Objective To study the feasibility of the self-made negative pressure drainage device used for postoperative drainage of thyroid surgery. Methods To sum up 98 cases experiences of device utilization, we analyzed the manufacturing technology and the key points. Results All cases acquired success, of which one case gained 750 ml draining liquid of maximum daily, the other 97 cases had 15 -160 ml/d draining liquid, 33 ml/d average, drainage time 24-72 h, of which>36 h 53cases,>36-48 h 42cases, >48 h and ≤72 h 3cases, and medial 34 h. Conclusions Self-made negative pressure drainage device is convenient, simple, inexpensive and reliable production, which is worth of clinical promotion.