A clinical evaluation of the chemotherapy (INH, PAS and SM) on the 16 patients with renal tuberculosis for the period of 9 months to 4 years was performed. The results obtained were summarized as follows; 1) Of the 16 cases with renal tuberculosis, minimal lesion was found in only one case. moderately advanced in 6, and far advanced in 9. 2) In the case of the minimal lesion, no tubercle bacilli were detected by microscopic examination .after the triple therapy for 3 months. It was suggested that the minimal lesion would require at 1eaet 6 months to be cured by the chemotherapy. 3) Five of the 6 cases with the moderately advanced lesion were cured (83%), and at least 12 months were required for the moderately advanced lesion to be cured. 4) In the 9 cases of the far advanced lesion, only one case was cured, two were on the healing process, three were exacerbated even after the therapy for 6 months, and the remaining three were progressed to those with non-visualizing kidneys 9 to 12 months after the therapy. 5) Five of the 6 exacerbated far advanced lesions were associated with ureteral strictures, and thus the ureteral stricture may be an important factor in determining the prognosis of the renal tuberculosis. For the far advanced lesions progressed to the non-visualizing kidneys in spite of the chemo-therapy, surgical interventions are likely to be more favorable.
Constriction, Pathologic ; Drug Therapy* ; Humans ; Kidney ; Prognosis ; Tuberculosis, Renal* ; Ureter

Adolescent ; Constriction, Pathologic ; Coronary Vessel Anomalies ; therapy ; Humans ; Male ; Stents

Constriction, Pathologic ; Fibrosis ; Humans ; Lung ; Mediastinitis/therapy* ; Sclerosis

Humans ; Tenosynovitis/therapy* ; Tendons ; Constriction, Pathologic ; Primary Health Care

Humans ; Renal Artery ; Constriction, Pathologic ; Hypertension, Renovascular/therapy* ; Vascular Diseases ; Renal Artery Obstruction/therapy* ; Embolization, Therapeutic

Crohn's disease is a chronic and relapsing disease that is not easily controlled with medications. It is characterized by progressive transmural inflammation, and ultimately leads to stricture and penetrating complications requiring surgery. Over the past decades, the prevalence of Crohn's disease has gradually increased in Korea. Conventional treatments with aminosalicylates, steroids, and immunosuppressants are inadequate to control its symptoms and complications. Biologic therapy shows promise for controlling disease activity and promoting mucosal healing. Despite the development of several medical therapies, the treatment of Crohn's disease remains challenging. Individually tailored treatment according to an endoscopic or symptomatic assessment is required.
Biological Therapy ; Constriction, Pathologic ; Crohn Disease* ; Diagnosis* ; Immunosuppressive Agents ; Inflammation ; Korea ; Prevalence ; Steroids

Since 1984, 9 months regimen of chemotherapy have been adopted for the treatment of 22 patients (15 men and 7 women) suffering from genitourinary tuberculosis. Age range of patients was from 16 years to 68 years with average of 34.7 years. Urine culture for AFB were positive in 12 patients (54.6 %) and the other patients were diagnosed by radiologic, cystoscopic and histopathologic examinations In all 12 patients who had positive urine culture for AFB, urine has been sterilized within 3 months after treatment. The surgical managements with chemotherapy were performed in 9 patients. Toxic hepatitis due to drugs developed in 1 patient. The cost of chemotherapeutics spent in long term chemotherapy was 3 to 4 times higher than in short term chemotherapy. `There were no relapse bacteriologically during the follow up periods (3 to 22 months, average 10.4 months), but one patient has undergone ureteroneocystostomy due to UVJ stricture after completion of chemotherapy.
Constriction, Pathologic ; Drug Therapy* ; Drug-Induced Liver Injury ; Follow-Up Studies ; Humans ; Male ; Recurrence ; Tuberculosis*

Placement of the self-expandable metallic stents for palliative treatment of malignant esophagogastric strictures has been thought to be easy, fast and effective method than conventional methods (bypass procedures, radiation therapy, laser treatment, esophageal intubation, etc.). The expandable metallic stent tubes were found to overcome some of the limitations of nonexpandable conventional tubes. Their implantation is better tolerated and safer than that of nonexpandable tubes, because the risks of migration and perforation are lower.On our knowledge, there has been no report of pyloric obstruction after this metallic stent insertion.We hereby report a case of pyloric obstruction caused by a migrated self-expandable metallic stent for palliative treatment of malignant esophageal stricture.
Constriction, Pathologic ; Deglutition Disorders* ; Esophageal Neoplasms ; Esophageal Stenosis ; Intubation ; Laser Therapy ; Palliative Care ; Stents*

Non-operative palliative treatment for malignant colonic obstruction can sometimes be accomplished by the insertion of anorectal tube, endoscopic balloon dilation or endoscopic laser therapy. But these methods have some disadvantages, such as limitaation of activity, need of repetitive treatment and high-risk of perforation. Endoscopic prosthesis is generally accepted as a safe, effective palliative treatment for malignant esophageal stricture, because this method has no above disadvantages. Neverthless, there is only a few experence with endoecopic prosthesis in malignant colorectal stricture over the world. We report two cases which were safely, effectively performed endoscopic prosthesis in palliative treatment for their malignant rectal strictures.
Colon ; Constriction, Pathologic* ; Esophageal Stenosis ; Laser Therapy ; Palliative Care ; Prostheses and Implants*

The efficacy and safety of catheter ablation for the management of atrial fibrillation (AF) has been improved in recent years. Radiofrequency (RF) catheter ablation for maintaining sinus rhythm is superior to the current antiarrhythmic drug therapy in selected patients. Pulmonary vein isolation (PVI) is the cornerstone of various catheter ablation strategies. It is well recognized that pulmonary vein (PV) antrum contributes to the AF initiation and/or perpetuation. Since PV stenosis is a complication of ablation within a PV, the ablation site for PVI has shifted to the junction between the left atrium and the PV rather than the ostium of the PV. However, PV reconnection after ablation is the major cause of recurrence of AF. The recovery of PV conduction could be caused by anatomical variations such as the failure to produce complete transmural lesion or gaps at the ablation line due to the transient electrophysiologic effects from the RF ablation. In this review, we discussed several factors to be considered for the achievement of the best PVI, including clinical aspects and technical aspects.
Atrial Fibrillation ; Catheter Ablation ; Constriction, Pathologic ; Drug Therapy ; Heart Atria ; Humans ; Pulmonary Veins* ; Recurrence