From May to November 2001, among 32 241 patients met 3 772 who had allergic dematology inflamation of many causes, 35 of them contacted cosmetics. In general, 91.43% of the patients are women and 8.57% are men, 51.4% range from 20-29 years old of age. 62.86% are state servants and students. 68.6% of the patients were affected after contacting cosmetic for one year. 65.71% are affected on the face and 37.14% had an antecedent of allergy.
Epidemiology ; Allergic ; Cosmetics

In the field of surgery, there are a large number of studies in progress for more minimally invasive surgery and cosmetic improvements. Among these studies, NOTES (natural orifice transluminal endoscopic surgery) and single-port laparoscopic surgery are the 2 studies attracting the most attention. Single-port laparoscopic surgery is a procedure where laparoscopic surgery is performed through a single incision at the umbilicus or another region. Until now, many kinds of surgeries were performed by single-port laparoscopy. In this article, the authors attempt to explain the procedures of single-port laparoscopic appendectomy in detail based on our experiences.
Appendectomy ; Cosmetics ; Laparoscopy ; Umbilicus

Retrospective and cross-sectional study on 60 patients with cosmetic allergy treated at Department of Allergology – Clinical Immunology and National Institute of Dermatology and Venerology in Bach Mai Hospital between January 1992 and February 2004. Results: there are plentiful and diversified cosmetics caused allergic reactions with 30 types divided into 6 groups: skin care cream (33.3%), dye hair (20.0%), powder foundation, toilet soap, other creams (21.7%), and other cosmetics. Allergic reactions commonly occurred in females, with common clinical symptoms such as itching, erythema, prurigo, vesicle, infected vesicle, edema, etc. They were treated by corticosteroid, anti-histamine H1, antibiotics, solution infusion, vitamin and other drugs. There was no death or more serious allergic reactions.
Hypersensitivity ; Cosmetics ; Epidemiology

Although finger tip replantation is popularized nowadays, it is not easy operations even for experienced surgeons. The indication for replantation to treat fingetip amputation is still controversial, but I think replantation for function and cosmetic absolute indication. This paper will discuss about methods of fingertip replantation and unexpected complications on soft tissue after operation.
Amputation ; Cosmetics ; Fingers ; Replantation

The use of cosmetics in the crowd has the long-term characteristics. The adverse reactions of cosmetics reported in other country in the world suggest that human patch tests and short-term human using test may not be sufficient to evaluate the safety of high-risk new cosmetic raw ingredients, and long-term human using test should be conducted for evaluation. Therefore, this article reviews the key factors that affect long-term human trial trials, such as site of use, single-use amount, frequency of use, duration of use, and subject conditions, providing supportive evidence for standardized safety evaluation standards for long-term human using test of cosmetics.
Humans ; Cosmetics ; Human Experimentation

The use of cosmetics in the crowd has the long-term characteristics. The adverse reactions of cosmetics reported in other country in the world suggest that human patch tests and short-term human using test may not be sufficient to evaluate the safety of high-risk new cosmetic raw ingredients, and long-term human using test should be conducted for evaluation. Therefore, this article reviews the key factors that affect long-term human trial trials, such as site of use, single-use amount, frequency of use, duration of use, and subject conditions, providing supportive evidence for standardized safety evaluation standards for long-term human using test of cosmetics.
Humans ; Cosmetics ; Human Experimentation

BACKGROUND: Graying of hair-a sign of aging-raises cosmetic concerns. Individuals with gray hair often look older than others their age; therefore, some dye their hair for aesthetic purposes. However, hair colorants can induce many problems including skin irritation, allergic reaction and hair-breakage. OBJECTIVE: This randomized, double-blind clinical trial was performed in order to examine the effects of APHG-1001, a compound including an extract from Pueraria lobata, on graying hair. METHODS: A total of 44 female subjects were randomly treated with either APHG-1001 or placebo twice daily for 24 weeks. Using the phototrichogram analysis, a count of newly developed gray hair was estimated. Investigator assessment and subject self-assessment were also performed in order to evaluate the efficacy of the compound. RESULTS: The mean number of newly developed gray hair at 24 weeks was 6.3/cm2 in the APHG-1001 group and 11.4/cm2 in the placebo group; the difference was statistically significant (p<0.05). However, the investigator assessment and subject self-assessment did not show any significant change in the gross appearance of hair grayness by the end of the study. No severe adverse events in either group were observed. Moreover, the incidence of adverse events did not differ between the groups. CONCLUSION: This clinical trial revealed that APHG-1001, which contains an extract of P. lobata, could prevent the development of new gray hair without any remarkable adverse effects. Thus, it can be considered as a viable treatment option for the prevention of gray hair.
Aging ; Antioxidants ; Cosmetics ; Female ; Hair ; Hair Color ; Hair Dyes ; Humans ; Hypersensitivity ; Incidence ; Pueraria ; Research Personnel ; Self-Assessment ; Skin

Milia en plaque (MEP) is an unusual and rare variant of milia characterized by tiny papules overlying an erythematous plaque. The majority of cases have been described as occurring around the ears. The histopathologic finding is consistent with milia. Despite its benign nature and lack of symptoms, MEP raises cosmetic concerns. We report a case of MEP occurring on the left 3rd finger, an unusual location, in a 2-year-old girl.
Cosmetics ; Ear ; Fingers ; Preschool Child

Desmoplastic trichoepithelioma is a rare benign adnexal tumor. Although it is a benign lesion, patients often want to treat it due to cosmetic concerns when it occurs in an easily visible site. For our two cases, topical 5% imiquimod was an attractive treatment option as it is applied by the patients themselves and it has minimal side effects, including leaving no scar. However, the lesions recurred after clinical remission. To the best of our knowledge, this is the only report on utilizing imiquimod to treat a benign adnexal tumor, and especially desmoplastic trichoepithelioma.
Aminoquinolines ; Cicatrix ; Cosmetics ; Humans ; Recurrence

Benzethonium chloride is quaternary ammonium compounds, which may cross-react with benzalkonium chloride. It has been used in the treatment of burns, ulcers, wounds, and infected dermatoses and also present in many cosmetics, deodorants, mouthwashes, dentifrices, lozenges, and ophthalmic preparations. Cetostearyl alcohol is used as emulsifiers and can be considered as preservatives. A 19-year-old female presented with well-demarcated adult-fist sized dark-reddish patch on the left shin. She had applied Senepul(R) (disinfectant solution) 3 months ago due to scratching wound and applied Travogen(R). Patch test with Korean standard series and the ingredients of used topical agents showed positive reactions to benzethonium chloride and cetostearyl alcohol.
Benzalkonium Compounds ; Benzethonium* ; Burns ; Dentifrices ; Deodorants ; Dermatitis, Allergic Contact* ; Female ; Humans ; Mouthwashes ; Patch Tests ; Quaternary Ammonium Compounds ; Skin Diseases ; Ulcer ; Wounds and Injuries ; Young Adult