1.Effects of acute hypervolemic hemodilution with HES130/0.4 and HES200/0.5 on blood coagulation
Chinese Journal of Anesthesiology 2008;28(3):242-245
Objective To evaluate the effects of 6% hydroxyethyl starch (HES)130/0.4 and 6% HES 200/0.5 on blood coagulation in patients undergoing major operation under general anesthesia.Methods Sixty ASA Ⅰ or Ⅱ patients aged 18-64 yr undergoing major operation under general anesthesia during which the blood loss was expected to be>20%of blood volume were allocated randomly into 3 groups(n=20 each):Ⅰ control group(C);Ⅱ6% HES200/0.5 group (H) and Ⅲ HES130/0.4 group (V).In group H and V the patients Arterial blood samples were taken before(T1),immediately(T2)and 1 h after the end of fluid infusion(T3)for determination of hematocrit(Hct),platelet count(PLT)and prothrombin time(PT),platelet maximum aggregation test induced by 5 μmol/L ADP,and Sonoclot coagulation and platelet function analysis(gbACT,CR,PF,TP).Activated partial thromboplastin time(Am),coagulation factor Ⅷ (FⅧ)activity and von Willebrand factor(vWF)were measured only in group H and V.Results (1) PT and APTT were significantly prolonged after fluid infusion at T2 and T3 as compared with the baseline values at T1 in group H and V.(2)FⅧ activity and platelet maximum aggregation induced by ADP were significantly decreased at the end of fluid infusion at T2 as compared with the baseline at T1 but increased again at T3 in group H and V.(3)There was no significant change in Sonoclot coagulation parameters after fluid infusion as compared with the baseline except clot formation rate (CR)in group H and V.Conclusion Acute hypervolemic hemodilution with 6% HES130/0.4 or 200/0.5 has minimal effect on blood coagulation and there is no significant difference in blood coagulation changes induced by 6%HES130/0.4 and 200/0.5.
2.Investigation on Indoor Air Pollution in Newly Decorated Houses in Jiaozuo City
Journal of Environment and Health 2007;0(09):-
Objective To know the indoor air pollution status in the newly decorated residential houses in Jiaozuo and to study the effect of decoration materials on the pollution. Methods To monitor formaldehyde, ammonia and benzene levels in the indoor air of 39 newly decorated rooms in Jiaozuo. Results The exceed standard rates of formaldehyde, ammonia and benzene in the indoor air were 73.6%, 84.7% and 25.8% respectively. Exceed standard rate of formaldehyde in the room which held the new furniture was the highest, 88.8%. Conclusion Decoration may cause indoor air pollution, the most part of the pollutants are formaldehyde and benzene. The level of the pollution depends on the different usages of the rooms.
3.Comparison of the clip displacement in the operation cavity during external-beam partial breast irradiation depicted by kV-plain film and cone-beam CT under active breathing control assisted with moderate deep inspiration breath hold..
Cui-cui LIU ; Jian-bin LI ; Jin-ming YU
Chinese Journal of Oncology 2009;31(12):921-922
4.T_1 and T_2 lymphocyte subset alterations in patients with colorectal cancer
Ming CUI ; Shan WANG ; Yingjiang YE ; Zhirong CUI ; Yang KE
Chinese Journal of General Surgery 2001;0(07):-
Objective The purpose of this study was to analyze the alterations of T_1、T_2 lymphocyte subsets in the peripheral blood of patients with colorectal cancer. MethodsTwenty patients with primary colorectal cancer were enrolled into this study, T_1 and T_2 in the peripheral blood were evaluated by detecting the intracellular interferon-? and interleukin-4 production with 4-color flow cytometry. ResultsThe percentage of T_1 and T_2 in the peripheral blood of cancer patients was lower significantly than healthy controls [(36?11)% and 3.3(1.9)% vs. (46?12)% and 4.1(3.1)%](P
6.Research progress of establishing cardiomyocytedisease models by human induced pluripotent stem cells
Ning CUI ; Lei LI ; Ming CUI ; Feng LAN
Basic & Clinical Medicine 2017;37(9):1331-1335
Induced pluripotent stem cell is a landmark in the stem cell study field, which has rapidly developed in the past 10 years.By obtaining induced pluripotent stem cells from somatic cell, and then differentiating into cardiomyocyte, various cardiomyocyte disease models could be established,which can be used for research of disease mechanisms, drug screening and gene therapy.This review introduces the successfully established cardiomyocyte disease models from human induced pluripotent stem cells, and points out the problems and prospects.
7.Influence of tumor burden on T1 and T2 lymphocyte subsets in patients with gastrointestinal cancers.
Ming CUI ; Shan WANG ; Ying-jiang YE
Chinese Journal of Oncology 2006;28(5):371-372
Adult
;
Aged
;
Colectomy
;
Colonic Neoplasms
;
pathology
;
surgery
;
Female
;
Gastrectomy
;
Humans
;
Male
;
Middle Aged
;
Rectal Neoplasms
;
pathology
;
surgery
;
Rectum
;
surgery
;
Stomach Neoplasms
;
pathology
;
surgery
;
T-Lymphocyte Subsets
;
pathology
;
T-Lymphocytes, Cytotoxic
;
pathology
;
Th1 Cells
;
pathology
;
Th2 Cells
;
pathology
8.Effect of RDP1258 on survival of rat cardiac allograft
Zhigang CUI ; Zehou WANG ; Ming YUE
Chinese Journal of Organ Transplantation 1996;0(04):-
Objective To investigate the effects of RDP1258 on survival of rat cardiac allograft. Methods RDP1258 was synthesized and the model of rat heart abdominal transplantation was established. Animals were divided into four groups. Group 1 received no immunosuppression. Group 2 received CsA alone. Group 3 received RDP1258 alone. Group 4 received RDP1258 and subtherapeutic CsA. In all cases RDP1258 was administrated intraperitoneally and CsA was gavaged. Light and electron microscopic examinations were taken . Transplanted hearts were monitored daily by direct palpation. Results The purity of synthesized RDP1258 was over 95 % and the molecular weight was in accord with theoretical value. The histology and the ultrastructure changed little in grafts in group 3 and group 4. Survival of rat cardiac allograft was significantly prolonged in group 4. Conclusions RDP1258 can suppress acute rejection. Perioperative administration of RDP1258 in combination with CsA can significantly prolong survival of rat cardiac allograft.
9.Determination of N,N-dimethylformamide in Air by Capillary Gas Chromatography
Hanmei TIAN ; Rong CUI ; Ming RUAN
Journal of Environment and Health 2007;0(09):-
0.999) . The limit of detection was 4.0 ?10-4 ?g. The relative standard deviation was 0.9%-7.5% and the desorption efficiency of DMF was 86.5%-94.0%. Conclusion The method is applicable to the determination of DMF in the air.
10.Teaching of Tuina Manual Techniques in High Occupational Sports Colleges
Jianyou JI ; Ming CUI ; Guoqi HUANG
Journal of Acupuncture and Tuina Science 2009;7(2):120-122
Objective:To enhance the teaching quality of the Tuina Manual Techniques in the high occupational sports colleges.Methods:Performed by multiple educational reforms,including rearrangement of the teaching contents based upon the cognition rules,PBL teaching ideas are involved to improve the teaching condition,increase the multimedia and practical teaching,enrich the teaching resources,and revise the examination and evaluation protocol,etc.Results and Conclusion:By various reforms,the students can not only leam the professional skills,and also elevate their abilities in analyzing and solving their problems.