The authors evaluated the efficacy of cromal in the treatment of allergic conjunctivitis. Method: 30 patients (28 males, 12 females) were assigned in two groups: group1:14 patients with seasonal allergic conjuntivitis; group2: 24 patients with vernal keratoconjuntivitis. In a double masked random design, the patients of each group were received cromal eye drops or NaCl 0.9%. Results: eyes treated with cromal eye drops in two groups showed an amelioration of the sign and symptoms of disease compared with eyes received only NaCl 0.9%. Conclusion: cromal seems to be effective in treatment of allergy.
Conjunctivitis, Allergic ; therapy ; therapeutics

Twenty-too patients were treated with Naaxia. Of these, 11 patients had vernal conjunctivitis and 8 patients had chronic allergic conjunctivitis. 19 patients(86.4%) achieved beneficial effect. The most frequent side effect was mild burning sensation after instillation and no systemic side effect was found.
Burns ; Conjunctivitis, Allergic* ; Humans ; Sensation

Chronic atopic conjunctivitis is essentially a perennial inflammatory reaction. There are a number of ways, both immunological and non-immunological, in which micro-organisms can cause degranulation of the mast cells which leads to an exacerbation of the atopic reaction. As in such cases often only a small number of bacteria are isolated, their potential pathogenic role in such exacerbations can easily be overlooked. Therefore, in cases of an unexplained inreased inflammatory reaction in chronic atopic conjunctivitis, it is advisable to institute a short term antibiotic regimen, preferable with a broad spectrum antibiotic such as Gentamicin.
Bacteria ; Conjunctivitis, Allergic ; Gentamicins ; Hypersensitivity* ; Mast Cells

Chronic atopic conjunctivitis is essentially a perennial inflammatory reaction. There are a number of ways, both immunological and non-immunological, in which micro-organisms can cause degranulation of the mast cells which leads to an exacerbation of the atopic reaction. As in such cases often only a small number of bacteria are isolated, their potential pathogenic role in such exacerbations can easily be overlooked. Therefore, in cases of an unexplained inreased inflammatory reaction in chronic atopic conjunctivitis, it is advisable to institute a short term antibiotic regimen, preferable with a broad spectrum antibiotic such as Gentamicin.
Bacteria ; Conjunctivitis, Allergic ; Gentamicins ; Hypersensitivity* ; Mast Cells

PURPOSE: To evaluate tear eosinophil cationic protein (ECP) as a severity marker for atopic keratoconjunctivitis (AKC) and seasonal/perennial allergic conjunctivitis (SAC/PAC). METHODS: Tear ECP levels were measured by chemiluminescent immunometric assay in 7 eyes of 7 patients with AKC, 13 eyes of 13 patients with SAC/PAC, and 10 eyes of 10 healthy control subjects. All AKC and SAC/PAC patients underwent conjunctival injection and papillary formation grading. Tear ECP levels were investigated with reference to the clinical parameters of allergic conjunctivitis (papillary formation and conjunctival injection scoring). RESULTS: Tear ECP levels in patients with AKC were significantly higher than those in patients with SAC/PAC and in control subjects (p = 0.012 and p = 0.003, respectively). The number of patients with papillary formation scores of 2-3 was significantly higher in the AKC group than in the SAC/PAC group (p = 0.016). The number of patients with conjunctival injection scores of 2-3 did not significantly differ between the AKC and SAC/PAC groups (p = 0.128). All AKC patients obtained papillary formation scores of 2-3, and tear ECP levels in patients with conjunctival injection scores of 2-3 were significantly higher than in patients with scores of 0-1 in the AKC group (p < 0.001). In the SAC/PAC group, tear ECP levels in patients with papillary formation scores of 2-3 were significantly higher than in patients with scores of 0-1 (p = 0.046). CONCLUSIONS: This study suggests that tear ECP was a useful marker to diagnose and assess the severity of disease in patients with AKC as well as SAC/PAC. It would be useful to monitor therapeutic outcome in allergic conjunctivitis.
Conjunctivitis, Allergic ; Eosinophil Cationic Protein* ; Humans ; Keratoconjunctivitis*

Levocabastine, a selective H1-receptor antagonist, has been evaluated in the management of allergic conjunctivitis and its efficacy was compared between the skin test positive and negative groups. A total of 20 patients who was clinically diagnosed as allergic conjunctivitis were processed for the skin test. According to the results of skin test, patients were divided into two groups; skin test positive (15) and negative (5). Livostin(levocabastine 0.5mg/ml) eye drops were topically instilled 2 times per day for 1 week. Both subjective and objective findings were assessed by a 4-point scase (0=none, 1=mild, 2=moderate, 3=severe). The parameters used for the examination of drug effectiveness were itching, tearing, chemosis, lid swelling and injection. 85.5% (17 put of 20) of the patients showed effects on the management of their symptoms and signs. No significant difference was observed in its effectiveness between skin test positive and negative groups. The results of present clinical trials suggest that Livostin eye drops may be an attractive therapeutic option for the management of allergic conjunctivitis.
Conjunctivitis, Allergic* ; Humans ; Ophthalmic Solutions* ; Pruritus ; Skin Tests

Giant papillae of the upper tarsal conjunctiva have been found in vernal conjunctivitis and, more recently, in giant papillary conjunctivitis in patients with contact lenses. Two patients who received cataract surgery were found to have unilateratgiant papillary conjunctivitis which were supposed to be induced by protruded suture end(10-0 prolene). Eosinophil was not found in the conjunctival scraping from giant papillae of the patients. Giant papillae of tarsal conjunctiva were resolved by removal of protruded sutures.
Cataract* ; Conjunctiva ; Conjunctivitis ; Conjunctivitis, Allergic* ; Contact Lenses ; Eosinophils ; Humans ; Polypropylenes* ; Sutures*

BACKGROUND: The worldwide prevalence of obesity and allergic diseases has increased. We aimed to explore the relation of overweight to asthma, atopic dermatitis, allergic rhinitis and conjunctivitis in a sample of Korean adolescents. METHODS: We investigated the prevalence of symptoms of asthma and other allergic diseases by using a modified International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire. The survey was conducted among 1,499 high school students in 3 regions of Korea. RESULTS: The lifetime prevalence of wheezing (21.2% vs. 15.7%, P = 0.04), the 12 months-prevalence of wheezing (4.5% vs. 2.0%, P = 0.04), exercise induced wheezing (13.8% vs. 9.3%, P = 0.04), treatment of asthma (3.3% vs. 1.1%, P = 0.01) and the prevalence of symptoms of allergic rhinitis (11.0% vs. 5.1%, P = 0.001) were signifi cantly higher in overweight boys than normal weight boys, but not in girls. However, there were no signifi cant differences of the prevalence of symptoms and past history of atopic dermatitis and allergic conjunctivitis between overweight and normal weight groups. In boys, overweight increased the risk of the lifetime prevalence of wheezing (OR 1.54, 95% CI: 1.05-2.24) and 12 months-prevalence of exercise induced wheezing (OR 1.64, 95% CI: 1.05-2.55) after adjusting for confounding variables. CONCLUSION: Overweight could be a risk factor for the development of symptoms of asthma and allergic rhinitis in adolescent boys, whereas it was not a signifi cant risk factor for allergic diseases in girls.
Adolescent ; Asthma ; Confounding Factors (Epidemiology) ; Conjunctivitis ; Conjunctivitis, Allergic ; Dermatitis, Atopic ; Humans ; Hypersensitivity ; Korea ; Obesity ; Overweight ; Prevalence ; Respiratory Sounds ; Rhinitis ; Rhinitis, Allergic, Perennial ; Risk Factors

PURPOSE: We investigated the prevalence of allergic diseases in preschoolers and children attending elementary, middle and high schools in Seogwipo city, Jeju, South Korea. METHODS: A cross-sectional survey in November 2008 was conducted, using questionnaires, translated in Korean, from the International Study of Asthma and Allergies in Childhood group. All the attendees, 29,606, in 136 nurseries and kindergartens, 47 elementary schools, 15 middle schools and 10 high schools in Seogwipo city were surveyed in this study. RESULTS: Of the 25,312 (85.5%) questionnaires retrieved, 25,024 were appropriately completed and analyzed. For asthma, the prevalence of "wheeze, last 12 months" was 15.4% for the preschool children, 6.4% for the elementary school students, 5.3% for the middle school students and 5.8% for the high school students. The prevalence of "allergic rhinitis, last 12 months" was 23.9%, 30.0%, 31.4% and 34.2%, respectively. The prevalence of "atopic dermatitis, last 12 months" was 19.0%, 17.4%, 12.3% and 11.4%, respectively. The prevalence of "allergic conjunctivitis, last 12 months" was 8.5%, 12.3%, 20.3% and 23.4%, respectively. The prevalence of "food allergy, last 12 months" was 5.4%, 4.2%, 4.2% and 5.1%, respectively. The prevalence of "drug allergy, last 12 months" was 0.7%, 0.3%, 0.6%, and 0.8% for each group. CONCLUSION: In Seogwipo city, the prevalence of asthma and atopic dermatitis decreases with age. However, allergic rhinitis and allergic conjunctivitis are increasing by age. The prevalence of food allergy and drug allergy showed no difference by age.
Asthma ; Child ; Child, Preschool ; Conjunctivitis ; Conjunctivitis, Allergic ; Cross-Sectional Studies ; Dermatitis ; Dermatitis, Atopic ; Drug Hypersensitivity ; Food Hypersensitivity ; Humans ; Hypersensitivity ; Nurseries ; Prevalence ; Surveys and Questionnaires ; Rhinitis ; Rhinitis, Allergic, Perennial

PURPOSE: This study is to estimate the prevalence of allergic disease for the entire inhabitants living in Udo Isle, one of the islands of Jeju. METHODS: The complete enumeration using International Study of Asthma and Allergies in Childhood group was applied to the 1,090 people residing in the Isle. This survey was performed for 2 months from June to July, 2012. For children, their parents' responses were collected, and for adults, their self-reports and interview were performed simultaneously. Of the 1,003 questionnaires (92.0%) were collected, 925 questionnaires were finally analyzed, excluding those of insufficient responses for questionnaires and inhabitants residing in Udo Isle less than one year. RESULTS: For asthma, the prevalence of "wheeze, last 12 months" was 6.6%. The prevalence of "allergic rhinitis, last 12 months" was 17.9%. The prevalence of "itchy eczema, last 12 months" was 8.1%. The prevalence of "allergic conjunctivitis, last 12 months" was 8.1%. The prevalence of "food allergy, last 12 months" was 2.3%. The prevalence of "drug allergy, last 12 months" was 0.8%. CONCLUSION: The inhabitants of Udo Isle had lower prevalence of atopic dermatitis than that of in the entire Jeju Island. However, compared with other regions, it showed higher prevalence, and it tended to be decreased with aging. The prevalence of asthma, allergic rhinitis, allergic conjunctivitis, food allergy and drug allergy, presented no difference by age.
Adult ; Aging ; Asthma ; Child ; Conjunctivitis ; Conjunctivitis, Allergic ; Dermatitis, Atopic ; Drug Hypersensitivity ; Eczema ; Food Hypersensitivity ; Humans ; Hypersensitivity ; Islands ; Prevalence ; Rhinitis ; Rhinitis, Allergic, Perennial ; Surveys and Questionnaires