AND CONCLUSION:During percutaneous vertebroplasty, the best entry point in the X-ray fluoroscopy was the left pedicle projection 9 area and right pedicle projection 3 area. The optimal needle angle during percutaneous vertebroplasty:5°-10° in lumbar vertebra L1-L4;20° in L5, not more than 25°;about 5° in thoracic vertebra T6-T12 .

Objective To assess the accuracy and precision of γ-spectrometry analysis, and to obtain accurate and valid measurement results in the middle term and long term. Methods A nationwide intercomparison on gamma-ray spectrometry measurement of activity concentration of 226Ra, 232Th and 40K in soil and building material was organized by National Institute for Radiological Protection( NIRP) , China CDC. Results 15 laboratories participated in this intercomparison, with 13 laboratories produced acceptable results. Only 2 laboratories were classified as " not acceptable" , including one for inappropriate accuracy in determination of 40K and another for inappropriate precision determination of 226Ra in both kinds of the samples. Through comment and discussion, the second round intercomparison got satisfactory results. Conclusions The overall measurement results of samples for intercomparison are in close agreement with the reference values. Most of the laboratories involved in the intercomparison have good ability in γ-spectrometry analysis.

Objective To describe a simplified generic procedure to evaluate the external exposure dose evaluation in radiological emergency, and to compile the corresponding computer software. Methods Based on the related reports of IAEA, this generic procedure of external exposure dose evaluation in radiological emergency was compiled to computer software by Visual Basic 6.0. Results The generic procedure for evaluation of external exposure dose could be used in the external exposure radiation accident emergency. The actual accident data were input in this software, then the results from this software agreed with those of the actual accident well. The maximum error was 40% , and the minimum error was 6%.Conclusions The generic procedure for evaluation of external exposure dose could provide practical emergency response guidance. The software might help to evaluate the accidental dose more quickly and accurately, and provide scientific basis to take the immediate response actions.

Objective To explore the electrophysiological examination results and risk factors of type 2 diabetic peripheral neuropathy. Methods 337 patients with type 2 diabetes from August 2014 to December 2016 in the first people's hospital in Shizuishan city were divided into DPN group (n=218) and NPDN group(n=119) according to the results of NCV and SSR examinations. The general information and laboratory biochemical indicators in the two groups were compared. Multivariate Logistic regression was used to analyze the risk factors of DPN. Results The diagnosis rate of DPN detected by NCV combined with SSR was higher than that of NCV or SSR alone(P<0.05);There were significant differences in age,duration of diabetes,history of hypertension,systolic blood pressure,2h FBG,HbA1c,FINS,2 h INS,FC-P, 2h FC-P,ACR between the DPN group and NPDN group(P<0.05);Logistic multivariable analysis showed that age, duration of diabetes, 2h FBG, HbA1c, ACR were independent risk factors for DPN. Conclusion It is beneficial to increase the diagnosis rate of DPN by NCV combined with SSR. There is a higher incidence rate of DPN type 2 diabetes patients with older grade, longer duration of diabetes, higher 2h FBG, HbA1c and ACR.