PURPOSE:To analyze the clinical results of Goldmann applanation tonometry (GAT) and Pascal dynamic contour tonometry (PDCT) and the influences of central corneal thickness and keratometric power in eyes that underwent EpiLASIK or penetrating keratoplasty. METHODS: Measurements of intraocular pressure by GAT and PDCT as well as keratometric power and central corneal thickness were measured in 45 eyes that underwent penetrating keratopasty and 63 eyes that underwent EpiLASIK. These parameters were also measured in healthy eyes with no specific disorders to create a control group. RESULTS: In the keratoplasty group, the PDCT results were significantly higher than the GAT results by 1.22+/-2.84 mmHg (p=0.006), but neither method showed a significant correlation with CCT or keratometric power. In the EpiLASIK group, PDCT was higher as 3.45+/-2.35 mmHg than GAT, and the corrected results of GAT were not different from the results of PDCT. In the control group, GAT was affected by central corneal thickness and keratometric power, but PDCT showed no significant relationship with these two factors. CONCLUSIONS: After EpiLASIK or penetrating keratoplasty, both of which change CCT and keratometric power, IOP cannot be accurately measured by GAT. In these patients, PDCT may play an important clinical role since it is less affected by corneal properties.
Corneal Transplantation ; Eye ; Humans ; Intraocular Pressure ; Keratoplasty, Penetrating ; Manometry ; Peptides

PURPOSE: This study was performed to evaluate the status of corneal transplantation in Korea over the last 6 years. METHODS: We evaluated the current status of domestic corneal transplantation using the data obtained from Korean Network for Organ Sharing (KONOS). We evaluated imported corneal transplantation by the number of corneal transplantations, the country of origin of imported cornea, the preserved state of corneas, the time from the death to transplantation and the result of corneal transplantation. The imported corneal transplantation data was obtained from the institution registered in KONOS and the institution recognized by the authers. RESULTS: The number of domestic cornea donations has not increased since 2000, but the number of transplantations using imported corneas has increased year by year. The quality of imported corneas was good. There was no difference in operation results when domestic corneas were used compared to the use of imported corneas from the USA, Australia or Sri Lanka. CONCLUSIONS: The increased use of imported corneas results of a deficiency in the number of domestic cornea donations. Social motivation should be used to increase domestic donations of corneas.
Australia ; Cornea ; Corneal Transplantation ; Keratoplasty, Penetrating* ; Korea ; Motivation ; Sri Lanka

PURPOSE: This study was performed to evaluate the status of corneal transplantation in Korea over the last 6 years. METHODS: We evaluated the current status of domestic corneal transplantation using the data obtained from Korean Network for Organ Sharing (KONOS). We evaluated imported corneal transplantation by the number of corneal transplantations, the country of origin of imported cornea, the preserved state of corneas, the time from the death to transplantation and the result of corneal transplantation. The imported corneal transplantation data was obtained from the institution registered in KONOS and the institution recognized by the authers. RESULTS: The number of domestic cornea donations has not increased since 2000, but the number of transplantations using imported corneas has increased year by year. The quality of imported corneas was good. There was no difference in operation results when domestic corneas were used compared to the use of imported corneas from the USA, Australia or Sri Lanka. CONCLUSIONS: The increased use of imported corneas results of a deficiency in the number of domestic cornea donations. Social motivation should be used to increase domestic donations of corneas.
Australia ; Cornea ; Corneal Transplantation ; Keratoplasty, Penetrating* ; Korea ; Motivation ; Sri Lanka

PURPOSE: To compare the accuracy and reproducibility of central corneal thickness measured by non-contact specular microscopy, ultrasound pachymetry, and Orbscan in the post-penetrating keratoplasty eyes. METHODS: Central corneal thickness was prospectively measured in eyes that had recieved penetrating keratoplasty at least 1 month before. One experienced technician measured all eyes using three methods; non-contact specular microscopy (Topcon SP-2000P; Topcon Corporation, Tokyo, Japan), Orbscan IIz (Orbtek; Bausch & Lomb, Rochester, USA), and ultrasound pachymetry (AL-2000; Tomey, Erlangen, Germany). Three consecutive measurements were performed using each method and the mean values and coefficient of variation were compared. RESULTS: The mean values of central corneal thickness were 550.7+/-63.3 micrometer with specular microscopy, 548.2+/-72.5 micrometer with ultrasound pachymetry, and 472.5+/-151.7 micrometer with Orbscan. There was no significant difference between the measurements obtained by specular microscopy and ultrasound pachymetry (p=0.53), and both methods showed high reproducibility. The corneal thickness measured by Orbscan was remarkably variable and in some patients, Orbscan was unable to measure corneal thickness. CONCLUSIONS: Non-contact specular microscopy appears to be an effective technique, potentially replacing ultrasound pachymetry for measuring central corneal thickness in the post-penetrating keratoplasty eyes.
Corneal Transplantation ; Humans ; Keratoplasty, Penetrating ; Microscopy ; Prospective Studies ; Ultrasonography

PURPOSE: Although the treatment of choice for bullous keratopathy is typically penetrating keratoplasty (PKP), not all patients are suited for this treatment. Thus, we evaluated the clinical effects of phototherapeutic keratectomy (PTK) on pain relief and on the improvement of photophobia and visual acuity in patients suffering from bullous keratopathy. METHODS: Twenty-three patients with bullous keratopathy who were awaiting PKP and suffering from ocular pain, photophobia, and cosmetic problems, were assessed. Twelve eyes were treated with PTK using the excimer laser (VISX STAR S3, Irvine, CA, U.S.A). Another 11 eyes were treated with eye drops or other conservative modalities. Statistically significant differences in pain relief, photophobia improvement, and cosmetic improvement between two groups were assessed by Fisher's exact test. RESULTS: Twelve eyes with bullous keratopathy underwent PTK. At post-operative 1 month, 83% of patients showed relief of pain, 75% of patients showed improvements in photophobia, and 58% of patients had increased visual acuity of one or more line. The overall satisfaction rate of PTK was 91%, but 67% of patients showed recurrence of corneal opacity and bullae formation at 6 months after the procedure. CONCLUSIONS: Phototherapeutic keratectomy (PTK) reduced pain and improved visual acuity slightly in patients with bullous keratopathy. This procedure could be considered a valuable alternative treatment modality while awaitng PKP.
Corneal Opacity ; Corneal Transplantation ; Humans ; Keratoplasty, Penetrating ; Lasers, Excimer ; Ophthalmic Solutions ; Photophobia ; Recurrence ; Visual Acuity

To know the difference in graft rejection after corneal transplantation between moist chamber and Optisol(Chiron Co. Irvine, CA, U.S.A.) as cornea preservation methods, we compared two groups involving 50 patients(71 eyes) who had undergone partially penetrating keratoplasty (PPKP) for the treatment of keratoconus or corneal dystrophy from 1991 to 1995. The graft rejection had occurred in 10 of 40 eyes(25%) in moist chamber group and 9 of 31 eyes(29%) in Optisol group, and the cases of permanent corneal opacity after rejection were 5 of 40 eyes(12.5%), 3 of 31 eyes(9.7%) respectively. No difference in the two groups was statistically significant(P<0.05). We found the fact that the difference did not exist in the results from graft rejection after PPKP using moist chamber method for short preservation period, or Optisol method for the relatively long period allowing serological and immunological screen test.
Cornea ; Corneal Opacity ; Corneal Transplantation ; Graft Rejection* ; Keratoconus ; Keratoplasty, Penetrating ; Transplants*

PURPOSE: To evaluate the factors that affect visual outcome and transplanted corneal endothelial cell density in eyes that have undergone cataract surgery after penetrating keratoplasty, and to compare surgical outcomes with those of a control group. METHODS: We conducted a retrospective review of case records of 20 eyes that had undergone cataract surgery between January 2003 and April 2006 after previous penetrating keratoplasty (group I) and 20 eyes that had undergone cataract surgery alone with low cornea endothelial cell density (group II). RESULTS: For both groups, the grade of nucleosclerosis affected postoperative best corrected visual acuity (BCVA) and the total phaco energy (phaco power X time) did not affect either BCVA or endothelial cell density. In group I, the factor that most affected change in corneal endothelial cell density after cataract surgery was the time interval between keratoplasty and phacoemulsification. Comparison of the surgical results showed an increase in BCVA for both groups, and the difference between the two groups was not statistically significant. However, group I showed a significantly greater decrease in corneal endothelial cell density than did group II. CONCLUSIONS: Our results suggest that the corneal endothelial cells of the eye having previously undergone penertrating keratoplasty are vulnerable to surgical insult occurring in procedures such as cataract surgery, and that the time interval between the two procedures can affect the change in endothelial cell density.
Cataract ; Cornea ; Corneal Transplantation ; Endothelial Cells ; Endothelium, Corneal ; Keratoplasty, Penetrating* ; Phacoemulsification* ; Retrospective Studies ; Visual Acuity

Lattice corneal dystrophy is a genetic disorder which deposits linear amyloid in corneal stroma and because of this deposition, patient, s visual acuity is decreased and recurrent corneal erosion occurs.There are three types of lattice corneal dystrophy, and among these types, especially type III has extremely low prevalence rate and quite different clinical findings compared with type I and II, and never has been reported in Korea.We report one case of type III lattice corneal dystrophy with aphakia who had been managed by penetrating keratoplasty with secondary PCL implantation.
Amyloid ; Aphakia* ; Corneal Stroma ; Corneal Transplantation* ; Humans ; Keratoplasty, Penetrating ; Prevalence ; Visual Acuity

PURPOSE: To report the resolution of a massive suprachoroidal hemorrhage after penetrating keratoplasty by sclerotomy. CASE SUMMARY: A 64-year-old man with a corneal opacity in the left eye underwent penetrating keratoplasty. On the first postoperative day, a massive suprachoroidal hemorrhage was detected. After two surgical drainage procedures, the suprachoroidal hemorrhage subsided and the graft survived. His visual acuity was 20/240 two months post-operation. CONCLUSIONS: We report a patient with massive suprachoroidal hemorrhage after penetrating keratoplasty that was improved by surgical drainage procedures.
Corneal Opacity ; Corneal Transplantation ; Drainage ; Hemorrhage* ; Humans ; Keratoplasty, Penetrating* ; Middle Aged ; Transplants ; Visual Acuity

Penetrating keratoplasty with or without intraocular lens implantation is necessary to restore a vision of an eye with aphakic bullous keratopathy. We analyzed surgical outcomes in eleven aphakic bullous keratopathy patients(11, eyes) who received penetrat-ing keratoplasty with scleral-fixated posterior chamber lens(PCL)at Kangnam St.Mary's hospital from January, 1989 to December 1991 and followed up more than 1 year Eight of eleven eyes showed the postoperative corrected VlSlOn of 0.3 to 0.8 at postoperative one year. The cuases of poor vision below 0.3 were age-related macular degeneration(1 eye), graft failure(I eye) and diabetic retinopathy(1 eye). At one year after surgery, mean spherical equivalent was-1.12, mean astigmatism was 4.21D and percent loss of corneal endothelium was 35.5%. Graft rejection(3 eyes) and secondary glaucoma(1 eye) were occured during the postoplasty with scleral-fixated PCL can be an excellent surgical technique to get visual rehabilitaion of patients with an aphakic bullous keratopathy.
Astigmatism ; Corneal Transplantation ; Endothelium, Corneal ; Humans ; Keratoplasty, Penetrating* ; Lens Implantation, Intraocular ; Transplants