Adolescent ; Constriction, Pathologic ; Coronary Vessel Anomalies ; therapy ; Humans ; Male ; Stents

A clinical evaluation of the chemotherapy (INH, PAS and SM) on the 16 patients with renal tuberculosis for the period of 9 months to 4 years was performed. The results obtained were summarized as follows; 1) Of the 16 cases with renal tuberculosis, minimal lesion was found in only one case. moderately advanced in 6, and far advanced in 9. 2) In the case of the minimal lesion, no tubercle bacilli were detected by microscopic examination .after the triple therapy for 3 months. It was suggested that the minimal lesion would require at 1eaet 6 months to be cured by the chemotherapy. 3) Five of the 6 cases with the moderately advanced lesion were cured (83%), and at least 12 months were required for the moderately advanced lesion to be cured. 4) In the 9 cases of the far advanced lesion, only one case was cured, two were on the healing process, three were exacerbated even after the therapy for 6 months, and the remaining three were progressed to those with non-visualizing kidneys 9 to 12 months after the therapy. 5) Five of the 6 exacerbated far advanced lesions were associated with ureteral strictures, and thus the ureteral stricture may be an important factor in determining the prognosis of the renal tuberculosis. For the far advanced lesions progressed to the non-visualizing kidneys in spite of the chemo-therapy, surgical interventions are likely to be more favorable.
Constriction, Pathologic ; Drug Therapy* ; Humans ; Kidney ; Prognosis ; Tuberculosis, Renal* ; Ureter

Constriction, Pathologic ; Fibrosis ; Humans ; Lung ; Mediastinitis/therapy* ; Sclerosis

Humans ; Tenosynovitis/therapy* ; Tendons ; Constriction, Pathologic ; Primary Health Care

Humans ; Renal Artery ; Constriction, Pathologic ; Hypertension, Renovascular/therapy* ; Vascular Diseases ; Renal Artery Obstruction/therapy* ; Embolization, Therapeutic

Renal tuberculosis commonly involves the urinary tract and results in multifocal fibrosis and stricture. Rarely, it presents as a renal mass with or without urinary tract abnormality. The radiologic features of this rare pseudotumor have not been sufficiently described in the previous literature, and we now report a case of tuberculosis presenting as an isolated renal mass and multiple hepatic nodules without evidence of associated urinary tract abnormality. The condition mimicked malignant neoplastic disease and occurred in a patient who had undergone chemotherapy for leukemia.
Constriction, Pathologic ; Drug Therapy ; Fibrosis ; Humans ; Immunocompromised Host* ; Leukemia ; Tuberculosis ; Tuberculosis, Renal* ; Urinary Tract

Since 1984, 9 months regimen of chemotherapy have been adopted for the treatment of 22 patients (15 men and 7 women) suffering from genitourinary tuberculosis. Age range of patients was from 16 years to 68 years with average of 34.7 years. Urine culture for AFB were positive in 12 patients (54.6 %) and the other patients were diagnosed by radiologic, cystoscopic and histopathologic examinations In all 12 patients who had positive urine culture for AFB, urine has been sterilized within 3 months after treatment. The surgical managements with chemotherapy were performed in 9 patients. Toxic hepatitis due to drugs developed in 1 patient. The cost of chemotherapeutics spent in long term chemotherapy was 3 to 4 times higher than in short term chemotherapy. `There were no relapse bacteriologically during the follow up periods (3 to 22 months, average 10.4 months), but one patient has undergone ureteroneocystostomy due to UVJ stricture after completion of chemotherapy.
Constriction, Pathologic ; Drug Therapy* ; Drug-Induced Liver Injury ; Follow-Up Studies ; Humans ; Male ; Recurrence ; Tuberculosis*

Crohn's disease is a chronic and relapsing disease that is not easily controlled with medications. It is characterized by progressive transmural inflammation, and ultimately leads to stricture and penetrating complications requiring surgery. Over the past decades, the prevalence of Crohn's disease has gradually increased in Korea. Conventional treatments with aminosalicylates, steroids, and immunosuppressants are inadequate to control its symptoms and complications. Biologic therapy shows promise for controlling disease activity and promoting mucosal healing. Despite the development of several medical therapies, the treatment of Crohn's disease remains challenging. Individually tailored treatment according to an endoscopic or symptomatic assessment is required.
Biological Therapy ; Constriction, Pathologic ; Crohn Disease* ; Diagnosis* ; Immunosuppressive Agents ; Inflammation ; Korea ; Prevalence ; Steroids

PURPOSE: To evaluate the classification of punctal stenosis based on the shape of the external punctum, clinical characteristics and histopathologic features. METHODS: Patients who experienced tearing and were diagnosed with punctal stenosis were evaluated in this study. Punctal stenosis was classified according to the shape of the lower external punctum, which included membranous type, slit type, horseshoe type, and pinpoint type. Tear meniscus height, 2% fluorescein dye disappearance test and lacrimal pathway irrigation were measured or performed. For treatment, a punctal snip operation and silicone tube placement were performed, and the peripunctal histopathological findings were evaluated. RESULTS: Punctal stenosis was classified into four types: membranous type (17 eyes, 21.5%), slit type (11 eyes, 13.9%), horseshoe type (25 eyes, 31.6%), and pinpoint type (26 eyes, 32.9%). The tear meniscus was significantly higher, and the 2% fluorescein dye disappeared significantly more slowly in the punctal stenosis group. However, correlation of the tear meniscus height and 2% fluorescein dye disappearance test with the punctum shape was not statistically significant. A history of previous chemotherapy was significantly associated with the occurrence of punctal stenosis, especially the membranous type (p < 0.05). Histopathologic evaluation of the punctum showed differences between the punctum types. Pinpoint puncta exhibited a high density of muscle fibers, while they were faintly visible in the membranous type. CONCLUSIONS: Acquired punctal stenosis has various shapes, and the major types of stenotic puncta exhibited unique histopathologic features. Punctal stenosis and its pathophysiology may be related to multiple factors, such as age and systemic 5-fluorouracil chemotherapy history.
Classification* ; Constriction, Pathologic* ; Drug Therapy ; Fluorescein ; Fluorouracil ; Humans ; Lacrimal Apparatus ; Lacrimal Apparatus Diseases* ; Silicon ; Silicones ; Tears

Although most of the patients with endobronchial tuberculosis have some degree of bronchial stenosis, more aggressive treatment is needed to restore the patency of the involved tracheobronchial tree for some patients not responding well to antituberculous chemotherapy combined with steroids. In our first case, we resected stenotic trachea in a 42 years old women who showed overgrowing granulation tissue through the modified Gianturco stent wire which was previously inserted and anastomosed end to end. Another case was a 37 years old male with left main bronchial restenosis complicated after inserting a Strecker stent and sleeve left upper lobectomy was performed.
Adult ; Constriction, Pathologic* ; Drug Therapy ; Female ; Granulation Tissue ; Humans ; Male ; Stents* ; Steroids ; Trachea ; Tuberculosis