Objective:To analyze and evaluate the uncertainty of spectrophotometer detection device, stability, repeat-ability, the accuracy of the standard testing devices for the detection of spectrophotometer in laboratory.Methods: To calculate the uncertainty of measurement of standard gear, stability, repeat ability for evaluating the accuracy of the standard device.Results: According to the national standard, through analysis and calculation, the veracity and reliability of standard device were proved.Conclusion: Through analysis and evaluation, the uncertainty of verification device of spectrophotometer met the requirement of value. The repeatability and stability complied with the requirement of standard establishment. It can use in detection spectrophotometer, and make sure the results accurate and reliable.

Objective: The system of quality control management of medical equipment is an important management means to maintain medical security, achieve quality control management by the information technology, and it can quickly improve the efficiency of management and increase the effectiveness of the management. Methods: Using the tools of B/S of three layer architecture technology, the management of medical device adverse event, assessment of medical equipment, management of medical equipment scrap, management of medical metrology certificate, and other functions are developed. Results:The adverse events, examine, scrap, certificate management, and other functions are designed through the software, the quality of the equipment is mastered in time through different testing cycle of data comparison, so that the related departments can take preventive maintenance to make the equipment in good state. Conclusion: The informational system of quality control management is used to promote the modernization of medical management and guarantee effectively the quality and safety of medical equipment.

Objective:According the review of three grade hospital, it is analysis the problems that evaluation experts pointed out. We can take effective measures and improve insufficient of control management to increase management efficiency. Methods: We can perfect quality control management system, improve the assessment mechanism, establishment of information management system to strengthen the quality control management of medical equipment. Results:After implementation of improvement measures, improve the management mechanism, the quality control management come into the information, scientific management stage. Conclusion:Through the review, we can promote construction by evaluation;the quality control and management work are improved. We can ensure the quality and safety of medical equipment, which can give full play to efficiency, better services for patients.

Objective:To design the medical equipment quality control management system and it can improve the efficiency of management, and provide data of quality evaluation of equipment for purchasing.Methods: Quality control management system adopts three layer architecture technology of B/S and publishing tools of IIS, it can implement the various functions of quality control in the management.Results: The system realized some function, like data entry, modify, query and extracting features, et al. The system can evaluate the performance of the equipment through the data analysis. So the maintenance department can preventive maintenance through the data. The equipment is insured in good condition, the purchasing department choose stability equipment in clinical. Conclusion: Quality control management system can evaluate the quality of the medical equipment through the testing data, at the same time the system can intuitive understanding controlled state of the medical equipment for managers, the mangers can take the effective measures to ensure the safety of the medical equipment quality through the system.

Objective To investigate the incidence and structure of mental disability in children with movement disorders. Methods 157 children with movement disorders (103 with cerebral palsy and 54 with mental retardation) were assessed with Gesell developmental schedules,and mental disability was identified as development quotient (DQ)<75. Results The incidence of intelligence disability was 92.2% in children with cerebral palsy, including 91.2% in spastic type, and 100% in dyskinetic, mixed or dystonic type. The development of gross motor was retarded in children with spastic cerebral palsy, and gross and fine motor in children with dyskinetic cerebral palsy, compared with those with mental retardation. Conclusion It is important to focus the mental development in children with movement disorders, especially the dyskinetic cerebral palsy. Gesell developmental schedules should be used carefully to assess the mental development in children with movement disorder.

Objective To determine the levels of insulin-like growth factor binding protein-2 (IGFBP-2) in glioma tumor tissue and their clinical significance. Methods The levels of IGFBP-2 in glioma samples from 45 patients were detected with immunohistochemistry. Their correlation with tumor grade, p53 and Ki67 expression levels and the outcome of patients were tested. Results IGFBP-2 increased in glioma tissue in a grade-dependent manner, and significantly correlated with p53 and Ki67 expression. High IGFBP-2 level is significantly associated with earlier tumor recurrence and shorter overall survival. Conclusion Tumor IGFBP-2 levels can supply more prognostic information to the tumor grading system.

Animals ; Carcinoma, Squamous Cell ; genetics ; Colorectal Neoplasms ; genetics ; metabolism ; Enzyme Activation ; Esophageal Neoplasms ; genetics ; Genome-Wide Association Study ; Head and Neck Neoplasms ; genetics ; Humans ; Neoplasms ; chemically induced ; enzymology ; genetics ; Phosphoinositide Phospholipase C ; chemistry ; genetics ; metabolism ; physiology ; Signal Transduction ; Skin Neoplasms ; chemically induced ; enzymology ; Stomach Neoplasms ; genetics ; Urinary Bladder Neoplasms ; metabolism ; pathology ; ras Proteins ; metabolism

With the rapid development of healthcare technologies, the improvement of patient health expecta-tions, and the increasing of the government or insurer's financial budget pressure, risk-sharing agreements has be-come the focus of the governments or insurer concerned. This article systematically analyzed Australia, New Zealand, Taiwan risk-sharing agreements from five aspects, including the operation main, scope, classification, application processes and the implementation effects. According to the results of the analysis, we suggests that China should im-prove risk-sharing agreements theoretical basis, diversify risk-sharing agreements models, establish risk-sharing a-greements standardization process and so on.

Objective By analyzing the monitoring data and the outbreak of brucellosis in Qingyang City in 2014,to provide a epidemiological evidence for prevention and control of the disease.Methods According to the requirements of Gansu Province Human Brucellosis Surveillance Program and Qingyang City Human Brucellosis Surveillance Program,we implemented epidemiological investigation in the high-risk group of brucellosis in 40townships under the jurisdiction of 8 countries in Qingyang.Detailed information on subject's exposure with livestock,clinical symnptoms and incidence were asked and recorded.Venous blood samples of 3-5 ml of suspected cases were collected.Then the rose bengal plate agglutination test (RBPT) was used to test the separated serum,and the standard tube agglutination test (SAT) was used to test the serum sample of positively infected person in the laboratory.Our test methods and results were in accordance with the implementation of Criteria for the Diagnosis of Brucellosis(WS 269-2007).For identified outbreaks,appropriate actions were taken based on regulations in the Brucellosis Prevention Manual.Results In 2014,we inspected 9 498 people in the whole city,implemented epidemiological investigation and collected 1 673 blood samples.Three hundred and thirty-eight samples were positive for RBPT.The infection rate was 20.20％ (338/1 673).Also there were 260 SAT positive samples (1 ∶ 100 ++above).The positive rate was 15.54％ (260/1 673).Combined with clinical symptoms,260 cases were confirmed (241cases were newly made and 19 cases were primary).The prevalence rate was 2.74％ (260/9 498).There were 12cases in total in outbreak points (2 cases in Huachi,3 cases in Huanxian,5 cases in Heshui,1 case in Qingcheng,and 1 case in Zhenyuan).Our epidemiological survey included 1 270 people,and we collected 308 blood samples.Fifty-one presented positive results for RBPT.The positive rate was 16.51％ (51/308);50 presented positive results for SAT.The positive rate was 16.23％ (50/308).Fifty cases were confirmed cases in the outbreak,all of which were new cases of this year,and the incidence was 3.94％ (50/1 270).Conclusions Brucellosis epidemic in Qingyang City has begun to rebound obviously,at the same time the outbreak points increased significantly.Both of which should capture the authorities' attention.The local government is supposed to undertake the due obligations to strengthen prevention and make efforts to control the spread of brucellosis.

Objective: To investigate the influence of Icarrin(ICA) on transforming growth factor ?2(TGF?2) expression by PG cells and the mechanisms of reversion of TGF?2 mediated immunosuppression by ICA.Methods: Cell proliferation and cytotoxici- ty were assayed by MTT assay. mRNA level of TGF?2 and perforin was detected by RT-PCR assay. assay.Expression of TGF?2 and IL- 2R? was analysed by folw cytometry assay. Results: ICA could inhibit the protein and mRNA expression of TGF?2 in PG cells. It could also reverse the supressed cytotoxicity of LAK, CD3AK cells by TGF?2. The IL-2R? expression on LAK and perforin gene transcription and proliferation of CD3AK inhibited by TGF?2 were also partly recovered. Conclusion: The anti-anti-tumor activity of ICA is at least partly due to its capability of inhibiting TGF?2 expression in tumor cells and restoring the cytotoxicity of immunocompetent cells inhibited by TGF?2.