1.6 Classes of Low-dosage of Antihypertensive Agents for Essential Hypertension
Congxiao HUA ; Lu HUA ; Na LI ; Li WANG ; Huimin PANG ; Guanghua MING ; Yan HUANG ; Xiaoru CHENG ; Hong LIU ; Ying WU ; Li XU ; Jian KANG ; Zhimin XU ; Yishi LI
China Pharmacy 2007;0(35):-
OBJECTIVE:To provide references for clinicians in the choice of antihypertensive drugs.METHODS:The antihypertensive efficacy 6 classes(or 15 kinds) of antihypertensive drugs in a monotherapy in the treatment of 370 patients with essential hypertension(EH) were compared.RESULTS:The blood pressure was effectively lowered by all of the antihypertensive drugs except doxazosin,and doxazosin and torasemide showed inferior efficacy in the reduction of diastolic blood pressure(DBP).CONCLUSION:Calcium antagonists with prolonged action,angiotensin converting enzyme inhibitor(ACEI),angiotens-in receptor antagonist,and the monotherapy of Terazosin or Indapamide can all effectively bring down the blood pressure.It is suggested that low-dose doxazosin and torasemide should not be used alone in treating essential hypertension.
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