1.A Case of Leiomyoma in the Common Bile Duct.
Ja Chung GOO ; Mi Yeoun YI ; Won Joong JEON ; Jeong Chul SEO ; Hee Bock CHAE ; Seon Mee PARK ; Sei Jin YOUN ; Seok Hyoung KIM ; Jae Woon CHOI
The Korean Journal of Gastroenterology 2006;47(1):77-81
Leiomyomas, originating in the bile duct, are very rare, and only few cases have been reported in the literature. We experienced a case of leiomyoma of the distal common bile duct, mimicking bile duct cancer. A 39-year-old woman presented with intermittent jaundice and general weakness for three months. Clinical profiles showed obstructive jaundice, and the abdominal computed tomography and cholangiography revealed diffuse bile duct dilatation with distal common bile duct stricture. A pylorus-preserving pancreaticoduodenectomy was performed and the pathologic specimen disclosed leiomyoma of the common bile duct accompanying severe fibrosis. This is the first case of leiomyoma in the bile duct reported in Korea.
Adult
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Common Bile Duct Neoplasms/*diagnosis/pathology/surgery
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Female
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Humans
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Leiomyoma/*diagnosis/pathology/surgery
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Pancreaticoduodenectomy
2.A Case of Small Cell Neuroendocrine Tumor Occurring at Hilar Bile Duct.
Bum Chul KIM ; Tae Jun SONG ; Hyuk LEE ; Mee JOO ; Won Ki BAE ; Nam Hoon KIM ; Kyung Ah KIM ; June Sung LEE
The Korean Journal of Gastroenterology 2013;62(5):301-305
Neuroendocrine tumors of the extrahepatic biliary tree are extremely rare malignancies accounting for 0.2-2.0% of all gastrointestinal carcinoid tumors. Neuroendocrine tumors obstructing the biliary tree are extremely difficult to diagnose preoperatively and nearly impossible to differentiate from cholangiocarcinoma. Statistically, the most common anatomic location in the biliary tree is the common bile duct, followed by the perihilar region. Herein, we present a case of a small cell neuroendocrine carcinoma of the hilum in a 79-year-old man following laparotomy. To our knowledge, this is the first case of small cell type neuroendocrine carcinoma of hilar bile duct reported in Korea.
Aged
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Bile Duct Neoplasms/*diagnosis/pathology/surgery
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Cholangiopancreatography, Endoscopic Retrograde
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Diagnosis, Differential
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Hepatic Duct, Common/pathology
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Humans
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Male
;
Neuroendocrine Tumors/*diagnosis/pathology/surgery
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Tomography, X-Ray Computed
3.Prognostic implication of common bile duct infiltration in adenocarcinoma of the ampulla of Vater after pancreaticoduodenectomy.
Tie-cheng WU ; Yong-fu SHAO ; Yi SHAN ; Jian-xiong WU ; Dong-bing ZHAO ; Li-bin XU ; Ping ZHAO
Chinese Journal of Oncology 2008;30(10):775-778
OBJECTIVETo investigate the prognostic implication of common bile duct infiltration in the adenocarcinoma of the ampulla of Vater after panreaticoduodenectomy.
METHODSA retrospective study was conducted on clinical manifestation, pathological behavior and survival data in 102 patients with Vater's ampulla adenocarcinoma, who underwent pancreaticoduodenectomy from Jan 1980 to Dec 2003. The result of patients with the common bile duct infiltration were compared with that of those without.
RESULTSThere were 42 cases in stage I (41.2%), 32 in stage II (31.3%), 27 in stage III (26.5%), and 1 in stage IV (1.0%). As for T stage: 9 cases in stage T1 (8.8%), 40 in T2 (39.2%), 25 in T3 (24.5%), and 28 in T4 (27.5%). As regarding to N stage: 76 cases in stage N0 (74.5%) and 26 in N1 (25.5%). Of these 102 cases, microscopic infiltration in the common bile duct (25.0%) was identified in 26 cases. A significant difference was observed between the patients with bile duct infiltration and those without, in the proportion of pancreatic medullae infiltration: 84.6% (infiltration group) versus 34.2% (non-infiltration group, P < 0.001). Twenty-five cases (24.5%) had recurrence and/or metastases postoperatively, with a median survival of 20 months (range, 2 to 93 months). The overall median survival of the whole group was 46.0 months (2 approximately 192 months), with a significant difference between the common bile duct infiltration group (36 months) and the non-infiltration group (49 months, P = 0.0061). The median non-recurrence survival of the whole group was 43 months (2 approximately 192 months), and a significant difference was observed between the common bile duct infiltration group (35 months) and non-infiltration group (47 months, P = 0.0002).
CONCLUSIONIf the adenocarcinoma of the Vater's ampulla infiltrated the common bile duct, the invasion to the pancreatic medulla is likely developed, and usually with a poor non-recurrence and overall survival. Therefore, postoperative chemotherapy/radiotherapy is suggested.
Adenocarcinoma ; diagnosis ; pathology ; surgery ; Adult ; Aged ; Ampulla of Vater ; Common Bile Duct ; pathology ; Common Bile Duct Neoplasms ; diagnosis ; pathology ; surgery ; Female ; Follow-Up Studies ; Humans ; Liver Neoplasms ; secondary ; Male ; Middle Aged ; Neoplasm Invasiveness ; Neoplasm Recurrence, Local ; Pancreaticoduodenectomy ; Retrospective Studies ; Survival Rate
4.Carcinosarcoma of common bile duct: report of a case.
Chinese Journal of Pathology 2006;35(3):192-192
5.Carcinoid tumor of common bile duct: report of a case in pediatric patient.
Lan-yun SONG ; Xiao-li HU ; Lin-sheng ZHAO ; Pei-ru NING
Chinese Journal of Pathology 2011;40(1):54-55
Adenocarcinoma
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metabolism
;
pathology
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Carcinoid Tumor
;
metabolism
;
pathology
;
surgery
;
Child
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Chromogranin A
;
metabolism
;
Common Bile Duct
;
pathology
;
surgery
;
Common Bile Duct Neoplasms
;
metabolism
;
pathology
;
surgery
;
Diagnosis, Differential
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Duodenum
;
pathology
;
surgery
;
Gallbladder
;
pathology
;
surgery
;
Humans
;
Keratins
;
metabolism
;
Lymphoma
;
metabolism
;
pathology
;
Male
;
Mucin-1
;
metabolism
;
Neoplasm Invasiveness
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Rhabdomyosarcoma
;
metabolism
;
pathology
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Stomach
;
pathology
;
surgery
;
Synaptophysin
;
metabolism
6.Hepatoma presenting as extrahepatic biliary obstruction due to hemobilia.
Byoung Seon RHOE ; Hoguen KIM ; So Young JIN ; Woo Ick JANG
Yonsei Medical Journal 1989;30(4):383-386
A case of hepatoma presenting as extrahepatic biliary obstruction due to hemobilia is reported. The patient, a 49-year-old woman, developed jaundice of the obstructive type after a history of B-viral hepatitis. On laparotomy, the liver revealed macronodular cirrhosis without any noticeable mass. A 4-cm sized friable tissue and blood clots were identified within the distended left hepatic duct. Pathologic examination of this tissue confirmed the diagnosis of hepatocellular carcinoma extended in the hepatic duct.
Bile Duct Obstruction, Extrahepatic/*etiology/pathology
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Biopsy
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Carcinoma, Hepatocellular/*complications/pathology/surgery
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Case Report
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Common Bile Duct/pathology
;
Female
;
Hemobilia/*complications
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Human
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Liver Cirrhosis/diagnosis
;
Liver Neoplasms
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Middle Age
7.Hepatoma presenting as extrahepatic biliary obstruction due to hemobilia.
Byoung Seon RHOE ; Hoguen KIM ; So Young JIN ; Woo Ick JANG
Yonsei Medical Journal 1989;30(4):383-386
A case of hepatoma presenting as extrahepatic biliary obstruction due to hemobilia is reported. The patient, a 49-year-old woman, developed jaundice of the obstructive type after a history of B-viral hepatitis. On laparotomy, the liver revealed macronodular cirrhosis without any noticeable mass. A 4-cm sized friable tissue and blood clots were identified within the distended left hepatic duct. Pathologic examination of this tissue confirmed the diagnosis of hepatocellular carcinoma extended in the hepatic duct.
Bile Duct Obstruction, Extrahepatic/*etiology/pathology
;
Biopsy
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Carcinoma, Hepatocellular/*complications/pathology/surgery
;
Case Report
;
Common Bile Duct/pathology
;
Female
;
Hemobilia/*complications
;
Human
;
Liver Cirrhosis/diagnosis
;
Liver Neoplasms
;
Middle Age
8.A Case of Adenocarcinoma in situ of the Distal Common Bile Duct Diagnosed by Percutaneous Transhepatic Cholangioscopy.
Hyo Joon YANG ; Jai Hwan KIM ; Jae Young CHUN ; Su Jin KIM ; Sang Hyub LEE ; Haeryoung KIM ; Jin Hyeok HWANG
The Korean Journal of Internal Medicine 2012;27(2):211-215
Extrahepatic cholangiocarcinoma is often clinically challenging to diagnose. Even multidisciplinary approaches which include computed tomography, magnetic resonance imaging, and endoscopic retrograde cholangiography are unsatisfactory in some cases, especially with biliary stricture. Percutaneous transhepatic cholangioscopy (PTCS) with its direct visualization for biopsy appears to be a promising technique for detecting cholangiocarcinoma at an early stage. We report a case of adenocarcinoma in situ of the distal common bile duct (CBD) that was confirmed by PTCS. This case suggests the useful role of PTCS in the differential diagnosis of a distal CBD obstruction, particularly when other diagnostic modalities do not provide definitive information.
Carcinoma in Situ/complications/*diagnosis/pathology/surgery
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Cholangiocarcinoma/complications/*diagnosis/pathology/surgery
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Cholangiopancreatography, Endoscopic Retrograde
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Cholestasis, Extrahepatic/diagnosis/etiology
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Common Bile Duct/*pathology/surgery
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Common Bile Duct Neoplasms/complications/*diagnosis/pathology/surgery
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Constriction, Pathologic
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*Endoscopy, Digestive System
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Humans
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Male
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Middle Aged
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Pancreaticoduodenectomy
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Predictive Value of Tests
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Tomography, X-Ray Computed
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Treatment Outcome
9.Metachronous Four Primary Malignancies in Gastro-intestinal Tract.
Jung Min BAE ; Se Won KIM ; Sang Woon KIM ; Sun Kyo SONG
The Korean Journal of Gastroenterology 2009;53(6):373-377
Multiple primary malignancy was reported firstly by Billroth in 1889. Recently, multiple primary malignancies are considered to increase due to improved survival rate of cancer patients, advanced diagnostic tools, and increased use of chemotherapy and radiotherapy. In Korea, several cases of triple primary malignancies were reported. However, four primary malignancies in gastro-intestinal tract was rarely reported. Recently, we experienced a 70 year-old male who was diagnosed with metachronous four primary malignancies in rectum, ascending colon, stomach, and ampulla of Vater. We report this rare case of metachronous four primary malignancies with a review of literature.
Adenocarcinoma/*diagnosis/pathology/surgery
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Adenocarcinoma, Mucinous/diagnosis/surgery
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Aged
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Ampulla of Vater/*pathology
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Colonic Neoplasms/diagnosis/surgery
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Common Bile Duct Neoplasms/*diagnosis/pathology/surgery
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Gastrointestinal Neoplasms/*diagnosis/pathology/radiography
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Humans
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Male
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Neoplasms, Second Primary/*diagnosis/pathology
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Rectal Neoplasms/diagnosis/surgery
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Stomach Neoplasms/diagnosis/pathology/surgery
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Tomography, X-Ray Computed
10.A Case of Hepatectomy for Liver Metastasis after Pancreatoduodenectomy for Carcinoma of Ampulla of Vater.
Jeong A SHIN ; Min AN ; Joon Il CHOI ; Seong Hoon KIM ; Woo Jin LEE ; Sang Jae PARK ; Joong Won PARK ; Eun Kyung HONG
The Korean Journal of Gastroenterology 2006;48(6):434-437
After curative resection of carcinoma of ampulla of Vater, 5-year survival rate has been reported ranging from 40% to 60%. Two major causes of the treatment failure are local recurrence and liver metastasis. Liver metastases are often multiple and are associated with poor prognosis. There have been few reports on long-term survivors after hepatectomy for metastatic liver tumors from carcinoma of ampulla of Vater. We report a 42 year-old female patient with solitary hepatic metastasis from carcinoma of ampulla of Vater, which was successfully treated by hepatectomy 69 months after curative Whipple's operation. Histologic examination of the resected specimen had revealed stage IB moderately-differentiated, intestinal type adenocarcinoma (T2N0M0). Since neither local recurrence or distant metastasis were detected, the patient underwent liver segmentectomy. Histologic study confirmed the presence of metastatic liver tumor from carcinoma of ampulla of Vater. She is doing well without evidence of recurrence at 20 months after hepatectomy.
Adult
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*Ampulla of Vater
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Carcinoma/*diagnosis/secondary/*surgery
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Common Bile Duct Neoplasms/diagnosis/*pathology/surgery
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Female
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*Hepatectomy
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Humans
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Liver Neoplasms/*diagnosis/secondary/*surgery
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Pancreaticoduodenectomy
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Positron-Emission Tomography
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Tomography, X-Ray Computed