OBJECTIVEThis study aimed to investigate the osseointegration condition by measuring the implant stability quotient (ISQ) to study the effect of osseointegration in the posterior area by Shenggu pills.

METHODSA total of 101 DENTIUM implants were placed in 48 patients. Fifty implants placed in 24 patients were addressed as usual, whereas 51 implants placed in 24 patients were treated with Shenggu pills. ISQ was tested on the day of surgery and consecutively at 4, 8, and 12 weeks. All data were analyzed.

RESULTSThe efficacy of the treatment group was no much better than that of control group on the day of surgery and consecutively at 12 weeks with no significant difference (P>0.05). The efficacy of the treatment group was significantly better than that of the control group at 4 and 8 weeks (P<0.05). The implants placed in the mandible were significantly better than those placed in the maxilla (P<0.05).

CONCLUSIONSEarly intake of Shenggu pills could accelerate the implant bone union, improve the implants' ISQ, and ensure the success rate of the operation.

We reported one case of a patient with Sjögren's syndrome and dental implant. This patient was followed up for more than one year. The patient was diagnosed with Sjögren's syndrome for 5 years and treated with long-term corticosteroid. Four implant-tissue interface hydrophilic implants were placed on 15, 16, 44, and 46 of the mandibular and maxillary areas. After the surgery was completed, the patient was treated with oral antibiotic and "shenggu pills" to prevent infection and glucocorticoid to manage Sjögren's syndrome. Consequently, six implants were placed in other parts of the mandibular and maxillary areas. After more than one year of follow-up, the implants and prosthesis remained stable and had no complications. Cone beam CT reconstruction showed good implant-bone combination.
Dental Implantation ; Dental Implants ; Follow-Up Studies ; Humans ; Mandible ; Maxilla ; Sjogren's Syndrome

Osseointegration plays an important role in the functions and aesthetics of dental implant. This paper focus on the hormones closely related to the bone metabolism, including glucocorticoid, parathyroid hormone, calcitonin, melatonin, and oestrogen, and reviews the influence of hormones on the osseointegration.