1.Comparison study of two diagnostic and grading systems for conjunctivochalasis.
Xing-ru ZHANG ; Hai-dong ZOU ; Qing-song LI ; Huan-ming ZHOU ; Bin LIU ; Zhu-mei HAN ; Min-hong XIANG ; Zheng-yong ZHANG ; Han-min WANG
Chinese Medical Journal 2013;126(16):3118-3123
BACKGROUNDDifferent diagnostic and grading systems of conjunctivochalasis have resulted in apparent disparity between the prevalence rates of recent population-based studies. This study aimed to investigate the disparity between 4-level system cited from Meller and Tseng in 1998 (abbreviated here as Meller's system) and 5-level system modified from Meller's system cited from Zhang and associates (abbreviated here as Zhang's system) regarding the diagnosis and the patients' preferences for the treatment of conjunctivochalasis in the general population.
METHODSA total of 546 senile residents living in the Guiyangyuan community of Shanghai, China, participated in the study. The diagnostic criteria for conjunctivochalasis were based on two diagnostic grading systems: Meller's system and Zhang's system, which was modified from Meller's system. The participants' preference regarding medical treatment for conjunctivochalasis was determined according to the response to a question. One year later, a follow-up interview determines whether the patient had undergone surgery for conjunctivochalasis.
RESULTSWith Meller's system, 398 participants were confirmed as having conjunctivochalasis, and the prevalence rate was 72.89%. According to Zhang's system, only 213 participants were diagnosed as having conjunctivochalasis, and the prevalence rate was 39.01%. A total of 109 eyes underwent medical treatment or surgery for conjunctivochalasis in the following year, including eight eyes that were diagnosed as grade II and 101 eyes that were diagnosed as grade III according to Meller's system and five eyes that were diagnosed as grade I, 55 eyes that were diagnosed as grade II, 31 eyes that were diagnosed as grade III, and 18 eyes that were diagnosed as grade IV according to Zhang' system.
CONCLUSIONDiagnoses of conjunctivochalasis using Zhang's system are more consistent with patient requests and the medical treatment strategies used than diagnoses made using Meller's system.
Aged ; Aged, 80 and over ; Conjunctival Diseases ; diagnosis ; epidemiology ; pathology ; Female ; Humans ; Male ; Middle Aged
2.Primary Localized Amyloidosis of Bulbar Conjunctiva and Cornea.
Beak Ran SONG ; Yung Ki KIM ; Joong Ha YOO ; Young Chae CHU
Journal of the Korean Ophthalmological Society 1993;34(4):352-356
The major forms of amyloidosis affecting the eye are primary systemic and localized amyloidosis. Primary Amyloidosis localized to the conjuctiva is relatively rare, especially involved to bulbar conjunctiva and corn eo scleral limbus and is consiccered to be in the differential diagnosis of other conjunctival diseases. We diagnosed a amyloidosis in which the biopsy from the superior bulbar conjunctiva and superior cornea of the left eye of 68-year-old woman showed histopathologic findings of amyloidosis. There were no evidences of amyloid deposit except conJuntiva and cornea on physical and other systemic examination, including immunelectrophoresis, and cornea on physical and other systemic examination, including immunelectrophoresis, and no evidences of underlying disease that can cause amyloidosis. So we concluded that it was primary localized amyloidosis of bulbar conjunctiva and cotnea.
Aged
;
Amyloidosis*
;
Biopsy
;
Conjunctiva*
;
Conjunctival Diseases
;
Cornea*
;
Diagnosis, Differential
;
Female
;
Humans
;
Plaque, Amyloid
;
Zea mays
3.Primary Localized Amyloidosis of Bulbar Conjunctiva and Cornea.
Beak Ran SONG ; Yung Ki KIM ; Joong Ha YOO ; Young Chae CHU
Journal of the Korean Ophthalmological Society 1993;34(4):352-356
The major forms of amyloidosis affecting the eye are primary systemic and localized amyloidosis. Primary Amyloidosis localized to the conjuctiva is relatively rare, especially involved to bulbar conjunctiva and corn eo scleral limbus and is consiccered to be in the differential diagnosis of other conjunctival diseases. We diagnosed a amyloidosis in which the biopsy from the superior bulbar conjunctiva and superior cornea of the left eye of 68-year-old woman showed histopathologic findings of amyloidosis. There were no evidences of amyloid deposit except conJuntiva and cornea on physical and other systemic examination, including immunelectrophoresis, and cornea on physical and other systemic examination, including immunelectrophoresis, and no evidences of underlying disease that can cause amyloidosis. So we concluded that it was primary localized amyloidosis of bulbar conjunctiva and cotnea.
Aged
;
Amyloidosis*
;
Biopsy
;
Conjunctiva*
;
Conjunctival Diseases
;
Cornea*
;
Diagnosis, Differential
;
Female
;
Humans
;
Plaque, Amyloid
;
Zea mays
4.Kimura Disease Involving a Caruncle.
Woo Jin KIM ; Myoung Ja CHUNG ; In Cheon YOU
Korean Journal of Ophthalmology 2013;27(2):137-140
A 35-year-old woman presented with history of a painless, slow-growing nodule in a left eye caruncle over the last 2 months. The visual acuity was 20 / 20 and the ocular movements were in the normal range. The venereal disease research laboratory test, erythrocyte sedimentation rate, serum angiotensin converting enzyme level, and chest radiograph were all normal. An excisional biopsy was done to confirm the diagnosis. A 1.3 x 0.5 x 0.3 cm sized nodule was extracted and sent for histopathologic examination. Hematoxylin-eosin staining showed follicular hyperplasia with perifollicular fibrosis, an eosinophil infiltrate, and proliferation of capillary vessels. The capillaries were lined by normal-appearing, flat, spindle-shaped endothelial cells. On the basis of these histopathologic findings, the diagnosis of Kimura disease in a caruncle was established. This is the first report describing Kimura disease localized to a caruncle. Kimura disease should be suspected and included in the differential diagnosis of a caruncular mass lesion.
Adult
;
Angiolymphoid Hyperplasia with Eosinophilia/*diagnosis
;
Asian Continental Ancestry Group
;
Conjunctiva/*pathology
;
Conjunctival Diseases/*diagnosis
;
Diagnosis, Differential
;
Female
;
Humans
5.Kimura Disease Involving a Caruncle.
Woo Jin KIM ; Myoung Ja CHUNG ; In Cheon YOU
Korean Journal of Ophthalmology 2013;27(2):137-140
A 35-year-old woman presented with history of a painless, slow-growing nodule in a left eye caruncle over the last 2 months. The visual acuity was 20 / 20 and the ocular movements were in the normal range. The venereal disease research laboratory test, erythrocyte sedimentation rate, serum angiotensin converting enzyme level, and chest radiograph were all normal. An excisional biopsy was done to confirm the diagnosis. A 1.3 x 0.5 x 0.3 cm sized nodule was extracted and sent for histopathologic examination. Hematoxylin-eosin staining showed follicular hyperplasia with perifollicular fibrosis, an eosinophil infiltrate, and proliferation of capillary vessels. The capillaries were lined by normal-appearing, flat, spindle-shaped endothelial cells. On the basis of these histopathologic findings, the diagnosis of Kimura disease in a caruncle was established. This is the first report describing Kimura disease localized to a caruncle. Kimura disease should be suspected and included in the differential diagnosis of a caruncular mass lesion.
Adult
;
Angiolymphoid Hyperplasia with Eosinophilia/*diagnosis
;
Asian Continental Ancestry Group
;
Conjunctiva/*pathology
;
Conjunctival Diseases/*diagnosis
;
Diagnosis, Differential
;
Female
;
Humans
6.Seborrheic Keratosis of the Conjunctiva: A Case Report.
Ji Hyun KIM ; Hyoung Won BAE ; Kwang Kil LEE ; Tae Im KIM ; Eung Kweon KIM
Korean Journal of Ophthalmology 2009;23(4):306-308
Seborrheic keratosis is a benign epithelial neoplasia that occurs mainly in the skin of the eyelids and face. We describe a case of seborrheic keratosis of the conjunctiva confirmed by histopathology. A 72-year-old man presented with a recurrent conjunctival mass involving the nasal side of his right eye. Clinically, a diagnosis of conjunctival papilloma was made, and a mass excision was performed. The histopathological analysis evidenced a conjunctival-covering epithelium with papillomatous changes and irregular acanthosis, at the expense of a proliferation of basaloid cells. In addition, the lesion exhibited multiple pseudohorn cysts containing keratin. With the above findings, a diagnosis of conjunctival seborrheic keratosis was established. The occurrence of seborrheic keratosis on the conjunctiva is rare. In this case, seborrheic keratosis was confirmed by pathologic report despite its similar appearance with papilloma. Seborrheic keratosis should be considered in the differential diagnosis of conjunctival lesions.
Aged
;
Conjunctival Diseases/*diagnosis/surgery
;
Diagnosis, Differential
;
Follow-Up Studies
;
Humans
;
Keratosis, Seborrheic/*diagnosis/surgery
;
Male
;
Microscopy, Acoustic
;
Ophthalmologic Surgical Procedures/methods
7.Conjunctival Hypertrophic Scar Following Cryotherapy for Retinopathy of Prematurity.
In Jeong LYU ; Ho Seok SA ; Kyung In WOO ; Yoon Duck KIM
Korean Journal of Ophthalmology 2013;27(1):55-57
A 6-year-old boy was referred to our hospital with symblepharon and lateral canthal deformity in both eyes, which developed 6 years ago. The patient was born at 27 weeks gestation. He had received cryotherapy for retinopathy of prematurity. One month after cryotherapy, he developed a conjunctival scar with symblepharon in both eyes and underwent symblepharon lysis at another hospital 5 years prior. Ocular examination revealed an extensive conjunctival hypertrophic scar with symblepharon and limitation of extraocular movements. An excisional biopsy, lateral canthoplasty, and symblepharon lysis with conjunctival autograft from the contralateral eye were performed in the left eye. Histopathologic examination revealed diffuse proliferation and infiltration of collagenous tissue.
Biopsy
;
Child
;
Cicatrix, Hypertrophic/diagnosis/*etiology
;
Conjunctiva/pathology
;
Conjunctival Diseases/diagnosis/*etiology
;
Cryotherapy/*adverse effects
;
Diagnosis, Differential
;
Follow-Up Studies
;
Humans
;
Male
;
Retinopathy of Prematurity/*therapy
9.Conjunctival langerhans cell histiocytosis: a case report.
Chinese Medical Sciences Journal 2015;30(1):63-64
Langerhans cell histiocytosis (LCH) is a rare disease, mainly involving the bone, skin, lung, liver, spleen, and skin.1 The heterogenenous nature of LCH makes it difficult to diagnose. Not only do the involved organs vary from case to case, but also its natural history. Herein, we describe a rare case of conjuctival LCH in an Asian woman.
Conjunctival Diseases
;
diagnosis
;
drug therapy
;
Cyclophosphamide
;
therapeutic use
;
Cyclosporine
;
therapeutic use
;
Female
;
Histiocytosis, Langerhans-Cell
;
diagnosis
;
drug therapy
;
Humans
;
Middle Aged
;
Prednisone
;
therapeutic use
10.Research on slit lamp bio-microscope image analysis system.
Xin-ming ZHANG ; Lan-sun SHEN ; Bo SHEN ; Jie ZHANG ; Xin-wei WANG
Chinese Journal of Medical Instrumentation 2002;26(1):10-13
Slit lamp bio-microscope image analysis system can provide objective and quantitative diagnosis evidences for ophthalmologists and make available efficient storing, management and intercourse of sufferer information and diagnosis results. In this paper, the system is discussed on its devices, software structure, analysis process and algorithm.
Algorithms
;
Conjunctival Diseases
;
diagnosis
;
Corneal Diseases
;
diagnosis
;
Diagnostic Techniques, Ophthalmological
;
instrumentation
;
Eye Diseases
;
diagnosis
;
Humans
;
Image Enhancement
;
instrumentation
;
methods
;
Image Interpretation, Computer-Assisted
;
instrumentation
;
methods
;
Information Storage and Retrieval
;
methods
;
Ophthalmoscopy
;
methods
;
Software