1.Fibrous dysplasia: some opinions of the epidemiological features and the imaging specificity
Journal of Vietnamese Medicine 1998;230(11):150-0
Cross sectional retrospective study of 20 cases of Fibrous dysplasia confirmed by pathological result at Muculoskeletal Pathology Ward, Traumatologic and Orthopedic Center Hå ChÝ Minh City we noted a female predominance with M/F ratio = 13/7; ages group from 8 to 58 year old average age 24 year old. Polyostotic F.D exists only in 5 cases while the rest 15 cases are Monostotic F.D Tibia and femur are the most affected bones. Depend on the sites of lesion, we have 4 main patterns of bone lesion: 1. Pure lytic lesion. 2. Ground glass lesion. 3. Sclerotic lesion. 4. Complex lesion. From the determining factors as sex, age, sites of lesions, pattern of bone lesions, we try to find some criteria for the diagnosis of FD disease in Vietnamese patients.
Fibrous Dysplasia of Bone
;
Diagnosis
;
epidemiology
2.Fibrous dysplasia of bone - some epidemiological opinions on the lesion characteristics in conventional X-ray film
Journal of Practical Medicine 2002;437(12):32-35
A retrospective and cross sectional study was carried out in 23 cases of Fibrous dysplasia (FD) of bone diagnosed in Musculoskeletal Pathology ward, Traumatic & Orthopedic Center, HCMC, we noticed that Male/female ratio = 1:2.2, the peak age is the 2nd decade Monostolic FD: Pylyostotic FD=12:11. In monostotic FD, the lower limb is most affected (83.3%) in which tibia is the most common bone involved, while polyostotic FD is most encountered in the femur and pelvis. The most common X ray finding is the bone expansion lesion (79.6%), followed by mixtelytic and sclerotic osseous lesions, ground glass aspect (39%). The zone of transition is narrow (77.2%) and sclerotic margin (63.6%) are other common findings. "Crook shepherd" deformity is classic sign in femoral FD.
Fibrous Dysplasia of Bone
;
Diagnosis
;
epidemiology
3.Evaluation of prevention effectiveness of intracranial hemorrhage with vitamin K injection for newborns
Khanh Cong Nguyen ; Thang Van Nguyen
Journal of Medical Research 2007;49(3):47-53
Background: Intracranial hemorrhage (lCH) is a common disease with high rate of mortality and neurological sequel. Objectives:to estimate preventive effectiveness of intracranial hemorrhage by vitamin K1 and K3 for newborns just after birth". Subjects and methods: An epidemiological, randomized control study with intervention was conducted. The study included all children under 3 months with and without ICH during period 1/1/2000 -30/6/2004 living in Hatay province. Among them all the newborns during period 1/6/2002 - 30/6/2004 were injected either 1 mg vitamin K1 or K3. Results: Children injected with vitamin K in the intervention period were followed up in three months and evaluated by a united process. Effects of intervention were calculated by preventive value. 62.057/82069 newborns were injected vitamin K1 or Vitamin K3 (25.725 newborns were injected Vitamin K1; 36.332 newborns were injected vitamin K3). Single dose 1M reduced the rate of ICH in infants: The morbidity changed from 3.3\ufffd?to 0.82\ufffd? the prevention value was 96%. There were no complications and side effects of vitamin K injections reported. Conclusions: Injection of vitamin K1 and K3 have similar preventive effectiveness. Vitamin K injection 1M with recommended dose was safe for newborns.\r\n', u' \r\n', u'\r\n', u'
Intracranial Hemorrhages
;
Vitamin K Deficiency
4.The relationship between genetic factors and plasma lipids in Vietnamese living in rural areas
Thu Nguyet Nghiem ; Anh Do Van Nguyen ; Khan Cong Nguyen ; Mai Thi Tuyet Ta ; Chuyen Van Nguyen
Journal of Preventive Medicine 2008;0(3):13-17
Background: Plasma lipids are affected not only by dietary intake and life style but also by genetic factor. Objective: To discover the relationship between plasma lipids and the presence of LPL S447X and PAF-AH V279F in the bodies of rural Vietnamese population. Subject and Method: One hundred and ninety three subjects were randomly selected from rural areas in Ho Chi Minh city. The presence of LPL S447X and PAF-AHV279F polymorphism was determined using an Invader assay, and the plasma lipid levels were measured by an enzymatic method. A profile regarding the dietary intake was also made for each subject. Result and Conclusion: The frequency of LPL 447SX/XX (12.2%) polymorphism, PAF-AH Val279Phe mutation allele frequency (5.4%) in the Vietnamese was closely similar to that of other Asian populations. LPL447X polymorphism was found to be significantly associated with a higher HDL-C level in comparison to LPL 447S. LPL S447X affects plasma HDL-C and TG concentration in Vietnamese rural population.
Genetic factors
;
plasma lipids
;
rural area
5.Indication and characteristics of lapasoscopy tranperitoneal ureterolithotomy
Chien Van Bui ; Binh Cong Nguyen ; Chuyen Le Vu ; Kien Van Vu
Journal of Medical and Pharmaceutical Information 2001;6(6):32-36
Background: Most abdominal surgery can be done by laparoscopic method. For urologic surgery, laparoscopic surgery is used to cut the kidney, prostate, seminal vesicles and get urinary stones, including the ureter stones.\r\n', u'Objectives: Contribute to improving treatment effects ureter stones by lapasoscopy tranperitoneal ureterolithotomy\r\n', u'Subjects and method: Laparoscopic transperitoneal ureterolithotomy was attempted in 90 patients (50 men and 34 women) with an age range of 22 \ufffd?75 years (mean 43.60+ 11.97 years). Learn characteristics of ureteral calculi (X-ray, ultrasound, urinary map vein) and surgical methods.\r\n', u'Results:The results showed that: Most ureterolith at L3 vertebral level (55.6%) and L4 (40.0%). The stone size ranged from 8 to 22mm (mean 13.87+ 3.25mm) and an average width 4 to 12mm (mean 6.96 + 1.82mm). Most cases of ureteral calculi with the situation fluid in the kidney level 2 (76.7%). The stone has impacted in the upper and mid ureter. Two 10-mm and one 5mm trocars were used. Most cases of stage 2 nasal. The mean operative time was 57.22 + 15.51 minutes (30-90 minutes). \r\n', u'Conclusion: The authors conclude that laparoscopic ureterolithotomy by the transperitoneal approach is a safe and reliable minimally invasive procedure. For large, hard, long-standing and impacted ureteric calculi, one laparoscopicureterolithotomy is an initial therapy\r\n', u'
Ureterostomy
;
Laparoscopy
6.Study of insulin resistance in hypertensive patients with impaired fasting glucose \r\n', u'\r\n', u'
Toan Canh Nguyen ; Thai Quoc Ngo ; Hieu Trung Luong ; Khoa Tran Anh Pham ; Son Van Nguyen ; Cong Duc Nguyen
Journal of Medical and Pharmaceutical Information 2005;0(12):22-24
Background: Hypertensive with impaired fasting glucose is the basic expression of metabolic syndrome. Objectives: To study the IR and the correlation between Fasting Plasma Insulin (FPI) and Fasting Plasma Glucose (FPG) concentration in hypertensive patients with Impaired Fasting Glucose (IFG). Subjects and method: The descriptive, cross-sectional study was carried out on 38 hypertensive patients with IFG (IFG group) and 30 hypertensive patients without IFG (control group). The data were collected and analyzed by SPSS 11.5 software. Results:The FPI and IR index in the IFG group were 14.6+/-5.2 micro mol/ml and 3. 94+/- l.40, respectively, higher than in the control group (9.6+/-4.2 micro mol/ml and 2.17+/-0.99/ respectively) with p<0.00l. There was a positive correlation between FPI and FPG systolic blood and diastolic blood pressure/ with correlation coefficients were 0.4/ 0.48 and 0.46/ respectively (p<0.00l). Conclusion: There was an increase of FPI and IR index in the hypertensive patients with IFG compared to those without IFG. \r\n', u'\r\n', u'
Insulin resistance
;
hypertensive patients
;
impaired fasting glucose.
7.Evaluate on epidemic supervision and propose solutions to protect healthy for soldiers and people in malaria epidemic area.
Ngo Van Ly ; Thuan Khanh Le ; Loc Ba Ly ; Doan Van Nguyen ; Sinh Cong Nguyen ; Tuan Dinh Trinh ; Duc Ai Quach ; Thao Duc Nguyen ; Thuc Duy Nguyen ; Binh Van Nguyen ; Thang Duc Do
Journal of Malaria and parasite diseases Control 2003;0(1):13-24
Background: Coordinating between soldiers and people bring significant results in protecting healthy for soldiers and people in malaria epidemic area.\r\n', u'Objectives: To evaluate epidemic supervision and propose solutions protecting healthy for soldiers and people in malaria epidemic area.\r\n', u'Subjects and methods: A retrospective cross sectional study was carried out on two provinces Binh Phuoc and Dak Lak\r\n', u'Results: there was 4 main disease types were fever, tuberculosis, diarrhea and malaria. Malaria at investigated times still accounted high rate comparing with general fever rate. Malaria risk contained in people living or working in forest and mountain field; free emigrants; armed forces and border guard. These subjects needed to improve regularly protection from malaria. Communication of health education is one of important method to prevent and control malaria.\r\n', u'Conclusion: It is necessary to implement strong methods (such as providing insecticide treated bed nets, indoor residual spray) to prevent and control malaria. \r\n', u'
Epidemic supervision
;
healthy
;
soldier
;
malaria epidemic area.
8.Evaluating clinical experience from a case of hepatocellular carcinoma with combinated therapy of transarterial chemoembolization and percutaneousethanol injection afterward emerging metatasis caused by fine needle aspiration cytology
Long Cong Nguyen ; Truong Xuan Bui ; Thong Minh Pham ; Ho Thi Thu Pham ; Hung Quoc Nghiem ; Phuong Minh Tran ; Long Van Dao ; Trach Khanh Nguyen
Journal of Medical Research 2007;47(2):69-73
Background: Hepatocellular carcinoma (HCC) is the most common primary hepatic tumor and one of the most common cancers worldwide. HCC is a primary malignancy of hepatocellular origin. Objectives:The aim of study is to combinate therapy of transarterial chemoembolization and percutaneousethanol injection afterward emerging metatasis caused by fine needle aspiration cytology. Subjects and method: A 50 years old male patient with hepatocellular carcinoma having a diameter of tumor more than 5 cm was treated by combination of transarterial chemoembolization and percutaneous ethanol injection from December 2000. Results & Conclusion: Results of study showed that: Transarterial chemoembolization and percutaneous ethanol injection are the two of non-surgical methods for treatment of hepatocellular carcinoma which are most commonly available in applied clinical activities at present. Up to now, the patient's life expectancy after therapy is more than 6 years that means the result of treatment is very good. However, the emerging metatasis into the anterior-right-Iower chest wall that was caused by fine needle aspiration cytology should be reviewed for further evaluating clinical experience, especially in cases with quite clear imaging features of untrasonography and significantly elevated AFP level higher than 200 ng/rnl.
Carcinoma
;
Hepatocellular/ pathology
;
therapy
9.Removal of Manganese and Copper from Aqueous Solution by Yeast Papiliotrema huenov
Phu Nguyen VAN ; Hai Thi Hong TRUONG ; Tuan Anh PHAM ; Tuan Le CONG ; Tien LE ; Kim Cuc Thi NGUYEN
Mycobiology 2021;49(5):507-520
Papiliotrema huenov was previously reported to be highly tolerant of a range of extremely toxic heavy metals. This study aimed to identify the potential of P. huenov to remove manganese and copper from aqueous solution. Physical conditions which affect removal of Mn(II) and Cu(II) were determined. Optimal temperature for adsorption of both metal ions was 30°C, and optimal pH for maximum uptake of Mn(II) and Cu(II) were 5 and 6, respectively. Under these conditions, living cells of P. huenov accumulated up to 75.58% of 110 mg/ L Mn(II) and 70.5% of 128 mg/L Cu(II) over 120 h, whereas, the removal efficiency of metal ions by dead cells over 1 h was 60.3% and 56.5%, respectively. These results indicate that living cells are more effective than dead biomass for bioremediation, but that greater time is required. The experimental data extends the potential use of P. huenov in biosorption and bioaccumulation of toxic heavy metals to copper and manganese, two of the most common industrial contaminants.
10.Physiological intracytoplasmic sperm injection does not improve the quality of embryos: A cross-sectional investigation on sibling oocytes
Minh Tam LE ; Hiep Tuyet Thi NGUYEN ; Trung VAN NGUYEN ; Thai Thanh Thi NGUYEN ; Hong Nhan Thi DANG ; Thuan Cong DANG ; Quoc Huy Vu NGUYEN
Clinical and Experimental Reproductive Medicine 2023;50(2):123-131
Objective:
This study aimed to compare the efficacy of physiological intracytoplasmic sperm injection (PICSI) and intracytoplasmic sperm injection (ICSI) in terms of the fertilization rate and embryo quality using sibling oocyte cycles.
Methods:
This prospective, cross-sectional study collected data from 76 couples who underwent their first cycle at the Hue Center for Reproductive Endocrinology and Infertility, Vietnam, between May 2019 and November 2021. The inclusion criteria were cycles with at least eight oocytes and a sperm concentration of 5×106/mL. Sperm parameters, sperm DNA fragmentation (SDF), fertilization, and the quality of cleavage-stage embryos on day 2 and blastocysts on day 5 were examined.
Results:
From 76 ICSI cycles, 1,196 metaphase II (MII) oocytes were retrieved, half of which were randomly allocated to either the PICSI (n=592) or ICSI (n=604) treatment group. The results showed no significant difference between the two groups in terms of fertilization (72.80% vs. 75.33%, p=0.32), day 2 cleavage rate (95.13% vs. 96.04%, p=0.51), blastulation rate (52.68% vs. 57.89%), and high-quality blastocyst rate (26.10% vs. 31.13%, p=0.13). However, in cases where SDF was low, 59 cycles consisting of 913 MII oocytes produced a considerably higher blastulation rate with PICSI than with ICSI (50.49% vs. 35.65%, p=0.00). There were no significant differences between the pregnancy outcomes of the PICSI and ICSI embryo groups following embryo transfer.
Conclusion
Using variable sperm quality provided no benefit for PICSI versus ICSI in terms of embryo outcomes. When SDF is low, PICSI appears to be able to produce more blastocysts.