IOP was measured with 3 different tools, namely, the Pulsair peumotonometer(A), the Oculab Tono-pen(B), and the Goldmann applanation tonometer(C), in order to evaluate the clinical usefulness of each. 174 eyes without corneal opacity and corneal edema were measured. The results were as follows; 1. The correlation coefficient was 0.85(P<0.005) between A and C, 0.82(P<0.005) between B and C and 0.83(P<0.005) between A and B. The correlative formulas between the measurements of IOPs were produced to be: A = 0.73 X C + 5.49, B = 0.76 X C + 5.33, A = 0.78 X B + 3.87. 2. At low IOPs(<10 mmHg) as Measured by C(11 eyes), the correlation Coefficient was 0.81(P<0.05) between B and C. However, A and B valuse tended to be highter than C value. 3. At relatively high IOPs(>20 mmHg)as measured by C(56 eyes), the correleation coefficient was 0.83 between A and C(P<0.0001) and 0.82(P<0.0001) between B and C. However, A and B values tended to be lower than c value. 4. At relatively high IOPs(>20 mmHg)as measurde by C, the sensitivity of A was 60.53% and that of B was 73.68%. According to this study, no significant difference could be found among these three tools. However, at low IOPs(<10 mmHg), the Oculab Tono-pen and Pulsair pneumotonometer tended to show higher values than the Goldmann applanation tonometer. In case of relatively high IOPs(>20 mmHg as measured by the Goldman tonometer), the Oculab Tono-pen and Pulsair pneumotonometer tended to show lower values than the Goldmana applanation tono meter and the sensitivity of the Oculab Tono-pen showed higher than that of the Pulsair pneumotonomer.
Corneal Edema ; Corneal Opacity ; Intraocular Pressure

We have investigated the therapeutic effectiveness of T-lens(Soflens(R)) in 105 patients(110 eyes) with various corneal diseases. The results are as follows: 1. Cornea diseases, which revealed the good therapeutic effectiveness, are ccrneal perforation, postoperative uses, corneal ulcer, corneal erosion, and corneal edema. 2. Corneal disease, which revealed the rapid therapeutic effectiveness, is corneal edema. 3. Corneal diseases, which revealed no response, are neuroparalytic keratitis and radiation keratitis.
Cornea ; Corneal Diseases* ; Corneal Edema ; Corneal Ulcer ; Keratitis ; Therapeutic Uses*

PURPOSE: To compare the effects of phacodynamic parameters on postoperative corneal edema between 2.8 mm and 2.2 mm microincisional coaxial cataract surgery. METHODS: A prospective randomized study design was conducted and included 144 cases randomly divided into 2 coaxial cataract surgery groups based on incision size, a 2.8 mm incision (n = 72) or a 2.2 mm microincision (n = 72). The cataract was graded using the lens opacity classification system (LOCS III). The total ultrasound time (TUT), cumulative dispersed energy (CDE), average torsional amplitude (ATA), fluid amount, and case time were measured for each surgery. Central corneal thickness (CCT) was measured preoperatively, and 1 day and 1 month postoperatively. Intraoperative parameters were correlated with postoperative corneal edema. RESULTS: The average nuclear opacity, intraoperative parameters, and postoperative corneal edema did not differ significantly between the 2 surgical groups. Regression analysis showed corneal edema to be significant in ATA (p = 0.028) in the standard (2.8-mm incision) coaxial group, whereas edema was significantly different with TUT (p = 0.001), CDE (p = 0.001), fluid amount (p = 0.021), and case time (p = 0.027) in the microcoaxial (2.2-mm microincision) group. CCT returned to baseline with an increase of 1.8% at 1 month. CONCLUSIONS: In the microcoaxial group, sustained ultrasound exposure and prolonged case time caused moderate postoperative corneal edema, while ATA was a significant factor in the standard coaxial group. These data can be used to devise an effective surgical strategy for cataract treatment.
Cataract ; Corneal Edema ; Edema ; Phacoemulsification ; Prospective Studies

The purpose of this study was to investigate the therapeutic effects of early administration of 5%NaCl on corneal edema induced by intracameral injection of 2%lidocaine. All thirty eyes of 30 rabbits were randomly assigned to one of the six study groups (group A and a, group B and b, group C and c). One of tenth ml of 2%lidocaine was injected intracamerally at right eyes of thirty rabbits. In group A, they were treated with 5% NaCl every 2 hours from 24 hours after the operation. In group B, from 12 hours and in group C, immediately after the operation. In control group a, b, c, they were treated with same method except balanced salt solution instead of 5%NaCl. Central corneal thickness (CCT)was measured before operation and after operation every 6 hours until the three successive records had no demonstrable changes compared to baseline levels. A statistically significant decrease of the CCT was found in group A compared with group a from 78 hours to 138 hours postoperatively. There was a statistically significant decrease of the CCT in the group B compared with that in group b from 42 hours after the operation. Recovery time to the preoperative levels was reduced by 66 hours. There was a statistically significant decrease of the CCT in the group C compared with that in group b from 18 hours after the operation. Recovery time to the preoperative levels was reduced by 84 hours. Early initiation of treatment with 5%NaCl following intracameral injection of 2%lidocaine reduced not only the amount of the corneal edema but also the recovery to the preoperative levels.
Corneal Edema* ; Ophthalmic Solutions* ; Rabbits*

21 patients suffering from bullous keratopathy were fitted with T-Iens (Soflens) continuously for average 12 months without adverse effect. The T-Iens (Soflens) produced dramatic relief of ocular pain occurred in 9 patients among the 12 paitents. The T-Iens (Soflens) produced mild clinical improvement of vesicle. visual auity and corneal edema.
Corneal Edema ; Humans ; Therapeutic Uses*

No abstract available.
Cornea ; *Corneal Edema ; Edema ; Humans ; *Macular Edema ; Pseudophakia ; Visual Acuity

No abstract available.
Cornea ; *Corneal Edema ; Edema ; Humans ; *Macular Edema ; Pseudophakia ; Visual Acuity

PURPOSE: To compare preoperative and postoperative thickness and to investigate the difference in the thickness change of corneal epithelium and stroma after cataract surgery through scleral tunnel incision. METHODS: Forty eyes of forty patients who were 40 years old or older and underwent small-incision superior scleral tunnel cataract surgery with phacoemulsification were included. Using the RTVue instrument (Optovue Inc., Fremont, CA, USA), corneal epithelial (ET) and stromal thicknesses (ST) of all subjects were measured preoperatively and at 3 days, 1 week, and 1 month postoperatively. Thicknesses were classified into 3 zones according to the distance from the vertex: central zone (within 2 mm), paracentral zone (2-5 mm diameter) and midperipheral zone (5-6 mm diameter). RESULTS: Mean central ST was 486.68 ± 25.15 µm, 535.16 ± 48.13 µm, 515.98 ± 44.07 µm, and 502.28 ± 34.87 µm preoperatively, and at 3 days, 1 week, and 1 month postoperatively, respectively (p < 0.001 for all). ST showed significant thickening in all three zones from 3 days to 1 month postoperatively (p < 0.001 for all). Mean central, paracentral, and midperipheral ET was 52.13 ± 3.41 µm, 50.42 ± 2.97 µm, 49.12 ± 3.05 µm at preoperatively and 51.03 ± 3.63 µm, 48.96 ± 3.62 µm, 47.67 ± 3.81 µm at 1 month postoperatively, respectively (p = 0.061, 0.006, 0.001, respectively), while there were no signficant changes in all three zones at 3 and 7 days postoperatively. Changes in ET and ST were prominent at the superotemporal incision site. CONCLUSIONS: After scleral tunnel cataract surgery, corneal edema was observed in the stroma immediately after surgery. There was no significant change at early times after surgery in the epithelium, and there was a decrease in the peripheral cornea at 1 month postoperatively. The change in ET was considered a compensatory change due to stromal edema and appeared between 1 week to 1 month postoperatively.
Cataract* ; Cornea ; Corneal Edema ; Corneal Stroma ; Edema ; Epithelium ; Epithelium, Corneal ; Humans ; Phacoemulsification

The effect of topical perfluorophenanthrene on corneal neovascularization was studied at chemically induced corneal burn on the rats. A central corneal burn was produced with 10% NaOH. Right eye was treated with perfluorophenanthrene and gentamicin eye drops four times a day for five days, the left with balanced salt solution and gentamicin eye drops as control. After five days treatment the rats were sacrified, and the tissue slide were prepared for microscopIc examination. Using slide projector the tissue slide were projected and magnified on the screen. The number of corneal new vessels, the distance of new vessel from the limbus, and the degree of increased corneal thickness were calculated in both groups. As the result there were no statistical difference between two groups. Analysis using ANOVA program showed the fact that statistically significant correlationship between the degree of corneal thickness and the number of the new vessels and the distance from the limbus were found. The result could confirm the mechanism of corneal neovascularization that disarrangement of the compact corneal tissue could allow the formation of the new vessels.
Animals ; Burns ; Corneal Edema ; Corneal Neovascularization* ; Gentamicins ; Ophthalmic Solutions ; Rats*

The objective of this study was to examine the effects of pars plana vitrectomy on the corneal endothelium. Thirty-one patients scheduled for pars plana vitrectomy were enrolled in this prospective study. Specular microscopic examination to check central corneal thickness (CCT) and central corneal endothelial density (CCED) was underwent at preoperatively and 1 week, 1 month, 2 months postoperatively. The duration of intravitreal irrigation and the volume of solution were checked also. Transient corneal edema and decrease in endothelial cell density with statistical significance was observed at 1 week postoperatively. We found that neither duration of intraocular irrigation nor the volume of solution used is related with corneal changes. The eyes with combined lensectomy showed more severe corneal edema and significant greater reduction of endothelial cell density at 1 month and 2 months postoperatively compared to phakic eyes. Diabetic eyes also showed a significant greater reduction of endothelial cell density at 2 months postoperatively compared to nondiabetic eyes.
Corneal Edema ; Endothelial Cells ; Endothelium, Corneal* ; Humans ; Prospective Studies ; Vitrectomy*