2.Study on the efficacy graded-disease-spectrum of acupuncture and moxibustion by the fuzzy comprehensive evaluation techniques: musculoskeletal and connective tissue diseases.
Yuan-Hao DU ; Jun XIONG ; Bo LI ; Yan-Long XU ; Wei-Hong LIU ; Ying LI ; Jing LI ; Lei SHI ; Xiao-Miao LIN ; Li XIAO
Chinese Acupuncture & Moxibustion 2011;31(3):271-275
The descriptive cross sectional surveys were carried out among the outstanding clinical physicians in the field of acupuncture and moxibustion by using the survey sampling. The fuzzy comprehensive evaluation techniques was applied to evaluate the opinions of clinical experts in the field of acupuncture and moxibustion in order to classify the spectrum of diseases related to the musculoskeletal and connective tissue. After the statistical analysis on sixty-four diseases with 104 subtypes, the spectrum of diseases were determined as grade I spectrum of diseases with 13 subtypes of diseases, grade II spectrum of diseases with 51 subtypes of diseases, grade III spectrum of diseases with 10 subtypes of diseases, and grade IV spectrum of diseases with 30 subtypes of diseases. The outcomes reveal that acupuncture and moxibustion therapy have been applied widely for musculoskeletal diseases and connective tissue related diseases.
Acupuncture Therapy
;
methods
;
Bone Diseases
;
therapy
;
Connective Tissue Diseases
;
therapy
;
Cross-Sectional Studies
;
Humans
;
Moxibustion
;
methods
;
Muscular Diseases
;
therapy
;
Surveys and Questionnaires
3.Case of Raynaud Syndrome after the Use of Methimazole.
Yunkyung KIM ; Hee Sang TAG ; Geun Tae KIM ; Seung Geun LEE ; Eun Kyung PARK ; Ji Heh PARK ; Seong min KWEON ; Song I YANG ; Jeong Hoon KIM
Journal of Rheumatic Diseases 2018;25(3):203-206
Raynaud syndrome is a medical condition that causes pain, numbness, and changes in skin color at the distal extremities. Raynaud syndrome can be subdivided into primary Raynaud's and secondary Raynaud's. The former is diagnosed when the cause is unknown and the latter is caused by an underlying condition, such as connective tissue diseases, injury, smoking, or certain medications. Both cancer chemotherapy and β-blockers are relatively common causes of Raynaud syndrome but there are no reports of its association with methimazole administration. The authors encountered a 43-year old woman with hyperthyroidism who developed digital ulcers associated with Raynaud syndrome after a methimazole treatment. Her digital ulcers and Raynaud syndrome were improved after methimazole was replaced with propylthiouracil and conventional therapy. This paper reports this case along with a review of the relevant literature.
Connective Tissue Diseases
;
Drug Therapy
;
Extremities
;
Female
;
Humans
;
Hyperthyroidism
;
Hypesthesia
;
Methimazole*
;
Propylthiouracil
;
Skin Pigmentation
;
Smoke
;
Smoking
;
Ulcer
4.Crohn's Disease in a Patient Undergoing Hemodialysis Caused by IgA Nephropathy.
Biro KIM ; Jae Won YANG ; Joung Wook CHOI ; Young Sub KIM ; Jong Myeong YU ; Seung Ok CHOI ; Byoung Geun HAN
Korean Journal of Nephrology 2009;28(5):519-524
IgA nephropathy is usually localized to the kidney, however, it can accompany systemic disease, including gastrointestinal disease, skin disease, connective tissue disease, and malignant tumor. In some patients with IgA nephropathy which manifested as an extraintestinal symptom of Crohn's disease, recovery of renal function was achieved following treatment of Crohn's disease. The pathophysiology of each disease remains unclear. According to some studies, however, immunological, genetic, and environmental factors may be involved in a complex manner. In patients receiving renal replacement therapy for treatment of renal dysfunction due to IgA nephropathy, occurrence of Crohn's disease as an extrarenal symptom has not been reported. We experienced a case of Crohn's disease which developed in a patient receiving hemodialysis for treatment of end-stage renal disease due to IgA nephropathy.
Connective Tissue Diseases
;
Crohn Disease
;
Gastrointestinal Diseases
;
Glomerulonephritis, IGA
;
Humans
;
Immunoglobulin A
;
Kidney
;
Kidney Failure, Chronic
;
Renal Dialysis
;
Renal Replacement Therapy
;
Skin Diseases
6.A Case of Pneumatosis Cystoides Intestinalis.
In Hae PARK ; Jae Hee CHO ; Chang Hwan CHOI ; Sang Kil LEE ; Tae Il KIM ; Ho Guen KIM ; Won Ho KIM
Korean Journal of Gastrointestinal Endoscopy 2005;30(6):336-339
Pneumatosis cystoides intestinalis (PCI) is a rare condition defined as the presence of multiple gas-filled cysts in the wall of gastrointestinal tract. The etiology and pathogenesis of PCI remain uncertain. It is associated with various medicosurgical conditions, including various pulmonary and gastointestinal diseases, connective tissue diseases and endoscopic procedures. The diagnosis is confirmed by endoscopic puncture and biopsy. PCI in adults, for the most part, show a benign clinical course and better prognosis if the associated disease is well controlled. Infantile PCI is more serious condition and especially associated with necrotizing enteritis. The treatment is usually conservative, However surgical intervention is needed when complications such as intussusception, obstruction, bleeding and perforation develope. We experienced a case of PCI found during the follow-up colonoscopy in a patient taken right hemicolectomy and systemic adjuvant chemotherapy due to colon cancer.
Adult
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Biopsy
;
Chemotherapy, Adjuvant
;
Colonic Neoplasms
;
Colonoscopy
;
Connective Tissue Diseases
;
Diagnosis
;
Drug Therapy
;
Enteritis
;
Follow-Up Studies
;
Gastrointestinal Tract
;
Hemorrhage
;
Humans
;
Intussusception
;
Pneumatosis Cystoides Intestinalis*
;
Prognosis
;
Punctures
7.Clinical research of multisystem inflammatory syndrome in children.
Ruo Hang WENG ; Wei Ying ZHAO ; Ting Yan HE ; Xiao Lin LI ; Xiao Qing LI ; Dong Mei ZHAO ; Yun Kun HAN ; Ping ZENG ; Xue Mei TANG ; Xiao Chuan WU ; Li LIU ; Jun YANG
Chinese Journal of Pediatrics 2023;61(12):1086-1091
Objective: To analyze the clinical characteristics of children with multisystem inflammatory syndrome (MIS-C) associated with SARS-CoV-2 in China, and to improve the understanding of MIS-C among pediatricians. Methods: Case series study.Collect the clinical characteristics, auxiliary examinations, treatment decisions, and prognosis of 64 patients with MIS-C from 9 hospitals in China from December 2022 to June 2023. Results: Among the 64 MIS-C patients, 36 were boys and 28 were girls, with an onset age being 2.8 (0.3, 14.0) years. All patients suffered from fever, elevated inflammatory indicators, and multiple system involvement. Forty-three patients (67%) were involved in more than 3 systems simultaneously, including skin mucosa 60 cases (94%), blood system 52 cases (89%), circulatory system 54 cases (84%), digestive system 48 cases (75%), and nervous system 24 cases (37%). Common mucocutaneous lesions included rash 54 cases (84%) and conjunctival congestion and (or) lip flushing 45 cases (70%). Hematological abnormalities consisted of coagulation dysfunction 48 cases (75%), thrombocytopenia 9 cases (14%), and lymphopenia 8 cases (13%). Cardiovascular lesions mainly affected cardiac function, of which 11 patients (17%) were accompanied by hypotension or shock, and 7 patients (12%) had coronary artery dilatation.Thirty-six patients (56%) had gastrointestinal symptoms, 23 patients (36%) had neurological symptoms. Forty-five patients (70%) received the initial treatment of intravenous immunoglobulin in combination with glucocorticoids, 5 patients (8%) received the methylprednisolone pulse therapy and 2 patients (3%) treated with biological agents, 7 patients with coronary artery dilation all returned to normal within 6 months. Conclusions: MIS-C patients are mainly characterized by fever, high inflammatory response, and multiple organ damage. The preferred initial treatment is intravenous immunoglobulin combined with glucocorticoids. All patients have a good prognosis.
Male
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Child
;
Female
;
Humans
;
Immunoglobulins, Intravenous/therapeutic use*
;
Blood Coagulation
;
COVID-19
;
China/epidemiology*
;
Connective Tissue Diseases
;
Coronary Aneurysm
;
Fever
;
Systemic Inflammatory Response Syndrome/therapy*
8.A Case of Acute Kidney Injury Associated with Rhabdomyolysis after Liposuction.
Chae Rim KIM ; Moon Ki HONG ; Woo Jin NAM ; Min Jee HAN ; Su Hyun KIM ; Do Hyoung KIM
Korean Journal of Medicine 2015;88(1):89-93
Rhabdomyolysis is defined as a skeletal muscle injury with release of muscle cell constituents into the plasma. It can occur in various diseases and conditions, including muscle strain, drug or alcohol abuse, connective tissue disease, excess exercise, or following surgery. Only one case of rhabdomyolysis has ever been associated with liposuction in Korea. We experienced a case of rhabdomyolysis that developed after liposuction surgery. The patient was a 39-year-old woman presenting with abdominal pain 1 day after liposuction. She was treated with general supportive care, including massive hydration and absolute bed rest. Renal replacement therapy was performed due to pulmonary edema. She, finally, recovered fully. Acute kidney injury caused by liposuction-induced rhabdomyolysis is a rare disease. Therefore, we present this case with a review of the literature.
Abdominal Pain
;
Acute Kidney Injury*
;
Adult
;
Alcoholism
;
Bed Rest
;
Connective Tissue Diseases
;
Female
;
Humans
;
Korea
;
Lipectomy*
;
Muscle Cells
;
Muscle, Skeletal
;
Plasma
;
Pulmonary Edema
;
Rare Diseases
;
Renal Replacement Therapy
;
Rhabdomyolysis*
9.Impact of COVID-19 on Clinical Operations and Management of Patients in a Singapore Immunodermatology Unit during the 'Circuit-Breaker' Period and Beyond.
Annals of the Academy of Medicine, Singapore 2020;49(11):919-921
Allergy and Immunology
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Ambulatory Care
;
Autoimmune Diseases/therapy*
;
COVID-19
;
Communicable Disease Control
;
Connective Tissue Diseases/therapy*
;
Delivery of Health Care/methods*
;
Dermatology
;
Humans
;
Immunosuppressive Agents/therapeutic use*
;
Patient Selection
;
SARS-CoV-2
;
Singapore
;
Skin Diseases, Vesiculobullous/therapy*
;
Telemedicine/methods*
;
Tertiary Care Centers
;
Vasculitis/therapy*
10.Retrospective Analysis of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in 88 Chinese Patients.
Chinese Medical Journal 2017;130(9):1062-1068
BACKGROUNDStevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening diseases with high mortality rates. This study was designed to analyze the pathogenic factors, clinical manifestations, complications, treatment, and prognosis of SJS/TEN and to explore the differences between surviving and deceased patients.
METHODSSJS/TEN patients admitted to Beijing Friendship Hospital from January 2006 to December 2015 were included in the study. Patients' data were retrospectively analyzed. Comparative studies were performed on the survival group and the deceased group, and Fisher's exact probability test was used for statistical analysis.
RESULTSAmong the 88 patients included, 40 (45.5%) were male with a mean age of 45 ± 18 years. Forty-eight (54.5%) had SJS, 34 (38.6%) had SJS/TEN, and 6 (6.8%) had TEN. Fifty-three (60.2%) cases were caused by medications, mainly antibiotics (n = 24) followed by traditional Chinese medicines (n = 7). Forty-two cases (47.7%) developed visceral damage. Eighty-two patients improved or recovered and were discharged from hospital, and six patients died. Comparative studies on the survival group and the deceased group showed that the presence of malignant tumor ( χ2 = 27.969,P < 0.001), connective tissue diseases ( χ2 = 9.187, P= 0.002), previous abnormal liver/kidney functions ( χ2 = 6.006, P= 0.014), heart rate >100 times/min ( χ2 = 6.347, P= 0.012), detached skin area >20% ( χ2 = 5.594, P= 0.018), concurrent mucosal involvement at the mouth, eyes, and external genitals ( χ2 = 4.945, P= 0.026), subsequent accompanying liver/kidney damage ( χ2 = 11.839, P= 0.001, and χ2 = 36.302,P < 0.001, respectively), and SCORTEN score >2 ( χ2 = 37.148,P < 0.001) increased the risk of death.
CONCLUSIONSSJS/TEN is mainly caused by medications, and nearly half of patients develop visceral damage. Multiple factors increase the mortality risk.
Adult ; Anti-Bacterial Agents ; therapeutic use ; Connective Tissue Diseases ; metabolism ; pathology ; Eye ; pathology ; Female ; Genitalia ; pathology ; Humans ; Kidney ; metabolism ; pathology ; Liver ; metabolism ; pathology ; Male ; Middle Aged ; Mouth ; pathology ; Retrospective Studies ; Skin ; metabolism ; pathology ; Stevens-Johnson Syndrome ; drug therapy ; metabolism ; pathology